Research Article | | Peer-Reviewed

The Impact of Common Comorbidities on the Cardiopulmonary Rehabilitation Outcomes and Cost of Care for Post-CABG Surgery Patients

Received: 18 September 2023    Accepted: 10 October 2023    Published: 28 October 2023
Views:       Downloads:
Abstract

Background: The incidence of coronary Heart Disease (CHD) has increased globally, including in Saudi Arabia. Consequently, the use of coronary artery bypass graft (CABG) surgery, one of the most valuable solutions, has also increased. Common comorbidities (CMs) such as diabetes mellitus (DM), hypertension (HTN), peripheral vascular disease (PVD), chronic obstructive pulmonary disease (COPD), peptic ulcer disease, dialysis-dependent renal failure, and obesity have been reported to adversely affect rehabilitation outcomes, increase hospital length of stay (LOS), and increase the cost of care for post-CABG surgery patients. Despite these facts, no previous studies have assessed the effect of comorbidities on Cardiac Rehabilitation outcomes, cost of care, and length of hospital stay in post-CABG surgery patients in the Saudi Population. Objective: To assess the effect of cardiac comorbidities on the outcomes of CR intervention in CABG patients and examine how these comorbidities affect the length of stay in the intensive care unit (ICU) and hospital, as well as the cost of care. Methods: A retrospective cohort study was conducted to follow-up post-CABG patients over two years, from 2020 to 2022. A total of 62 male and female patients who met the inclusion criteria were included in this study. The subjects were divided into two groups based on the CM size. Group I consisted of patients with (> 4 CMs), whereas Group II consisted of patients with (<3 CMs). Results: Group I had a higher mean score of comorbidities (CMs) at 5.09 ± 2.43, which resulted in longer stays in the ICU at 4.34 + 2.24 and in the hospital at 9.16 + 4.63 compared to Group II at 3.43 ± 1.48 and 7.2 ± 1.47, respectively. Group II had higher total cost of care. Conclusions: This study found that patients with multiple comorbidities such as DM, HTN, and dyslipidemia had longer hospital and ICU stays and higher care costs.

Published in Cardiology and Cardiovascular Research (Volume 7, Issue 4)
DOI 10.11648/j.ccr.20230704.12
Page(s) 75-81
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

