Diagnostic Value of Dynamic Contrast-Enhanced MRI Combined with Molybdenum Target X-ray in Non Mass Enhanced Lesions of Breast

Jiao Wang; Zengkui Wang

doi:doi:10.11648/j.ijmi.20221004.11

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Diagnostic Value of Dynamic Contrast-Enhanced MRI Combined with Molybdenum Target X-ray in Non Mass Enhanced Lesions of Breast

Jiao Wang, Zengkui Wang

Published in International Journal of Medical Imaging (Volume 10, Issue 4)

Received: 25 September 2022 Accepted: 12 October 2022 Published: 24 October 2022

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Abstract

Background: Breast cancer occupies the first place in the incidence of female malignant tumors, and has a tendency of becoming younger, and the proportion of non-mass breast cancer in young people is higher. In non-mass like breast lesions (NMLE), which lack typical imaging and are rich in pathological forms, there is often misdiagnosed. It has become an urgent problem to select the correct imaging method, improve the diagnostic accuracy, increase the probability of breast preservation, and improve the quality of life and life span of patients. Objective: To investigate the differential value of the combination of dynamic contrast-enhanced (DCE) MRI and X-ray mammography in diagnosing benign and malignant breast lesions presented as non-mass-like enhancement (NMLE). Methods: A retrospective analysis was carried out on DCE-MRI and X-ray mammography data of 82 patients with NMLE confirmed by surgical pathology. Results: 1) Among the 82 cases of NMLE, 35 cases were benign masses and 47 cases were malignant tumors. 2) There were statistically significant differences between patients with NMLE in distribution, enhanced characteristics of lesions and ADC values; while there were no statistically significant differences in types of TIC. 3) The sensitivity, positive predictive value and negative predictive value of the combination of DCE- MRI and X-ray mammography to NMLE was increased. Conclusions: There are great values of the combination of DCE-MRI and X-ray mammography in diagnosing benign and malignant breast lesions presented as NMLE.

Published in	International Journal of Medical Imaging (Volume 10, Issue 4)
DOI	10.11648/j.ijmi.20221004.11
Page(s)	44-48
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Dynamic Contrast-Enhanced MRI, X-ray Mammography, Non-Mass-Like Enhancement, Differential Diagnosis, Combined Application

