Current Status and Underlying Problems of Eradication of Poliomyelitis in the Remaining Endemic Countries

Anthony Chibuogwu Ike; Eleazar Emmanuel Reward; Emmanuel Msugh Mbaawuaga; Obianuju Obiajulu Nnabuife; Ibuchukwu Nkeonyenasoya Alexandra Orabueze

doi:doi:10.11648/j.ejpm.20180601.15

Current Status and Underlying Problems of Eradication of Poliomyelitis in the Remaining Endemic Countries

Anthony Chibuogwu Ike, Eleazar Emmanuel Reward, Emmanuel Msugh Mbaawuaga, Obianuju Obiajulu Nnabuife, Ibuchukwu Nkeonyenasoya Alexandra Orabueze

Published in European Journal of Preventive Medicine (Volume 6, Issue 1)

Received: 6 February 2018 Accepted: 28 February 2018 Published: 15 March 2018

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Abstract

In 1988, the World Health Assembly of the World Health Organization (WHO) launched the Global Polio Eradication Initiative (GPEI), with the resolve to interrupt transmission of wild poliovirus (WPV) worldwide by the year 2000. Eighteen years after the intended year of eradication, that target is yet to be achieved. To investigate the reasons behind this, a check of recent publications on poliomyelitis and polio virus was carried out. The databases and websites of institutions and organizations involved in the polio eradication programme were also checked. The findings showed that although the goal of interrupting polio transmission has not been meet, a lot of progress has been made. By 2006, transmission of WPV had been interrupted in all but four countries: Afghanistan, India, Nigeria and Pakistan. In February 2012, India was delisted from the list of polio-endemic countries leaving the remaining 3 countries as the only endemic countries in the world. Wild type 2 and 3 viruses have both been eliminated from circulations. The number of polio cases in the remaining endemic countries has reduced drastically. Nigeria is close to the target, but is yet to be certified polio-free, having experienced a setback in 2016. However, as long as transmission of WPV continues in these countries, the world cannot be free from the disease, as these countries serve as reservoirs of infection and sources of export of the virus to other countries. To be able to achieve the target of interrupting the transmission of WPV in the remaining endemic countries, the identified problems, particularly conflict in the countries concerned, will have to be factored into the programmes geared toward eradication of the disease.

Published in	European Journal of Preventive Medicine (Volume 6, Issue 1)
DOI	10.11648/j.ejpm.20180601.15
Page(s)	23-28
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Poliomyelitis, Poliovirus, Eradication, Wild Type, Endemic, Afghanistan, Pakistan, Nigeria

