Physical, Thermal and Spectroscopic Studies of Biofield Treated p-Chlorobenzonitrile
Science Journal of Chemistry
Volume 3, Issue 6, December 2015, Pages: 84-90
Received: Sep. 19, 2015; Accepted: Sep. 30, 2015; Published: Oct. 16, 2015
Views 6067      Downloads 132
Mahendra Kumar Trivedi, Trivedi Global Inc., Henderson, USA
Alice Branton, Trivedi Global Inc., Henderson, USA
Dahryn Trivedi, Trivedi Global Inc., Henderson, USA
Gopal Nayak, Trivedi Global Inc., Henderson, USA
Ragini Singh, Trivedi Science Research Laboratory Pvt. Ltd., Hall-A, Chinar Mega Mall, Chinar Fortune City, Hoshangabad Rd., Bhopal, Madhya Pradesh, India
Snehasis Jana, Trivedi Science Research Laboratory Pvt. Ltd., Hall-A, Chinar Mega Mall, Chinar Fortune City, Hoshangabad Rd., Bhopal, Madhya Pradesh, India
Article Tools
Follow on us
Para-chlorobenzonitrile (p-CBN) is widely used as a chemical intermediate in the manufacturing of dyes, medicines, and pesticides, however; sometimes it may cause runaway reactions at high temperatures. The current study was designed to evaluate the impact of biofield energy treatment on the physical, thermal, and spectroscopic properties of p-CBN. The analysis was done by dividing the p-CBN samples into two groups that served as control and treated. The treated group received Mr. Trivedi’s biofield treatment. Subsequently, the control and treated samples were evaluated using various analytical techniques such as X-ray diffraction (XRD), surface area analyser, differential scanning calorimetry (DSC), thermogravimetric analysis (TGA), Fourier-transform infrared (FT-IR) and UV-visible (UV-Vis) spectroscopy. The XRD results showed an increase in the crystallite size (66.18 nm) of the treated sample as compared to the control sample (53.63 nm). The surface area analysis of the treated sample also showed 14.19% decrease in the surface area as compared to control. Furthermore, DSC analysis results showed that the latent heat of fusion of the treated p-CBN increased considerably by 5.94% as compared to control. However, the melting temperature of the treated sample did not show any considerable change from the control sample. Besides, TGA/DTG studies showed that Tmax (the temperature at which the sample lost its maximum weight) was increased by 5.22% along with an increase in its onset of thermal decomposition temperature i.e. 96.80°C in the biofield treated p-CBN as compared to the control sample (84.65°C). This indicates that the thermal stability of treated p-CBN sample might increase as compared to the control sample. However, no change was found in the FT-IR and UV-Vis spectroscopic character of the treated p-CBN as compared to the control. These findings suggest that the biofield treatment significantly altered the physical and thermal properties of p-CBN, which could make it more useful as a chemical intermediate.
Biofield Energy Treatment, Para-Chlorobenzonitrile, X-ray Diffraction Study, Surface Area Analyzer, Differential Scanning Calorimetry, Thermogravimetric Analysis
To cite this article
Mahendra Kumar Trivedi, Alice Branton, Dahryn Trivedi, Gopal Nayak, Ragini Singh, Snehasis Jana, Physical, Thermal and Spectroscopic Studies of Biofield Treated p-Chlorobenzonitrile, Science Journal of Chemistry. Vol. 3, No. 6, 2015, pp. 84-90. doi: 10.11648/j.sjc.20150306.11
Fabiani ME (1999) Angiotensin receptor subtypes: Novel target for cardiovascular therapy. Drug News Perspect 12: 207-216.
Tucker TJ, Sisko JT, Tynebor RM, Williams TM, Felock PJ, et al. (2008) Discovery of 3-{5-[(6-amino- 1H-pyrazolo[3,4-b]pyridine-3-yl)methoxy]-2- chlorophenoxy} - 5-chlorobenzonitrile (MK-4965): A potent, orally bioavailable HIV-1 non-nucleoside reverse transcriptase inhibitor with improved potency against key mutant viruses. J Med Chem 51: 6503-6511.
Derridj F, Djebbar S, Benali-Baitich O, Doucet H (2008) Direct arylation of oxazole and benzoxazole with aryl of heteroaryl halides using palladium-diphosphine catalyst. J Organomet Chem 693: 135-144.
Liu C, Zhang SH, Wang MJ, Liang QZ, Jian XG (2005) Synthesis and characterization of poly (ether amide)s containing bisphthalazinone and ether linkages. Chin Chem Lett 16: 437-439.
Mahajan SS, Mahalakshmi A (2006) Synthesis of 2-amino-5-chlorobenzonitrile. Indian J Chem 45B: 1299-1300.
Babu SG, Karvembu R (2011) CuO Nanoparticles: A simple, effective, ligand free, and reusable heterogeneous catalyst for N-arylation of benzimidazoles. Ind Eng Chem Res 50: 9594-9600.
