Background: Mastocytosis is a clinical condition occurring from birth to adulthood. It mainly involves the skin solely or in association with other organs such as the liver, bone marrow, spleen and lymph nodes. A bimodal distribution presenting in children from birth to 2 years of age and in patients older than 15 is commonly described. Case Information: An eight-year-old male patient presented with macules and papules on the trunk and limbs for 6 months. The rash worsened after bathing and physical activity. Results: The symptoms were compatible with cutaneous mastocytosis and confirmed histologically. Conclusion: Patients with mastocytosis may be asymptomatic or have symptoms due to mast cells degranulation – itch, flush, headache, syncope, gastrointestinal complaints of abdominal pain and diarrhea. Diagnosis of cutaneous mastocytosis is based on clinical morphology of skin lesions, positive Darier`s sign and histological skin lesions stained for tryptase and/or CD117. Therapeutic management involves avoiding triggers, H1-/H2- receptor blockers and symptomatic medications. All patients with cutaneous mastocytosis require regular follow-up examinations.
| Published in | International Journal of Clinical Dermatology (Volume 5, Issue 1) |
| DOI | 10.11648/j.ijcd.20220501.11 |
| Page(s) | 1-5 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2024. Published by Science Publishing Group |
Mastocytosis, Child, Urticaria Pigmentosa, Cutaneous Mastocytosis
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APA Style
Tsveta Kalinova, Valentina Broshtilova, Yoanna Velevska-Vatova, Sonya Marina. (2022). Cutaneous Mastocytosis in an 8-year-old Child: Case Report and Review of the Literature. International Journal of Clinical Dermatology, 5(1), 1-5. https://doi.org/10.11648/j.ijcd.20220501.11
ACS Style
Tsveta Kalinova; Valentina Broshtilova; Yoanna Velevska-Vatova; Sonya Marina. Cutaneous Mastocytosis in an 8-year-old Child: Case Report and Review of the Literature. Int. J. Clin. Dermatol. 2022, 5(1), 1-5. doi: 10.11648/j.ijcd.20220501.11
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Download@article{10.11648/j.ijcd.20220501.11,
author = {Tsveta Kalinova and Valentina Broshtilova and Yoanna Velevska-Vatova and Sonya Marina},
title = {Cutaneous Mastocytosis in an 8-year-old Child: Case Report and Review of the Literature},
journal = {International Journal of Clinical Dermatology},
volume = {5},
number = {1},
pages = {1-5},
doi = {10.11648/j.ijcd.20220501.11},
url = {https://doi.org/10.11648/j.ijcd.20220501.11},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcd.20220501.11},
abstract = {Background: Mastocytosis is a clinical condition occurring from birth to adulthood. It mainly involves the skin solely or in association with other organs such as the liver, bone marrow, spleen and lymph nodes. A bimodal distribution presenting in children from birth to 2 years of age and in patients older than 15 is commonly described. Case Information: An eight-year-old male patient presented with macules and papules on the trunk and limbs for 6 months. The rash worsened after bathing and physical activity. Results: The symptoms were compatible with cutaneous mastocytosis and confirmed histologically. Conclusion: Patients with mastocytosis may be asymptomatic or have symptoms due to mast cells degranulation – itch, flush, headache, syncope, gastrointestinal complaints of abdominal pain and diarrhea. Diagnosis of cutaneous mastocytosis is based on clinical morphology of skin lesions, positive Darier`s sign and histological skin lesions stained for tryptase and/or CD117. Therapeutic management involves avoiding triggers, H1-/H2- receptor blockers and symptomatic medications. All patients with cutaneous mastocytosis require regular follow-up examinations.},
year = {2022}
}
TY - JOUR T1 - Cutaneous Mastocytosis in an 8-year-old Child: Case Report and Review of the Literature AU - Tsveta Kalinova AU - Valentina Broshtilova AU - Yoanna Velevska-Vatova AU - Sonya Marina Y1 - 2022/09/14 PY - 2022 N1 - https://doi.org/10.11648/j.ijcd.20220501.11 DO - 10.11648/j.ijcd.20220501.11 T2 - International Journal of Clinical Dermatology JF - International Journal of Clinical Dermatology JO - International Journal of Clinical Dermatology SP - 1 EP - 5 PB - Science Publishing Group SN - 2995-1305 UR - https://doi.org/10.11648/j.ijcd.20220501.11 AB - Background: Mastocytosis is a clinical condition occurring from birth to adulthood. It mainly involves the skin solely or in association with other organs such as the liver, bone marrow, spleen and lymph nodes. A bimodal distribution presenting in children from birth to 2 years of age and in patients older than 15 is commonly described. Case Information: An eight-year-old male patient presented with macules and papules on the trunk and limbs for 6 months. The rash worsened after bathing and physical activity. Results: The symptoms were compatible with cutaneous mastocytosis and confirmed histologically. Conclusion: Patients with mastocytosis may be asymptomatic or have symptoms due to mast cells degranulation – itch, flush, headache, syncope, gastrointestinal complaints of abdominal pain and diarrhea. Diagnosis of cutaneous mastocytosis is based on clinical morphology of skin lesions, positive Darier`s sign and histological skin lesions stained for tryptase and/or CD117. Therapeutic management involves avoiding triggers, H1-/H2- receptor blockers and symptomatic medications. All patients with cutaneous mastocytosis require regular follow-up examinations. VL - 5 IS - 1 ER -
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