| Peer-Reviewed

Reconnoitring Natural Antibacterial Appraisal of Medicinal Plants Extract Against Human Pathogen Salmonella Paratyphi A and Salmonella Paratyphi B

Received: 14 June 2021    Accepted: 24 June 2021    Published: 6 July 2021
Views:       Downloads:
Abstract

Regardless of the convenience of plentiful miscellaneous collection of synthetic products and high-throughput tactics for their biological testing, natural compounds twig at a major source for antimicrobial drug development. These compounds are exclusively treasured as they have endured natural assortment over time. In this study we concentrated on Ethnobotanical efficacy of Indian medicinal plants like Ocimum sanctum, Phyllanthus emblica and Bryophyllum pinnatum for defence against bacterial human pathogen salmonella paratyphi A and salmonella paratyphi B. Phytochemical screening of these plants was executed for constituents like alkaloids, flavonoids, tannins, steroids, glycosides, carbohydrates and aminoacids. The ethanol extract of these plants exhibited good activity against the human pathogens by agar well diffusion assay method and the MIC was recorded. Average mean zone of inhibition found by these plants ranged between 4 mm to 29 mm and 4 mm to 27 mm respectively for salmonella paratyphi A and salmonella paratyphi B. These results accomplish the antimicrobial potential of the medicinal plants and hence convey upkeep for the use of them in traditional medicine.

Published in Chemical and Biomolecular Engineering (Volume 6, Issue 2)
DOI 10.11648/j.cbe.20210602.11
Page(s) 30-36
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Antimicrobial Activity, Ethnobotany, Inhibition, Human Pathogen, Medicinal Plants