References

[1]	H. Yasin, “Polio: the fight of the public against a disease it does not understand with a vaccine it does not trust,” J Pak Med Assoc, vol. 66, no. 5, 2016, pp. 496-497.
[2]	L. Roberts, “New polio cases in Nigeria spur massive response,” Science, vol. 353, no. 6301, 2016, p. 738. doi: 10.1126/science.353.6301.738
[3]	World Health Organization, “Government of Nigeria reports 2 wild polio cases, first since July 2014,” Media Centre Geneva, Switzerland, 2016.
[4]	E. K. Moturi, K. A. Porter, S. G. F. Wassilak, R. H. Tangermann, O. M. Diop, C. C. Burns, and H. Jafari, “Progress towards polio eradication – worldwide, 2013 – 2014,” Morb Mort Wkly Rep Wkly, vol. 63, no. 21, 2014, pp. 468-472.
[5]	I. M. Blake, P. Chenoweth, H. Okayasu, C. A. Donnelly, R. B. Alyward, and N. C. Grassly, “Faster Detection of Poliomyelitis Outbreaks to Support Polio Eradication,” Emerg Infect Dis, vol. 22, no. 3, 2016, pp. 449-456.
[6]	F. S. Hussain, P. Boyle, P. Patel, and R. Sullivan, “Eradicating polio in Pakistan: an analysis of the challenges and solutions to this security and health issue,” Glob Health, vol. 12, 2016, pp. 63-71. doi: 10.1186/s12992-016-0195-3.
[7]	B. Aylward, and T. Yamada, “The polio endgame,” New Engl J Med, vol. 364, no. 24, 2011, pp. 2273-2275.
[8]	N. C. Grassly, “The final stages of the global eradication of poliomyelitis. Phil Trans R Soc B, vol. 368, 2013, pp. 1-14. doi: 10.1098/rstb.2012.0140.
[9]	B. E. Bassey, R. G. Vaz, F. Braka, S. T. Komakech, S. T. Maleghemi, G. U. Akpan, and A. Ejeka-Okocha, “Profiling the immunity status of children with non-polio acute flaccid paralysis who had not received any doses of oral polio vaccine in the South-South region, Nigeria 2011-2014,” Pub Health, vol. 139, 2016, pp. 148-153. doi: 10.1016/j.puhe.2016.05.009.
[10]	V. R. Racaniello, “Picornaviridae: the viruses and their replication”, In: D. M. Knipe, P. M. Howley, D. E. Griffin, R. A. Lamb, M. A. Martin, B. Roizman, and S. E. Straus, (ed). Fields Virology, 4th ed, vol. 1, Lippincott/the Williams & Wilkins Co, New York, 2001, pp. 685-722.
[11]	M. Strauss, D. J. Filman, D. M. Belnap, N. Cheng, R. T. Noel, and J. M. Hogle, “Nectin- like interactions between poliovirus and its receptor trigger conformational changes associated with cell entry,” J Virol, vol. 89, no. 8, 2015, pp. 4143-4157.
[12]	L. Romero-Brey, and R. Bartenschlager, “Membranous replication factories induced by plus-strand RNA viruses,” Viruses, vol. 6, 2014, pp. 2826-2857.
[13]	E. D. Rossignol, J. E. Yang, and E. Bullitt, “The role of electron microscopy in studying the continuum of changes in membranous structures during poliovirus infection,” Viruses, vol. 7, 2015, pp. 5305-5318.
[14]	M. Kabir, and M. S. Afzal, “Epidemiology of polio virus infection in Pakistan and possible risk factors for its transmission,” Asian Pac J Trop Med, vol. 352, 2016, pp. 1-4. doi: 10.1016/j.apjtm.2016.09.006.
[15]	National Primary Health Care Development Agency, “Nigeria Polio Eradication Emergency Plan,” 2017.
[16]	UNICEF, “Afghanistan Polio Update July – September 2016”, 2016.
[17]	WHO, “WHO-recommended standards for surveillance of selected vaccine preventable diseases,” Department of Vaccines and Biologicals Geneva, Switzerland, 2003.
[18]	E. A. Coates, S. Waisbord, J. Awake, R. Solomon, and R. Dey, “Successful polio eradication in Uttar Pradesh, India: the pivotal contribution of the Social Mobilization Network, an NGO/UNICEF collaboration,” Glob Health: Sc and Pract vol. 1, no. 1, 2013, pp. 63-68.