CABG, Cardiac Rehabilitation, Comorbidity, Length of Stay, Cost of Care

References
[1] World Health Organization (WHO)., 2015. Mortality Database. Geneva, Switzerland: World Health Organization, Department of Health Statistics and Information Systems, http://www.who.int/healthinfo/mortality_data/en/ [accessed 23 Feb 2023).
[2] Al-Jefree, N. & Ahmed, F., 2015. Prevalence of cardiovascular disease and associated risk factors among adult population in the Gulf region: a systematic review. Advances in Public Health, 2015, pp. 1-23.
[3] Mabry, R. M., Reeves, M. M., Eakin, E. G. & Owen, N., Gender differences in prevalence of the metabolic syndrome in Gulf Cooperation Council Countries: a systematic review. Diabetic Medicine. 2010; 27 (5), pp. 593-597.
[4] Gaziano, T. A., Bitton, A., Anand, S., Abrahams-gessel, S. et al. Growing epidemic of coronary heart disease in low-and middle-income countries. Current Problems in Cardiology. 2010; 35 (2), pp. 72-115.
[5] Ndahimana, D., & Kim, E. K. Measurement Methods for Physical Activity and Energy Expenditure: a Review. Clinical Nutrition Research. 2017 6 (2), 68–80.
[6] Glei, D., Mesle, F., & Vallin, J., 2010. Diverging trends in life expectancy at age 50: A look at causes of death. In E. M. Crimmins, S. H. Preston & B. Cohen (Eds.), International differences in mortality at older ages: Dimensions and sources. Washington, DC: The National Academies Press.
[7] Hatmi, Z. N., Tahvildari, S., Motlag, A. G. & Kashani, A. S. Prevalence of coronary artery disease risk factors in Iran: a population-based survey, BMC, Cardiovasc Disord. 2007 7, p. 32.
[8] Al-Nozha, M. M., Al-Maatouq, M. A., Al-Mazrou, Y. Y. & Al-Harthi, S. S. Diabetes Mellitus in Saudi Arabia. Saudi Medical Journal. 2004; 25 (11): pp. 1603-1610.
[9] World Health Organization (WHO), 2011a. Non-communicable Diseases Country Profiles. 2011; Geneva: World Health Organization. http://www.WHO global report | ICCP Portal (iccp-portal.org). (Accessed 13 March 2022).
[10] Ibrahim, A. G. E., Cheng, K. & Marbán, E. Exosomes as critical agents of cardiac regeneration triggered by cell therapy. Stem Cell Reports. 2014; 2 (5), pp. 606-619.
[11] Motlagh, B., O'Donnell, M. & Yusuf, S. Prevalence of cardiovascular risk factors in the Middle East: a systematic review, European Journal of Cardiovascular Prevention and Rehabilitation. 2009; 16 (3), pp. 268–280.
[12] Singh, S. J., Puhan, M. A., Andrianopoulos, V., et al. An official systematic review of the European Respiratory Society/American Thoracic Society, measurement properties of field walking tests in chronic respiratory disease, Eur. Respir J. 2014; 44, pp. 1447–1478.
[13] Osman, A. M., Alsultan, M. S. & Al-Mutairi, M. A. The burden of ischemic heart disease at a major cardiac center in Central Saudi Arabia. Saudi Medical Journal. 2011; 32 (12), pp. 1279-1283.
[14] Al-Reshidan, M., Albabtain, M., Obied, H., Alassal, M. et al. Does Coronary Endarterectomy Increase Early Mortality and Morbidity Compared with Coronary Artery Bypass Surgery Alone-Single Centre Experience? International Journal of Clinical Medicine. 2014; 5 (05), pp. 197-205.
[15] Hussain, I., Ghaffar, A., Shahbaz, A., Sami, W. et al. In-hospital outcome of participants undergoing coronary endarterectomy: comparison between off-pump vs on-pump CABG. Journal Ayub Medical College Abottabad. 2008; 20, pp. 31-37.
[16] Lee, G. Patients reported health-related quality of life five years post coronary artery bypass graft surgery: a methodological study. European Journal of Cardiovascular Nursing, 2008a 7 (1): 67 72.
[17] Caine, N., Sharples, L. and Wallwork, J. Prospective study of quality of life before and after coronary artery bypass grafting: outcome at five years. Heart. 1999; 81 (4): 347 351.
[18] Bergeron, E., Lavoie, A., Moore L., Clas, D., Rossignol, M. Comorbidity and age are both independent predictors of length of hospitalization in trauma patients. Can J Surg. 2005; Oct; 48 (5): 361-6.
[19] Klabunde CN, Harlan LC, Warren JL. Data sources for measuring comorbidity: a comparison of hospital records and Medicare claims for cancer patients. Med Care. 2006; 44 (10): 921–8.
[20] Librero J, Peiró S, Ordiñana R. Chronic comorbidity and outcomes of hospital care: length of stay, mortality, and readmission at 30 and 365 days. J Clin Epidemiol. 1999 Mar; 52 (3): 171-9. doi: 10.1016/s0895-4356(98)00160-7.
