Discrepancy Between cTNM and pTNM in Patients with Oral Squamous Cell Carcinoma

Ramish Tariq; Sana Mehmood Qureshi; Muhammad Usman Khalid; Omer Sefvan Janjua; Khurram Jah Zafar; Malik Muhammad Usama

doi:doi:10.11648/j.ijcoms.20210701.11

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Discrepancy Between cTNM and pTNM in Patients with Oral Squamous Cell Carcinoma

Ramish Tariq, Sana Mehmood Qureshi, Muhammad Usman Khalid, Omer Sefvan Janjua, Khurram Jah Zafar, Malik Muhammad Usama

Published in International Journal of Clinical Oral and Maxillofacial Surgery (Volume 7, Issue 1)

Received: 13 December 2020 Accepted: 11 January 2021 Published: 22 January 2021

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Abstract

Objective: To analyze discrepancy between cTNM and pTNM in patients with squamous cell carcinoma of oral cavity. Study design: Cross-sectional study. Setting & Duration: Cases of OSCC treated in Oral and Maxillofacial Surgery Department, Allied Hospital Faisalabad from December 2017 to November 2020 were included in the study. Methodology: Total 80 patients with biopsy proven OSCC were enrolled in the study. cTNM staging was based on clinical examination and CT/MRI. Primary tumor excision along with neck dissection was done in all patients. Postoperatively pTNM staging was done and compared to cTNM. The clinical, radiological and histopathological lymph node status of patients were compared. Results: Among 80 patients, male to female ratio was 1.6:1. The mean of age was 50.2±10.2 years. The most common site in our center was the lateral border of the tongue. The total coincidence rate between clinical T-stage and pathological T-stage was 57.5%. On comparison between the clinical and pathological N-stage the total coincidence rate was 40%. The total coincidence rate between cTNM and pTNM was 35% and the p-value was insignificant (p>0.05). The sensitivity of CT/MRI for N-stage was 53.3% and specificity was 60% and positive predictive value (PPV) was 53.3% and negative predictive value (NPV) was 60%. Conclusion: Disparity between cTNM and pTNM of OSCC exits that could affect the treatment planning and prognosis.

Published in	International Journal of Clinical Oral and Maxillofacial Surgery (Volume 7, Issue 1)
DOI	10.11648/j.ijcoms.20210701.11
Page(s)	1-5
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Oral cancer, Squamous Cell Carcinoma, TNM Staging

References

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Ramish Tariq, Sana Mehmood Qureshi, Muhammad Usman Khalid, Omer Sefvan Janjua, Khurram Jah Zafar, et al. (2021). Discrepancy Between cTNM and pTNM in Patients with Oral Squamous Cell Carcinoma. International Journal of Clinical Oral and Maxillofacial Surgery, 7(1), 1-5. https://doi.org/10.11648/j.ijcoms.20210701.11

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ACS Style

Ramish Tariq; Sana Mehmood Qureshi; Muhammad Usman Khalid; Omer Sefvan Janjua; Khurram Jah Zafar, et al. Discrepancy Between cTNM and pTNM in Patients with Oral Squamous Cell Carcinoma. Int. J. Clin. Oral Maxillofac. Surg. 2021, 7(1), 1-5. doi: 10.11648/j.ijcoms.20210701.11

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AMA Style

Ramish Tariq, Sana Mehmood Qureshi, Muhammad Usman Khalid, Omer Sefvan Janjua, Khurram Jah Zafar, et al. Discrepancy Between cTNM and pTNM in Patients with Oral Squamous Cell Carcinoma. Int J Clin Oral Maxillofac Surg. 2021;7(1):1-5. doi: 10.11648/j.ijcoms.20210701.11

