The Role of Some Immunological and Hematological Aspects in Patients Infected with COVID-19 in Al-Anbar Province

Hazima Mossa Alabassi; Dhyauldeen Aftan AlHayani; Omar Ismael Aljuamili; Anwar Khalil Ismael

doi:doi:10.11648/j.abb.20231102.11

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The Role of Some Immunological and Hematological Aspects in Patients Infected with COVID-19 in Al-Anbar Province

Hazima Mossa Alabassi, Dhyauldeen Aftan AlHayani, Omar Ismael Aljuamili, Anwar Khalil Ismael

Published in Advances in Bioscience and Bioengineering (Volume 11, Issue 2)

Received: 30 June 2023 Accepted: 17 July 2023 Published: 26 July 2023

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Abstract

The study aimed to evaluate the immune response, its effect on the coagulant system and the outcome of infection with COVID-19 in two groups (convalescent & severe patients) and healthy individuals groups, 88 blood samples were collected (30 for convalescent and 30 for severe) and 28 for control. All patients with age range (19-70) years with COVID-19 mild and severe symptoms, attended at Ramadi city hospitals, from April 2020 to August 2020, (ELISA) technique was carried out to assess the serum levels of (IL-23 and IL-27) in addition to assess some of the coagulant factors such as ferritin, D-Dimer, CBC, Viral load (Anti SARS CoV-2 antibodies IgM and IgG), C-reactive protein and Erythrocyte sedimentation rate. The results showed that platelet observed decreasing levels in two patient groups (convalescent and severe compare with control). IgM recorded the high levels in severe cases which IgG high in convalescent cases, WBCs, Lymphocyte, Monocyte recorded a decreased count in severe and with no difference between convalescent and control, while Neutrophil count recorded a slight increase in convalescent when compared to controls, the cytokine IL-23 showed a highly significant increase in extreme and a significant increase in convalescent. Also, IL-27 recorded highly significant differences in severe and significant increases in convalescent compare with control. The coagulant factor system (ferritin, D-Dimer, ESR, and CRP) recorded a highly significant increase in severe compare with control, while in convalescent recorded a slight increase in serum levels of ESR and CRP with no difference in ferritin serum level, except D-Dimer which recorded a highly significant difference as compared with control, finally regard to gender male recorded the highest rate of infection as compared with female.

Published in	Advances in Bioscience and Bioengineering (Volume 11, Issue 2)
DOI	10.11648/j.abb.20231102.11
Page(s)	21-26
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

COVID-19, Immunological, Hematological, IL-23, IL-27

References

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APA Style

Hazima Mossa Alabassi, Dhyauldeen Aftan AlHayani, Omar Ismael Aljuamili, Anwar Khalil Ismael. (2023). The Role of Some Immunological and Hematological Aspects in Patients Infected with COVID-19 in Al-Anbar Province. Advances in Bioscience and Bioengineering, 11(2), 21-26. https://doi.org/10.11648/j.abb.20231102.11

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ACS Style

Hazima Mossa Alabassi; Dhyauldeen Aftan AlHayani; Omar Ismael Aljuamili; Anwar Khalil Ismael. The Role of Some Immunological and Hematological Aspects in Patients Infected with COVID-19 in Al-Anbar Province. Adv. BioSci. Bioeng. 2023, 11(2), 21-26. doi: 10.11648/j.abb.20231102.11

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AMA Style

Hazima Mossa Alabassi, Dhyauldeen Aftan AlHayani, Omar Ismael Aljuamili, Anwar Khalil Ismael. The Role of Some Immunological and Hematological Aspects in Patients Infected with COVID-19 in Al-Anbar Province. Adv BioSci Bioeng. 2023;11(2):21-26. doi: 10.11648/j.abb.20231102.11

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@article{10.11648/j.abb.20231102.11,
  author = {Hazima Mossa Alabassi and Dhyauldeen Aftan AlHayani and Omar Ismael Aljuamili and Anwar Khalil Ismael},
  title = {The Role of Some Immunological and Hematological Aspects in Patients Infected with COVID-19 in Al-Anbar Province},
  journal = {Advances in Bioscience and Bioengineering},
  volume = {11},
  number = {2},
  pages = {21-26},
  doi = {10.11648/j.abb.20231102.11},
  url = {https://doi.org/10.11648/j.abb.20231102.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.abb.20231102.11},
  abstract = {The study aimed to evaluate the immune response, its effect on the coagulant system and the outcome of infection with COVID-19 in two groups (convalescent & severe patients) and healthy individuals groups, 88 blood samples were collected (30 for convalescent and 30 for severe) and 28 for control. All patients with age range (19-70) years with COVID-19 mild and severe symptoms, attended at Ramadi city hospitals, from April 2020 to August 2020, (ELISA) technique was carried out to assess the serum levels of (IL-23 and IL-27) in addition to assess some of the coagulant factors such as ferritin, D-Dimer, CBC, Viral load (Anti SARS CoV-2 antibodies IgM and IgG), C-reactive protein and Erythrocyte sedimentation rate. The results showed that platelet observed decreasing levels in two patient groups (convalescent and severe compare with control). IgM recorded the high levels in severe cases which IgG high in convalescent cases, WBCs, Lymphocyte, Monocyte recorded a decreased count in severe and with no difference between convalescent and control, while Neutrophil count recorded a slight increase in convalescent when compared to controls, the cytokine IL-23 showed a highly significant increase in extreme and a significant increase in convalescent. Also, IL-27 recorded highly significant differences in severe and significant increases in convalescent compare with control. The coagulant factor system (ferritin, D-Dimer, ESR, and CRP) recorded a highly significant increase in severe compare with control, while in convalescent recorded a slight increase in serum levels of ESR and CRP with no difference in ferritin serum level, except D-Dimer which recorded a highly significant difference as compared with control, finally regard to gender male recorded the highest rate of infection as compared with female.},
 year = {2023}
}

