Effectiveness of Intrauterine Insemination in Unexplained Infertility and Male Subfertility with Mild Form of Oligo Asthenoteratozoospermia

Masuma Amanullah; Mohammad Akram Ahsan; Mohammad Saiful Akram; Mohammad Samsul Arefin; Farhana Hasan; Sadia Tabassum

doi:doi:10.11648/j.ajasr.20220804.15

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Effectiveness of Intrauterine Insemination in Unexplained Infertility and Male Subfertility with Mild Form of Oligo Asthenoteratozoospermia

Masuma Amanullah, Mohammad Akram Ahsan, Mohammad Saiful Akram, Mohammad Samsul Arefin, Farhana Hasan, Sadia Tabassum

Published in American Journal of Applied Scientific Research (Volume 8, Issue 4)

Received: 1 September 2022 Accepted: 30 September 2022 Published: 30 November 2022

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Abstract

Introduction: Male infertility is typically determined through routine sperm analysis, but recent publications have called into question its diagnostic and prognostic accuracy, as well as the effectiveness of IUI itself. The aim of the study was to evaluate the pregnancy rate following IUI in unexplained infertility and male infertility (a mild form of oligo astheno teratozoospermia). Methods: This interventional study was carried out in the outpatient department (OPD) of the infertility Unit of Gynaecology and Obstetrics Department of Bangabandhu Sheikh Mujib Medical University, Dhaka, from July 2014 to June 2015. A total of 148 couples were enrolled, out of which 74 couples where only a male partner had oligospermia or asthenozoospermia or teratozoospermia were considered group I (case) and 74 couples had unexplained infertility was considered group II (control). All-female patients took Tab clomiphene citrate 100mg from D2-D5 and inj Menogon (75IU) I/M was received on D3 and D8. TVS for folliculometry was done from D9 onwards every alternate day. Statistical analysis of the results was obtained by using windows computer software with Statistical Packages for Social Sciences (SPSS-version 22). Result: Follicle was developed (≥17 mm) in 71 (96.0%) in group I and 68 (91.9%) in group II up to D₁₃. Pre-wash motility <50 percent was found in all cases in group II and group II respectively. Post motility ≥50 percent was found in 10 (15.6%) in group I. The difference was statistically significant (p<0.05) between the two groups. Biochemical pregnancy occurs 3 (4.7%) in group I and 5 (8.5%) in group II. Clinical pregnancy 2 (3.1%) and 3 (5.1%) in group I and group II respectively. Biochemical and Clinical pregnancy differences were not statistically significant (p>0.05) between the two groups. Conclusion: Stimulated IUI should be the first choice treatment for mild male factor infertility, and unexplained infertility, which is a less costly and easy procedure. it can be done before going through more invasive and costly treatments like IVF or ICSI.

Published in	American Journal of Applied Scientific Research (Volume 8, Issue 4)
DOI	10.11648/j.ajasr.20220804.15
Page(s)	99-106
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Intrauterine Insemination, Infertility, Subfertility, Oligo Asthenoteratozoospermia

References

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Masuma Amanullah, Mohammad Akram Ahsan, Mohammad Saiful Akram, Mohammad Samsul Arefin, Farhana Hasan, et al. (2022). Effectiveness of Intrauterine Insemination in Unexplained Infertility and Male Subfertility with Mild Form of Oligo Asthenoteratozoospermia. American Journal of Applied Scientific Research, 8(4), 99-106. https://doi.org/10.11648/j.ajasr.20220804.15

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Masuma Amanullah; Mohammad Akram Ahsan; Mohammad Saiful Akram; Mohammad Samsul Arefin; Farhana Hasan, et al. Effectiveness of Intrauterine Insemination in Unexplained Infertility and Male Subfertility with Mild Form of Oligo Asthenoteratozoospermia. Am. J. Appl. Sci. Res. 2022, 8(4), 99-106. doi: 10.11648/j.ajasr.20220804.15

