Evaluation of Nutritional Status and Heavy Metals Toxicity for Asthmatic Children
International Journal of Nutrition and Food Sciences
Volume 5, Issue 3, May 2016, Pages: 224-233
Received: Apr. 27, 2016; Accepted: May 12, 2016; Published: May 27, 2016
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Authors
Ghada M. El-Kherbawy, Department of Food Science, Faculty of Agriculture, Cairo University, Giza, Egypt
Amany A. Salem, Special Food and Nutrition Department, Food Technology Research Institute, ARC, Giza, Egypt
Mona S. Mahklouf, Consltant Paediatrician, Pediatric Department, Al- Galaa El-Teaching Hospital, Cairo, Egypt
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Abstract
The present study aimed to investigate blood heavy metals toxicity for asthmatic children and their nutritional status. One hundred children suffering asthma attending the Al-Galaa Teaching Hospital during winter were enrolled in the study. Data was collected by personal interview with their mothers to fill a special questionnaire sheet (socioeconomic and clinical characteristics, anthropometric measurements and 24h dietary recall). Results showed most parents had (10–12 years) of education levels. The majority of fathers were smoking at the same room with their children. All children had high blood levels of lead (B-Pb) and cadmium (B-Cd). Most children were intake less than 50% of DRI from fiber, vitamins (A, D, B1 and B2) and minerals (K and Mg). There were a negative significant correlation between B-Pb and both Hb and animal protein (r = 0.312 and r = 278, P ˂0.05, respectively). There were a significant correlation between B-Cd and bilirubin (r = -0.381, P ˂0.05). Also, there were adverse significant correlation between plasma K and both urea and creatinine (P ˂0.01). It is concluded preventing heavy metals poisoning in early childhood is an essential component of strategy to improve the health success.
Keywords
Children, Nutritional Status, Heavy Metals, Asthma, Dietary Intake, Liver and Kidney Function
To cite this article
Ghada M. El-Kherbawy, Amany A. Salem, Mona S. Mahklouf, Evaluation of Nutritional Status and Heavy Metals Toxicity for Asthmatic Children, International Journal of Nutrition and Food Sciences. Vol. 5, No. 3, 2016, pp. 224-233. doi: 10.11648/j.ijnfs.20160503.21
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Copyright © 2016 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
References
[1]
Kempen, E; Fischer, P; Janssen, N; Houthuijs, D; Kampa, I; Stansfeld, S; Cassee, F (2012). Neurobehavioral effects of exposure to traffic-related air pollution and transportation noise in primary schoolchildren. Environ Res. 115: 8-25. DOI: 10.1016/j.envres.2012.03.002.
[2]
Olmo, NRS; Saldiva, PHN; Braga, ALF; Lin, CA; Santos, UP and Pereira, LAA (2011). A review of low-level air pollution and adverse effects on human health: implications for epidemiological studies and public policy. Clinics, 66 (4): 681-90. DOI: 10.1590/S1807-59322011000400025.
[3]
Gore A (1997). Respect the land, Our Precious Plant, Time Magazine, 150 (17A): 8-9.
[4]
Duruibe, JO; Ogwuegbu, MOC and Egwurugwu, JN (2007). Heavy metal pollution and human biotoxic effects. International Journal of Physical Sciences Vol. 2 (5), pp. 112-118.
[5]
El-Desoky, G; Aboul-Soud, M; Al-Othman, Z; Habila, M and Giesy, J (2014). Seasonal concentrations of lead in outdoor and indoor dust and blood of children in Riyadh, Saudi Arabia. Environmental Geochemistry and Health, 36, 583-593.
[6]
Nicolussi, FH; Milla dos Santos, AP; André, SC; Veiga, TB and Takayanagui, AMM (2014). Air pollution and respiratory allergic diseases in schoolchildren. Rev Saúde Pública; 48 (2): 1-5.
[7]
Salvi, S (2001). Pollution and allergic airways disease. Curr. Opin. Allergy. Clin. Immunol. 1: 35-41.
[8]
Miller, AL (2001). The Etiologies, Pathophysiology and Alternative/ Complementary Treatment of Asthma. Altern. Med. Rev. Feb; 6: 20-47.
[9]
Mathew, J; Goyal, R; Taneja, KK and Aror, N (2014). Air pollution and respiratory health of school children in industrial, commercial and residential areas of Delhi Air Quality. Atmosphere and Health, ISSN: 1873-9318.
[10]
Landrigan PJ; Carlson JE; Bearer CF; Cranmer JS; Bullard R; Etzel RA; Groopman J; McLachlan JA; Perera EP; Reigart JR; Robison L; Schell L and Suk WA (1998). Children’s health and the environment: a new agenda for prevention research. Environ Health Persp, 106 Suppl. 3: 787-94.
