The Anticancer Effects of Hexane Extract of Rainbow Trout (Oncorhynchus mykiss) Muscle Enriched with Vegetable Oil Brasica sp.

Poroshad Montazeri Shahtoori; Mozhgan Emtyazjoo; Shahin Bonakdar; Mohammad Rabani

doi:doi:10.11648/j.crj.20150304.11

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The Anticancer Effects of Hexane Extract of Rainbow Trout (Oncorhynchus mykiss) Muscle Enriched with Vegetable Oil Brasica sp.

Poroshad Montazeri Shahtoori, Mozhgan Emtyazjoo, Shahin Bonakdar, Mohammad Rabani

Published in Cancer Research Journal (Volume 3, Issue 4)

Received: 25 May 2015 Accepted: 16 June 2015 Published: 3 July 2015

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Abstract

Background: As Canola oil (Brasica sp.) has beneficial compositions of essential fatty acids like saturated fatty acids, mono unsaturated fatty acids (MUFA) and poly unsaturated fatty acids (PUFA), practically it use in many experimental purposes. There are considerable amounts of oleic acid which is mono unsaturated fatty acids in canola oil that caused a good resistance to thermal processes such as deep frying. Rainbow trout is the main fish species farmed in about 85% of the total rate allocated to producing aquaculture fish in Iran. Rainbow trout has found in food baskets of many people due to its high nutritional value. Methods: in this study the hexane extracts of fish muscle isolated with purity of 250, 50, 10, 5 and 0.5 μg/ml at regular intervals of 24, 48 and 72 hours to determine the effects of hexane extracts on parameters which are associated with the survival of skin cancer cells A431 by MTT method in vitro comparison. Results: The effect of various concentrations of hexane extracts from fish muscle showed that the extracts of muscle at varying time intervals in hexane extracts administration had different effects on mortality of A431 cancer cells. Increasing of hexane extracts had significantly decreased the carcinogenic cells. The concentrations of hexane extract in 250 μg/ml at 24 hours were killed 50 percent of skin cancer A431cell lines. The addition of Brasica sp. vegetable oil as a dietary supplement is required to fish diet rations. Conclusion: In the present study the hexane extract inhibit the growth of cancer cells where the extract can be used as an anticancer agent for the operation of this lineage.

Published in	Cancer Research Journal (Volume 3, Issue 4)
DOI	10.11648/j.crj.20150304.11
Page(s)	63-67
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Cancer, Rainbow Trout (Oncorhynchus mykiss), Canola Oil (Brasica sp.), MTT Assay

References

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[2]	Beigmohammadi, Z , Maghsoudlou, Y., Sadeghi Mahoonak, A.R. & Safafar, H., 2009. Fatty acids Profile, Physicochemical Properties and Mineral Contents of Oil of Major Canola Varieties Grown in (Golestan Province). J. Agric. Sci. Natur. Resour., Vol. 16(2).
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[5]	Chiddambara, K.N., Vanitha, A., Rajesha, j., Mahadeva Swamy, M., Sowmya, P.R., Gokare, A. Ravishankar, 2004. Invivo antioxidant activity of carotenoids from Dunaliella salina – agreen microalga, Life Science., Vol. 76, PP:1381-1390.
[6]	Emtyazjoo, Mo., Moghadasi, Z., Rabbani, M., Emtyazjoo, Ma., Samadi, S. & Mossaffa, N., 2012. Anticancer effect of Dunaliella salina under stress and normal conditions against skin carcinoma cell line A431 in vitro. Iranian Journal of Fisheries Sciences, 11(2); pp: 283-293.
[7]	Jafari, S.M.A., Rabbani, M., Emtyazjoo, M. & Piryaei, F., 2014. Effect of dietary Spirulina platensis on fatty acid composition of rainbow trout (Oncorhynchus mykiss) fillet. Aquacult Int, DOI 10.1007/s10499-013-9748-0.
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[12]	Sadegi-aliabadi, H., Asghari, G., Mostafavi, S.A., Esmaeili, A.,2009. Solvent optimization on Taxol extraction from Taxus baccata L., using HPLC and LC-MS Daru; 17(3): 192-198.
[13]	Schwartz, J. ; Shklar, G. 1988. Prevention of experimental oral cancer by extracts of spirulina-dunaliella algae. Harvard School of Dental Medicine. Pub. In Nutrition and Cancer 11, 127-134. 1988. USA.
[14]	Siavash, B., Carapetian, J. & Zare, S., 2005. Studying on lipid content and fatty acids in some varieties of colza (Brassica napus L.). Pajouhesh & Sazandegi, No:67; pp: 95-101. (In Persian).
[15]	Stryker, W.S., Stampfer, M.J., Stein, E.A., Kaplan, L., Louis, T.A., Sober, A., Wlllett, W.C., 1990. Diet, plasma levels of beta-carotene and alpha-tocopherol, and risk of malignant melanoma., Channing Laboratory, Boston, MA 02115, Am J Epidemiol; 131:597-611.- Tim et al., 2007
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Poroshad Montazeri Shahtoori, Mozhgan Emtyazjoo, Shahin Bonakdar, Mohammad Rabani. (2015). The Anticancer Effects of Hexane Extract of Rainbow Trout (Oncorhynchus mykiss) Muscle Enriched with Vegetable Oil Brasica sp.. Cancer Research Journal, 3(4), 63-67. https://doi.org/10.11648/j.crj.20150304.11