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Masuma Amanullah, Mohammad Akram Ahsan, Mohammad Saiful Akram, Mohammad Samsul Arefin, Farhana Hasan, et al. Effectiveness of Intrauterine Insemination in Unexplained Infertility and Male Subfertility with Mild Form of Oligo Asthenoteratozoospermia. Am J Appl Sci Res. 2022;8(4):99-106. doi: 10.11648/j.ajasr.20220804.15

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@article{10.11648/j.ajasr.20220804.15,
  author = {Masuma Amanullah and Mohammad Akram Ahsan and Mohammad Saiful Akram and Mohammad Samsul Arefin and Farhana Hasan and Sadia Tabassum},
  title = {Effectiveness of Intrauterine Insemination in Unexplained Infertility and Male Subfertility with Mild Form of Oligo Asthenoteratozoospermia},
  journal = {American Journal of Applied Scientific Research},
  volume = {8},
  number = {4},
  pages = {99-106},
  doi = {10.11648/j.ajasr.20220804.15},
  url = {https://doi.org/10.11648/j.ajasr.20220804.15},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajasr.20220804.15},
  abstract = {Introduction: Male infertility is typically determined through routine sperm analysis, but recent publications have called into question its diagnostic and prognostic accuracy, as well as the effectiveness of IUI itself. The aim of the study was to evaluate the pregnancy rate following IUI in unexplained infertility and male infertility (a mild form of oligo astheno teratozoospermia). Methods: This interventional study was carried out in the outpatient department (OPD) of the infertility Unit of Gynaecology and Obstetrics Department of Bangabandhu Sheikh Mujib Medical University, Dhaka, from July 2014 to June 2015. A total of 148 couples were enrolled, out of which 74 couples where only a male partner had oligospermia or asthenozoospermia or teratozoospermia were considered group I (case) and 74 couples had unexplained infertility was considered group II (control). All-female patients took Tab clomiphene citrate 100mg from D2-D5 and inj Menogon (75IU) I/M was received on D3 and D8. TVS for folliculometry was done from D9 onwards every alternate day. Statistical analysis of the results was obtained by using windows computer software with Statistical Packages for Social Sciences (SPSS-version 22). Result: Follicle was developed (≥17 mm) in 71 (96.0%) in group I and 68 (91.9%) in group II up to D13. Pre-wash motility 0.05) between the two groups. Conclusion: Stimulated IUI should be the first choice treatment for mild male factor infertility, and unexplained infertility, which is a less costly and easy procedure. it can be done before going through more invasive and costly treatments like IVF or ICSI.},
 year = {2022}
}

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TY  - JOUR
T1  - Effectiveness of Intrauterine Insemination in Unexplained Infertility and Male Subfertility with Mild Form of Oligo Asthenoteratozoospermia
AU  - Masuma Amanullah
AU  - Mohammad Akram Ahsan
AU  - Mohammad Saiful Akram
AU  - Mohammad Samsul Arefin
AU  - Farhana Hasan
AU  - Sadia Tabassum
Y1  - 2022/11/30
PY  - 2022
N1  - https://doi.org/10.11648/j.ajasr.20220804.15
DO  - 10.11648/j.ajasr.20220804.15
T2  - American Journal of Applied Scientific Research
JF  - American Journal of Applied Scientific Research
JO  - American Journal of Applied Scientific Research
SP  - 99
EP  - 106
PB  - Science Publishing Group
SN  - 2471-9730
UR  - https://doi.org/10.11648/j.ajasr.20220804.15
AB  - Introduction: Male infertility is typically determined through routine sperm analysis, but recent publications have called into question its diagnostic and prognostic accuracy, as well as the effectiveness of IUI itself. The aim of the study was to evaluate the pregnancy rate following IUI in unexplained infertility and male infertility (a mild form of oligo astheno teratozoospermia). Methods: This interventional study was carried out in the outpatient department (OPD) of the infertility Unit of Gynaecology and Obstetrics Department of Bangabandhu Sheikh Mujib Medical University, Dhaka, from July 2014 to June 2015. A total of 148 couples were enrolled, out of which 74 couples where only a male partner had oligospermia or asthenozoospermia or teratozoospermia were considered group I (case) and 74 couples had unexplained infertility was considered group II (control). All-female patients took Tab clomiphene citrate 100mg from D2-D5 and inj Menogon (75IU) I/M was received on D3 and D8. TVS for folliculometry was done from D9 onwards every alternate day. Statistical analysis of the results was obtained by using windows computer software with Statistical Packages for Social Sciences (SPSS-version 22). Result: Follicle was developed (≥17 mm) in 71 (96.0%) in group I and 68 (91.9%) in group II up to D13. Pre-wash motility 0.05) between the two groups. Conclusion: Stimulated IUI should be the first choice treatment for mild male factor infertility, and unexplained infertility, which is a less costly and easy procedure. it can be done before going through more invasive and costly treatments like IVF or ICSI.
VL  - 8
IS  - 4
ER  -

