Incidence of Gastric Cancer in the Patients with Schizophrenia: A Meta-analysis

Jiacheng Gao; Yuhang Wang; Zirui Jia; Tingting Zhou; Xiangwen Zhang; Guo Zu

doi:doi:10.11648/j.ijg.20210502.12

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Incidence of Gastric Cancer in the Patients with Schizophrenia: A Meta-analysis

Jiacheng Gao, Yuhang Wang, Zirui Jia, Tingting Zhou, Xiangwen Zhang, Guo Zu

Published in International Journal of Gastroenterology (Volume 5, Issue 2)

Received: 9 July 2021 Accepted: 26 July 2021 Published: 2 August 2021

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Abstract

Background: Several studies have reported the incidence of gastric cancer (GC) in the patients with schizophrenia, but the incidence of GC in schizophrenia patients remains controversy. It is necessary to perform a meta-analysis to detect the incidence of GC in schizophrenia patients. Methods: We search the relevant articles from PubMed, EMBASE, Web of Science, the Cochrane Library and Chinese electronic databases. The incidence of GC in schizophrenia patients and heterogeneity were analyzed with STATA10.0 software. Results: Our meta-analysis included total 283,422 patients with schizophrenia and 1,024 patients with GC in nine articles. The incidence of GC in schizophrenia patients was 0.62% (95%CI: 0.005-0.008; P<0.001), but there is obvious heterogeneity (I²=98.7%). We next performed subgroup analysis to explore the incidence of GC in schizophrenia patients by gender and region. The GC incidence in male schizophrenia patients (0.28%, 95%CI: 0.001-0.003; P<0.001) was higher than that in female patients (0.23%, 95%CI: 0.002-0.004). In European countries, the GC incidence in schizophrenia patients (0.98%, 95%CI: 0.005-0.008) was higher than that in Asian countries (0.13%, 95%CI: 0.000-0.002; P<0.001). Conclusion: The incidence of GC in patients with schizophrenia was 0.62%. The GC incidence was higher in male and European countries schizophrenia patients, but large cohort studies are needed to confirm further.

Published in	International Journal of Gastroenterology (Volume 5, Issue 2)
DOI	10.11648/j.ijg.20210502.12
Page(s)	48-52
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Schizophrenia, Gastric Cancer, Incidence, Meta-analysis

References

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APA Style

Jiacheng Gao, Yuhang Wang, Zirui Jia, Tingting Zhou, Xiangwen Zhang, et al. (2021). Incidence of Gastric Cancer in the Patients with Schizophrenia: A Meta-analysis. International Journal of Gastroenterology, 5(2), 48-52. https://doi.org/10.11648/j.ijg.20210502.12

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ACS Style

Jiacheng Gao; Yuhang Wang; Zirui Jia; Tingting Zhou; Xiangwen Zhang, et al. Incidence of Gastric Cancer in the Patients with Schizophrenia: A Meta-analysis. Int. J. Gastroenterol. 2021, 5(2), 48-52. doi: 10.11648/j.ijg.20210502.12

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AMA Style

Jiacheng Gao, Yuhang Wang, Zirui Jia, Tingting Zhou, Xiangwen Zhang, et al. Incidence of Gastric Cancer in the Patients with Schizophrenia: A Meta-analysis. Int J Gastroenterol. 2021;5(2):48-52. doi: 10.11648/j.ijg.20210502.12

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@article{10.11648/j.ijg.20210502.12,
  author = {Jiacheng Gao and Yuhang Wang and Zirui Jia and Tingting Zhou and Xiangwen Zhang and Guo Zu},
  title = {Incidence of Gastric Cancer in the Patients with Schizophrenia: A Meta-analysis},
  journal = {International Journal of Gastroenterology},
  volume = {5},
  number = {2},
  pages = {48-52},
  doi = {10.11648/j.ijg.20210502.12},
  url = {https://doi.org/10.11648/j.ijg.20210502.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijg.20210502.12},
  abstract = {Background: Several studies have reported the incidence of gastric cancer (GC) in the patients with schizophrenia, but the incidence of GC in schizophrenia patients remains controversy. It is necessary to perform a meta-analysis to detect the incidence of GC in schizophrenia patients. Methods: We search the relevant articles from PubMed, EMBASE, Web of Science, the Cochrane Library and Chinese electronic databases. The incidence of GC in schizophrenia patients and heterogeneity were analyzed with STATA10.0 software. Results: Our meta-analysis included total 283,422 patients with schizophrenia and 1,024 patients with GC in nine articles. The incidence of GC in schizophrenia patients was 0.62% (95%CI: 0.005-0.008; P2=98.7%). We next performed subgroup analysis to explore the incidence of GC in schizophrenia patients by gender and region. The GC incidence in male schizophrenia patients (0.28%, 95%CI: 0.001-0.003; P<0.001) was higher than that in female patients (0.23%, 95%CI: 0.002-0.004). In European countries, the GC incidence in schizophrenia patients (0.98%, 95%CI: 0.005-0.008) was higher than that in Asian countries (0.13%, 95%CI: 0.000-0.002; P<0.001). Conclusion: The incidence of GC in patients with schizophrenia was 0.62%. The GC incidence was higher in male and European countries schizophrenia patients, but large cohort studies are needed to confirm further.},
 year = {2021}
}