[11]
Da Costa, JL; Navarro, A; Neves, JB and Martin, M (2004). Household wood and charcoal smoke increases risk of otitis media in childhood in Maputo. Int. J. Epidemiol. 33 (3): 573-578.
[12]
Soutar, A; Seaton, A. and Brown, K (1997). Bronchial reactivity and dietary antioxidants. Thorax. 52: 166-70.
[13]
El-Nahal, DM (2010). Effect of using pectin on lead toxicity. The Journal of American Science, 6 (12): 541-554.
[14]
Fagerstedta, S; Kipplerb, M; Annika Scheyniusc, A; Gutzeitc, C; Miea, A; Alma, JD and Vahterb, M (2015). Anthroposophic lifestyle influences the concentration of metals in placenta and cord blood. Environmental Research Volume 136, 88-96.
[15]
Krajčovičová-Kudláčková, M; Ursínyová, M; Mašánová, V; Béderová, A and Valachovičová, M (2006). Cadmium blood concentrations in relation to nutrition. Cent. Eur. J. Publ. Health; 14 (3): 126-129.
[16]
Jelliffe, DP and Jelliffe, EFP (1989). Community nutrition assessment; with special references to less technically developed countries. Oxford: Oxford University press, 482-960.
[17]
World Health Organization (WHO) and United Nations Children’s Fund (UNICEF) (2009) WHO Child Growth Standards and the Identification of Severe Acute Malnutrition in Infants and Children. Department of Child and Adolescent Health and Development, World Health Organization Press, Geneva.
[18]
Blössner, M., Siyam, A., Borghi, E. and Onyango, A. (2010) WHO AnthroPlus Software. WHO, Department of Nutrition for Health and Development, Geneva. http://www.who.int/childgrowth/software/anthro_pc_manual.pdf
[19]
Food Composition Tables for Egypt (2006). National Nutrition Institute. Second edition, Cairo, Egypt.
[20]
National Academy of Science (1998). First two of the dietary Reference Intake series (DRI) copyright 1997 and 1998. Country of the National Academy press. Washington, D. C.
[21]
Food and Nutrition Board, Institute of Medicine (2000). Dietary reference intakes for Vitamin C, Vitamin E, Selenium and Carotenoids. Washington, DC: National Academy Press.
[22]
Food and Nutrition Board, Institute of Medicine (2001). Dietary reference intakes for vitamin A, vitamin K, arsenic, boron, chromium, copper, iodine, iron, manganese, molybdenum, nickel, silicon, vanadium, and zinc. Washington, DC: National Academy Press.
[23]
Food and Nutrition Board, Institute of Medicine (2002/2005). Dietary reference intakes for Energy, Carbohydrate, Fiber, Fatty acids, Cholesterol, Protein and Amino acids. Washington, DC: National Academy Press.
[24]
Food and Nutrition Board, Institute of Medicine (2011). Dietary reference intakes for Calcium and Vitamin D. Washington, DC: National Academy Press.
[25]
Moser, K; Seelenbinder, F; McFadden, S; Adkins, C; Goshay, M and Davis, F (2001). Selecting a new analyzer for the hematology laboratory: The experience at Ohio Health Hospital. In: Laboratory Hematology. 7: 245-254.
[26]
Reitman, S and Frankel, S (1957). A calorimetric method for the determination of glutamic oxalacetic and glutamic pyruvic transaminase. J. Clin. Path., 28: 56-63.
[27]
Belfield, A and Golobkrg, DM (1971): Human serum glucose-6- phosphate activity conformation of its presence and lack of diagnostic value. Enzyme 12: 561.
[28]
Bonsens, KE and Taussky, DH (1984). Determination of serum creatinine. J Chem. Inv., 27: 648-660.
[29]
Kanter, MW (1975). Clinical Chemistry. The Bobber Merrill Company Inc., USA, p. 80.
[30]
Jendrassik, A (1983). Determination of bilirubine in blood serum. Biochem., Z. V., 297-304.
[31]
Tripathi, RM; Raghunath, R; Mahapatra, S and Sadasivan S (2001). Blood lead and its effect on Cd, Cu, Zn, Fe and hemoglobin levels of children. The Science of the Total Environment 277, 161-168.
[32]
Moura, M and Valente, JG (2002). Blood lead levels during pregnancy in women living in Riode-Janerio, Brazil. The science of the total Environment, 299 (1-3): pp. 123-129.
[33]
Weatherburn, MW; Baker, PJ and Logan, JE (1982). Serum calcium methodology-a Canadian assessment based on the application of the reference method. Clin Biochem., 1522-1529.
[34]
Guder, W; Hoffmann G and Oppitz KH (1982). Normalbereiche klin. Chem. Befunde in den Krankenhäusern Münchens.
