Abstract: Our study focused on “Extraction identification and characterization of saponins from the plant Myrica salicifolia Hochst. ex. A. Rich and molluscicidal activity test in vitro". The objective of this study is to extract the natural substances present in the different parts (leaves, bark of the stem and roots); isolate the saponins, characterize them by chromatography and determine the lethal dose of the saponins isolated against aquatic molluscs. After the analyzes, the Malacology laboratory of the LWIRO Natural Sciences Research Center (CRSN / LWIRO) took place in the Democratic Republic of Congo in the Kabare Territory. Phytochemical screening has enabled us to observe that saponins, quinones, phenols, lipoids, glycosides, terpenoids, tannoids, flavonoids, and alkaloids are in high concentration while steroids are moderately concentrated in the different parts of the plant. The thin layer chromatography of the saponins shows that the plant contains steroidal and triterpene saponins. The Myrica salicifolia Hochst plant. ex. A. Rich has molluscicidal activity, it can be used in the fight against molluscs Biomphalaria pfeifferi and Lymnaea natalensis intermediate hosts of bilharziasis and fascioliosis. The lethal doses (LD50) of the saponin extracts from the bark of the roots and stems were 0.016 and 0.018 mg / mL respectively for Biomphalaria pfeifferi and 0.022 and 0.021 mg / mL for Lymnaea natalensis.Abstract: Our study focused on “Extraction identification and characterization of saponins from the plant Myrica salicifolia Hochst. ex. A. Rich and molluscicidal activity test in vitro". The objective of this study is to extract the natural substances present in the different parts (leaves, bark of the stem and roots); isolate the saponins, characterize the...Show More
Abstract: Acetylcysteine (ACC) helps people with pulmonary fibrosis and it is preferred treatment for the often deadly adult respiratory distress syndrome. ACC is a precursor in the formation of the glutathione antioxidant in the body. Compounds of zinc (II) and iron (II) with ACC and mucolytic medications play an important role in medical practice for the prevention of respiratory diseases. The present article is about determining the embryotoxicity of the new coordination compounds of Zincas and Feras, which are synthesized by the interaction of zinc (II) and iron (II) sulfates with acetylcysteine in an aqueous solution and have mucolytic properties in relation to diseases, bronchial asthma with a predominance of an infectious-dependent component of the course, chronic asthmatic bronchitis and chronic obstructive bronchitis. Daily administration of a feed or a high dose of 0.60 ml / kg inside the gastric suspension for 3 weeks to pregnant rats and the result of observation of the 13th week of life did not have a marked effect on the fetal development process. With the introduction of Feras and Zincas in a therapeutic dose for 1-3 weeks of pregnancy, the death of rat pups in the first month of life was comparable with the control values. The physical development of the offspring proceeded without any deviations from the norm. All pups were born normal, responded to external irritants well, with а good appetite and led an active lifestyle.Abstract: Acetylcysteine (ACC) helps people with pulmonary fibrosis and it is preferred treatment for the often deadly adult respiratory distress syndrome. ACC is a precursor in the formation of the glutathione antioxidant in the body. Compounds of zinc (II) and iron (II) with ACC and mucolytic medications play an important role in medical practice for the p...Show More
