Effects of Lisinopril and Amlodipine in Combination for the Treatment of Hypertension with Pulse Wave Velocity VP Plus 1000 Meter

Cao Truong Sinh; Hoang Ngoc Linh

doi:doi:10.11648/j.ajcem.20221003.11

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Effects of Lisinopril and Amlodipine in Combination for the Treatment of Hypertension with Pulse Wave Velocity VP Plus 1000 Meter

Cao Truong Sinh, Hoang Ngoc Linh

Published in American Journal of Clinical and Experimental Medicine (Volume 10, Issue 3)

Received: 24 April 2022 Accepted: 7 May 2022 Published: 12 May 2022

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Abstract

Aim: The aim of this study was to evaluate the antihypertensive efficacy of lisinopril and amlodipine in combination which were measured by the pulse wave velocity meter. Research objects and Methods: 40 patients with primary hypertension, mean age 69.18 ± 10.4 years. All patients had their blood pressure, pulse wave velocity (baWPV), ankle brachial index measured by pulse wave velocity VP Plus 1000 meter before receiving the treatment. All patients were then given the Lisonorm combination pill (lisinopril 10 mg and amlodipine 5 mg) for 4 weeks. After 4 weeks, the patients was measured again with the same device (the pulse wave velocity of VP Plus 1000 meter). Results: After 4 weeks, the values of the Right arm blood pressure decreased: 26.58 ± 9.51 mmHg/ 8.6 ± 4.47 mmHg; Left arm blood pressure decreased: 26.88 ± 11.27/13.55 ± 8.15mmHg; Right ankle blood pressure decreased: 23.75 ± 11.78/10.75 ± 6.64mmHg; Left ankle blood pressure decreased: 30.33 ± 16.64/13.6 ± 9.28mmHg; The rate of patients with the target blood pressure was 72.5% (29/40 patients). Right baPWV decreased 593.65 ± 416.59 cm/s; Left baPWV decreased 585.4 ± 447.19 cm/s. Conclusion: The combination of lisinopril 10mg and amlodipine 5mg effectively had decreased the blood pressure in both extremities and pulse wave velocity, and had reduced vessel wall stiffness when it was measured by the pulse wave velocity VP Plus 1000 meter.

Published in	American Journal of Clinical and Experimental Medicine (Volume 10, Issue 3)
DOI	10.11648/j.ajcem.20221003.11
Page(s)	67-73
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Hypertension (HTN), Combination Pill (Lisinopril and Amlodipine), Arm Blood Pressure (BP), Ankle Blood Pressure, Pulse Wave Velocity (WPV), Target Blood Pressure (TBP)

References

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APA Style

Cao Truong Sinh, Hoang Ngoc Linh. (2022). Effects of Lisinopril and Amlodipine in Combination for the Treatment of Hypertension with Pulse Wave Velocity VP Plus 1000 Meter. American Journal of Clinical and Experimental Medicine, 10(3), 67-73. https://doi.org/10.11648/j.ajcem.20221003.11

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ACS Style

Cao Truong Sinh; Hoang Ngoc Linh. Effects of Lisinopril and Amlodipine in Combination for the Treatment of Hypertension with Pulse Wave Velocity VP Plus 1000 Meter. Am. J. Clin. Exp. Med. 2022, 10(3), 67-73. doi: 10.11648/j.ajcem.20221003.11

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AMA Style

Cao Truong Sinh, Hoang Ngoc Linh. Effects of Lisinopril and Amlodipine in Combination for the Treatment of Hypertension with Pulse Wave Velocity VP Plus 1000 Meter. Am J Clin Exp Med. 2022;10(3):67-73. doi: 10.11648/j.ajcem.20221003.11