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Author Information

Masuma Amanullah

Department of Gynecology, Tarail Upazila Health Complex, Kishorganj, Bangladesh
Mohammad Akram Ahsan

Department of Dermatology and Venerology, Shaheed Syed Nazrul Islam Medical College Hospital, Kishorganj, Bangladesh
Mohammad Saiful Akram

Department of Ear, Nose, and Throat, National Institute of Ear, Nose, and Throat, Tejgaon, Bangladesh
Mohammad Samsul Arefin

Department of Anesthesia, National Institute of Neurosciences and Hospital, Agargaon, Bangladesh
Farhana Hasan

Department of Statistics, University of Rajshahi, Rajshahi, Bangladesh
Sadia Tabassum

Department of Pediatrics Neurology and Development, Shaheed Suhrawardy Medical College and Hospital, Dhaka, Bangladesh

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Masuma Amanullah, Mohammad Akram Ahsan, Mohammad Saiful Akram, Mohammad Samsul Arefin, Farhana Hasan, et al. (2022). Effectiveness of Intrauterine Insemination in Unexplained Infertility and Male Subfertility with Mild Form of Oligo Asthenoteratozoospermia. American Journal of Applied Scientific Research, 8(4), 99-106. https://doi.org/10.11648/j.ajasr.20220804.15

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ACS Style

Masuma Amanullah; Mohammad Akram Ahsan; Mohammad Saiful Akram; Mohammad Samsul Arefin; Farhana Hasan, et al. Effectiveness of Intrauterine Insemination in Unexplained Infertility and Male Subfertility with Mild Form of Oligo Asthenoteratozoospermia. Am. J. Appl. Sci. Res. 2022, 8(4), 99-106. doi: 10.11648/j.ajasr.20220804.15

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AMA Style

Masuma Amanullah, Mohammad Akram Ahsan, Mohammad Saiful Akram, Mohammad Samsul Arefin, Farhana Hasan, et al. Effectiveness of Intrauterine Insemination in Unexplained Infertility and Male Subfertility with Mild Form of Oligo Asthenoteratozoospermia. Am J Appl Sci Res. 2022;8(4):99-106. doi: 10.11648/j.ajasr.20220804.15