References
[1] Wikaningtyas, P. and E. Y. Sukandar, The antibacterial activity of selected plants towards resistant bacteria isolated from clinical specimens. Asian Pacific Journal of Tropical Biomedicine, 2016. 6 (1): p. 16-19.
[2] Prakash, P. and N. Gupta, Therapeutic uses of Ocimum sanctum Linn (Tulsi) with a note on eugenol and its pharmacological actions: a short review. Indian journal of physiology and pharmacology, 2005. 49 (2): p. 125.
[3] Gurnani, C., et al., Conservation of medicinal plant Bryophyllum Pinnatum (LAM.) kurz by In Vitro nodal culture. International Journal of Pharmaceutical Sciences and Research, 2014. 5 (6): p. 2406.
[4] Mirunalini, S. and M. Krishnaveni, Therapeutic potential of Phyllanthus emblica (amla): the ayurvedic wonder. Journal of basic and clinical physiology and pharmacology, 2010. 21 (1): p. 93-105.
[5] Dewangan, M. K., et al., Medicinal value of curcuma cassia Roxb: an overview. Earth journals, 2014. 3 (4): p. 1-9.
[6] Sayyed, A. and M. Shah, Phytochemistry, pharmacological and traditional uses of Datura stramonium L. Rev J Pharmacogn Phytochem, 2014. 2: p. 123-5.
[7] Khan, S., et al., Medicinal and nutritional qualities of zingiber officinale, in Fruits, vegetables, and herbs. 2016, Elsevier. p. 525-550.
[8] Sharma, S., et al., Plant Growth-Promoting Rhizobacteria (PGPR): emergence and future facets in medicinal plants, in Plant-Growth-Promoting Rhizobacteria (PGPR) and Medicinal Plants. 2015, Springer. p. 109-131.
[9] Thirumurugan, K., Antimicrobial activity and phytochemical analysis of selected Indian folk medicinal plants. steroids, 2010. 1 (7).
[10] Balandrin, M. F., et al., Natural plant chemicals: sources of industrial and medicinal materials. Science, 1985. 228 (4704): p. 1154-60.
[11] Ginovyan, M., M. Petrosyan, and A. Trchounian, Antimicrobial activity of some plant materials used in Armenian traditional medicine. BMC complementary and alternative medicine, 2017. 17 (1): p. 50.
[12] Bzdil, J., O. Holy, and J. Toporcak, Salmonella enterica subspecies enterica serovar Paratyphi B as a disease-causing agent in reptiles in the Czech Republic. Veterinární medicína, 2017. 62 (7): p. 410-415.
[13] Bhan, M. K., R. Bahl, and S. Bhatnagar, Typhoid and paratyphoid fever. Lancet, 2005. 366 (9487): p. 749-62.
[14] Ochiai, R. L., et al., Salmonella paratyphi A rates, Asia. Emerg Infect Dis, 2005. 11 (11): p. 1764-6.
[15] Panezai, M., et al., Isolation and Identification of Salmonella paratyphi from Enteric Fever Patients at Different Hospitals of Quetta City. Pakistan journal of biological sciences: PJBS, 2018. 21 (9): p. 469-474.
[16] Girard, M. P., et al., A review of vaccine research and development: human enteric infections. Vaccine, 2006. 24 (15): p. 2732-50.
[17] Ajiboye, A., S. Sadiq, and M. Adedayo, Antimicrobial activity and phytochemical screening of Adansonia digitata stem bark extract on some clinical isolates. Ife Journal of Science, 2020. 22 (2): p. 035-044.
[18] Sumathi, P. and A. Parvathi, Antimicrobial activity of some traditional medicinal plants. Journal of Medicinal plants research, 2010. 4 (4): p. 316-321.
[19] Orji, J., et al., Antibacterial activities of crude leaf and bark extracts of “icheku” Dialium guineense on bacterial isolates from bronchitis patients. IOSR J Pharm Biol Sci, 2012. 1: p. 21-25.
[20] Larson, E. C., et al., Traditional Preparations and Methanol Extracts of Medicinal Plants from Papua New Guinea Exhibit Similar Cytochrome P450 Inhibition. Evid Based Complement Alternat Med, 2016. 2016: p. 7869710.
[21] Egwaikhide, P. and C. Gimba, Analysis of the phytochemical content and anti-microbial activity of Plectranthus glandulosis whole plant. Middle-East Journal of Scientific Research, 2007. 2 (3-4): p. 135-138.
[22] McFarland, J., The nephelometer: an instrument for estimating the number of bacteria in suspensions used for calculating the opsonic index and for vaccines. Journal of the American Medical Association, 1907. 49 (14): p. 1176-1178.
[23] Perez, C., Antibiotic assay by agar-well diffusion method. Acta Biol Med Exp, 1990. 15: p. 113-115.
[24] Ahmad, I. and A. Z. Beg, Antimicrobial and phytochemical studies on 45 Indian medicinal plants against multi-drug resistant human pathogens. J Ethnopharmacol, 2001. 74 (2): p. 113-23.
[25] Das, K., R. Tiwari, and D. Shrivastava, Techniques for evaluation of medicinal plant products as antimicrobial agents: current methods and future trends. Journal of medicinal plants research, 2010. 4 (2): p. 104-111.
[26] Srinivasan, D., et al., Antimicrobial activity of certain Indian medicinal plants used in folkloric medicine. Journal of ethnopharmacology, 2001. 74 (3): p. 217-220.
[27] Pandey, M., S. Rastogi, and A. Rawat, Indian traditional ayurvedic system of medicine and nutritional supplementation. Evidence-Based Complementary and Alternative Medicine, 2013. 2013.
[28] Akinyemi, K., et al., Screening of some medicinal plants used in south-west Nigerian traditional medicine for anti-Salmonella typhi activity. Journal of Herbal Pharmacotherapy, 2005. 5 (1): p. 45-60.
[29] Gowri, S. S. and K. Vasantha, Phytochemical screening and antibacterial activity of Syzygium cumini (L.) (Myrtaceae) leaves extracts. Int J Pharm Tech Res, 2010. 2 (2): p. 1569-1573.
Cite This Article
  • APA Style

    Janki Ruparelia, Aniruddh Rabari, Nishra Joshi, Asha Dhediya, Jigisha Halpati, et al. (2021). Reconnoitring Natural Antibacterial Appraisal of Medicinal Plants Extract Against Human Pathogen Salmonella Paratyphi A and Salmonella Paratyphi B. Chemical and Biomolecular Engineering, 6(2), 30-36. https://doi.org/10.11648/j.cbe.20210602.11

    Copy | Download

    ACS Style

    Janki Ruparelia; Aniruddh Rabari; Nishra Joshi; Asha Dhediya; Jigisha Halpati, et al. Reconnoitring Natural Antibacterial Appraisal of Medicinal Plants Extract Against Human Pathogen Salmonella Paratyphi A and Salmonella Paratyphi B. Chem. Biomol. Eng. 2021, 6(2), 30-36. doi: 10.11648/j.cbe.20210602.11

    Copy | Download

    AMA Style

    Janki Ruparelia, Aniruddh Rabari, Nishra Joshi, Asha Dhediya, Jigisha Halpati, et al. Reconnoitring Natural Antibacterial Appraisal of Medicinal Plants Extract Against Human Pathogen Salmonella Paratyphi A and Salmonella Paratyphi B. Chem Biomol Eng. 2021;6(2):30-36. doi: 10.11648/j.cbe.20210602.11

