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Environmental Factors in Etiology of Gastric Cancer

Received: 30 August 2015    Accepted: 16 September 2015    Published: 26 September 2015
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Abstract

Among all the cancers Gastric cancer has been reported to be a highly prevalent malignancy In Kashmir valley, constitutes about 30%-40% of all malignancies. Cancer is consistently considered as significant environmental issue besides other etiological factors. In our study the incidence ratio among genders remained 3:1(male to female). More incidents were found in 60-64 years of age, 34.5% patients reported weight loss and the weight difference was about 10kg from stage I to Stage IV, 62% of the patients were illiterate, 59.5% of patients were from poor and middle class and 51% patients had faced the Water pollution. Major portion 53 %of patients belongs to farmers& house wives among these 38.6%, 12.2%, 8.4%, 21.6%& 18.8% had exposure to Pesticides/insecticides, Fungicides, Chemicals, Fertilizer, Manure respectively. At the time of diagnosis patients presented with multiple symptoms like dyspepsia 76.5%, loss of appetite 35.5% and vomiting 42.0%. On physical examination, anaemia was the most common sign and was present in 163 81.5%, ascites was 11.1%, epigastric mass in 9.9% Regarding distribution of cancer within the stomach, distal stomach was involved in 45.5%, proximal stomach in 42.0% of patients; Middle stomach and Whole stomach were involved in 6.0% each. Among the common symptom, ulceroproliferative type was seen in 35.5%, ulcerative lesions were 30% and infiltrative were in 7.0 %.Various perceptible effects during our study provides significant evidence to conclude that in gastric cancer etiology, environment plays an important role.

Published in Advances in Biochemistry (Volume 3, Issue 5)
DOI 10.11648/j.ab.20150305.11
Page(s) 51-56
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Gastric Cancer, Environmental Pollution, Occupation, Farming, Socio-demographic Profile, Clinical Presentation

References
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Cite This Article
  • APA Style

    Showkat Ahmad Bhat, Manzoor R. Mir, Sabhiya Majid, Muneeb U. Rehman, Sonallah Kuchy, et al. (2015). Environmental Factors in Etiology of Gastric Cancer. Advances in Biochemistry, 3(5), 51-56. https://doi.org/10.11648/j.ab.20150305.11

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    ACS Style

    Showkat Ahmad Bhat; Manzoor R. Mir; Sabhiya Majid; Muneeb U. Rehman; Sonallah Kuchy, et al. Environmental Factors in Etiology of Gastric Cancer. Adv. Biochem. 2015, 3(5), 51-56. doi: 10.11648/j.ab.20150305.11

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    AMA Style

    Showkat Ahmad Bhat, Manzoor R. Mir, Sabhiya Majid, Muneeb U. Rehman, Sonallah Kuchy, et al. Environmental Factors in Etiology of Gastric Cancer. Adv Biochem. 2015;3(5):51-56. doi: 10.11648/j.ab.20150305.11

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  • @article{10.11648/j.ab.20150305.11,
      author = {Showkat Ahmad Bhat and Manzoor R. Mir and Sabhiya Majid and Muneeb U. Rehman and Sonallah Kuchy and Bilal Ahmad Sheikh and Ishraq Husain and Bhudev C. Das},
      title = {Environmental Factors in Etiology of Gastric Cancer},
      journal = {Advances in Biochemistry},
      volume = {3},
      number = {5},
      pages = {51-56},
      doi = {10.11648/j.ab.20150305.11},
      url = {https://doi.org/10.11648/j.ab.20150305.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ab.20150305.11},
      abstract = {Among all the cancers Gastric cancer has been reported to be a highly prevalent malignancy In Kashmir valley, constitutes about 30%-40% of all malignancies. Cancer is consistently considered as significant environmental issue besides other etiological factors. In our study the incidence ratio among genders remained 3:1(male to female). More incidents were found in 60-64 years of age, 34.5% patients reported weight loss and the weight difference was about 10kg from stage I to Stage IV, 62% of the patients were illiterate, 59.5% of patients were from poor and middle class and 51% patients had faced the Water pollution. Major portion 53 %of patients belongs to farmers& house wives among these 38.6%, 12.2%, 8.4%, 21.6%& 18.8% had exposure to Pesticides/insecticides, Fungicides, Chemicals, Fertilizer, Manure respectively. At the time of diagnosis patients presented with multiple symptoms like dyspepsia 76.5%, loss of appetite 35.5% and vomiting 42.0%. On physical examination, anaemia was the most common sign and was present in 163 81.5%, ascites was 11.1%, epigastric mass in 9.9% Regarding distribution of cancer within the stomach, distal stomach was involved in 45.5%, proximal stomach in 42.0% of patients; Middle stomach and Whole stomach were involved in 6.0% each. Among the common symptom, ulceroproliferative type was seen in 35.5%, ulcerative lesions were 30% and infiltrative were in 7.0 %.Various perceptible effects during our study provides significant evidence to conclude that in gastric cancer etiology, environment plays an important role.},
     year = {2015}
    }
    

