Multifocal Atherosclerosis: The Clinical Course and Surgical Treatment of Combined Atherosclerotic Lesions of the Carotid and Main Arteries of the Lower Extremities

Kordzakhia George; Yanushko Vyacheslav; Klimchuk Ivan

doi:doi:10.11648/j.ccr.20210501.17

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Multifocal Atherosclerosis: The Clinical Course and Surgical Treatment of Combined Atherosclerotic Lesions of the Carotid and Main Arteries of the Lower Extremities

Kordzakhia George, Yanushko Vyacheslav, Klimchuk Ivan

Published in Cardiology and Cardiovascular Research (Volume 5, Issue 1)

Received: 6 January 2021 Accepted: 9 February 2021 Published: 23 February 2021

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Abstract

Cardiovascular disease (CVD) has been for many years the major cause of deaths in the World. In Europe, despite recent decreases in mortality rates in many countries, CVD is still responsible for about half (46%) of all deaths. Atherosclerosis is a chronic progressive disease which can affect any vascular bed (coronary, cerebrovascular, visceral, peripheral arterial) as a single disease but can also occurs in more than one territory as polyvascular disease. Presence of atherosclerotic disease in one vascular bed frequently indicates an increased risk for its presence in another. The prevalence of polyvascular disease varies from 6% to 71%, depend on the population in whom the study was performed as well as on the study design. Polyvascular disease patients have the worse higher risk profile and worse prognosis than patients with disease in single arterial territory and an improvement in detection and consequent treatment of these patients have been claimed as necessary. The most difficult choice of treatment tactics is the group of patients with peripheral artery disease and concomitant atherosclerotic lesions of other arterial beds. According to a population study conducted in the United States among 3.6 million healthy volunteers based on ultrasound screening, the detection of two or more arterial regions increases with age from 0.04% at 40-50 years, to 3.6% at 80-90 years. At the same time, the results of treatment and prognosis in these patients are much worse than in those with isolated lesions of only one vascular beds.

Published in	Cardiology and Cardiovascular Research (Volume 5, Issue 1)
DOI	10.11648/j.ccr.20210501.17
Page(s)	36-40
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Multifocal Atherosclerosis, Ischemic Heart Disease, Carotid Stenosis, Claudication, Carotid Artery Stenosis