References

[1]	American College of Radiology. Breast imaging reporting and datasystem [M]. 4ed. Reston, VA: American College of Radiology, 2003: 1-114.
[2]	Edwards SD, Lipson JA, Ikeda DM, et al. Updates and revisions to the BI-RADS magnetic resonance imaging lexicon [J]. Magn Reson Imaging Clin N Am, 2013, 21 (3): 483-493.
[3]	Xiao L, Liuquan C, Mei L, et al. Comparative study of MRI, Molybdenum Target and Ultrasonography in the Diagnosis of Breast Nonmass-like Enhancement Lesions [J]. Chinese Journal of Medical Imaging, 2013, 21 (5): 336-340.
[4]	Heller SL, Moy L, Lavianlivi S, et al. Differentiation of malignant and benign breast lesions using magnetization transfer imaging and dynamic contrast-enhanced MRI [J]. J Magn Reson Imaging, 2013, 37 (1): 138-145.
[5]	Shao Z, Wang H, Li X, et al. Morphological distribution and internal enhancement architecture of contrast-enhanced magnetic resonance imaging in the diagnosis of non-mass-like breast lesions: a meta-analysis [J]. Breast J, 2013, 19 (3): 259-268.
[6]	Liang L, Dan Zh, Jing SH, et al. The clinical study of multimodal MRI in differentiating benign and malignant breast non mass enhancement lesions [J]. Journal of China Clinic Medical Imaging, 2020, 31 (1): 15-19.
[7]	Yabuuchi H, Matsuo Y, Kamitani T, et, al. Non-mass-like enhancement on contrast-enhanced breast MR imaging: lesion characterization using combination of dynamic contrast-enhanced and diffusion-weighted MR images [J]. Eur J Radiol, 2010, 75 (1): e126-132.
[8]	Lifang S, Xiaojuan L, Kaiyan Y, et al. Differential diagnosis of non mass lesions in mammography by dynamic enhanced MR [J]. Chinese Journal of Medical Imaging Technology, 2014, 30 (5): 728-732.
[9]	Aang Y, Xuehong X, Zhilong W, et al. Imaging differential diagnosis between idiopathic granulomatous mastitis and ductal carcinoma in situ [J]. Journal of Clinical Radiology, 2015, 34 (8): 1215-1218.
[10]	Newell D, Nie K, Chen JH, et al. Selection of diagnostic features on breast MRI to differentiate between malignant and benign lesions using computer-aided diagnosis: differences in lesions presenting as mass and non-mass-like enhancement [J]. Eur Radiol, 2010, 20 (4): 771-781.
[11]	Imamura T, Isomoto I, Sueyoshi E, et al. Diagnostic performance of ADC for Non-mass-like breast lesions on MR imaging [J]. Magn Reson Med Sci, 2010, 9 (4): 217-225.
[12]	Liu H, Peng W. MRI morphological classification of ductal carcinoma insitu (DCIS) correlating with different biological behavior [J]. Eur J Radiol, 2012, 81 (2): 214-217.
[13]	Thomassin-Naggara I, Salem C, Darai E, et al. Non-masslike enhancement on breast MRI: interpretation pearls [J]. J Radiol, 2009, 90 (3): 269-275.
[14]	Jansen SA, Fan X, Karczmar GS, et, al. DCEMRI of breast lesions: is kinetic analysis equally effective for both mass and nonmass-like enhancement? [J]. Med Phys, 2008, 35 (7): 3102-3109.
[15]	Cheng L, Bai Y, Zhang J, et, al. Optimization of apparent diffusion coefficient measured by diffusion-weighted MRI for diagnosis of breast lesions presenting as mass and non-mass-like enhancement [J]. Tumour Biol, 2013, 34 (3): 1537-1545.

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APA Style

Jiao Wang, Zengkui Wang. (2022). Diagnostic Value of Dynamic Contrast-Enhanced MRI Combined with Molybdenum Target X-ray in Non Mass Enhanced Lesions of Breast. International Journal of Medical Imaging, 10(4), 44-48. https://doi.org/10.11648/j.ijmi.20221004.11

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ACS Style

Jiao Wang; Zengkui Wang. Diagnostic Value of Dynamic Contrast-Enhanced MRI Combined with Molybdenum Target X-ray in Non Mass Enhanced Lesions of Breast. Int. J. Med. Imaging 2022, 10(4), 44-48. doi: 10.11648/j.ijmi.20221004.11

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AMA Style

Jiao Wang, Zengkui Wang. Diagnostic Value of Dynamic Contrast-Enhanced MRI Combined with Molybdenum Target X-ray in Non Mass Enhanced Lesions of Breast. Int J Med Imaging. 2022;10(4):44-48. doi: 10.11648/j.ijmi.20221004.11

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@article{10.11648/j.ijmi.20221004.11,
  author = {Jiao Wang and Zengkui Wang},
  title = {Diagnostic Value of Dynamic Contrast-Enhanced MRI Combined with Molybdenum Target X-ray in Non Mass Enhanced Lesions of Breast},
  journal = {International Journal of Medical Imaging},
  volume = {10},
  number = {4},
  pages = {44-48},
  doi = {10.11648/j.ijmi.20221004.11},
  url = {https://doi.org/10.11648/j.ijmi.20221004.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijmi.20221004.11},
  abstract = {Background: Breast cancer occupies the first place in the incidence of female malignant tumors, and has a tendency of becoming younger, and the proportion of non-mass breast cancer in young people is higher. In non-mass like breast lesions (NMLE), which lack typical imaging and are rich in pathological forms, there is often misdiagnosed. It has become an urgent problem to select the correct imaging method, improve the diagnostic accuracy, increase the probability of breast preservation, and improve the quality of life and life span of patients. Objective: To investigate the differential value of the combination of dynamic contrast-enhanced (DCE) MRI and X-ray mammography in diagnosing benign and malignant breast lesions presented as non-mass-like enhancement (NMLE). Methods: A retrospective analysis was carried out on DCE-MRI and X-ray mammography data of 82 patients with NMLE confirmed by surgical pathology. Results: 1) Among the 82 cases of NMLE, 35 cases were benign masses and 47 cases were malignant tumors. 2) There were statistically significant differences between patients with NMLE in distribution, enhanced characteristics of lesions and ADC values; while there were no statistically significant differences in types of TIC. 3) The sensitivity, positive predictive value and negative predictive value of the combination of DCE- MRI and X-ray mammography to NMLE was increased. Conclusions: There are great values of the combination of DCE-MRI and X-ray mammography in diagnosing benign and malignant breast lesions presented as NMLE.},
 year = {2022}
}