[19]	S. G. F. Wassilak, C. L. Williams, S. C. Mursill, A. B. Dahl, C. Ohuabunwo, and R. H. Tangermann, “Using Acute Flaccid Paralysis Surveillance as a Platform for Vaccine- Preventable Disease Surveillance,” The J Infect Dis, vol. 216, 2017, pp. 293-298.
[20]	WHO, “Polio eradication: experts say Nigeria not ‘out of the woods yet’,” Geneva, Switzerland, 2017. http://www.afro.who.int/news/
[21]	Polio eradication.org, “External Review of Acute Flaccid Paralysis Surveillance for Polio Eradication in Four Regions of Afghanistan,” 2017. Retrieved from http://polioeradication.org/uploads/2017/04
[22]	End Polio Pakistan, “Surveillance,” 2017. Retrieved from http://www.endpolio.com.pk/polioin-pakistan/surveillance
[23]	National Population Commission, “Nigeria population now 182 million-NPC,” Nigeria Population Commission (NPopC), 2017.
[24]	UNESCO, “Literacy statistics metadata information table,” UNESCO Institute for Statistics, September 2015. Retrieved December 2017.
[25]	J. J. R. Bigna, “Polio eradication efforts in regions of geopolitical strife: the Boko Haram threat to efforts in sub-Saharan Africa,” Afr Health Sc, vol. 16, no. 2, 2016, pp. 584-587. doi:10.4314/abs.v16i2.28.
[26]	D. Ali, R. Banda, A. Mohammed, J. Adagadzu, B. Murele, R. Seruyane, J. Makam, P. Mkanda, B. Okpessen, S. G. Tegegne, A. S. Folorunsho, T. B. Erbeto, Y. G. Yehualashet, and R. G. Vaz, “Strengthening routine immunization in areas of northern Nigeria at high risk of polio transmission during 2012-2014,” J Infect Dis, vol. 213, 2016, pp. 147-150.
[27]	N. U. Nasir, S. A. Bandyopadhyay, F. Mntagnani, E. J. Akite, B. E. Mungu, V. I. Uche, and M. A. Ismaila, “Polio elimination in Nigeria: A review,” Human Vac Immunotherap, vol. 12, no. 3, 2016, pp. 658-663.
[28]	W. U. Z. Tariq, “Poliomyelitis, security issues and Pakistan,” J Human Virol Retrovirol, vol. 5, no. 4, 2017, pp. 1-2.
[29]	S. Ghafoor, and N. Sheikh, “Eradication and current status of poliomyelitis in Pakistan: Ground realities,” J Immunol Res, 2016, doi: 10.1155/2016/6837824.
[30]	H. J. Larson, W. S. Schulz, J. D. Tucker, and D. M. D. Smith, “Measuring vaccine confidence: introducing a global vaccine confidence index,” PLoS Curr Outbreaks, 2015, doi: 10.1371/currents.outbreaks.ce0f6177.4.
[31]	H. J. Larson, A. Figueredo, and S. N. Jones, “The state of vaccine confidence 2016: Global insights through a 67-country survey,” EBioMed, vol. 12, 2016, pp. 295-301.
[32]	WHO, “Report of the SAGE working group on vaccine hesitancy,” 2014. Retrieved from http://www.who.int/immunization/sage/meetings/2014/october/1_Report_WORKING_ GROUP vaccine_hesitancy_final.pdf
[33]	EU, “Measles deaths in EU on course to treble,” 2017, Retrieved from http://www.euronews.com/2017/12/06/measles-deaths-in-eu-on-course-to-treble
[34]	O. Yaqub, S. Castle-Clarke, N. Sevdalis, and J. Chataway, “Attitudes to vaccination: a critical review,” Soc Sc Medline, vol. 112, 2014, pp. 1-11.
[35]	M. Pons-Salort, C. C. Burns, H. Lyons, I. M. Blake, H. Jafari, M. S. Oberste, O. M. Kew, and N. C. Grassly, “Preventing vaccine-derived poliovirus emergence during the polio endgame,” PLoS Pathogens vol. 12, no. 7, 2016, e1005728. doi: 10.1371/journal.ppat.1005728.
[36]	G. Sherriff, Z. W. Mufti, G. R. Vaz, W. R. Sutter, and N. C. Grassly, “Estimated effect of inactivated poliovirus vaccine campaigns, Nigeria and Pakistan, January 2014- April 2016,” Emerg Infect Dis vol. 23, no. 2, 2017, pp. 258-263. doi: org/10.3201/eid2302.161210.
[37]	R. J. D. Tebbens, L. M. Hampton, and K. M. Thompson, “Implementation of coordinated global serotype 2 oral poliovirus vaccine cessation: risks of inadvertent trivalent oral poliovirus vaccine use,” BMC Infect Dis vol. 16: 2016, pp. 237-247. doi: 10.1186/s12879-016-1537-8.