References

[1]	Smoking, diabetes, and blood cholesterol differ in their associations with subclinical atherosclerosis: the Multiethnic Study of Atherosclerosis (MESA) // Atherosclerosis. - 2006. - Vol. 186, № 2. - P. 441-447.
[2]	Diehm C, Schuster A, Allenberg JR, Darius H, Haberl R, Lange S, Pittrow D, von Stritzky B, Tepohl G, Trampisch HJ. High prevalence of peripheral arterial disease and co-morbidity in 6880 primary care patients: cross-sectional study. Atherosclerosis 2004; 172: 95–105.
[3]	Sigvant B, Wiberg-Hedman K, Bergqvist D, Rolandsson O, Andersson B, Persson E, Wahlberg E. A population-based study of peripheral arterial disease prevalence with special focus on critical limb ischemia and sex differences. J VascSurg 2007; 45: 1185–1191.
[4]	Truelsen B, Piechowski-Jozwiak T, Bonita R, Mathersa C, Bogousslavsky J, Boysen G. Stroke incidence and prevalence in Europe. EurNeurol 2006; 13: 581e98.3.
[5]	http://www.government.by/upload/docs/filecdf0f8a76b95e004.PDF. The state program "People’s Health and Demographic Security of the Republic of Belarus" on 2016-2020 gody [Elektronnyjresurs] / Sovet Ministrov Respubliki Belarus'.
[6]	Yanushko V. A., Klimchuk I. P., Popel G. A., Ladygin P. A., Shestak N. G. Surgical revascularization of the lower extremities in patients with ischemic diabetic foot syndrome. No. 2 (February) 2013 / "Healthcare"/.
[7]	Hirsch AT, Haskal ZJ, Hertzer NR, et al ACC/AHA 2005 Guidelines for the Management of Patients With Peripheral Arterial Disease (Lower Extremity, Renal, Mesenteric, and Abdominal Aortic): A Collaborative Report from the American Association for Vascular Surgery/Society for Vascular Surgery, Society for Cardiovascular Angiography and Interventions, Society for Vascular Medicine and Biology, Society of Interventional Radiology, and the ACC/AHA Task Force on Practice Guidelines (Writing Committee to Develop Guidelines for the Management of Patients With Peripheral Arterial Disease). J Am CollCardiol. 2006; 47: e1-e192.
[8]	Screening of the internal carotid arteries in patients with peripheral vascular disease by colour-flow duplex scanning. Klop RB, Eikelboom BC, Taks AC Eur J Vasc Surg. 1991 Feb; 5 (1): 41-5.
[9]	Surgery of the aorta and its branches. V. A. YAnushko [i dr.]; il. vypolneny P. M. Lozhko. - Moskva: Medicinskayaliteratura, 2013. - 205 s.
[10]	Yanushko V. A. ONE-STAGE SURGICAL CORRECTION IN CASE OF COMBINED LESIONS OF THE CAROTID AND CORONARY ARTERIES. Proceedings of the National Academy of Sciences of Belarus, Medical series. 2018; 15 (3): 354-362.
[11]	Aboyans V, Ricco JB, Bartelink MEL, Björck M, Brodmann M, Cohnert T, Collet JP, Czerny M, De Carlo M, Debus S, et al.; ESC Scientific Document Group. 2017 ESC guidelines on the diagnosis and treatment of peripheral arterial diseases, in collaboration with the European Society for Vascular Surgery (ESVS): document covering atherosclerotic disease of extracranial carotid and vertebral, mesenteric, renal, upper and lower extremity arteriesEndorsed by: the European Stroke Organization (ESO) The Task Force for the Diagnosis and Treatment of Peripheral Arterial Diseases of the European Society of Cardiology (ESC) and of the European Society for Vascular Surgery (ESVS). Eur Heart J. 2018; 39: 763–816. doi: 10.1093/eurheartj/ehx095.
[12]	Gerhard-Herman MD, Gornik HL, Barrett C, Barshes NR, Corriere MA, Drachman DE, Fleisher LA, Fowkes FG, Hamburg NM, Kinlay S, et al.. 2016 AHA/ACC guideline on the management of patients with lower extremity peripheral artery disease: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. Circulation. 2017; 135: e726–e779. doi: 10.1161/CIR.0000000000000471.
[13]	Aday AW, Lawler PR, Cook NR, Ridker PM, Mora S, Pradhan AD. Lipoprotein particle profiles, standard lipids, and peripheral artery disease incidence. Circulation. 2018; 138: 2330–2341. doi: 10.1161/CIRCULATIONAHA.118.035432.
[14]	Anand SS, Bosch J, Eikelboom JW, Connolly SJ, Diaz R, Widimsky P, Aboyans V, Alings M, Kakkar AK, Keltai K, et al.; COMPASS Investigators. Rivaroxaban with or without aspirin in patients with stable peripheral or carotid artery disease: an international, randomised, double-blind, placebo-controlled trial. Lancet. 2018; 391: 219–229. doi: 10.1016/S0140-6736(17)32409-1.
[15]	Bonaca MP, Gutierrez JA, Cannon C, Giugliano R, Blazing M, Park JG, White J, Tershakovec A, Braunwald E. Polyvascular disease, type 2 diabetes, and long-term vascular risk: a secondary analysis of the IMPROVE-IT trial. Lancet Diabetes Endocrinol. 2018; 6: 934–943. doi: 10.1016/S2213-8587(18)30290-0.

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APA Style

Kordzakhia George, Yanushko Vyacheslav, Klimchuk Ivan. (2021). Multifocal Atherosclerosis: The Clinical Course and Surgical Treatment of Combined Atherosclerotic Lesions of the Carotid and Main Arteries of the Lower Extremities. Cardiology and Cardiovascular Research, 5(1), 36-40. https://doi.org/10.11648/j.ccr.20210501.17

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ACS Style

Kordzakhia George; Yanushko Vyacheslav; Klimchuk Ivan. Multifocal Atherosclerosis: The Clinical Course and Surgical Treatment of Combined Atherosclerotic Lesions of the Carotid and Main Arteries of the Lower Extremities. Cardiol. Cardiovasc. Res. 2021, 5(1), 36-40. doi: 10.11648/j.ccr.20210501.17

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AMA Style

Kordzakhia George, Yanushko Vyacheslav, Klimchuk Ivan. Multifocal Atherosclerosis: The Clinical Course and Surgical Treatment of Combined Atherosclerotic Lesions of the Carotid and Main Arteries of the Lower Extremities. Cardiol Cardiovasc Res. 2021;5(1):36-40. doi: 10.11648/j.ccr.20210501.17