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TY  - JOUR
T1  - Diagnostic Value of Dynamic Contrast-Enhanced MRI Combined with Molybdenum Target X-ray in Non Mass Enhanced Lesions of Breast
AU  - Jiao Wang
AU  - Zengkui Wang
Y1  - 2022/10/24
PY  - 2022
N1  - https://doi.org/10.11648/j.ijmi.20221004.11
DO  - 10.11648/j.ijmi.20221004.11
T2  - International Journal of Medical Imaging
JF  - International Journal of Medical Imaging
JO  - International Journal of Medical Imaging
SP  - 44
EP  - 48
PB  - Science Publishing Group
SN  - 2330-832X
UR  - https://doi.org/10.11648/j.ijmi.20221004.11
AB  - Background: Breast cancer occupies the first place in the incidence of female malignant tumors, and has a tendency of becoming younger, and the proportion of non-mass breast cancer in young people is higher. In non-mass like breast lesions (NMLE), which lack typical imaging and are rich in pathological forms, there is often misdiagnosed. It has become an urgent problem to select the correct imaging method, improve the diagnostic accuracy, increase the probability of breast preservation, and improve the quality of life and life span of patients. Objective: To investigate the differential value of the combination of dynamic contrast-enhanced (DCE) MRI and X-ray mammography in diagnosing benign and malignant breast lesions presented as non-mass-like enhancement (NMLE). Methods: A retrospective analysis was carried out on DCE-MRI and X-ray mammography data of 82 patients with NMLE confirmed by surgical pathology. Results: 1) Among the 82 cases of NMLE, 35 cases were benign masses and 47 cases were malignant tumors. 2) There were statistically significant differences between patients with NMLE in distribution, enhanced characteristics of lesions and ADC values; while there were no statistically significant differences in types of TIC. 3) The sensitivity, positive predictive value and negative predictive value of the combination of DCE- MRI and X-ray mammography to NMLE was increased. Conclusions: There are great values of the combination of DCE-MRI and X-ray mammography in diagnosing benign and malignant breast lesions presented as NMLE.
VL  - 10
IS  - 4
ER  -

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Author Information

Jiao Wang

Department of Medical Technology, Cangzhou Medical College, Cangzhou, China
Zengkui Wang

Imaging Center, Cangzhou People’s Hospital, Cangzhou, China

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Plain Text BibTeX RIS

APA Style

Jiao Wang, Zengkui Wang. (2022). Diagnostic Value of Dynamic Contrast-Enhanced MRI Combined with Molybdenum Target X-ray in Non Mass Enhanced Lesions of Breast. International Journal of Medical Imaging, 10(4), 44-48. https://doi.org/10.11648/j.ijmi.20221004.11

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ACS Style

Jiao Wang; Zengkui Wang. Diagnostic Value of Dynamic Contrast-Enhanced MRI Combined with Molybdenum Target X-ray in Non Mass Enhanced Lesions of Breast. Int. J. Med. Imaging 2022, 10(4), 44-48. doi: 10.11648/j.ijmi.20221004.11

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AMA Style

Jiao Wang, Zengkui Wang. Diagnostic Value of Dynamic Contrast-Enhanced MRI Combined with Molybdenum Target X-ray in Non Mass Enhanced Lesions of Breast. Int J Med Imaging. 2022;10(4):44-48. doi: 10.11648/j.ijmi.20221004.11