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TY  - JOUR
T1  - Incidence of Gastric Cancer in the Patients with Schizophrenia: A Meta-analysis
AU  - Jiacheng Gao
AU  - Yuhang Wang
AU  - Zirui Jia
AU  - Tingting Zhou
AU  - Xiangwen Zhang
AU  - Guo Zu
Y1  - 2021/08/02
PY  - 2021
N1  - https://doi.org/10.11648/j.ijg.20210502.12
DO  - 10.11648/j.ijg.20210502.12
T2  - International Journal of Gastroenterology
JF  - International Journal of Gastroenterology
JO  - International Journal of Gastroenterology
SP  - 48
EP  - 52
PB  - Science Publishing Group
SN  - 2640-169X
UR  - https://doi.org/10.11648/j.ijg.20210502.12
AB  - Background: Several studies have reported the incidence of gastric cancer (GC) in the patients with schizophrenia, but the incidence of GC in schizophrenia patients remains controversy. It is necessary to perform a meta-analysis to detect the incidence of GC in schizophrenia patients. Methods: We search the relevant articles from PubMed, EMBASE, Web of Science, the Cochrane Library and Chinese electronic databases. The incidence of GC in schizophrenia patients and heterogeneity were analyzed with STATA10.0 software. Results: Our meta-analysis included total 283,422 patients with schizophrenia and 1,024 patients with GC in nine articles. The incidence of GC in schizophrenia patients was 0.62% (95%CI: 0.005-0.008; P2=98.7%). We next performed subgroup analysis to explore the incidence of GC in schizophrenia patients by gender and region. The GC incidence in male schizophrenia patients (0.28%, 95%CI: 0.001-0.003; P<0.001) was higher than that in female patients (0.23%, 95%CI: 0.002-0.004). In European countries, the GC incidence in schizophrenia patients (0.98%, 95%CI: 0.005-0.008) was higher than that in Asian countries (0.13%, 95%CI: 0.000-0.002; P<0.001). Conclusion: The incidence of GC in patients with schizophrenia was 0.62%. The GC incidence was higher in male and European countries schizophrenia patients, but large cohort studies are needed to confirm further.
VL  - 5
IS  - 2
ER  -

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Author Information

Jiacheng Gao

Gastrointestinal Surgery, The Dalian Municipal Central Hospital Affiliated of Dalian Medical University, Dalian, China
Yuhang Wang

Gastrointestinal Surgery, The Dalian Municipal Central Hospital Affiliated of Dalian Medical University, Dalian, China
Zirui Jia

Gastrointestinal Surgery, The Dalian Municipal Central Hospital Affiliated of Dalian Medical University, Dalian, China
Tingting Zhou

Department of Neurology, The First Affiliated Hospital of Dalian Medical University, Dalian, China
Xiangwen Zhang

Gastrointestinal Surgery, The Dalian Municipal Central Hospital Affiliated of Dalian Medical University, Dalian, China
Guo Zu

Gastrointestinal Surgery, The Dalian Municipal Central Hospital Affiliated of Dalian Medical University, Dalian, China

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APA Style

Jiacheng Gao, Yuhang Wang, Zirui Jia, Tingting Zhou, Xiangwen Zhang, et al. (2021). Incidence of Gastric Cancer in the Patients with Schizophrenia: A Meta-analysis. International Journal of Gastroenterology, 5(2), 48-52. https://doi.org/10.11648/j.ijg.20210502.12

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ACS Style

Jiacheng Gao; Yuhang Wang; Zirui Jia; Tingting Zhou; Xiangwen Zhang, et al. Incidence of Gastric Cancer in the Patients with Schizophrenia: A Meta-analysis. Int. J. Gastroenterol. 2021, 5(2), 48-52. doi: 10.11648/j.ijg.20210502.12