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TY  - JOUR
T1  - The Role of Some Immunological and Hematological Aspects in Patients Infected with COVID-19 in Al-Anbar Province
AU  - Hazima Mossa Alabassi
AU  - Dhyauldeen Aftan AlHayani
AU  - Omar Ismael Aljuamili
AU  - Anwar Khalil Ismael
Y1  - 2023/07/26
PY  - 2023
N1  - https://doi.org/10.11648/j.abb.20231102.11
DO  - 10.11648/j.abb.20231102.11
T2  - Advances in Bioscience and Bioengineering
JF  - Advances in Bioscience and Bioengineering
JO  - Advances in Bioscience and Bioengineering
SP  - 21
EP  - 26
PB  - Science Publishing Group
SN  - 2330-4162
UR  - https://doi.org/10.11648/j.abb.20231102.11
AB  - The study aimed to evaluate the immune response, its effect on the coagulant system and the outcome of infection with COVID-19 in two groups (convalescent & severe patients) and healthy individuals groups, 88 blood samples were collected (30 for convalescent and 30 for severe) and 28 for control. All patients with age range (19-70) years with COVID-19 mild and severe symptoms, attended at Ramadi city hospitals, from April 2020 to August 2020, (ELISA) technique was carried out to assess the serum levels of (IL-23 and IL-27) in addition to assess some of the coagulant factors such as ferritin, D-Dimer, CBC, Viral load (Anti SARS CoV-2 antibodies IgM and IgG), C-reactive protein and Erythrocyte sedimentation rate. The results showed that platelet observed decreasing levels in two patient groups (convalescent and severe compare with control). IgM recorded the high levels in severe cases which IgG high in convalescent cases, WBCs, Lymphocyte, Monocyte recorded a decreased count in severe and with no difference between convalescent and control, while Neutrophil count recorded a slight increase in convalescent when compared to controls, the cytokine IL-23 showed a highly significant increase in extreme and a significant increase in convalescent. Also, IL-27 recorded highly significant differences in severe and significant increases in convalescent compare with control. The coagulant factor system (ferritin, D-Dimer, ESR, and CRP) recorded a highly significant increase in severe compare with control, while in convalescent recorded a slight increase in serum levels of ESR and CRP with no difference in ferritin serum level, except D-Dimer which recorded a highly significant difference as compared with control, finally regard to gender male recorded the highest rate of infection as compared with female.
VL  - 11
IS  - 2
ER  -

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Author Information

Hazima Mossa Alabassi

Department of Biology, College of Education for Pure Science (Ibn Al-Haitham), University of Baghdad, Baghdad, Iraq
Dhyauldeen Aftan AlHayani

Ministry of Health, Higher Institute for Professional Nursing, Al-Ramadi, Iraq
Omar Ismael Aljuamili

Ministry of Health of Iraq, Al-Anbar Health Directorate, Al-Ramadi, Iraq
Anwar Khalil Ismael

Department of Analytic Pathology, College of Applied Science, University of Fallujah, Al-Fallujah, Iraq

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Hazima Mossa Alabassi, Dhyauldeen Aftan AlHayani, Omar Ismael Aljuamili, Anwar Khalil Ismael. (2023). The Role of Some Immunological and Hematological Aspects in Patients Infected with COVID-19 in Al-Anbar Province. Advances in Bioscience and Bioengineering, 11(2), 21-26. https://doi.org/10.11648/j.abb.20231102.11

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ACS Style

Hazima Mossa Alabassi; Dhyauldeen Aftan AlHayani; Omar Ismael Aljuamili; Anwar Khalil Ismael. The Role of Some Immunological and Hematological Aspects in Patients Infected with COVID-19 in Al-Anbar Province. Adv. BioSci. Bioeng. 2023, 11(2), 21-26. doi: 10.11648/j.abb.20231102.11

