Rhizome Extract of White Ginger (Zingiber officinale Roxb) Maintains Testicular Function of Aging Mice
International Journal of Nutrition and Food Sciences
Volume 5, Issue 3, May 2016, Pages: 175-178
Received: Mar. 27, 2016; Accepted: Apr. 5, 2016; Published: Apr. 26, 2016
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Authors
Sutyarso , Department of Biology, Faculty of Mathematics and Natural Sciences University of Lampung, Bandar Lampung, Indonesia
Hendri Busman, Department of Biology, Faculty of Mathematics and Natural Sciences University of Lampung, Bandar Lampung, Indonesia
Mohammad Kanedi, Department of Biology, Faculty of Mathematics and Natural Sciences University of Lampung, Bandar Lampung, Indonesia
Muhartono , Department of Anatomical Pathology, Faculty of Medicine, University of Lampung, Bandar Lampung, Indonesia
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Abstract
Ginger is recognized as antioxidants and chemoprotective. Therefore the rhizome extract of this plant could allegedly reverse aging process. The study is intended to investigate the possible effects of rhizome extract of white ginger (Zingiber officinale Roxb.) on the testicular function of aging male mice (Mus musculus Linn.). Male albino mice aged 12-14 months, grouped into three consisted of 12 mice, were given extract orally as follows: 0 mg/kg (as a control), 50mg/kg and 100 mg/kg daily for 70 days. The testicular function parameters assessed were: the number of spermatogenic cells, the number and quality of sperm. Compared to control group, male mice treated with ginger extract showed significant high quality of sperm count, viability, motility and morphology (P<0.001). Histological parameters of the testis: pre-leptotene as well as pachytene spermatocytes and spermatids cells also significantly higher in the treated group (P <0.01) than that of control. In conclusion, rhizome extract of ginger effectively maintain function of reproductive system of male mice in aging process and, thus, ginger is potentially as the fertility and anti-aging herbs.
Keywords
Ginger, Testicular Function, Anti-aging, Antioxidants
To cite this article
Sutyarso , Hendri Busman, Mohammad Kanedi, Muhartono , Rhizome Extract of White Ginger (Zingiber officinale Roxb) Maintains Testicular Function of Aging Mice, International Journal of Nutrition and Food Sciences. Vol. 5, No. 3, 2016, pp. 175-178. doi: 10.11648/j.ijnfs.20160503.14
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Copyright © 2016 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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