    Copy | Download

  • @article{10.11648/j.cbe.20210602.11,
      author = {Janki Ruparelia and Aniruddh Rabari and Nishra Joshi and Asha Dhediya and Jigisha Halpati and Ankita Patel and Chaitanya Kumar Jha},
      title = {Reconnoitring Natural Antibacterial Appraisal of Medicinal Plants Extract Against Human Pathogen Salmonella Paratyphi A and Salmonella Paratyphi B},
      journal = {Chemical and Biomolecular Engineering},
      volume = {6},
      number = {2},
      pages = {30-36},
      doi = {10.11648/j.cbe.20210602.11},
      url = {https://doi.org/10.11648/j.cbe.20210602.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cbe.20210602.11},
      abstract = {Regardless of the convenience of plentiful miscellaneous collection of synthetic products and high-throughput tactics for their biological testing, natural compounds twig at a major source for antimicrobial drug development. These compounds are exclusively treasured as they have endured natural assortment over time. In this study we concentrated on Ethnobotanical efficacy of Indian medicinal plants like Ocimum sanctum, Phyllanthus emblica and Bryophyllum pinnatum for defence against bacterial human pathogen salmonella paratyphi A and salmonella paratyphi B. Phytochemical screening of these plants was executed for constituents like alkaloids, flavonoids, tannins, steroids, glycosides, carbohydrates and aminoacids. The ethanol extract of these plants exhibited good activity against the human pathogens by agar well diffusion assay method and the MIC was recorded. Average mean zone of inhibition found by these plants ranged between 4 mm to 29 mm and 4 mm to 27 mm respectively for salmonella paratyphi A and salmonella paratyphi B. These results accomplish the antimicrobial potential of the medicinal plants and hence convey upkeep for the use of them in traditional medicine.},
     year = {2021}
    }
    

    Copy | Download

  • TY  - JOUR
    T1  - Reconnoitring Natural Antibacterial Appraisal of Medicinal Plants Extract Against Human Pathogen Salmonella Paratyphi A and Salmonella Paratyphi B
    AU  - Janki Ruparelia
    AU  - Aniruddh Rabari
    AU  - Nishra Joshi
    AU  - Asha Dhediya
    AU  - Jigisha Halpati
    AU  - Ankita Patel
    AU  - Chaitanya Kumar Jha
    Y1  - 2021/07/06
    PY  - 2021
    N1  - https://doi.org/10.11648/j.cbe.20210602.11
    DO  - 10.11648/j.cbe.20210602.11
    T2  - Chemical and Biomolecular Engineering
    JF  - Chemical and Biomolecular Engineering
    JO  - Chemical and Biomolecular Engineering
    SP  - 30
    EP  - 36
    PB  - Science Publishing Group
    SN  - 2578-8884
    UR  - https://doi.org/10.11648/j.cbe.20210602.11
    AB  - Regardless of the convenience of plentiful miscellaneous collection of synthetic products and high-throughput tactics for their biological testing, natural compounds twig at a major source for antimicrobial drug development. These compounds are exclusively treasured as they have endured natural assortment over time. In this study we concentrated on Ethnobotanical efficacy of Indian medicinal plants like Ocimum sanctum, Phyllanthus emblica and Bryophyllum pinnatum for defence against bacterial human pathogen salmonella paratyphi A and salmonella paratyphi B. Phytochemical screening of these plants was executed for constituents like alkaloids, flavonoids, tannins, steroids, glycosides, carbohydrates and aminoacids. The ethanol extract of these plants exhibited good activity against the human pathogens by agar well diffusion assay method and the MIC was recorded. Average mean zone of inhibition found by these plants ranged between 4 mm to 29 mm and 4 mm to 27 mm respectively for salmonella paratyphi A and salmonella paratyphi B. These results accomplish the antimicrobial potential of the medicinal plants and hence convey upkeep for the use of them in traditional medicine.
    VL  - 6
    IS  - 2
    ER  - 

    Copy | Download

Author Information
  • Microbiology Department, Gujarat Arts and Science College, Ellisbridge, Ahmedabad, India

  • Microbiology Department, Gujarat Arts and Science College, Ellisbridge, Ahmedabad, India

  • Microbiology Department, Gujarat Arts and Science College, Ellisbridge, Ahmedabad, India

  • Microbiology Department, Gujarat Arts and Science College, Ellisbridge, Ahmedabad, India

  • Microbiology Department, Gujarat Arts and Science College, Ellisbridge, Ahmedabad, India

  • Microbiology Department, Gujarat Arts and Science College, Ellisbridge, Ahmedabad, India

  • Microbiology Department, Gujarat Arts and Science College, Ellisbridge, Ahmedabad, India

  • Sections