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@article{10.11648/j.ajcem.20221003.11,
  author = {Cao Truong Sinh and Hoang Ngoc Linh},
  title = {Effects of Lisinopril and Amlodipine in Combination for the Treatment of Hypertension with Pulse Wave Velocity VP Plus 1000 Meter},
  journal = {American Journal of Clinical and Experimental Medicine},
  volume = {10},
  number = {3},
  pages = {67-73},
  doi = {10.11648/j.ajcem.20221003.11},
  url = {https://doi.org/10.11648/j.ajcem.20221003.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajcem.20221003.11},
  abstract = {Aim: The aim of this study was to evaluate the antihypertensive efficacy of lisinopril and amlodipine in combination which were measured by the pulse wave velocity meter. Research objects and Methods: 40 patients with primary hypertension, mean age 69.18 ± 10.4 years. All patients had their blood pressure, pulse wave velocity (baWPV), ankle brachial index measured by pulse wave velocity VP Plus 1000 meter before receiving the treatment. All patients were then given the Lisonorm combination pill (lisinopril 10 mg and amlodipine 5 mg) for 4 weeks. After 4 weeks, the patients was measured again with the same device (the pulse wave velocity of VP Plus 1000 meter). Results: After 4 weeks, the values of the Right arm blood pressure decreased: 26.58 ± 9.51 mmHg/ 8.6 ± 4.47 mmHg; Left arm blood pressure decreased: 26.88 ± 11.27/13.55 ± 8.15mmHg; Right ankle blood pressure decreased: 23.75 ± 11.78/10.75 ± 6.64mmHg; Left ankle blood pressure decreased: 30.33 ± 16.64/13.6 ± 9.28mmHg; The rate of patients with the target blood pressure was 72.5% (29/40 patients). Right baPWV decreased 593.65 ± 416.59 cm/s; Left baPWV decreased 585.4 ± 447.19 cm/s. Conclusion: The combination of lisinopril 10mg and amlodipine 5mg effectively had decreased the blood pressure in both extremities and pulse wave velocity, and had reduced vessel wall stiffness when it was measured by the pulse wave velocity VP Plus 1000 meter.},
 year = {2022}
}

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TY  - JOUR
T1  - Effects of Lisinopril and Amlodipine in Combination for the Treatment of Hypertension with Pulse Wave Velocity VP Plus 1000 Meter
AU  - Cao Truong Sinh
AU  - Hoang Ngoc Linh
Y1  - 2022/05/12
PY  - 2022
N1  - https://doi.org/10.11648/j.ajcem.20221003.11
DO  - 10.11648/j.ajcem.20221003.11
T2  - American Journal of Clinical and Experimental Medicine
JF  - American Journal of Clinical and Experimental Medicine
JO  - American Journal of Clinical and Experimental Medicine
SP  - 67
EP  - 73
PB  - Science Publishing Group
SN  - 2330-8133
UR  - https://doi.org/10.11648/j.ajcem.20221003.11
AB  - Aim: The aim of this study was to evaluate the antihypertensive efficacy of lisinopril and amlodipine in combination which were measured by the pulse wave velocity meter. Research objects and Methods: 40 patients with primary hypertension, mean age 69.18 ± 10.4 years. All patients had their blood pressure, pulse wave velocity (baWPV), ankle brachial index measured by pulse wave velocity VP Plus 1000 meter before receiving the treatment. All patients were then given the Lisonorm combination pill (lisinopril 10 mg and amlodipine 5 mg) for 4 weeks. After 4 weeks, the patients was measured again with the same device (the pulse wave velocity of VP Plus 1000 meter). Results: After 4 weeks, the values of the Right arm blood pressure decreased: 26.58 ± 9.51 mmHg/ 8.6 ± 4.47 mmHg; Left arm blood pressure decreased: 26.88 ± 11.27/13.55 ± 8.15mmHg; Right ankle blood pressure decreased: 23.75 ± 11.78/10.75 ± 6.64mmHg; Left ankle blood pressure decreased: 30.33 ± 16.64/13.6 ± 9.28mmHg; The rate of patients with the target blood pressure was 72.5% (29/40 patients). Right baPWV decreased 593.65 ± 416.59 cm/s; Left baPWV decreased 585.4 ± 447.19 cm/s. Conclusion: The combination of lisinopril 10mg and amlodipine 5mg effectively had decreased the blood pressure in both extremities and pulse wave velocity, and had reduced vessel wall stiffness when it was measured by the pulse wave velocity VP Plus 1000 meter.
VL  - 10
IS  - 3
ER  -

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Author Information

Cao Truong Sinh

Department of Cardiology, Vinh Medical University Hospital, Vinh City, Vietnam
Hoang Ngoc Linh

Department of Cardiology, Vinh Medical University Hospital, Vinh City, Vietnam

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APA Style

Cao Truong Sinh, Hoang Ngoc Linh. (2022). Effects of Lisinopril and Amlodipine in Combination for the Treatment of Hypertension with Pulse Wave Velocity VP Plus 1000 Meter. American Journal of Clinical and Experimental Medicine, 10(3), 67-73. https://doi.org/10.11648/j.ajcem.20221003.11

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ACS Style

Cao Truong Sinh; Hoang Ngoc Linh. Effects of Lisinopril and Amlodipine in Combination for the Treatment of Hypertension with Pulse Wave Velocity VP Plus 1000 Meter. Am. J. Clin. Exp. Med. 2022, 10(3), 67-73. doi: 10.11648/j.ajcem.20221003.11

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AMA Style

Cao Truong Sinh, Hoang Ngoc Linh. Effects of Lisinopril and Amlodipine in Combination for the Treatment of Hypertension with Pulse Wave Velocity VP Plus 1000 Meter. Am J Clin Exp Med. 2022;10(3):67-73. doi: 10.11648/j.ajcem.20221003.11