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@article{10.11648/j.ajasr.20220804.15,
  author = {Masuma Amanullah and Mohammad Akram Ahsan and Mohammad Saiful Akram and Mohammad Samsul Arefin and Farhana Hasan and Sadia Tabassum},
  title = {Effectiveness of Intrauterine Insemination in Unexplained Infertility and Male Subfertility with Mild Form of Oligo Asthenoteratozoospermia},
  journal = {American Journal of Applied Scientific Research},
  volume = {8},
  number = {4},
  pages = {99-106},
  doi = {10.11648/j.ajasr.20220804.15},
  url = {https://doi.org/10.11648/j.ajasr.20220804.15},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajasr.20220804.15},
  abstract = {Introduction: Male infertility is typically determined through routine sperm analysis, but recent publications have called into question its diagnostic and prognostic accuracy, as well as the effectiveness of IUI itself. The aim of the study was to evaluate the pregnancy rate following IUI in unexplained infertility and male infertility (a mild form of oligo astheno teratozoospermia). Methods: This interventional study was carried out in the outpatient department (OPD) of the infertility Unit of Gynaecology and Obstetrics Department of Bangabandhu Sheikh Mujib Medical University, Dhaka, from July 2014 to June 2015. A total of 148 couples were enrolled, out of which 74 couples where only a male partner had oligospermia or asthenozoospermia or teratozoospermia were considered group I (case) and 74 couples had unexplained infertility was considered group II (control). All-female patients took Tab clomiphene citrate 100mg from D2-D5 and inj Menogon (75IU) I/M was received on D3 and D8. TVS for folliculometry was done from D9 onwards every alternate day. Statistical analysis of the results was obtained by using windows computer software with Statistical Packages for Social Sciences (SPSS-version 22). Result: Follicle was developed (≥17 mm) in 71 (96.0%) in group I and 68 (91.9%) in group II up to D13. Pre-wash motility 0.05) between the two groups. Conclusion: Stimulated IUI should be the first choice treatment for mild male factor infertility, and unexplained infertility, which is a less costly and easy procedure. it can be done before going through more invasive and costly treatments like IVF or ICSI.},
 year = {2022}
}

Copy | Download

TY  - JOUR
T1  - Effectiveness of Intrauterine Insemination in Unexplained Infertility and Male Subfertility with Mild Form of Oligo Asthenoteratozoospermia
AU  - Masuma Amanullah
AU  - Mohammad Akram Ahsan
AU  - Mohammad Saiful Akram
AU  - Mohammad Samsul Arefin
AU  - Farhana Hasan
AU  - Sadia Tabassum
Y1  - 2022/11/30
PY  - 2022
N1  - https://doi.org/10.11648/j.ajasr.20220804.15
DO  - 10.11648/j.ajasr.20220804.15
T2  - American Journal of Applied Scientific Research
JF  - American Journal of Applied Scientific Research
JO  - American Journal of Applied Scientific Research
SP  - 99
EP  - 106
PB  - Science Publishing Group
SN  - 2471-9730
UR  - https://doi.org/10.11648/j.ajasr.20220804.15
AB  - Introduction: Male infertility is typically determined through routine sperm analysis, but recent publications have called into question its diagnostic and prognostic accuracy, as well as the effectiveness of IUI itself. The aim of the study was to evaluate the pregnancy rate following IUI in unexplained infertility and male infertility (a mild form of oligo astheno teratozoospermia). Methods: This interventional study was carried out in the outpatient department (OPD) of the infertility Unit of Gynaecology and Obstetrics Department of Bangabandhu Sheikh Mujib Medical University, Dhaka, from July 2014 to June 2015. A total of 148 couples were enrolled, out of which 74 couples where only a male partner had oligospermia or asthenozoospermia or teratozoospermia were considered group I (case) and 74 couples had unexplained infertility was considered group II (control). All-female patients took Tab clomiphene citrate 100mg from D2-D5 and inj Menogon (75IU) I/M was received on D3 and D8. TVS for folliculometry was done from D9 onwards every alternate day. Statistical analysis of the results was obtained by using windows computer software with Statistical Packages for Social Sciences (SPSS-version 22). Result: Follicle was developed (≥17 mm) in 71 (96.0%) in group I and 68 (91.9%) in group II up to D13. Pre-wash motility 0.05) between the two groups. Conclusion: Stimulated IUI should be the first choice treatment for mild male factor infertility, and unexplained infertility, which is a less costly and easy procedure. it can be done before going through more invasive and costly treatments like IVF or ICSI.
VL  - 8
IS  - 4
ER  -

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