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ACS Style

Poroshad Montazeri Shahtoori; Mozhgan Emtyazjoo; Shahin Bonakdar; Mohammad Rabani. The Anticancer Effects of Hexane Extract of Rainbow Trout (Oncorhynchus mykiss) Muscle Enriched with Vegetable Oil Brasica sp.. Cancer Res. J. 2015, 3(4), 63-67. doi: 10.11648/j.crj.20150304.11

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AMA Style

Poroshad Montazeri Shahtoori, Mozhgan Emtyazjoo, Shahin Bonakdar, Mohammad Rabani. The Anticancer Effects of Hexane Extract of Rainbow Trout (Oncorhynchus mykiss) Muscle Enriched with Vegetable Oil Brasica sp.. Cancer Res J. 2015;3(4):63-67. doi: 10.11648/j.crj.20150304.11

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@article{10.11648/j.crj.20150304.11,
  author = {Poroshad Montazeri Shahtoori and Mozhgan Emtyazjoo and Shahin Bonakdar and Mohammad Rabani},
  title = {The Anticancer Effects of Hexane Extract of Rainbow Trout (Oncorhynchus mykiss) Muscle Enriched with Vegetable Oil Brasica sp.},
  journal = {Cancer Research Journal},
  volume = {3},
  number = {4},
  pages = {63-67},
  doi = {10.11648/j.crj.20150304.11},
  url = {https://doi.org/10.11648/j.crj.20150304.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.crj.20150304.11},
  abstract = {Background: As Canola oil (Brasica sp.) has beneficial compositions of essential fatty acids like saturated fatty acids, mono unsaturated fatty acids (MUFA) and poly unsaturated fatty acids (PUFA), practically it use in many experimental purposes. There are considerable amounts of oleic acid which is mono unsaturated fatty acids in canola oil that caused a good resistance to thermal processes such as deep frying. Rainbow trout is the main fish species farmed in about 85% of the total rate allocated to producing aquaculture fish in Iran. Rainbow trout has found in food baskets of many people due to its high nutritional value. Methods: in this study the hexane extracts of fish muscle isolated with purity of 250, 50, 10, 5 and 0.5 μg/ml at regular intervals of 24, 48 and 72 hours to determine the effects of hexane extracts on parameters which are associated with the survival of skin cancer cells A431 by MTT method in vitro comparison. Results: The effect of various concentrations of hexane extracts from fish muscle showed that the extracts of muscle at varying time intervals in hexane extracts administration had different effects on mortality of A431 cancer cells. Increasing of hexane extracts had significantly decreased the carcinogenic cells. The concentrations of hexane extract in 250 μg/ml at 24 hours were killed 50 percent of skin cancer A431cell lines. The addition of Brasica sp. vegetable oil as a dietary supplement is required to fish diet rations. Conclusion: In the present study the hexane extract inhibit the growth of cancer cells where the extract can be used as an anticancer agent for the operation of this lineage.},
 year = {2015}
}

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TY - JOUR
T1 - The Anticancer Effects of Hexane Extract of Rainbow Trout (Oncorhynchus mykiss) Muscle Enriched with Vegetable Oil Brasica sp.
AU - Poroshad Montazeri Shahtoori
AU - Mozhgan Emtyazjoo
AU - Shahin Bonakdar
AU - Mohammad Rabani
Y1 - 2015/07/03
PY - 2015
N1 - https://doi.org/10.11648/j.crj.20150304.11
DO - 10.11648/j.crj.20150304.11
T2 - Cancer Research Journal
JF - Cancer Research Journal
JO - Cancer Research Journal
SP - 63
EP - 67
PB - Science Publishing Group
SN - 2330-8214
UR - https://doi.org/10.11648/j.crj.20150304.11
AB - Background: As Canola oil (Brasica sp.) has beneficial compositions of essential fatty acids like saturated fatty acids, mono unsaturated fatty acids (MUFA) and poly unsaturated fatty acids (PUFA), practically it use in many experimental purposes. There are considerable amounts of oleic acid which is mono unsaturated fatty acids in canola oil that caused a good resistance to thermal processes such as deep frying. Rainbow trout is the main fish species farmed in about 85% of the total rate allocated to producing aquaculture fish in Iran. Rainbow trout has found in food baskets of many people due to its high nutritional value. Methods: in this study the hexane extracts of fish muscle isolated with purity of 250, 50, 10, 5 and 0.5 μg/ml at regular intervals of 24, 48 and 72 hours to determine the effects of hexane extracts on parameters which are associated with the survival of skin cancer cells A431 by MTT method in vitro comparison. Results: The effect of various concentrations of hexane extracts from fish muscle showed that the extracts of muscle at varying time intervals in hexane extracts administration had different effects on mortality of A431 cancer cells. Increasing of hexane extracts had significantly decreased the carcinogenic cells. The concentrations of hexane extract in 250 μg/ml at 24 hours were killed 50 percent of skin cancer A431cell lines. The addition of Brasica sp. vegetable oil as a dietary supplement is required to fish diet rations. Conclusion: In the present study the hexane extract inhibit the growth of cancer cells where the extract can be used as an anticancer agent for the operation of this lineage.
VL - 3
IS - 4
ER -