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  • TY  - JOUR
    T1  - Environmental Factors in Etiology of Gastric Cancer
    AU  - Showkat Ahmad Bhat
    AU  - Manzoor R. Mir
    AU  - Sabhiya Majid
    AU  - Muneeb U. Rehman
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    AU  - Bilal Ahmad Sheikh
    AU  - Ishraq Husain
    AU  - Bhudev C. Das
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    PY  - 2015
    N1  - https://doi.org/10.11648/j.ab.20150305.11
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    JF  - Advances in Biochemistry
    JO  - Advances in Biochemistry
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    EP  - 56
    PB  - Science Publishing Group
    SN  - 2329-0862
    UR  - https://doi.org/10.11648/j.ab.20150305.11
    AB  - Among all the cancers Gastric cancer has been reported to be a highly prevalent malignancy In Kashmir valley, constitutes about 30%-40% of all malignancies. Cancer is consistently considered as significant environmental issue besides other etiological factors. In our study the incidence ratio among genders remained 3:1(male to female). More incidents were found in 60-64 years of age, 34.5% patients reported weight loss and the weight difference was about 10kg from stage I to Stage IV, 62% of the patients were illiterate, 59.5% of patients were from poor and middle class and 51% patients had faced the Water pollution. Major portion 53 %of patients belongs to farmers& house wives among these 38.6%, 12.2%, 8.4%, 21.6%& 18.8% had exposure to Pesticides/insecticides, Fungicides, Chemicals, Fertilizer, Manure respectively. At the time of diagnosis patients presented with multiple symptoms like dyspepsia 76.5%, loss of appetite 35.5% and vomiting 42.0%. On physical examination, anaemia was the most common sign and was present in 163 81.5%, ascites was 11.1%, epigastric mass in 9.9% Regarding distribution of cancer within the stomach, distal stomach was involved in 45.5%, proximal stomach in 42.0% of patients; Middle stomach and Whole stomach were involved in 6.0% each. Among the common symptom, ulceroproliferative type was seen in 35.5%, ulcerative lesions were 30% and infiltrative were in 7.0 %.Various perceptible effects during our study provides significant evidence to conclude that in gastric cancer etiology, environment plays an important role.
    VL  - 3
    IS  - 5
    ER  - 

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Author Information
  • Division of Veterinary Biochemistry, Faculty of Veterinary Sciences & Animal Husbandry (F. V. Sc & AH), Sher-e-Kashmir University of Agricultural Sciences & Technology Kashmir (SKUAST-K), Shuhama, Alustang, Srinagar, Jammu & Kashmir, India

  • Division of Veterinary Biochemistry, Faculty of Veterinary Sciences & Animal Husbandry (F. V. Sc & AH), Sher-e-Kashmir University of Agricultural Sciences & Technology Kashmir (SKUAST-K), Shuhama, Alustang, Srinagar, Jammu & Kashmir, India

  • Department of Biochemistry Govt. Medical College Srinagar, Srinagar, Jammu & Kashmir, India

  • Division of Veterinary Biochemistry, Faculty of Veterinary Sciences & Animal Husbandry (F. V. Sc & AH), Sher-e-Kashmir University of Agricultural Sciences & Technology Kashmir (SKUAST-K), Shuhama, Alustang, Srinagar, Jammu & Kashmir, India

  • Department of Oncology, Govt. Medical College Srinagar, Srinagar, Jammu & Kashmir, India

  • Division of Veterinary Biochemistry, Faculty of Veterinary Sciences & Animal Husbandry (F. V. Sc & AH), Sher-e-Kashmir University of Agricultural Sciences & Technology Kashmir (SKUAST-K), Shuhama, Alustang, Srinagar, Jammu & Kashmir, India

  • Division of Veterinary Biochemistry, Faculty of Veterinary Sciences & Animal Husbandry (F. V. Sc & AH), Sher-e-Kashmir University of Agricultural Sciences & Technology Kashmir (SKUAST-K), Shuhama, Alustang, Srinagar, Jammu & Kashmir, India

  • Amity Institute of Molecular Medicine & Stem Cell Research (AIMMSCR), Amity University Uttar Pradesh Campus, Delhi, India

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