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@article{10.11648/j.ccr.20210501.17,
  author = {Kordzakhia George and Yanushko Vyacheslav and Klimchuk Ivan},
  title = {Multifocal Atherosclerosis: The Clinical Course and Surgical Treatment of Combined Atherosclerotic Lesions of the Carotid and Main Arteries of the Lower Extremities},
  journal = {Cardiology and Cardiovascular Research},
  volume = {5},
  number = {1},
  pages = {36-40},
  doi = {10.11648/j.ccr.20210501.17},
  url = {https://doi.org/10.11648/j.ccr.20210501.17},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ccr.20210501.17},
  abstract = {Cardiovascular disease (CVD) has been for many years the major cause of deaths in the World. In Europe, despite recent decreases in mortality rates in many countries, CVD is still responsible for about half (46%) of all deaths. Atherosclerosis is a chronic progressive disease which can affect any vascular bed (coronary, cerebrovascular, visceral, peripheral arterial) as a single disease but can also occurs in more than one territory as polyvascular disease. Presence of atherosclerotic disease in one vascular bed frequently indicates an increased risk for its presence in another. The prevalence of polyvascular disease varies from 6% to 71%, depend on the population in whom the study was performed as well as on the study design. Polyvascular disease patients have the worse higher risk profile and worse prognosis than patients with disease in single arterial territory and an improvement in detection and consequent treatment of these patients have been claimed as necessary. The most difficult choice of treatment tactics is the group of patients with peripheral artery disease and concomitant atherosclerotic lesions of other arterial beds. According to a population study conducted in the United States among 3.6 million healthy volunteers based on ultrasound screening, the detection of two or more arterial regions increases with age from 0.04% at 40-50 years, to 3.6% at 80-90 years. At the same time, the results of treatment and prognosis in these patients are much worse than in those with isolated lesions of only one vascular beds.},
 year = {2021}
}

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TY  - JOUR
T1  - Multifocal Atherosclerosis: The Clinical Course and Surgical Treatment of Combined Atherosclerotic Lesions of the Carotid and Main Arteries of the Lower Extremities
AU  - Kordzakhia George
AU  - Yanushko Vyacheslav
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T2  - Cardiology and Cardiovascular Research
JF  - Cardiology and Cardiovascular Research
JO  - Cardiology and Cardiovascular Research
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AB  - Cardiovascular disease (CVD) has been for many years the major cause of deaths in the World. In Europe, despite recent decreases in mortality rates in many countries, CVD is still responsible for about half (46%) of all deaths. Atherosclerosis is a chronic progressive disease which can affect any vascular bed (coronary, cerebrovascular, visceral, peripheral arterial) as a single disease but can also occurs in more than one territory as polyvascular disease. Presence of atherosclerotic disease in one vascular bed frequently indicates an increased risk for its presence in another. The prevalence of polyvascular disease varies from 6% to 71%, depend on the population in whom the study was performed as well as on the study design. Polyvascular disease patients have the worse higher risk profile and worse prognosis than patients with disease in single arterial territory and an improvement in detection and consequent treatment of these patients have been claimed as necessary. The most difficult choice of treatment tactics is the group of patients with peripheral artery disease and concomitant atherosclerotic lesions of other arterial beds. According to a population study conducted in the United States among 3.6 million healthy volunteers based on ultrasound screening, the detection of two or more arterial regions increases with age from 0.04% at 40-50 years, to 3.6% at 80-90 years. At the same time, the results of treatment and prognosis in these patients are much worse than in those with isolated lesions of only one vascular beds.
VL  - 5
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Author Information

Kordzakhia George

Department of Vascular Surgery, City Clinical Hospital Named After Nikolay Evseevich Savchenko, Minsk, Belarus
Yanushko Vyacheslav

Laboratory of Vascular Surgery, Republican Scientific and Practical Centre ?Cardiology?, Minsk, Belarus
Klimchuk Ivan

Department of Vascular Surgery, City Clinical Hospital Named After Nikolay Evseevich Savchenko, Minsk, Belarus

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APA Style

Kordzakhia George, Yanushko Vyacheslav, Klimchuk Ivan. (2021). Multifocal Atherosclerosis: The Clinical Course and Surgical Treatment of Combined Atherosclerotic Lesions of the Carotid and Main Arteries of the Lower Extremities. Cardiology and Cardiovascular Research, 5(1), 36-40. https://doi.org/10.11648/j.ccr.20210501.17

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ACS Style

Kordzakhia George; Yanushko Vyacheslav; Klimchuk Ivan. Multifocal Atherosclerosis: The Clinical Course and Surgical Treatment of Combined Atherosclerotic Lesions of the Carotid and Main Arteries of the Lower Extremities. Cardiol. Cardiovasc. Res. 2021, 5(1), 36-40. doi: 10.11648/j.ccr.20210501.17

