In Vitro Cytotoxic Activity Toward Anticancer and Antimicrobial of Azadirachta Indica, Aegle Marmelos, Ocimum Sanctum and Withania Somnifera Extracts
Rajeev Nema,
Sarita Khare
Issue:
Volume 4, Issue 2, December 2020
Pages:
40-46
Received:
31 May 2019
Accepted:
17 September 2020
Published:
30 September 2020
Abstract: Background: Resistance to treatment represents the ‘big’ problem and the considerable improvement in survival rates still remains a researcher’s dream. Thus, continued research efforts are required to make treatments more personalized, to minimize side effects and improve overall survival and to also have an insight in toxico-genomics. Indeed proof of facts about medicinal plants worldwide and rich Indian medicinal flora, Objective: in the present investigation attempts to evaluate antimicrobials and anticancer therapeutic properties of isolated constituents from Withania somnifera (ASHWANGANDHA) Part Used Leaves, Aegle marmeleos (BEL) Part Used Leaves, Azadirachta indica (NEEM) Part Used Leaves, Ocimum sanctum (TULASI) Part Used Leaves, Method: Hydro alcoholic (1:1) Extracts were evaluated against cancer cell lines i.e. A549 (Lung carcinoma), PA-1 (Ovarian cancer) and MCF-7 (Breast cancer), with standard as Doxorubicin. Moreover the antimicrobial activity on Staphylococcus aureus, Bacillus coagulans and one Gram-negative—Escherichia coli, human pathogenic bacteria; and three fungal strains—Aspergillus niger, Tricoderma viride and Fusarium oxysporum. Result: The results showed significant association of phytochemicals on inhibition of test bacteria and fungi with significant p value p< 0.05, except For Tricoderma viride No Association Was Found P>0.05.
Abstract: Background: Resistance to treatment represents the ‘big’ problem and the considerable improvement in survival rates still remains a researcher’s dream. Thus, continued research efforts are required to make treatments more personalized, to minimize side effects and improve overall survival and to also have an insight in toxico-genomics. Indeed proof...
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The Effect of Honeybee (Apismellifera) Pollination in Enhancing Yield of Nigella sativa (Darbera Variety) in the High Land of Bale
Bekele Tesfaye,
Temaro Gelgelu,
Wodimu Lelisa
Issue:
Volume 4, Issue 2, December 2020
Pages:
47-51
Received:
14 November 2020
Accepted:
26 November 2020
Published:
16 December 2020
Abstract: Pollination is an essential process in the production of seed plants, it results in a genetically diverse production of offspring and its role is not well understood and appreciated in the local farming system. This study was conducted to evaluate the effect of honeybees pollination on Black cumin seed yield and yield related parameters at Sinana Agricultural Research center at on-station. The study had three experiment; these includes plots caged with honeybees (T1), plots caged without honeybees (T2) and open pollinated plots (T3). All collected data were analyzed using One-way-Analysis of Variance (ANOVA). In the study seven species of insects were identified as Nigella sativa visitors or pollinators with the most frequent visitors were honeybees at 11:30 am time and minimum at 3:00 pm on open pollinated plot. There were no significant different (P>0.05) on Date of blooming, Date of flowering, Flowering period, Primary and secondary branches among the three treatments. Whereas, there were a significant difference (P<0.05) on shading time, Number of capsule, Thousand kernel and total seed yield per hector. In general the present study showed that the highest seed yield/hector was achieved from crops caged with honeybees (20.20Qt/ha) and followed by open pollinated crop (17.54Qt/ha). The result also revealed that about 30.84% of seed yield advantage of Nigella sativa pollinated by honeybees over control/un pollinated by any insect. From this result it was concluded that visits of honeybees at flowering time of Nigella sativa have very helpful in boosting seed yield and yield related components of this crop.
Abstract: Pollination is an essential process in the production of seed plants, it results in a genetically diverse production of offspring and its role is not well understood and appreciated in the local farming system. This study was conducted to evaluate the effect of honeybees pollination on Black cumin seed yield and yield related parameters at Sinana A...
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