[21] King Faisal Specialist Hospital and Research Centre, Open Data (KFSH&RC- database, 2015) [online]. Available at: https://www.kfshrc.edu.sa/en/home/opendata. [Viewed: 14/04/2023].
[22] American Association of Cardiovascular and Pulmonary Rehabilitation (AACVPR) Guidelines for Cardiac Rehabilitation and Secondary Prevention Programs. Champaign, IL: Human Kinetics, 2004.
[23] British Association for Cardiovascular Prevention and Rehabilitation Exercise Professionals Group (EPG) (2019) Position Statement 2019 (version three): Essential competences and minimum qualifications required to lead the supervised exercise component in (early) core cardiac rehabilitation. Available at https://www.bacpr.org
[24] Charlson, M., Pompei, P., Ales, M. L., & Mackenzie C. R. A new method of classifying comorbidity in longitudinal studies: Development and validation. J Chronic Dis. 1987; 40, 373-393.
[25] Charlson, M., Szatrowski, T. P., Peterson, J., & Gold, J. Validation of a Combined Comorbidity Index. Journal of Clinical Epidemiology. 1994; 47 (11), 1245-1251.
[26] Takroni, M. A., Albarrati, A., Akomolafe, T., Al Enazy, M. The Effect of Early Mobilization on ICU and Hospital Length of Stay and Its Impact on the Cost of Care in Post-Open Heart Surgery Patients: A Randomized Control Trial (RCT). J Heart Health. 2020; 7 (1): dx.doi.org/10.16966/2379-769X.157.
[27] Deyo, R. A., Cherkin, D. C., Ciol, M. A. Adapting a clinical comorbidity index for use with ICD-9-CM administrative databases. Journal of Clinical Epidemiology. 1992; 45 (6): 613-619.
[28] Moore, B. J., White, S., Washington R, Coenen N, Elixhauser A. Identifying increased risk of readmission and in-hospital mortality using hospital administrative data: the AHRQ Elixhauser Comorbidity Index. Medical Care. 2017; 55 (7): 698–705.
[29] Yang, Y., Wang, L., Liu. J., et al. Obesity or increased body mass index and the risk of severe outcomes in patients with COVID-19: A protocol for systematic review and meta-analysis. Medicine (Baltimore). 2022; 101: e28499.
[30] Preston, S. H., Vierboom, Y. C., Stokes A. The role of obesity in exceptionally slow US mortality improvement. Proceedings of the National Academy of Sciences of the United States of America. 2018; 115: 957–61.
[31] Silveira, E. A. D., Vieira, L. L., Jardim, T. V., Souza JD. Obesity and its Association with Food Consumption, Diabetes Mellitus, and Acute Myocardial Infarction in the Elderly. Arquivos Brasileiros de Cardiologia. 2016; 107: 509–17.
[32] Frasca, D., Blomberg, B. B., Paganelli, R. Aging, Obesity, and Inflammatory Age-Related Diseases. Frontiers in Immunology. 2017; 8: 1745.
[33] Gu, Z., Li, D., He, H., et al. Body mass index, waist circumference, and waist-to-height ratio for prediction of multiple metabolic risk factors in Chinese elderly population. Scientific Reports. 2018; 8: 385.
[34] Agency for Healthcare Research and Quality. Elixhauser Comorbidity Software Refined for ICD-10-CM. Healthcare Cost and Utilization Project (HCUP). October 2021. www.hcupus.ahrq.gov/toolssoftware/comorbidityicd10/comorbidity_icd10.jsp. (Accessed June 30, 2023).
[35] Hamza, A., Shah, N. N, Azad AM, Ghanshyam OS, Khan Z. Impact of age, gender and comorbidities affecting the severity of COVID-19 infection in Kashmir. J Family Med Prim Care. 2022; 11 (4): 1519-1524.
[36] Stedman, M., Lunt, M., Davies, M., Livingston, M., Duff, C., Fryer, A., Anderson, S. G.; Gadsby, R.; Gibson, M.; Rayman, G.; et al. Cost of hospital treatment of type 1 diabetes (T1DM) and type 2 diabetes (T2DM) compared to the non-diabetes population: A detailed economic evaluation. BMJ Open. 2020; 10, e033231.
[37] Mao, X., Liang, C., Niu, H., Dong, F., Huang, K., Chen, Y., Huang, K., Zhan, Q., Zhang, Y., Huang. Y., Yang, T., Wang, C. Outcomes associated with comorbid diabetes among patients with COPD exacerbation: findings from the ACURE registry. Respir Res. 2021; 22 (1): 7.
[38] Cortaredona S, Ventelou B. The extra cost of comorbidity: multiple illnesses and the economic burden of non-communicable diseases. BMC Med. 2017; 5 (1): 216. doi: 10.1186/s12916-017-0978-2.
[39] Hong J, Lee W. K., Kim, M. K., Lee, B. E., Shin, S. D, Park, H. Effect of comorbidity on length of hospital stay and in-hospital mortality among unintentionally injured patients. Accid Anal Prev. 2013; 52: 44-50.
[40] Parappil A, Depczynski B, Collett P, Marks GB. Effect of comorbid diabetes on length of stay and risk of death in patients admitted with acute exacerbations of COPD. Respirology. 2010; 15 (6): 918-22.
Cite This Article
  • APA Style