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AMA Style

Kordzakhia George, Yanushko Vyacheslav, Klimchuk Ivan. Multifocal Atherosclerosis: The Clinical Course and Surgical Treatment of Combined Atherosclerotic Lesions of the Carotid and Main Arteries of the Lower Extremities. Cardiol Cardiovasc Res. 2021;5(1):36-40. doi: 10.11648/j.ccr.20210501.17

Copy | Download

@article{10.11648/j.ccr.20210501.17,
  author = {Kordzakhia George and Yanushko Vyacheslav and Klimchuk Ivan},
  title = {Multifocal Atherosclerosis: The Clinical Course and Surgical Treatment of Combined Atherosclerotic Lesions of the Carotid and Main Arteries of the Lower Extremities},
  journal = {Cardiology and Cardiovascular Research},
  volume = {5},
  number = {1},
  pages = {36-40},
  doi = {10.11648/j.ccr.20210501.17},
  url = {https://doi.org/10.11648/j.ccr.20210501.17},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ccr.20210501.17},
  abstract = {Cardiovascular disease (CVD) has been for many years the major cause of deaths in the World. In Europe, despite recent decreases in mortality rates in many countries, CVD is still responsible for about half (46%) of all deaths. Atherosclerosis is a chronic progressive disease which can affect any vascular bed (coronary, cerebrovascular, visceral, peripheral arterial) as a single disease but can also occurs in more than one territory as polyvascular disease. Presence of atherosclerotic disease in one vascular bed frequently indicates an increased risk for its presence in another. The prevalence of polyvascular disease varies from 6% to 71%, depend on the population in whom the study was performed as well as on the study design. Polyvascular disease patients have the worse higher risk profile and worse prognosis than patients with disease in single arterial territory and an improvement in detection and consequent treatment of these patients have been claimed as necessary. The most difficult choice of treatment tactics is the group of patients with peripheral artery disease and concomitant atherosclerotic lesions of other arterial beds. According to a population study conducted in the United States among 3.6 million healthy volunteers based on ultrasound screening, the detection of two or more arterial regions increases with age from 0.04% at 40-50 years, to 3.6% at 80-90 years. At the same time, the results of treatment and prognosis in these patients are much worse than in those with isolated lesions of only one vascular beds.},
 year = {2021}
}

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TY  - JOUR
T1  - Multifocal Atherosclerosis: The Clinical Course and Surgical Treatment of Combined Atherosclerotic Lesions of the Carotid and Main Arteries of the Lower Extremities
AU  - Kordzakhia George
AU  - Yanushko Vyacheslav
AU  - Klimchuk Ivan
Y1  - 2021/02/23
PY  - 2021
N1  - https://doi.org/10.11648/j.ccr.20210501.17
DO  - 10.11648/j.ccr.20210501.17
T2  - Cardiology and Cardiovascular Research
JF  - Cardiology and Cardiovascular Research
JO  - Cardiology and Cardiovascular Research
SP  - 36
EP  - 40
PB  - Science Publishing Group
SN  - 2578-8914
UR  - https://doi.org/10.11648/j.ccr.20210501.17
AB  - Cardiovascular disease (CVD) has been for many years the major cause of deaths in the World. In Europe, despite recent decreases in mortality rates in many countries, CVD is still responsible for about half (46%) of all deaths. Atherosclerosis is a chronic progressive disease which can affect any vascular bed (coronary, cerebrovascular, visceral, peripheral arterial) as a single disease but can also occurs in more than one territory as polyvascular disease. Presence of atherosclerotic disease in one vascular bed frequently indicates an increased risk for its presence in another. The prevalence of polyvascular disease varies from 6% to 71%, depend on the population in whom the study was performed as well as on the study design. Polyvascular disease patients have the worse higher risk profile and worse prognosis than patients with disease in single arterial territory and an improvement in detection and consequent treatment of these patients have been claimed as necessary. The most difficult choice of treatment tactics is the group of patients with peripheral artery disease and concomitant atherosclerotic lesions of other arterial beds. According to a population study conducted in the United States among 3.6 million healthy volunteers based on ultrasound screening, the detection of two or more arterial regions increases with age from 0.04% at 40-50 years, to 3.6% at 80-90 years. At the same time, the results of treatment and prognosis in these patients are much worse than in those with isolated lesions of only one vascular beds.
VL  - 5
IS  - 1
ER  -

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