-
Immunoreactivity of the Body During the Surgical Treatment of Brain Tumors
Issue:
Volume 4, Issue 4, December 2020
Pages:
71-75
Received:
26 September 2020
Accepted:
13 October 2020
Published:
21 October 2020
Abstract: Background: The cells of the immune system are actively involved in the tumor development process and can either suppress or stimulate tumor growth. Objective: to determine the role and significance of immunological indications of patients with brain tumors of different histostructure before and after surgical treatment. Methods: The number of lymphocytes, neutrophilic granulocytes, and platelets was analyzed in 246 patients with brain tumors of various histostructures. Results: It was determined that there were significant fluctuations in the content of leukocytes in the blood of patients with brain tumors of various histogenesis. The largest number of leukocytes was observed in neuroectodermal and mesenchymal tumors. However, neuroepithelial tumors (pituitary adenomas) did not show a considerable increase in the number of leukocytes compared with that in healthy individuals. Conclusions: It is revealed that the determination of the immune response is an essential component of clinical examination. These immune response options allow to develop targeted immunotherapy. The determination of immunoreactivity for these options was determined to be clinically feasible. In addition, belonging to a particular group based on the immune status considerably determines the further course of the tumor process and the effectiveness of the surgical treatment of brain tumors.
Abstract: Background: The cells of the immune system are actively involved in the tumor development process and can either suppress or stimulate tumor growth. Objective: to determine the role and significance of immunological indications of patients with brain tumors of different histostructure before and after surgical treatment. Methods: The number of lymp...
Show More
-
Characteristics and Features of Electroencephalography (EEG) in Children with Epilepsy
Putu Tarita Susanti,
I Gusti Ngurah Made Suwarba,
Dewi Sutriani Mahalini
Issue:
Volume 4, Issue 4, December 2020
Pages:
76-81
Received:
14 October 2020
Accepted:
23 October 2020
Published:
4 November 2020
Abstract: Epilepsy is a manifestation of impaired brain function with various etiologies in the form of recurrent paroxysmal seizure symptoms. Epilepsy occurs mostly in children. Electroencephalography (EEG) is performed to observe epileptogenic foci, certain epilepsy syndromes, evaluate treatment, and determine prognosis. The purpose of this study is to determine the characteristics and features of EEG in pediatric patients with epilepsy at Sanglah General Hospital. This study is a retrospective descriptive observational study. The data was achieved from medical records of patients who had just been diagnosed with epilepsy at the Pediatric Clinic of Sanglah General Hospital during the periode of January 2017 to December 2019. There was a total of 204 new epilepsy cases, with the prevalence of 6.4 per 1000 population. The data consists of the men vs female (57.4% vs 42,6%) and the majority of patients age range between 1-5 years old (49%). The data consists of generalized epilepsy with motor tonic clonic onset (75.5%) and focal epilepsy with motor tonic onset (20.6%). EEG examination was abnormal in 55.4% of the cases and abnormalities was found in head CT scans (42.7%). The etiology of pediatrics with epilepsy which was unknown (52.5%). More than half of anti-epileptic drug therapy used a monotherapy of valproic acid (54.4%), and polytherapy therapy of valproic acid and carbamazepine (17.6%). Most of the children had good nutritional status (76%). The data showed that a history of neonatal seizures in was found in 17 cases (8.3%), while a family history of epilepsy was found ini 34 cases (16.7%). Conclution that pediatric epileptic patients present with a generalized type of epilepsy onset tonic-clonic motor with an unknown etiology. EEG images are mostly abnormal. On CT scans of the head, abnormalities were found in 42.7% of cases. Most of them received monotherapy with valproic acid.
Abstract: Epilepsy is a manifestation of impaired brain function with various etiologies in the form of recurrent paroxysmal seizure symptoms. Epilepsy occurs mostly in children. Electroencephalography (EEG) is performed to observe epileptogenic foci, certain epilepsy syndromes, evaluate treatment, and determine prognosis. The purpose of this study is to det...
Show More
-
The Value of Inter Ictal EEG in the Diagnosis of Epilepsy at the Clinical Neurophysiology Laboratory of FANN Teaching Hospital of Dakar
Michel-Arnaud Saphou Damon,
Franck-Ladys Banzouzi,
Anna Modji Basse,
Hilaire Ewodo Touna,
Marième-Soda Diop-Sene,
Fidélie Scholastique Ngoungoure Halima,
Prisca-Rolande Bassole,
Adjaratou Dieynabou Sow,
Lala Bouna Seck
Issue:
Volume 4, Issue 4, December 2020
Pages:
82-85
Received:
2 November 2020
Accepted:
17 November 2020
Published:
27 November 2020
Abstract: Introduction: The diagnosis of epilepsy is mainly based on clinical features. Electroencephalography (EEG) is mainly essential on classifying epilepsy and epileptic syndromes. Our purpose is to demonstrate EEG has a role in setting the diagnosis of epilepsy. Method: We have studied the EEG of 775 patients of all age-groups registered in the EEGs laboratory of Fann Teaching hospital from July 1st to November 15th 2018. We included all patients not previously known with epilepsy. The EEGs conclusion were taken from the digital database. We have split them into two groups EEG abnormal versus EEG normal. The statistical analyzes were made by Epi Info 7.2.3.1. Results: The median age was 14 years old. The patient age range was from 38 days to 86 years. Patients with abnormal EEG were at 38% of the total. After univariate study were significantly associated with an abnormal EEG patients who came for focal onset crisis (74%) and those who came for spasm (84%). All with status epilepticus had abnormal EEG. Patients with generalized crises had an abnormal EEG in 60% but that was not significant. Diagnosis seek by pediatrician was significantly associated abnormal EEG. Conclusion: EEG is a very affordable test which plays a key role on the diagnosis of epilepsy. It sensitivity is closely linked with the experience of the ordering physician. Broad awareness of epilepsy among healthcare professionals and the community would be an important step in improving patient’s management.