    Mohammed Takroni, Collins Ogbeivor, Nargis Mirza, Mohammed Al-Subaie, Mohammed Al-Zahrani. (2023). The Impact of Common Comorbidities on the Cardiopulmonary Rehabilitation Outcomes and Cost of Care for Post-CABG Surgery Patients . Cardiology and Cardiovascular Research, 7(4), 75-81. https://doi.org/10.11648/j.ccr.20230704.12

    Copy | Download

    ACS Style

    Mohammed Takroni; Collins Ogbeivor; Nargis Mirza; Mohammed Al-Subaie; Mohammed Al-Zahrani. The Impact of Common Comorbidities on the Cardiopulmonary Rehabilitation Outcomes and Cost of Care for Post-CABG Surgery Patients . Cardiol. Cardiovasc. Res. 2023, 7(4), 75-81. doi: 10.11648/j.ccr.20230704.12

    Copy | Download

    AMA Style

    Mohammed Takroni, Collins Ogbeivor, Nargis Mirza, Mohammed Al-Subaie, Mohammed Al-Zahrani. The Impact of Common Comorbidities on the Cardiopulmonary Rehabilitation Outcomes and Cost of Care for Post-CABG Surgery Patients . Cardiol Cardiovasc Res. 2023;7(4):75-81. doi: 10.11648/j.ccr.20230704.12

    Copy | Download

  • @article{10.11648/j.ccr.20230704.12,
      author = {Mohammed Takroni and Collins Ogbeivor and Nargis Mirza and Mohammed Al-Subaie and Mohammed Al-Zahrani},
      title = {The Impact of Common Comorbidities on the Cardiopulmonary Rehabilitation Outcomes and Cost of Care for Post-CABG Surgery Patients
    
    	
    },
      journal = {Cardiology and Cardiovascular Research},
      volume = {7},
      number = {4},
      pages = {75-81},
      doi = {10.11648/j.ccr.20230704.12},
      url = {https://doi.org/10.11648/j.ccr.20230704.12},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ccr.20230704.12},
      abstract = {Background: The incidence of coronary Heart Disease (CHD) has increased globally, including in Saudi Arabia. Consequently, the use of coronary artery bypass graft (CABG) surgery, one of the most valuable solutions, has also increased. Common comorbidities (CMs) such as diabetes mellitus (DM), hypertension (HTN), peripheral vascular disease (PVD), chronic obstructive pulmonary disease (COPD), peptic ulcer disease, dialysis-dependent renal failure, and obesity have been reported to adversely affect rehabilitation outcomes, increase hospital length of stay (LOS), and increase the cost of care for post-CABG surgery patients. Despite these facts, no previous studies have assessed the effect of comorbidities on Cardiac Rehabilitation outcomes, cost of care, and length of hospital stay in post-CABG surgery patients in the Saudi Population. Objective: To assess the effect of cardiac comorbidities on the outcomes of CR intervention in CABG patients and examine how these comorbidities affect the length of stay in the intensive care unit (ICU) and hospital, as well as the cost of care. Methods: A retrospective cohort study was conducted to follow-up post-CABG patients over two years, from 2020 to 2022. A total of 62 male and female patients who met the inclusion criteria were included in this study. The subjects were divided into two groups based on the CM size. Group I consisted of patients with (> 4 CMs), whereas Group II consisted of patients with (<3 CMs). Results: Group I had a higher mean score of comorbidities (CMs) at 5.09 ± 2.43, which resulted in longer stays in the ICU at 4.34 + 2.24 and in the hospital at 9.16 + 4.63 compared to Group II at 3.43 ± 1.48 and 7.2 ± 1.47, respectively. Group II had higher total cost of care. Conclusions: This study found that patients with multiple comorbidities such as DM, HTN, and dyslipidemia had longer hospital and ICU stays and higher care costs.
    },
     year = {2023}
    }
    

