Introduction: Invasive brainstem glioma (IBG) is a rare, very aggressive pontine glial tumour. It remains one of the most devastating diagnoses among childhood cancers. We report the observation of an infiltrating brainstem glioma. Observation: This is a 7-year-old girl, with no notable medical and surgical history, who presented in a rapidly progressive context, headaches, vomiting, weakness of the left hemibody, aphasia, tonic-clonic seizures, neurological examination had as particularity, a pyramidal syndrome, a syndrome of intracranial hypertension, and a syndrome of cortical irritation, on the biology one noted a hypercalcemia, encephalic MRI revealed a hyper signal in T2 at the expense of the brainstem, she received corticosteroid therapy, followed by antiepileptic treatment. Evolution resulted in the death of the patient 3 months after the diagnosis. Discussion: Invasive brainstem glioma accounts for about 15% of pediatric brain tumors, presumed diagnosis of invasive brainstem glioma has been progressively made based on clinical and radiological aspects only. For lesions with typical clinical presentation and imaging. Surgery and radiotherapy currently remains the standard treatment, Conclusion: The management of infiltrating gliomas of the brainstem remains delicate, and the prognosis always remains gloomy, our study is an illustrative case, it is one of the very first case of brainstem gliomas described in children in the republic of guinea. Large-scale studies would be necessary to determine the prevalence of the pathology on a national level.
| Published in | Clinical Neurology and Neuroscience (Volume 6, Issue 3) |
| DOI | 10.11648/j.cnn.20220603.12 |
| Page(s) | 41-44 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2024. Published by Science Publishing Group |
Infiltrating Glioma, Brainstem, Chemotherapy
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APA Style
Dore Male, Barry Souleymane Djigue, Conde Kaba, Toure Mohamed Lamine, Conde Mohamed Lamine, et al. (2022). Epilepsy Revealing a Infiltrating Glioma of the Brainstem: A Case Report and Review of the Literature. Clinical Neurology and Neuroscience, 6(3), 41-44. https://doi.org/10.11648/j.cnn.20220603.12
ACS Style
Dore Male; Barry Souleymane Djigue; Conde Kaba; Toure Mohamed Lamine; Conde Mohamed Lamine, et al. Epilepsy Revealing a Infiltrating Glioma of the Brainstem: A Case Report and Review of the Literature. Clin. Neurol. Neurosci. 2022, 6(3), 41-44. doi: 10.11648/j.cnn.20220603.12
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Download@article{10.11648/j.cnn.20220603.12,
author = {Dore Male and Barry Souleymane Djigue and Conde Kaba and Toure Mohamed Lamine and Conde Mohamed Lamine and Igue Kadija and Bogon Victor and Diawara Karinka and Doumbouya Idrissa and Camara Idrissa and Camara Mohamed Salif and Camara Mamady and Bangoura Asmaou and Sidibe Gnouma and Gouled Houssein and Cisse Fode Abass},
title = {Epilepsy Revealing a Infiltrating Glioma of the Brainstem: A Case Report and Review of the Literature},
journal = {Clinical Neurology and Neuroscience},
volume = {6},
number = {3},
pages = {41-44},
doi = {10.11648/j.cnn.20220603.12},
url = {https://doi.org/10.11648/j.cnn.20220603.12},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cnn.20220603.12},
abstract = {Introduction: Invasive brainstem glioma (IBG) is a rare, very aggressive pontine glial tumour. It remains one of the most devastating diagnoses among childhood cancers. We report the observation of an infiltrating brainstem glioma. Observation: This is a 7-year-old girl, with no notable medical and surgical history, who presented in a rapidly progressive context, headaches, vomiting, weakness of the left hemibody, aphasia, tonic-clonic seizures, neurological examination had as particularity, a pyramidal syndrome, a syndrome of intracranial hypertension, and a syndrome of cortical irritation, on the biology one noted a hypercalcemia, encephalic MRI revealed a hyper signal in T2 at the expense of the brainstem, she received corticosteroid therapy, followed by antiepileptic treatment. Evolution resulted in the death of the patient 3 months after the diagnosis. Discussion: Invasive brainstem glioma accounts for about 15% of pediatric brain tumors, presumed diagnosis of invasive brainstem glioma has been progressively made based on clinical and radiological aspects only. For lesions with typical clinical presentation and imaging. Surgery and radiotherapy currently remains the standard treatment, Conclusion: The management of infiltrating gliomas of the brainstem remains delicate, and the prognosis always remains gloomy, our study is an illustrative case, it is one of the very first case of brainstem gliomas described in children in the republic of guinea. Large-scale studies would be necessary to determine the prevalence of the pathology on a national level.},
year = {2022}
}
TY - JOUR T1 - Epilepsy Revealing a Infiltrating Glioma of the Brainstem: A Case Report and Review of the Literature AU - Dore Male AU - Barry Souleymane Djigue AU - Conde Kaba AU - Toure Mohamed Lamine AU - Conde Mohamed Lamine AU - Igue Kadija AU - Bogon Victor AU - Diawara Karinka AU - Doumbouya Idrissa AU - Camara Idrissa AU - Camara Mohamed Salif AU - Camara Mamady AU - Bangoura Asmaou AU - Sidibe Gnouma AU - Gouled Houssein AU - Cisse Fode Abass Y1 - 2022/07/28 PY - 2022 N1 - https://doi.org/10.11648/j.cnn.20220603.12 DO - 10.11648/j.cnn.20220603.12 T2 - Clinical Neurology and Neuroscience JF - Clinical Neurology and Neuroscience JO - Clinical Neurology and Neuroscience SP - 41 EP - 44 PB - Science Publishing Group SN - 2578-8930 UR - https://doi.org/10.11648/j.cnn.20220603.12 AB - Introduction: Invasive brainstem glioma (IBG) is a rare, very aggressive pontine glial tumour. It remains one of the most devastating diagnoses among childhood cancers. We report the observation of an infiltrating brainstem glioma. Observation: This is a 7-year-old girl, with no notable medical and surgical history, who presented in a rapidly progressive context, headaches, vomiting, weakness of the left hemibody, aphasia, tonic-clonic seizures, neurological examination had as particularity, a pyramidal syndrome, a syndrome of intracranial hypertension, and a syndrome of cortical irritation, on the biology one noted a hypercalcemia, encephalic MRI revealed a hyper signal in T2 at the expense of the brainstem, she received corticosteroid therapy, followed by antiepileptic treatment. Evolution resulted in the death of the patient 3 months after the diagnosis. Discussion: Invasive brainstem glioma accounts for about 15% of pediatric brain tumors, presumed diagnosis of invasive brainstem glioma has been progressively made based on clinical and radiological aspects only. For lesions with typical clinical presentation and imaging. Surgery and radiotherapy currently remains the standard treatment, Conclusion: The management of infiltrating gliomas of the brainstem remains delicate, and the prognosis always remains gloomy, our study is an illustrative case, it is one of the very first case of brainstem gliomas described in children in the republic of guinea. Large-scale studies would be necessary to determine the prevalence of the pathology on a national level. VL - 6 IS - 3 ER -
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