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@article{10.11648/j.ijcoms.20210701.11,
  author = {Ramish Tariq and Sana Mehmood Qureshi and Muhammad Usman Khalid and Omer Sefvan Janjua and Khurram Jah Zafar and Malik Muhammad Usama},
  title = {Discrepancy Between cTNM and pTNM in Patients with Oral Squamous Cell Carcinoma},
  journal = {International Journal of Clinical Oral and Maxillofacial Surgery},
  volume = {7},
  number = {1},
  pages = {1-5},
  doi = {10.11648/j.ijcoms.20210701.11},
  url = {https://doi.org/10.11648/j.ijcoms.20210701.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcoms.20210701.11},
  abstract = {Objective: To analyze discrepancy between cTNM and pTNM in patients with squamous cell carcinoma of oral cavity. Study design: Cross-sectional study. Setting & Duration: Cases of OSCC treated in Oral and Maxillofacial Surgery Department, Allied Hospital Faisalabad from December 2017 to November 2020 were included in the study. Methodology: Total 80 patients with biopsy proven OSCC were enrolled in the study. cTNM staging was based on clinical examination and CT/MRI. Primary tumor excision along with neck dissection was done in all patients. Postoperatively pTNM staging was done and compared to cTNM. The clinical, radiological and histopathological lymph node status of patients were compared. Results: Among 80 patients, male to female ratio was 1.6:1. The mean of age was 50.2±10.2 years. The most common site in our center was the lateral border of the tongue. The total coincidence rate between clinical T-stage and pathological T-stage was 57.5%. On comparison between the clinical and pathological N-stage the total coincidence rate was 40%. The total coincidence rate between cTNM and pTNM was 35% and the p-value was insignificant (p>0.05). The sensitivity of CT/MRI for N-stage was 53.3% and specificity was 60% and positive predictive value (PPV) was 53.3% and negative predictive value (NPV) was 60%. Conclusion: Disparity between cTNM and pTNM of OSCC exits that could affect the treatment planning and prognosis.},
 year = {2021}
}

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TY - JOUR
T1 - Discrepancy Between cTNM and pTNM in Patients with Oral Squamous Cell Carcinoma
AU - Ramish Tariq
AU - Sana Mehmood Qureshi
AU - Muhammad Usman Khalid
AU - Omer Sefvan Janjua
AU - Khurram Jah Zafar
AU - Malik Muhammad Usama
Y1 - 2021/01/22
PY - 2021
N1 - https://doi.org/10.11648/j.ijcoms.20210701.11
DO - 10.11648/j.ijcoms.20210701.11
T2 - International Journal of Clinical Oral and Maxillofacial Surgery
JF - International Journal of Clinical Oral and Maxillofacial Surgery
JO - International Journal of Clinical Oral and Maxillofacial Surgery
SP - 1
EP - 5
PB - Science Publishing Group
SN - 2472-1344
UR - https://doi.org/10.11648/j.ijcoms.20210701.11
AB - Objective: To analyze discrepancy between cTNM and pTNM in patients with squamous cell carcinoma of oral cavity. Study design: Cross-sectional study. Setting & Duration: Cases of OSCC treated in Oral and Maxillofacial Surgery Department, Allied Hospital Faisalabad from December 2017 to November 2020 were included in the study. Methodology: Total 80 patients with biopsy proven OSCC were enrolled in the study. cTNM staging was based on clinical examination and CT/MRI. Primary tumor excision along with neck dissection was done in all patients. Postoperatively pTNM staging was done and compared to cTNM. The clinical, radiological and histopathological lymph node status of patients were compared. Results: Among 80 patients, male to female ratio was 1.6:1. The mean of age was 50.2±10.2 years. The most common site in our center was the lateral border of the tongue. The total coincidence rate between clinical T-stage and pathological T-stage was 57.5%. On comparison between the clinical and pathological N-stage the total coincidence rate was 40%. The total coincidence rate between cTNM and pTNM was 35% and the p-value was insignificant (p>0.05). The sensitivity of CT/MRI for N-stage was 53.3% and specificity was 60% and positive predictive value (PPV) was 53.3% and negative predictive value (NPV) was 60%. Conclusion: Disparity between cTNM and pTNM of OSCC exits that could affect the treatment planning and prognosis.
VL - 7
IS - 1
ER -