    Copy | Download

  • TY  - JOUR
    T1  - The Impact of Common Comorbidities on the Cardiopulmonary Rehabilitation Outcomes and Cost of Care for Post-CABG Surgery Patients
    
    	
    
    AU  - Mohammed Takroni
    AU  - Collins Ogbeivor
    AU  - Nargis Mirza
    AU  - Mohammed Al-Subaie
    AU  - Mohammed Al-Zahrani
    Y1  - 2023/10/28
    PY  - 2023
    N1  - https://doi.org/10.11648/j.ccr.20230704.12
    DO  - 10.11648/j.ccr.20230704.12
    T2  - Cardiology and Cardiovascular Research
    JF  - Cardiology and Cardiovascular Research
    JO  - Cardiology and Cardiovascular Research
    SP  - 75
    EP  - 81
    PB  - Science Publishing Group
    SN  - 2578-8914
    UR  - https://doi.org/10.11648/j.ccr.20230704.12
    AB  - Background: The incidence of coronary Heart Disease (CHD) has increased globally, including in Saudi Arabia. Consequently, the use of coronary artery bypass graft (CABG) surgery, one of the most valuable solutions, has also increased. Common comorbidities (CMs) such as diabetes mellitus (DM), hypertension (HTN), peripheral vascular disease (PVD), chronic obstructive pulmonary disease (COPD), peptic ulcer disease, dialysis-dependent renal failure, and obesity have been reported to adversely affect rehabilitation outcomes, increase hospital length of stay (LOS), and increase the cost of care for post-CABG surgery patients. Despite these facts, no previous studies have assessed the effect of comorbidities on Cardiac Rehabilitation outcomes, cost of care, and length of hospital stay in post-CABG surgery patients in the Saudi Population. Objective: To assess the effect of cardiac comorbidities on the outcomes of CR intervention in CABG patients and examine how these comorbidities affect the length of stay in the intensive care unit (ICU) and hospital, as well as the cost of care. Methods: A retrospective cohort study was conducted to follow-up post-CABG patients over two years, from 2020 to 2022. A total of 62 male and female patients who met the inclusion criteria were included in this study. The subjects were divided into two groups based on the CM size. Group I consisted of patients with (> 4 CMs), whereas Group II consisted of patients with (<3 CMs). Results: Group I had a higher mean score of comorbidities (CMs) at 5.09 ± 2.43, which resulted in longer stays in the ICU at 4.34 + 2.24 and in the hospital at 9.16 + 4.63 compared to Group II at 3.43 ± 1.48 and 7.2 ± 1.47, respectively. Group II had higher total cost of care. Conclusions: This study found that patients with multiple comorbidities such as DM, HTN, and dyslipidemia had longer hospital and ICU stays and higher care costs.
    
    VL  - 7
    IS  - 4
    ER  - 

    Copy | Download

Author Information
  • Physical Rehabilitation Department, King Faisal Specialist Hospital &Research Center, Riyadh, Saudi Arabia

  • Physical Rehabilitation Department, King Faisal Specialist Hospital &Research Center, Riyadh, Saudi Arabia

  • Physical Rehabilitation Department, King Faisal Specialist Hospital &Research Center, Riyadh, Saudi Arabia

  • Physical Rehabilitation Department, King Faisal Specialist Hospital &Research Center, Riyadh, Saudi Arabia

  • Physical Rehabilitation Department, King Faisal Specialist Hospital &Research Center, Riyadh, Saudi Arabia

  • Sections