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The Effect Observation of Lianhua Qingwen Granule in the Adjuvant Treatment of Community Acquired Pneumonia (CAP)

Received: 12 April 2021    Accepted:     Published: 4 June 2021
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Abstract

Objective To observe the efficacy of Lianhua Qingwen Granule in the adjuvant treatment of community-acquired pneumonia (CAP). Methods From March 2018 to January 2020, adult patients with CAP who visited the internal medicine clinic of community health service center of Minzu University of China were divided by a random code list into two groups: the observation group (31cases), Lianhua Qingwen Granule orally combined with Levofloxacin intravenous drop, The control group (31 cases), Levofloxacin intravenous drop alonely. The cough symptom score, the cough visual simulation score (VAS), antipyretic time and X-ray chest shadow absorption were compared between the two groups to judge the curative effect. Measurement data were expressed as mean±standard deviation, and comparison used independent sample t test. Enumeration data were expressed as percentages, total effective rates were compared by χ2 tests. Results There were no statistically significant differences in baseline data, such as age, score of cough symptom before treatment between the two groups. Compared with the control group, cough symptom score and VAS of observation group decreased significantly [(2.45±1.312) point vs (3.61±1.476) point, P=0.002], [(3.68±1.973) point vs (4.84±1.753) point, P=0.017], antipyretic time was decreased significantly [(3.00 ±1.4814) day VS (4.842±1.5728) day, P=0.001], effective rate was increased significantly (87.1% VS 64.5%, P=0.038). Compliance: the rate of hospital transfer without medical advice was decreased significantly (6.45% VS 29.03% P=0.046). Conclusion Lianhua Qingwen Granule combined with levofloxacin has good efficacy and compliance in the treatment of CAP, and community doctors can choose it.

Published in Science Discovery (Volume 9, Issue 4)
DOI 10.11648/j.sd.20210904.15
Page(s) 155-159
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Community Acquired Pneumonia (CAP), Lianhua Qingwen Granule, Levofloxacin Injection, The Community Hospital, Compliance

References
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  • APA Style

    Xia Jianzhen, Shi Tongxia, Cao Wenli. (2021). The Effect Observation of Lianhua Qingwen Granule in the Adjuvant Treatment of Community Acquired Pneumonia (CAP). Science Discovery, 9(4), 155-159. https://doi.org/10.11648/j.sd.20210904.15

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    ACS Style

    Xia Jianzhen; Shi Tongxia; Cao Wenli. The Effect Observation of Lianhua Qingwen Granule in the Adjuvant Treatment of Community Acquired Pneumonia (CAP). Sci. Discov. 2021, 9(4), 155-159. doi: 10.11648/j.sd.20210904.15

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    AMA Style

    Xia Jianzhen, Shi Tongxia, Cao Wenli. The Effect Observation of Lianhua Qingwen Granule in the Adjuvant Treatment of Community Acquired Pneumonia (CAP). Sci Discov. 2021;9(4):155-159. doi: 10.11648/j.sd.20210904.15

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  • @article{10.11648/j.sd.20210904.15,
      author = {Xia Jianzhen and Shi Tongxia and Cao Wenli},
      title = {The Effect Observation of Lianhua Qingwen Granule in the Adjuvant Treatment of Community Acquired Pneumonia (CAP)},
      journal = {Science Discovery},
      volume = {9},
      number = {4},
      pages = {155-159},
      doi = {10.11648/j.sd.20210904.15},
      url = {https://doi.org/10.11648/j.sd.20210904.15},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sd.20210904.15},
      abstract = {Objective To observe the efficacy of Lianhua Qingwen Granule in the adjuvant treatment of community-acquired pneumonia (CAP). Methods From March 2018 to January 2020, adult patients with CAP who visited the internal medicine clinic of community health service center of Minzu University of China were divided by a random code list into two groups: the observation group (31cases), Lianhua Qingwen Granule orally combined with Levofloxacin intravenous drop, The control group (31 cases), Levofloxacin intravenous drop alonely. The cough symptom score, the cough visual simulation score (VAS), antipyretic time and X-ray chest shadow absorption were compared between the two groups to judge the curative effect. Measurement data were expressed as mean±standard deviation, and comparison used independent sample t test. Enumeration data were expressed as percentages, total effective rates were compared by χ2 tests. Results There were no statistically significant differences in baseline data, such as age, score of cough symptom before treatment between the two groups. Compared with the control group, cough symptom score and VAS of observation group decreased significantly [(2.45±1.312) point vs (3.61±1.476) point, P=0.002], [(3.68±1.973) point vs (4.84±1.753) point, P=0.017], antipyretic time was decreased significantly [(3.00 ±1.4814) day VS (4.842±1.5728) day, P=0.001], effective rate was increased significantly (87.1% VS 64.5%, P=0.038). Compliance: the rate of hospital transfer without medical advice was decreased significantly (6.45% VS 29.03% P=0.046). Conclusion Lianhua Qingwen Granule combined with levofloxacin has good efficacy and compliance in the treatment of CAP, and community doctors can choose it.},
     year = {2021}
    }
    

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  • TY  - JOUR
    T1  - The Effect Observation of Lianhua Qingwen Granule in the Adjuvant Treatment of Community Acquired Pneumonia (CAP)
    AU  - Xia Jianzhen
    AU  - Shi Tongxia
    AU  - Cao Wenli
    Y1  - 2021/06/04
    PY  - 2021
    N1  - https://doi.org/10.11648/j.sd.20210904.15
    DO  - 10.11648/j.sd.20210904.15
    T2  - Science Discovery
    JF  - Science Discovery
    JO  - Science Discovery
    SP  - 155
    EP  - 159
    PB  - Science Publishing Group
    SN  - 2331-0650
    UR  - https://doi.org/10.11648/j.sd.20210904.15
    AB  - Objective To observe the efficacy of Lianhua Qingwen Granule in the adjuvant treatment of community-acquired pneumonia (CAP). Methods From March 2018 to January 2020, adult patients with CAP who visited the internal medicine clinic of community health service center of Minzu University of China were divided by a random code list into two groups: the observation group (31cases), Lianhua Qingwen Granule orally combined with Levofloxacin intravenous drop, The control group (31 cases), Levofloxacin intravenous drop alonely. The cough symptom score, the cough visual simulation score (VAS), antipyretic time and X-ray chest shadow absorption were compared between the two groups to judge the curative effect. Measurement data were expressed as mean±standard deviation, and comparison used independent sample t test. Enumeration data were expressed as percentages, total effective rates were compared by χ2 tests. Results There were no statistically significant differences in baseline data, such as age, score of cough symptom before treatment between the two groups. Compared with the control group, cough symptom score and VAS of observation group decreased significantly [(2.45±1.312) point vs (3.61±1.476) point, P=0.002], [(3.68±1.973) point vs (4.84±1.753) point, P=0.017], antipyretic time was decreased significantly [(3.00 ±1.4814) day VS (4.842±1.5728) day, P=0.001], effective rate was increased significantly (87.1% VS 64.5%, P=0.038). Compliance: the rate of hospital transfer without medical advice was decreased significantly (6.45% VS 29.03% P=0.046). Conclusion Lianhua Qingwen Granule combined with levofloxacin has good efficacy and compliance in the treatment of CAP, and community doctors can choose it.
    VL  - 9
    IS  - 4
    ER  - 

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Author Information
  • Outpatient 1st Department, Community Hospital of Minzu University of China, Beijing, China

  • Outpatient 1st Department, Community Hospital of Minzu University of China, Beijing, China

  • Infection 1st Department, Beijing Geriatric Hospital, Beijing, China

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