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APA Style

Anthony Chibuogwu Ike, Eleazar Emmanuel Reward, Emmanuel Msugh Mbaawuaga, Obianuju Obiajulu Nnabuife, Ibuchukwu Nkeonyenasoya Alexandra Orabueze. (2018). Current Status and Underlying Problems of Eradication of Poliomyelitis in the Remaining Endemic Countries. European Journal of Preventive Medicine, 6(1), 23-28. https://doi.org/10.11648/j.ejpm.20180601.15

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ACS Style

Anthony Chibuogwu Ike; Eleazar Emmanuel Reward; Emmanuel Msugh Mbaawuaga; Obianuju Obiajulu Nnabuife; Ibuchukwu Nkeonyenasoya Alexandra Orabueze. Current Status and Underlying Problems of Eradication of Poliomyelitis in the Remaining Endemic Countries. Eur. J. Prev. Med. 2018, 6(1), 23-28. doi: 10.11648/j.ejpm.20180601.15

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AMA Style

Anthony Chibuogwu Ike, Eleazar Emmanuel Reward, Emmanuel Msugh Mbaawuaga, Obianuju Obiajulu Nnabuife, Ibuchukwu Nkeonyenasoya Alexandra Orabueze. Current Status and Underlying Problems of Eradication of Poliomyelitis in the Remaining Endemic Countries. Eur J Prev Med. 2018;6(1):23-28. doi: 10.11648/j.ejpm.20180601.15

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@article{10.11648/j.ejpm.20180601.15,
  author = {Anthony Chibuogwu Ike and Eleazar Emmanuel Reward and Emmanuel Msugh Mbaawuaga and Obianuju Obiajulu Nnabuife and Ibuchukwu Nkeonyenasoya Alexandra Orabueze},
  title = {Current Status and Underlying Problems of Eradication of Poliomyelitis in the Remaining Endemic Countries},
  journal = {European Journal of Preventive Medicine},
  volume = {6},
  number = {1},
  pages = {23-28},
  doi = {10.11648/j.ejpm.20180601.15},
  url = {https://doi.org/10.11648/j.ejpm.20180601.15},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ejpm.20180601.15},
  abstract = {In 1988, the World Health Assembly of the World Health Organization (WHO) launched the Global Polio Eradication Initiative (GPEI), with the resolve to interrupt transmission of wild poliovirus (WPV) worldwide by the year 2000. Eighteen years after the intended year of eradication, that target is yet to be achieved. To investigate the reasons behind this, a check of recent publications on poliomyelitis and polio virus was carried out. The databases and websites of institutions and organizations involved in the polio eradication programme were also checked. The findings showed that although the goal of interrupting polio transmission has not been meet, a lot of progress has been made. By 2006, transmission of WPV had been interrupted in all but four countries: Afghanistan, India, Nigeria and Pakistan. In February 2012, India was delisted from the list of polio-endemic countries leaving the remaining 3 countries as the only endemic countries in the world. Wild type 2 and 3 viruses have both been eliminated from circulations. The number of polio cases in the remaining endemic countries has reduced drastically. Nigeria is close to the target, but is yet to be certified polio-free, having experienced a setback in 2016. However, as long as transmission of WPV continues in these countries, the world cannot be free from the disease, as these countries serve as reservoirs of infection and sources of export of the virus to other countries. To be able to achieve the target of interrupting the transmission of WPV in the remaining endemic countries, the identified problems, particularly conflict in the countries concerned, will have to be factored into the programmes geared toward eradication of the disease.},
 year = {2018}
}

