Gonads and adrenal glands are the primary organs for the production of steroid hormones in mammals. Steroid hormones play important roles in development and are essential for the maintenance of homeostasis during adult life. To supply sufficient amounts of hormones, gonads and adrenal glands maintain their functions by replenishment of steroidogenic cells. It has been hypothesized that stem/progenitor cells of steroidogenic cells are important for this phenomenon. In fact, such cells have been recently identified in gonads and adrenal glands. However, steroid hormone production decreases progressively with age, causing problems such as menopausal disorders in women. Although steroid hormones are administered to these patients, induction of steroidogenic cells from stem cells is a potential strategy to prevent menopausal disorders. Here, we review the current knowledge on stem cells that replenish steroid hormone-producing cells in the gonads and adrenal glands. We also discuss induction of steroidogenic cells from stem cells derived from non-steroidogenic organs.
| DOI | 10.11648/j.ajls.s.2015030302.21 |
| Published in |
American Journal of Life Sciences (Volume 3, Issue 3-2, May 2015)
This article belongs to the Special Issue Biology and Medicine of Peptide and Steroid Hormones |
| Page(s) | 58-64 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2024. Published by Science Publishing Group |
Steroid Hormone, Stem Cell, Adrenal, Testis, Ovary
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APA Style
Takashi Yazawa, Yoshitaka Imamichi, Kaoru Miyamoto, Junsuke Uwada, Md Rafiqul Islam Khan, et al. (2015). Overviews of Stem Cells for Gonadal and Adrenal Steroidogenic Cells. American Journal of Life Sciences, 3(3-2), 58-64. https://doi.org/10.11648/j.ajls.s.2015030302.21
ACS Style
Takashi Yazawa; Yoshitaka Imamichi; Kaoru Miyamoto; Junsuke Uwada; Md Rafiqul Islam Khan, et al. Overviews of Stem Cells for Gonadal and Adrenal Steroidogenic Cells. Am. J. Life Sci. 2015, 3(3-2), 58-64. doi: 10.11648/j.ajls.s.2015030302.21
AMA Style
Takashi Yazawa, Yoshitaka Imamichi, Kaoru Miyamoto, Junsuke Uwada, Md Rafiqul Islam Khan, et al. Overviews of Stem Cells for Gonadal and Adrenal Steroidogenic Cells. Am J Life Sci. 2015;3(3-2):58-64. doi: 10.11648/j.ajls.s.2015030302.21
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Download@article{10.11648/j.ajls.s.2015030302.21,
author = {Takashi Yazawa and Yoshitaka Imamichi and Kaoru Miyamoto and Junsuke Uwada and Md Rafiqul Islam Khan and Takanobu Taniguchi},
title = {Overviews of Stem Cells for Gonadal and Adrenal Steroidogenic Cells},
journal = {American Journal of Life Sciences},
volume = {3},
number = {3-2},
pages = {58-64},
doi = {10.11648/j.ajls.s.2015030302.21},
url = {https://doi.org/10.11648/j.ajls.s.2015030302.21},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajls.s.2015030302.21},
abstract = {Gonads and adrenal glands are the primary organs for the production of steroid hormones in mammals. Steroid hormones play important roles in development and are essential for the maintenance of homeostasis during adult life. To supply sufficient amounts of hormones, gonads and adrenal glands maintain their functions by replenishment of steroidogenic cells. It has been hypothesized that stem/progenitor cells of steroidogenic cells are important for this phenomenon. In fact, such cells have been recently identified in gonads and adrenal glands. However, steroid hormone production decreases progressively with age, causing problems such as menopausal disorders in women. Although steroid hormones are administered to these patients, induction of steroidogenic cells from stem cells is a potential strategy to prevent menopausal disorders. Here, we review the current knowledge on stem cells that replenish steroid hormone-producing cells in the gonads and adrenal glands. We also discuss induction of steroidogenic cells from stem cells derived from non-steroidogenic organs.},
year = {2015}
}
TY - JOUR T1 - Overviews of Stem Cells for Gonadal and Adrenal Steroidogenic Cells AU - Takashi Yazawa AU - Yoshitaka Imamichi AU - Kaoru Miyamoto AU - Junsuke Uwada AU - Md Rafiqul Islam Khan AU - Takanobu Taniguchi Y1 - 2015/05/06 PY - 2015 N1 - https://doi.org/10.11648/j.ajls.s.2015030302.21 DO - 10.11648/j.ajls.s.2015030302.21 T2 - American Journal of Life Sciences JF - American Journal of Life Sciences JO - American Journal of Life Sciences SP - 58 EP - 64 PB - Science Publishing Group SN - 2328-5737 UR - https://doi.org/10.11648/j.ajls.s.2015030302.21 AB - Gonads and adrenal glands are the primary organs for the production of steroid hormones in mammals. Steroid hormones play important roles in development and are essential for the maintenance of homeostasis during adult life. To supply sufficient amounts of hormones, gonads and adrenal glands maintain their functions by replenishment of steroidogenic cells. It has been hypothesized that stem/progenitor cells of steroidogenic cells are important for this phenomenon. In fact, such cells have been recently identified in gonads and adrenal glands. However, steroid hormone production decreases progressively with age, causing problems such as menopausal disorders in women. Although steroid hormones are administered to these patients, induction of steroidogenic cells from stem cells is a potential strategy to prevent menopausal disorders. Here, we review the current knowledge on stem cells that replenish steroid hormone-producing cells in the gonads and adrenal glands. We also discuss induction of steroidogenic cells from stem cells derived from non-steroidogenic organs. VL - 3 IS - 3-2 ER -
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