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@article{10.11648/j.ajcem.20221003.11,
  author = {Cao Truong Sinh and Hoang Ngoc Linh},
  title = {Effects of Lisinopril and Amlodipine in Combination for the Treatment of Hypertension with Pulse Wave Velocity VP Plus 1000 Meter},
  journal = {American Journal of Clinical and Experimental Medicine},
  volume = {10},
  number = {3},
  pages = {67-73},
  doi = {10.11648/j.ajcem.20221003.11},
  url = {https://doi.org/10.11648/j.ajcem.20221003.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajcem.20221003.11},
  abstract = {Aim: The aim of this study was to evaluate the antihypertensive efficacy of lisinopril and amlodipine in combination which were measured by the pulse wave velocity meter. Research objects and Methods: 40 patients with primary hypertension, mean age 69.18 ± 10.4 years. All patients had their blood pressure, pulse wave velocity (baWPV), ankle brachial index measured by pulse wave velocity VP Plus 1000 meter before receiving the treatment. All patients were then given the Lisonorm combination pill (lisinopril 10 mg and amlodipine 5 mg) for 4 weeks. After 4 weeks, the patients was measured again with the same device (the pulse wave velocity of VP Plus 1000 meter). Results: After 4 weeks, the values of the Right arm blood pressure decreased: 26.58 ± 9.51 mmHg/ 8.6 ± 4.47 mmHg; Left arm blood pressure decreased: 26.88 ± 11.27/13.55 ± 8.15mmHg; Right ankle blood pressure decreased: 23.75 ± 11.78/10.75 ± 6.64mmHg; Left ankle blood pressure decreased: 30.33 ± 16.64/13.6 ± 9.28mmHg; The rate of patients with the target blood pressure was 72.5% (29/40 patients). Right baPWV decreased 593.65 ± 416.59 cm/s; Left baPWV decreased 585.4 ± 447.19 cm/s. Conclusion: The combination of lisinopril 10mg and amlodipine 5mg effectively had decreased the blood pressure in both extremities and pulse wave velocity, and had reduced vessel wall stiffness when it was measured by the pulse wave velocity VP Plus 1000 meter.},
 year = {2022}
}

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TY  - JOUR
T1  - Effects of Lisinopril and Amlodipine in Combination for the Treatment of Hypertension with Pulse Wave Velocity VP Plus 1000 Meter
AU  - Cao Truong Sinh
AU  - Hoang Ngoc Linh
Y1  - 2022/05/12
PY  - 2022
N1  - https://doi.org/10.11648/j.ajcem.20221003.11
DO  - 10.11648/j.ajcem.20221003.11
T2  - American Journal of Clinical and Experimental Medicine
JF  - American Journal of Clinical and Experimental Medicine
JO  - American Journal of Clinical and Experimental Medicine
SP  - 67
EP  - 73
PB  - Science Publishing Group
SN  - 2330-8133
UR  - https://doi.org/10.11648/j.ajcem.20221003.11
AB  - Aim: The aim of this study was to evaluate the antihypertensive efficacy of lisinopril and amlodipine in combination which were measured by the pulse wave velocity meter. Research objects and Methods: 40 patients with primary hypertension, mean age 69.18 ± 10.4 years. All patients had their blood pressure, pulse wave velocity (baWPV), ankle brachial index measured by pulse wave velocity VP Plus 1000 meter before receiving the treatment. All patients were then given the Lisonorm combination pill (lisinopril 10 mg and amlodipine 5 mg) for 4 weeks. After 4 weeks, the patients was measured again with the same device (the pulse wave velocity of VP Plus 1000 meter). Results: After 4 weeks, the values of the Right arm blood pressure decreased: 26.58 ± 9.51 mmHg/ 8.6 ± 4.47 mmHg; Left arm blood pressure decreased: 26.88 ± 11.27/13.55 ± 8.15mmHg; Right ankle blood pressure decreased: 23.75 ± 11.78/10.75 ± 6.64mmHg; Left ankle blood pressure decreased: 30.33 ± 16.64/13.6 ± 9.28mmHg; The rate of patients with the target blood pressure was 72.5% (29/40 patients). Right baPWV decreased 593.65 ± 416.59 cm/s; Left baPWV decreased 585.4 ± 447.19 cm/s. Conclusion: The combination of lisinopril 10mg and amlodipine 5mg effectively had decreased the blood pressure in both extremities and pulse wave velocity, and had reduced vessel wall stiffness when it was measured by the pulse wave velocity VP Plus 1000 meter.
VL  - 10
IS  - 3
ER  -

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