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TY  - JOUR
T1  - Current Status and Underlying Problems of Eradication of Poliomyelitis in the Remaining Endemic Countries
AU  - Anthony Chibuogwu Ike
AU  - Eleazar Emmanuel Reward
AU  - Emmanuel Msugh Mbaawuaga
AU  - Obianuju Obiajulu Nnabuife
AU  - Ibuchukwu Nkeonyenasoya Alexandra Orabueze
Y1  - 2018/03/15
PY  - 2018
N1  - https://doi.org/10.11648/j.ejpm.20180601.15
DO  - 10.11648/j.ejpm.20180601.15
T2  - European Journal of Preventive Medicine
JF  - European Journal of Preventive Medicine
JO  - European Journal of Preventive Medicine
SP  - 23
EP  - 28
PB  - Science Publishing Group
SN  - 2330-8230
UR  - https://doi.org/10.11648/j.ejpm.20180601.15
AB  - In 1988, the World Health Assembly of the World Health Organization (WHO) launched the Global Polio Eradication Initiative (GPEI), with the resolve to interrupt transmission of wild poliovirus (WPV) worldwide by the year 2000. Eighteen years after the intended year of eradication, that target is yet to be achieved. To investigate the reasons behind this, a check of recent publications on poliomyelitis and polio virus was carried out. The databases and websites of institutions and organizations involved in the polio eradication programme were also checked. The findings showed that although the goal of interrupting polio transmission has not been meet, a lot of progress has been made. By 2006, transmission of WPV had been interrupted in all but four countries: Afghanistan, India, Nigeria and Pakistan. In February 2012, India was delisted from the list of polio-endemic countries leaving the remaining 3 countries as the only endemic countries in the world. Wild type 2 and 3 viruses have both been eliminated from circulations. The number of polio cases in the remaining endemic countries has reduced drastically. Nigeria is close to the target, but is yet to be certified polio-free, having experienced a setback in 2016. However, as long as transmission of WPV continues in these countries, the world cannot be free from the disease, as these countries serve as reservoirs of infection and sources of export of the virus to other countries. To be able to achieve the target of interrupting the transmission of WPV in the remaining endemic countries, the identified problems, particularly conflict in the countries concerned, will have to be factored into the programmes geared toward eradication of the disease.
VL  - 6
IS  - 1
ER  -

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Author Information

Anthony Chibuogwu Ike

Department of Microbiology, University of Nigeria, Nsukka, Nigeria
Eleazar Emmanuel Reward

Department of Microbiology, University of Nigeria, Nsukka, Nigeria
Emmanuel Msugh Mbaawuaga

Department of Biological Sciences, Benue State University, Makurdi, Nigeria
Obianuju Obiajulu Nnabuife

Department of Microbiology, University of Nigeria, Nsukka, Nigeria
Ibuchukwu Nkeonyenasoya Alexandra Orabueze

Department of Microbiology, University of Nigeria, Nsukka, Nigeria

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Anthony Chibuogwu Ike, Eleazar Emmanuel Reward, Emmanuel Msugh Mbaawuaga, Obianuju Obiajulu Nnabuife, Ibuchukwu Nkeonyenasoya Alexandra Orabueze. (2018). Current Status and Underlying Problems of Eradication of Poliomyelitis in the Remaining Endemic Countries. European Journal of Preventive Medicine, 6(1), 23-28. https://doi.org/10.11648/j.ejpm.20180601.15

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ACS Style

Anthony Chibuogwu Ike; Eleazar Emmanuel Reward; Emmanuel Msugh Mbaawuaga; Obianuju Obiajulu Nnabuife; Ibuchukwu Nkeonyenasoya Alexandra Orabueze. Current Status and Underlying Problems of Eradication of Poliomyelitis in the Remaining Endemic Countries. Eur. J. Prev. Med. 2018, 6(1), 23-28. doi: 10.11648/j.ejpm.20180601.15

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AMA Style

Anthony Chibuogwu Ike, Eleazar Emmanuel Reward, Emmanuel Msugh Mbaawuaga, Obianuju Obiajulu Nnabuife, Ibuchukwu Nkeonyenasoya Alexandra Orabueze. Current Status and Underlying Problems of Eradication of Poliomyelitis in the Remaining Endemic Countries. Eur J Prev Med. 2018;6(1):23-28. doi: 10.11648/j.ejpm.20180601.15