Copy | Download

@article{10.11648/j.ijmi.20221004.11,
  author = {Jiao Wang and Zengkui Wang},
  title = {Diagnostic Value of Dynamic Contrast-Enhanced MRI Combined with Molybdenum Target X-ray in Non Mass Enhanced Lesions of Breast},
  journal = {International Journal of Medical Imaging},
  volume = {10},
  number = {4},
  pages = {44-48},
  doi = {10.11648/j.ijmi.20221004.11},
  url = {https://doi.org/10.11648/j.ijmi.20221004.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijmi.20221004.11},
  abstract = {Background: Breast cancer occupies the first place in the incidence of female malignant tumors, and has a tendency of becoming younger, and the proportion of non-mass breast cancer in young people is higher. In non-mass like breast lesions (NMLE), which lack typical imaging and are rich in pathological forms, there is often misdiagnosed. It has become an urgent problem to select the correct imaging method, improve the diagnostic accuracy, increase the probability of breast preservation, and improve the quality of life and life span of patients. Objective: To investigate the differential value of the combination of dynamic contrast-enhanced (DCE) MRI and X-ray mammography in diagnosing benign and malignant breast lesions presented as non-mass-like enhancement (NMLE). Methods: A retrospective analysis was carried out on DCE-MRI and X-ray mammography data of 82 patients with NMLE confirmed by surgical pathology. Results: 1) Among the 82 cases of NMLE, 35 cases were benign masses and 47 cases were malignant tumors. 2) There were statistically significant differences between patients with NMLE in distribution, enhanced characteristics of lesions and ADC values; while there were no statistically significant differences in types of TIC. 3) The sensitivity, positive predictive value and negative predictive value of the combination of DCE- MRI and X-ray mammography to NMLE was increased. Conclusions: There are great values of the combination of DCE-MRI and X-ray mammography in diagnosing benign and malignant breast lesions presented as NMLE.},
 year = {2022}
}

Copy | Download

TY  - JOUR
T1  - Diagnostic Value of Dynamic Contrast-Enhanced MRI Combined with Molybdenum Target X-ray in Non Mass Enhanced Lesions of Breast
AU  - Jiao Wang
AU  - Zengkui Wang
Y1  - 2022/10/24
PY  - 2022
N1  - https://doi.org/10.11648/j.ijmi.20221004.11
DO  - 10.11648/j.ijmi.20221004.11
T2  - International Journal of Medical Imaging
JF  - International Journal of Medical Imaging
JO  - International Journal of Medical Imaging
SP  - 44
EP  - 48
PB  - Science Publishing Group
SN  - 2330-832X
UR  - https://doi.org/10.11648/j.ijmi.20221004.11
AB  - Background: Breast cancer occupies the first place in the incidence of female malignant tumors, and has a tendency of becoming younger, and the proportion of non-mass breast cancer in young people is higher. In non-mass like breast lesions (NMLE), which lack typical imaging and are rich in pathological forms, there is often misdiagnosed. It has become an urgent problem to select the correct imaging method, improve the diagnostic accuracy, increase the probability of breast preservation, and improve the quality of life and life span of patients. Objective: To investigate the differential value of the combination of dynamic contrast-enhanced (DCE) MRI and X-ray mammography in diagnosing benign and malignant breast lesions presented as non-mass-like enhancement (NMLE). Methods: A retrospective analysis was carried out on DCE-MRI and X-ray mammography data of 82 patients with NMLE confirmed by surgical pathology. Results: 1) Among the 82 cases of NMLE, 35 cases were benign masses and 47 cases were malignant tumors. 2) There were statistically significant differences between patients with NMLE in distribution, enhanced characteristics of lesions and ADC values; while there were no statistically significant differences in types of TIC. 3) The sensitivity, positive predictive value and negative predictive value of the combination of DCE- MRI and X-ray mammography to NMLE was increased. Conclusions: There are great values of the combination of DCE-MRI and X-ray mammography in diagnosing benign and malignant breast lesions presented as NMLE.
VL  - 10
IS  - 4
ER  -

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