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AMA Style

Hazima Mossa Alabassi, Dhyauldeen Aftan AlHayani, Omar Ismael Aljuamili, Anwar Khalil Ismael. The Role of Some Immunological and Hematological Aspects in Patients Infected with COVID-19 in Al-Anbar Province. Adv BioSci Bioeng. 2023;11(2):21-26. doi: 10.11648/j.abb.20231102.11

Copy | Download

@article{10.11648/j.abb.20231102.11,
  author = {Hazima Mossa Alabassi and Dhyauldeen Aftan AlHayani and Omar Ismael Aljuamili and Anwar Khalil Ismael},
  title = {The Role of Some Immunological and Hematological Aspects in Patients Infected with COVID-19 in Al-Anbar Province},
  journal = {Advances in Bioscience and Bioengineering},
  volume = {11},
  number = {2},
  pages = {21-26},
  doi = {10.11648/j.abb.20231102.11},
  url = {https://doi.org/10.11648/j.abb.20231102.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.abb.20231102.11},
  abstract = {The study aimed to evaluate the immune response, its effect on the coagulant system and the outcome of infection with COVID-19 in two groups (convalescent & severe patients) and healthy individuals groups, 88 blood samples were collected (30 for convalescent and 30 for severe) and 28 for control. All patients with age range (19-70) years with COVID-19 mild and severe symptoms, attended at Ramadi city hospitals, from April 2020 to August 2020, (ELISA) technique was carried out to assess the serum levels of (IL-23 and IL-27) in addition to assess some of the coagulant factors such as ferritin, D-Dimer, CBC, Viral load (Anti SARS CoV-2 antibodies IgM and IgG), C-reactive protein and Erythrocyte sedimentation rate. The results showed that platelet observed decreasing levels in two patient groups (convalescent and severe compare with control). IgM recorded the high levels in severe cases which IgG high in convalescent cases, WBCs, Lymphocyte, Monocyte recorded a decreased count in severe and with no difference between convalescent and control, while Neutrophil count recorded a slight increase in convalescent when compared to controls, the cytokine IL-23 showed a highly significant increase in extreme and a significant increase in convalescent. Also, IL-27 recorded highly significant differences in severe and significant increases in convalescent compare with control. The coagulant factor system (ferritin, D-Dimer, ESR, and CRP) recorded a highly significant increase in severe compare with control, while in convalescent recorded a slight increase in serum levels of ESR and CRP with no difference in ferritin serum level, except D-Dimer which recorded a highly significant difference as compared with control, finally regard to gender male recorded the highest rate of infection as compared with female.},
 year = {2023}
}

Copy | Download

TY  - JOUR
T1  - The Role of Some Immunological and Hematological Aspects in Patients Infected with COVID-19 in Al-Anbar Province
AU  - Hazima Mossa Alabassi
AU  - Dhyauldeen Aftan AlHayani
AU  - Omar Ismael Aljuamili
AU  - Anwar Khalil Ismael
Y1  - 2023/07/26
PY  - 2023
N1  - https://doi.org/10.11648/j.abb.20231102.11
DO  - 10.11648/j.abb.20231102.11
T2  - Advances in Bioscience and Bioengineering
JF  - Advances in Bioscience and Bioengineering
JO  - Advances in Bioscience and Bioengineering
SP  - 21
EP  - 26
PB  - Science Publishing Group
SN  - 2330-4162
UR  - https://doi.org/10.11648/j.abb.20231102.11
AB  - The study aimed to evaluate the immune response, its effect on the coagulant system and the outcome of infection with COVID-19 in two groups (convalescent & severe patients) and healthy individuals groups, 88 blood samples were collected (30 for convalescent and 30 for severe) and 28 for control. All patients with age range (19-70) years with COVID-19 mild and severe symptoms, attended at Ramadi city hospitals, from April 2020 to August 2020, (ELISA) technique was carried out to assess the serum levels of (IL-23 and IL-27) in addition to assess some of the coagulant factors such as ferritin, D-Dimer, CBC, Viral load (Anti SARS CoV-2 antibodies IgM and IgG), C-reactive protein and Erythrocyte sedimentation rate. The results showed that platelet observed decreasing levels in two patient groups (convalescent and severe compare with control). IgM recorded the high levels in severe cases which IgG high in convalescent cases, WBCs, Lymphocyte, Monocyte recorded a decreased count in severe and with no difference between convalescent and control, while Neutrophil count recorded a slight increase in convalescent when compared to controls, the cytokine IL-23 showed a highly significant increase in extreme and a significant increase in convalescent. Also, IL-27 recorded highly significant differences in severe and significant increases in convalescent compare with control. The coagulant factor system (ferritin, D-Dimer, ESR, and CRP) recorded a highly significant increase in severe compare with control, while in convalescent recorded a slight increase in serum levels of ESR and CRP with no difference in ferritin serum level, except D-Dimer which recorded a highly significant difference as compared with control, finally regard to gender male recorded the highest rate of infection as compared with female.
VL  - 11
IS  - 2
ER  -

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