Multidrug-resistant tuberculosis (MDR-TB) is a major threat to tuberculosis (TB) control, and a common occurrence among HIV-infected patients in Nigeria. MDR-TB represents TB simultaneously resistant to at least rifampicin and isoniazid. This study aimed to identify the risk factors for MDR-TB among HIV-infected patients from four Northwestern Nigeria states attending treatment in Aminu Kano Teaching Hospital. A hospital-based retrospective case-control study was conducted by reviewing the clinical records of HIV-infected patients tested for MDR-TB from January 2015 to January 2017. A total of 111 MDR-TB cases were obtained, with equal number (111) of randomly selected controls for this study. We used a descriptive statistical technique to obtain summary values for cases and controls. Variables that showed significant association in bivariate analysis were subjected to multivariable logistic analysis. The independent predictors for MDR-TB were Female Sex (AOR=48.26, 95%, Cl: 6.39-365.88), Rural Residence (AOR=4.09, 95%, Cl: 2.05-8.17) and Age (26-45 years) (AOR=1.34, 95%, Cl: 0.56-3.59). Factors such as; Currently Married, Not Currently Married, Previously Treated and Previously Untreated showed no statistical significance at p>0.05. This study identified Female Sex, Rural Residence, and Age (26-45 years) as risk factors for MDR-TB among HIV-infected patients in Northwestern Nigeria. We recommend a prospective study for further understanding of the clinical outcomes of TB treatment and disease.
| Published in | World Journal of Public Health (Volume 7, Issue 3) |
| DOI | 10.11648/j.wjph.20220703.14 |
| Page(s) | 119-123 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
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Copyright © The Author(s), 2024. Published by Science Publishing Group |
Multidrug-Resistant Tuberculosis (MDR-TB), HIV, Risk Factor, Nigeria
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APA Style
Egbenoma Andrew Aigboeghian, Simon Ikechukwu Enem, Preciousgift Orhue Isibor. (2022). Risk Factors for Multidrug-Resistant Tuberculosis (MDR-TB) Among Human Immunodeficiency Virus (HIV)-Infected Patients in Northwestern Nigeria. World Journal of Public Health, 7(3), 119-123. https://doi.org/10.11648/j.wjph.20220703.14
ACS Style
Egbenoma Andrew Aigboeghian; Simon Ikechukwu Enem; Preciousgift Orhue Isibor. Risk Factors for Multidrug-Resistant Tuberculosis (MDR-TB) Among Human Immunodeficiency Virus (HIV)-Infected Patients in Northwestern Nigeria. World J. Public Health 2022, 7(3), 119-123. doi: 10.11648/j.wjph.20220703.14
AMA Style
Egbenoma Andrew Aigboeghian, Simon Ikechukwu Enem, Preciousgift Orhue Isibor. Risk Factors for Multidrug-Resistant Tuberculosis (MDR-TB) Among Human Immunodeficiency Virus (HIV)-Infected Patients in Northwestern Nigeria. World J Public Health. 2022;7(3):119-123. doi: 10.11648/j.wjph.20220703.14
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Download@article{10.11648/j.wjph.20220703.14,
author = {Egbenoma Andrew Aigboeghian and Simon Ikechukwu Enem and Preciousgift Orhue Isibor},
title = {Risk Factors for Multidrug-Resistant Tuberculosis (MDR-TB) Among Human Immunodeficiency Virus (HIV)-Infected Patients in Northwestern Nigeria},
journal = {World Journal of Public Health},
volume = {7},
number = {3},
pages = {119-123},
doi = {10.11648/j.wjph.20220703.14},
url = {https://doi.org/10.11648/j.wjph.20220703.14},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.wjph.20220703.14},
abstract = {Multidrug-resistant tuberculosis (MDR-TB) is a major threat to tuberculosis (TB) control, and a common occurrence among HIV-infected patients in Nigeria. MDR-TB represents TB simultaneously resistant to at least rifampicin and isoniazid. This study aimed to identify the risk factors for MDR-TB among HIV-infected patients from four Northwestern Nigeria states attending treatment in Aminu Kano Teaching Hospital. A hospital-based retrospective case-control study was conducted by reviewing the clinical records of HIV-infected patients tested for MDR-TB from January 2015 to January 2017. A total of 111 MDR-TB cases were obtained, with equal number (111) of randomly selected controls for this study. We used a descriptive statistical technique to obtain summary values for cases and controls. Variables that showed significant association in bivariate analysis were subjected to multivariable logistic analysis. The independent predictors for MDR-TB were Female Sex (AOR=48.26, 95%, Cl: 6.39-365.88), Rural Residence (AOR=4.09, 95%, Cl: 2.05-8.17) and Age (26-45 years) (AOR=1.34, 95%, Cl: 0.56-3.59). Factors such as; Currently Married, Not Currently Married, Previously Treated and Previously Untreated showed no statistical significance at p>0.05. This study identified Female Sex, Rural Residence, and Age (26-45 years) as risk factors for MDR-TB among HIV-infected patients in Northwestern Nigeria. We recommend a prospective study for further understanding of the clinical outcomes of TB treatment and disease.},
year = {2022}
}
TY - JOUR T1 - Risk Factors for Multidrug-Resistant Tuberculosis (MDR-TB) Among Human Immunodeficiency Virus (HIV)-Infected Patients in Northwestern Nigeria AU - Egbenoma Andrew Aigboeghian AU - Simon Ikechukwu Enem AU - Preciousgift Orhue Isibor Y1 - 2022/09/14 PY - 2022 N1 - https://doi.org/10.11648/j.wjph.20220703.14 DO - 10.11648/j.wjph.20220703.14 T2 - World Journal of Public Health JF - World Journal of Public Health JO - World Journal of Public Health SP - 119 EP - 123 PB - Science Publishing Group SN - 2637-6059 UR - https://doi.org/10.11648/j.wjph.20220703.14 AB - Multidrug-resistant tuberculosis (MDR-TB) is a major threat to tuberculosis (TB) control, and a common occurrence among HIV-infected patients in Nigeria. MDR-TB represents TB simultaneously resistant to at least rifampicin and isoniazid. This study aimed to identify the risk factors for MDR-TB among HIV-infected patients from four Northwestern Nigeria states attending treatment in Aminu Kano Teaching Hospital. A hospital-based retrospective case-control study was conducted by reviewing the clinical records of HIV-infected patients tested for MDR-TB from January 2015 to January 2017. A total of 111 MDR-TB cases were obtained, with equal number (111) of randomly selected controls for this study. We used a descriptive statistical technique to obtain summary values for cases and controls. Variables that showed significant association in bivariate analysis were subjected to multivariable logistic analysis. The independent predictors for MDR-TB were Female Sex (AOR=48.26, 95%, Cl: 6.39-365.88), Rural Residence (AOR=4.09, 95%, Cl: 2.05-8.17) and Age (26-45 years) (AOR=1.34, 95%, Cl: 0.56-3.59). Factors such as; Currently Married, Not Currently Married, Previously Treated and Previously Untreated showed no statistical significance at p>0.05. This study identified Female Sex, Rural Residence, and Age (26-45 years) as risk factors for MDR-TB among HIV-infected patients in Northwestern Nigeria. We recommend a prospective study for further understanding of the clinical outcomes of TB treatment and disease. VL - 7 IS - 3 ER -
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