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Author Information

Poroshad Montazeri Shahtoori

Faculty of marine science and technology, Islamic Azad University North Tehran Branch, Tehran, Iran
Mozhgan Emtyazjoo

Faculty of marine science and technology, Islamic Azad University North Tehran Branch, Tehran, Iran
Shahin Bonakdar

National cell Bank Department, Faculty of Pasteur Institute of Iran, Tehran, Iran
Mohammad Rabani

Faculty of marine science and technology, Islamic Azad University North Tehran Branch, Tehran, Iran

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Poroshad Montazeri Shahtoori, Mozhgan Emtyazjoo, Shahin Bonakdar, Mohammad Rabani. (2015). The Anticancer Effects of Hexane Extract of Rainbow Trout (Oncorhynchus mykiss) Muscle Enriched with Vegetable Oil Brasica sp.. Cancer Research Journal, 3(4), 63-67. https://doi.org/10.11648/j.crj.20150304.11

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ACS Style

Poroshad Montazeri Shahtoori; Mozhgan Emtyazjoo; Shahin Bonakdar; Mohammad Rabani. The Anticancer Effects of Hexane Extract of Rainbow Trout (Oncorhynchus mykiss) Muscle Enriched with Vegetable Oil Brasica sp.. Cancer Res. J. 2015, 3(4), 63-67. doi: 10.11648/j.crj.20150304.11

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AMA Style

Poroshad Montazeri Shahtoori, Mozhgan Emtyazjoo, Shahin Bonakdar, Mohammad Rabani. The Anticancer Effects of Hexane Extract of Rainbow Trout (Oncorhynchus mykiss) Muscle Enriched with Vegetable Oil Brasica sp.. Cancer Res J. 2015;3(4):63-67. doi: 10.11648/j.crj.20150304.11

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@article{10.11648/j.crj.20150304.11,
  author = {Poroshad Montazeri Shahtoori and Mozhgan Emtyazjoo and Shahin Bonakdar and Mohammad Rabani},
  title = {The Anticancer Effects of Hexane Extract of Rainbow Trout (Oncorhynchus mykiss) Muscle Enriched with Vegetable Oil Brasica sp.},
  journal = {Cancer Research Journal},
  volume = {3},
  number = {4},
  pages = {63-67},
  doi = {10.11648/j.crj.20150304.11},
  url = {https://doi.org/10.11648/j.crj.20150304.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.crj.20150304.11},
  abstract = {Background: As Canola oil (Brasica sp.) has beneficial compositions of essential fatty acids like saturated fatty acids, mono unsaturated fatty acids (MUFA) and poly unsaturated fatty acids (PUFA), practically it use in many experimental purposes. There are considerable amounts of oleic acid which is mono unsaturated fatty acids in canola oil that caused a good resistance to thermal processes such as deep frying. Rainbow trout is the main fish species farmed in about 85% of the total rate allocated to producing aquaculture fish in Iran. Rainbow trout has found in food baskets of many people due to its high nutritional value. Methods: in this study the hexane extracts of fish muscle isolated with purity of 250, 50, 10, 5 and 0.5 μg/ml at regular intervals of 24, 48 and 72 hours to determine the effects of hexane extracts on parameters which are associated with the survival of skin cancer cells A431 by MTT method in vitro comparison. Results: The effect of various concentrations of hexane extracts from fish muscle showed that the extracts of muscle at varying time intervals in hexane extracts administration had different effects on mortality of A431 cancer cells. Increasing of hexane extracts had significantly decreased the carcinogenic cells. The concentrations of hexane extract in 250 μg/ml at 24 hours were killed 50 percent of skin cancer A431cell lines. The addition of Brasica sp. vegetable oil as a dietary supplement is required to fish diet rations. Conclusion: In the present study the hexane extract inhibit the growth of cancer cells where the extract can be used as an anticancer agent for the operation of this lineage.},
 year = {2015}
}

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