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AMA Style

Jiacheng Gao, Yuhang Wang, Zirui Jia, Tingting Zhou, Xiangwen Zhang, et al. Incidence of Gastric Cancer in the Patients with Schizophrenia: A Meta-analysis. Int J Gastroenterol. 2021;5(2):48-52. doi: 10.11648/j.ijg.20210502.12

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@article{10.11648/j.ijg.20210502.12,
  author = {Jiacheng Gao and Yuhang Wang and Zirui Jia and Tingting Zhou and Xiangwen Zhang and Guo Zu},
  title = {Incidence of Gastric Cancer in the Patients with Schizophrenia: A Meta-analysis},
  journal = {International Journal of Gastroenterology},
  volume = {5},
  number = {2},
  pages = {48-52},
  doi = {10.11648/j.ijg.20210502.12},
  url = {https://doi.org/10.11648/j.ijg.20210502.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijg.20210502.12},
  abstract = {Background: Several studies have reported the incidence of gastric cancer (GC) in the patients with schizophrenia, but the incidence of GC in schizophrenia patients remains controversy. It is necessary to perform a meta-analysis to detect the incidence of GC in schizophrenia patients. Methods: We search the relevant articles from PubMed, EMBASE, Web of Science, the Cochrane Library and Chinese electronic databases. The incidence of GC in schizophrenia patients and heterogeneity were analyzed with STATA10.0 software. Results: Our meta-analysis included total 283,422 patients with schizophrenia and 1,024 patients with GC in nine articles. The incidence of GC in schizophrenia patients was 0.62% (95%CI: 0.005-0.008; P2=98.7%). We next performed subgroup analysis to explore the incidence of GC in schizophrenia patients by gender and region. The GC incidence in male schizophrenia patients (0.28%, 95%CI: 0.001-0.003; P<0.001) was higher than that in female patients (0.23%, 95%CI: 0.002-0.004). In European countries, the GC incidence in schizophrenia patients (0.98%, 95%CI: 0.005-0.008) was higher than that in Asian countries (0.13%, 95%CI: 0.000-0.002; P<0.001). Conclusion: The incidence of GC in patients with schizophrenia was 0.62%. The GC incidence was higher in male and European countries schizophrenia patients, but large cohort studies are needed to confirm further.},
 year = {2021}
}

Copy | Download

TY  - JOUR
T1  - Incidence of Gastric Cancer in the Patients with Schizophrenia: A Meta-analysis
AU  - Jiacheng Gao
AU  - Yuhang Wang
AU  - Zirui Jia
AU  - Tingting Zhou
AU  - Xiangwen Zhang
AU  - Guo Zu
Y1  - 2021/08/02
PY  - 2021
N1  - https://doi.org/10.11648/j.ijg.20210502.12
DO  - 10.11648/j.ijg.20210502.12
T2  - International Journal of Gastroenterology
JF  - International Journal of Gastroenterology
JO  - International Journal of Gastroenterology
SP  - 48
EP  - 52
PB  - Science Publishing Group
SN  - 2640-169X
UR  - https://doi.org/10.11648/j.ijg.20210502.12
AB  - Background: Several studies have reported the incidence of gastric cancer (GC) in the patients with schizophrenia, but the incidence of GC in schizophrenia patients remains controversy. It is necessary to perform a meta-analysis to detect the incidence of GC in schizophrenia patients. Methods: We search the relevant articles from PubMed, EMBASE, Web of Science, the Cochrane Library and Chinese electronic databases. The incidence of GC in schizophrenia patients and heterogeneity were analyzed with STATA10.0 software. Results: Our meta-analysis included total 283,422 patients with schizophrenia and 1,024 patients with GC in nine articles. The incidence of GC in schizophrenia patients was 0.62% (95%CI: 0.005-0.008; P2=98.7%). We next performed subgroup analysis to explore the incidence of GC in schizophrenia patients by gender and region. The GC incidence in male schizophrenia patients (0.28%, 95%CI: 0.001-0.003; P<0.001) was higher than that in female patients (0.23%, 95%CI: 0.002-0.004). In European countries, the GC incidence in schizophrenia patients (0.98%, 95%CI: 0.005-0.008) was higher than that in Asian countries (0.13%, 95%CI: 0.000-0.002; P<0.001). Conclusion: The incidence of GC in patients with schizophrenia was 0.62%. The GC incidence was higher in male and European countries schizophrenia patients, but large cohort studies are needed to confirm further.
VL  - 5
IS  - 2
ER  -

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