Blessy M, Patel RD, Prajapati PN, Agrawal YK (2014) Development of forced degradation and stability indicating studies of drugs-A review. J Pharm Anal 4: 159-165.
Panyachariwat N, Steckel H (2014) Stability of urea in solution and pharmaceutical preparations. J Cosmet Sci 65: 187-195.
Rowe S (2007) The importance of a robust assessment procedure in protecting against rapid overpressure hazards. I Chem Eng Symp Ser No. 153.
Nolan PF, Barton JA (1987) Some lessons from thermal-runaway incidents. J Hazard Mater 14: 233-239.
Gustin JL, Fines A (1996) Safety of chlorination reactions. I Chem Eng Symp Ser No. 141.
Rivera-Ruiz M, Cajavilca C, Varon J (2008) Einthoven's string galvanometer: The first electrocardiograph. Tex Heart Inst J 35: 174-178.
Rubik B (2002) The biofield hypothesis: Its biophysical basis and role in medicine. J Altern Complement Med 8: 703-717.
Saad M, Medeiros RD (2012) Distant healing by the supposed vital energy- Scientific bases. Complementary Therapies for the Contemporary Healthcare. U.S.
Rae A (2006) Quantum Physics: A beginner’s guide. One world publications.
Thomas AH (2012) Hidden in plain sight: The simple link between relativity and quantum mechanics. Swansea, UK.
NIH, National Center for Complementary and Alternative Medicine. CAM Basics. Publication 347. [October 2, 2008]. Available at:
Trivedi MK, Patil S, Shettigar H, Gangwar M, Jana S (2015) An effect of biofield treatment on multidrug-resistant Burkholderia cepacia: A multihost pathogen. J Trop Dis 3: 167.
Trivedi MK, Patil S, Shettigar H, Gangwar M, Jana S (2015) Antimicrobial sensitivity pattern of Pseudomonas fluorescens after biofield treatment. J Infect Dis Ther 3: 222.
Trivedi MK, Patil S, Shettigar H, Bairwa K, Jana S (2015) Phenotypic and biotypic characterization of Klebsiella oxytoca: An impact of biofield treatment. J Microb Biochem Technol 7: 203-206.
Sances F, Flora E, Patil S, Spence A, Shinde V (2013) Impact of biofield treatment on ginseng and organic blueberry yield. Agrivita J Agric Sci 35: 22-29.
Lenssen AW (2013) Biofield and fungicide seed treatment influences on soybean productivity, seed quality and weed community. Agricultural Journal 8: 138-143.
Nayak G, Altekar N (2015) Effect of biofield treatment on plant growth and adaptation. J Environ Health Sci 1: 1-9.
Patil SA, Nayak GB, Barve SS, Tembe RP, Khan RR (2012) Impact of biofield treatment on growth and anatomical characteristics of Pogostemon cablin (Benth.). Biotechnology 11: 154-162.
Trivedi MK, Tallapragada RM, Branton A, Trivedi D, Nayak G, et al. (2015) Potential impact of bio field treatment on atomic and physical characteristics of magnesium. Vitam Miner 3: 129.
Trivedi MK, Patil S, Shettigar H, Singh R, Jana S (2015) An impact of biofield treatment on spectroscopic characterization of pharmaceutical compounds. Mod Chem appl 3: 159.
Trivedi MK, Patil S, Tallapragada RMR (2015) Effect of biofield treatment on the physical and thermal characteristics of aluminium powders. Ind Eng Manag 4: 151.
Trivedi MK, Nayak G, Patil S, Tallapragada RM, Latiyal O (2015) Studies of the atomic and crystalline characteristics of ceramic oxide nano powders after bio field treatment. Ind Eng Manage 4: 161.
Pavia DL, Lampman GM, Kriz GS (2001) Introduction to spectroscopy. (3rdedn), Thomson Learning, Singapore.
Britton D (2007) o-Chloro- and o-bromobenzo-nitrile: Pseudosymmetry and pseudo-isostructural packing. Acta Crystallogr C 63: o14-o16.
Trivedi MK, Patil S, Tallapragada RM (2013) Effect of biofield treatment on the physical and thermal characteristics of silicon, tin and lead powders. J Material Sci Eng 2: 125.
Krishnan AR, Saleem H, Subashchandrabose S, Sundaraganesan N, Sebastain S (2011) Molecular structure, vibrational spectroscopic (FT-IR, FT-Raman), UV and NBO analysis of 2-chlorobenzonitrile by density functional method. Spectrochim Acta A Mol Biomol Spectrosc 78: 582-589.
Sudha S, Sundaraganesan N, Kurt M, Cinar M, Karabacak M (2011) FT-IR and FT-Raman spectra, vibrational assignments, NBO analysis and DFT calculations of 2-amino-4-chlorobenzonitrile. J Mol Struct 985: 148-156.
Science Publishing Group
1 Rockefeller Plaza,
10th and 11th Floors,
New York, NY 10020
Tel: (001)347-983-5186