Abstract: Introduction: The diagnosis of epilepsy is mainly based on clinical features. Electroencephalography (EEG) is mainly essential on classifying epilepsy and epileptic syndromes. Our purpose is to demonstrate EEG has a role in setting the diagnosis of epilepsy. Method: We have studied the EEG of 775 patients of all age-groups registered in the EEGs la...
Show More
-
Juvenile Ocular Myasthenia Gravis: A Case Report
Ferry Yulianto,
I Gusti Ngurah Made Suwarba,
Dewi Sutriani Mahalini,
Anak Agung Mas Putrawati Triningrat,
Made Paramita Wijayati
Issue:
Volume 4, Issue 4, December 2020
Pages:
86-91
Received:
8 November 2020
Accepted:
19 November 2020
Published:
27 November 2020
Abstract: Myasthenia gravis is a chronic autoimmune disease of neuromuscular blockade, characterized by rapid fatigability of striated muscle. Estimated incidence has been reported at 1/200,000 to 1/1,000,000 worldwide, but its incidence in Indonesia is not clearly recorded. We report a rare case of juvenile ocular myasthenia gravis which is considered rare in child population. The objective of this case report is to describe the proper assessment of its clinical presentation. Patient is an eleven years old boy who had ptosis and opthalmoplegia on both sides for three weeks duration. Its complaint was exaggerated with sustained gaze on daily activities. Ptosis was triggered quickly after being induced by fixated upgaze without blinking and improved after ice pack was put on his eyelids for five minutes. However, his vision was preserved and no slurred speech, dysphagia or limb weakness on physical examination. Neostigmine test showed positive result and rapid nerve stimulation test also revealed withsignificant decrement on the affected eyelid muscles. No thymoma was seen on chest CT scan and thyroid function test was also normal. Hence the diagnosis was made and pyridostigmine was started for its medication. This report present a rare case of juvenile ocular myasthenia gravis. Early recognizing by some diagnostic modalities confirms its diagnosis so that treatment could be started to control the muscle weariness and improving patient's quality of life.
Abstract: Myasthenia gravis is a chronic autoimmune disease of neuromuscular blockade, characterized by rapid fatigability of striated muscle. Estimated incidence has been reported at 1/200,000 to 1/1,000,000 worldwide, but its incidence in Indonesia is not clearly recorded. We report a rare case of juvenile ocular myasthenia gravis which is considered rare ...
Show More
-
The Nutritional Profile Among Children with Epilepsy at Sanglah Hospital
Johanes Ari Cahyo Prabowo,
I Gusti Ngurah Made Suwarba,
Dewi Sutriani Mahalini
Issue:
Volume 4, Issue 4, December 2020
Pages:
92-97
Received:
30 November 2020
Accepted:
9 December 2020
Published:
16 December 2020
Abstract: One million people live with epilepsy in Indonesia. The using of antiepileptic drug for the long time can affect the nutritional and growth profile among children with epilepsy. The purpose of this study is to determine the characteristics of nutritional profile among children with epilepsy at Sanglah Hospital Denpasar. This study is an observational retrospective study using a descriptive design that examined the nutritional profile among hospitalized children with epilepsy at the pediatric neurology ward at Sanglah Hospital, Denpasar. This study was done retrospectively based on secondary data since January 1, 2017 until December 31, 2019, with 95 samples population were collected. The mean age of sample population was 5,4 years (SD±4.3) with majority samples were male 60 children (63.1%) and female were 35 children (36,9%). The majority of samples had general epilepsy 59 children (62.1%), followed by focal epilepsy 23 children (24.2%) and general combined focal epilepsy 13 children (13.7%). In this study, the most common etiology of epilepsy were idiopathic 53 children (55.8%), followed by structural 30 children (31.6%), infection 8 children (8.4%), immunology and metabolic 4 children (4.2%). The most of sample population had normal nutritional status based on waterlow method (weight for height) was 55,4% and height for age was 74,7%. However, there were increasing number of overweight/obesity was 14 children (14,7%) with history of prolonged anti epileptic drug more than 12 month that using phenobarbital, phenytoin, and valproic acid for medication. The short stature was noted among 24 children (25,3%) of samples, with history of phenobarbital, phenytoin and carbamazepine medication. Sample population with moderate of protein energy malnutrition was 8 children (8.4%) with dysfunction of oromotor. We conclude that almost children with epilepsy at Sanglah hospital had normal nutritional status and height stature. However regular follow up of antropometric status and diagnostic serum calcium, and folic acid should be done for early detection of overweight and obesity along with short stature.
Abstract: One million people live with epilepsy in Indonesia. The using of antiepileptic drug for the long time can affect the nutritional and growth profile among children with epilepsy. The purpose of this study is to determine the characteristics of nutritional profile among children with epilepsy at Sanglah Hospital Denpasar. This study is an observation...
Show More