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Author Information

Ramish Tariq

Oral and Maxillofacial Surgery, Allied Hospital, Faisalabad, Pakistan
Sana Mehmood Qureshi

Department of Oral Pathology, Allied Hospital, Faisalabad, Pakistan
Muhammad Usman Khalid

Oral and Maxillofacial Surgery, Allied Hospital, Faisalabad, Pakistan
Omer Sefvan Janjua

Oral and Maxillofacial Surgery, Allied Hospital, Faisalabad, Pakistan
Khurram Jah Zafar

Oral and Maxillofacial Surgery, Allied Hospital, Faisalabad, Pakistan
Malik Muhammad Usama

Oral and Maxillofacial Surgery, Allied Hospital, Faisalabad, Pakistan

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Ramish Tariq, Sana Mehmood Qureshi, Muhammad Usman Khalid, Omer Sefvan Janjua, Khurram Jah Zafar, et al. (2021). Discrepancy Between cTNM and pTNM in Patients with Oral Squamous Cell Carcinoma. International Journal of Clinical Oral and Maxillofacial Surgery, 7(1), 1-5. https://doi.org/10.11648/j.ijcoms.20210701.11

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ACS Style

Ramish Tariq; Sana Mehmood Qureshi; Muhammad Usman Khalid; Omer Sefvan Janjua; Khurram Jah Zafar, et al. Discrepancy Between cTNM and pTNM in Patients with Oral Squamous Cell Carcinoma. Int. J. Clin. Oral Maxillofac. Surg. 2021, 7(1), 1-5. doi: 10.11648/j.ijcoms.20210701.11

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AMA Style

Ramish Tariq, Sana Mehmood Qureshi, Muhammad Usman Khalid, Omer Sefvan Janjua, Khurram Jah Zafar, et al. Discrepancy Between cTNM and pTNM in Patients with Oral Squamous Cell Carcinoma. Int J Clin Oral Maxillofac Surg. 2021;7(1):1-5. doi: 10.11648/j.ijcoms.20210701.11

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@article{10.11648/j.ijcoms.20210701.11,
  author = {Ramish Tariq and Sana Mehmood Qureshi and Muhammad Usman Khalid and Omer Sefvan Janjua and Khurram Jah Zafar and Malik Muhammad Usama},
  title = {Discrepancy Between cTNM and pTNM in Patients with Oral Squamous Cell Carcinoma},
  journal = {International Journal of Clinical Oral and Maxillofacial Surgery},
  volume = {7},
  number = {1},
  pages = {1-5},
  doi = {10.11648/j.ijcoms.20210701.11},
  url = {https://doi.org/10.11648/j.ijcoms.20210701.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcoms.20210701.11},
  abstract = {Objective: To analyze discrepancy between cTNM and pTNM in patients with squamous cell carcinoma of oral cavity. Study design: Cross-sectional study. Setting & Duration: Cases of OSCC treated in Oral and Maxillofacial Surgery Department, Allied Hospital Faisalabad from December 2017 to November 2020 were included in the study. Methodology: Total 80 patients with biopsy proven OSCC were enrolled in the study. cTNM staging was based on clinical examination and CT/MRI. Primary tumor excision along with neck dissection was done in all patients. Postoperatively pTNM staging was done and compared to cTNM. The clinical, radiological and histopathological lymph node status of patients were compared. Results: Among 80 patients, male to female ratio was 1.6:1. The mean of age was 50.2±10.2 years. The most common site in our center was the lateral border of the tongue. The total coincidence rate between clinical T-stage and pathological T-stage was 57.5%. On comparison between the clinical and pathological N-stage the total coincidence rate was 40%. The total coincidence rate between cTNM and pTNM was 35% and the p-value was insignificant (p>0.05). The sensitivity of CT/MRI for N-stage was 53.3% and specificity was 60% and positive predictive value (PPV) was 53.3% and negative predictive value (NPV) was 60%. Conclusion: Disparity between cTNM and pTNM of OSCC exits that could affect the treatment planning and prognosis.},
 year = {2021}
}

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