Copy | Download

@article{10.11648/j.ejpm.20180601.15,
  author = {Anthony Chibuogwu Ike and Eleazar Emmanuel Reward and Emmanuel Msugh Mbaawuaga and Obianuju Obiajulu Nnabuife and Ibuchukwu Nkeonyenasoya Alexandra Orabueze},
  title = {Current Status and Underlying Problems of Eradication of Poliomyelitis in the Remaining Endemic Countries},
  journal = {European Journal of Preventive Medicine},
  volume = {6},
  number = {1},
  pages = {23-28},
  doi = {10.11648/j.ejpm.20180601.15},
  url = {https://doi.org/10.11648/j.ejpm.20180601.15},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ejpm.20180601.15},
  abstract = {In 1988, the World Health Assembly of the World Health Organization (WHO) launched the Global Polio Eradication Initiative (GPEI), with the resolve to interrupt transmission of wild poliovirus (WPV) worldwide by the year 2000. Eighteen years after the intended year of eradication, that target is yet to be achieved. To investigate the reasons behind this, a check of recent publications on poliomyelitis and polio virus was carried out. The databases and websites of institutions and organizations involved in the polio eradication programme were also checked. The findings showed that although the goal of interrupting polio transmission has not been meet, a lot of progress has been made. By 2006, transmission of WPV had been interrupted in all but four countries: Afghanistan, India, Nigeria and Pakistan. In February 2012, India was delisted from the list of polio-endemic countries leaving the remaining 3 countries as the only endemic countries in the world. Wild type 2 and 3 viruses have both been eliminated from circulations. The number of polio cases in the remaining endemic countries has reduced drastically. Nigeria is close to the target, but is yet to be certified polio-free, having experienced a setback in 2016. However, as long as transmission of WPV continues in these countries, the world cannot be free from the disease, as these countries serve as reservoirs of infection and sources of export of the virus to other countries. To be able to achieve the target of interrupting the transmission of WPV in the remaining endemic countries, the identified problems, particularly conflict in the countries concerned, will have to be factored into the programmes geared toward eradication of the disease.},
 year = {2018}
}

Copy | Download

TY  - JOUR
T1  - Current Status and Underlying Problems of Eradication of Poliomyelitis in the Remaining Endemic Countries
AU  - Anthony Chibuogwu Ike
AU  - Eleazar Emmanuel Reward
AU  - Emmanuel Msugh Mbaawuaga
AU  - Obianuju Obiajulu Nnabuife
AU  - Ibuchukwu Nkeonyenasoya Alexandra Orabueze
Y1  - 2018/03/15
PY  - 2018
N1  - https://doi.org/10.11648/j.ejpm.20180601.15
DO  - 10.11648/j.ejpm.20180601.15
T2  - European Journal of Preventive Medicine
JF  - European Journal of Preventive Medicine
JO  - European Journal of Preventive Medicine
SP  - 23
EP  - 28
PB  - Science Publishing Group
SN  - 2330-8230
UR  - https://doi.org/10.11648/j.ejpm.20180601.15
AB  - In 1988, the World Health Assembly of the World Health Organization (WHO) launched the Global Polio Eradication Initiative (GPEI), with the resolve to interrupt transmission of wild poliovirus (WPV) worldwide by the year 2000. Eighteen years after the intended year of eradication, that target is yet to be achieved. To investigate the reasons behind this, a check of recent publications on poliomyelitis and polio virus was carried out. The databases and websites of institutions and organizations involved in the polio eradication programme were also checked. The findings showed that although the goal of interrupting polio transmission has not been meet, a lot of progress has been made. By 2006, transmission of WPV had been interrupted in all but four countries: Afghanistan, India, Nigeria and Pakistan. In February 2012, India was delisted from the list of polio-endemic countries leaving the remaining 3 countries as the only endemic countries in the world. Wild type 2 and 3 viruses have both been eliminated from circulations. The number of polio cases in the remaining endemic countries has reduced drastically. Nigeria is close to the target, but is yet to be certified polio-free, having experienced a setback in 2016. However, as long as transmission of WPV continues in these countries, the world cannot be free from the disease, as these countries serve as reservoirs of infection and sources of export of the virus to other countries. To be able to achieve the target of interrupting the transmission of WPV in the remaining endemic countries, the identified problems, particularly conflict in the countries concerned, will have to be factored into the programmes geared toward eradication of the disease.
VL  - 6
IS  - 1
ER  -

Copy | Download