[35]
Tietz NW (1976). Fundamentals of Clinical Chemistry. WB Saunders Co, Philadelphia, P A; Sec. Edit., 876.
[36]
SPSS (2009). Statistical Algorithm, SPSS Inc., Reports Library of Congress, US.
[37]
World Health Organization (WHO) REGIONAL OFFICE FOR AFRICA (2015). Lead Exposure in African Children Contemporary Sources and Concerns. WHO Regional Office for Africa, P. O. Box 6, Brazzaville, Republic of Congo, Email: (afrobooks@afro.who.int). ISBN: 978-0-86970-787-6.
[38]
McConnell, R; Berhane, K; Yao, L; Jerrett, M; Lurmann, F; Gilliland, F; Künzli, N; Gauderman, J; Avol, E; Thomas, D and Peters, J (2006). Traffic, susceptibility and childhood asthma. Environ. Health. Perspect; 114 (5): 766-772.
[39]
Miller, JE (2000). The Effects of Race/Ethnicity and Income on Early Childhood Asthma Prevalence and Health Care Use. American Journal of Public Health. Vol. (90), No 3: 428-430.
[40]
Chen, E; Matthews, KA and Boyce, TW (2002). Socioeconomic Differences in Children’s Health: How and Why Do These Relationships Change With Age? Psychological Bulletin Copyright 2002 by the American Psychological Association, Inc., Vol. 128, No. 2, 295-329.
[41]
Solon, O; Riddell, TJ; Quimbc, SA; BUTRICK, E; AYLward, GP; Bacate, ML and Peabody, JW (2008). Associations between Cognitive Function, Blood Lead Concentration, and Nutrition among Children in the Central Philippines. J. Pediatrics, 152: 237-43.
[42]
Attia, WMK; Abdel-Kareem, FM; Mohamed AA and Hussein, AH (1996). Screening tools detection of children at risk for lead exposure. Zagazig Univ. Med. J., 11 (2): 144-153.
[43]
Després, C; Beuter, A; Richer, F; Poitras, K; Veilleux, A; Ayotte, P; Dewailly, E; Saint-Amour, D and Muckle, G (2005). Neuromotor functions in Inuit preschool children exposed to Pb, PCBs, and Hg. Neurotoxicology and Teratology 27; 245-257.
[44]
Sharaf, NE; Abdel-Shakour, A; Amer, NM; Abou-Donia, MA and Khatab, N (2008). Evaluation of Children's Blood Lead Level in Cairo, Egypt. American-Eurasian J. Agric. & Environ. Sci., 3 (3): 414-419.
[45]
Tietz NW (1995). General clinical tests. In: Tietz NW, editor. Clinical guide to laboratory tests. Philadelphia: WB Saunders Co.
[46]
Friedman, LS; Lukyanova, EM; Kundiev, YI; Shkiryak-Nizhnyk, ZA; Chislovska, NV; Mucha, A; Zvinchuk, AV; Oliynyk, I and Hryhorczuk, D (2006). Anthropometric, environmental and dietary predictors of elevated blood cadmium levels in Ukrainian children: Ukraine ELSPC group. Environmental Research 102, 83-89.
[47]
Galal-Gorchev, H (1993). Dietary intake in food and estimated intake of lead, Cadmium and mercury. Food Additives Contaminants 10 (1): 115-128.
[48]
Evens, A; Hryhorczuk, D; Lanphear, BP; Rankin, KM; Lewis, DA; Forst, L and Deborah Rosenberg, D (2015). The impact of low-level lead toxicity on school performance among children in the Chicago Public Schools: a population-based retrospective cohort study. Environmental Health; 14-21. DOI 10.1186/s12940-015-0008-9.
[49]
El-Kherbawy, GM (2010). Nutritional status of pre-school children in a private kindergarten. The 1st international conference on: better life for women and poor families (End of poverty), Home economics department, Faculty of Agriculture, Alexandria University, 219-235.
[50]
Abdelaziz, SB; Youssef, MRL; Sedrak1, AS and Labib, JR (2015). Nutritional Status and Dietary Habits of School Children in Beni-Suef Governorate, Egypt. Food and Nutrition Sciences, 6, 54-63.
[51]
Hassan, NE; Yamamah, GA; El-Masry, SA; Abd-El-Dayem, SM and Farid, T (2012). Nutritional Status among South Sinai Children using Anthropometric measures. Journal of Applied Sciences Research, 8 (8): 4574-4580.
[52]
Bárány, E; Bergdahl, IA; Bratteby, LE; Lundh, T; Samuelson, G; Skerfving, S and Oskarsson, A (2005). Iron status influences trace element levels in human blood and serum. Environ Res; 98 (2): 215-23.
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