Science Journal of Clinical Medicine

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Retrospective Assessment of Irrational use of Antibiotics to Children Attending in Mekelle General Hospital

Received: 14 May 2014    Accepted: 06 June 2014    Published: 20 June 2014
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Abstract

Background: In the last decades, there has been an escalating consumption of antibiotics with the number of antibiotic prescriptions increasing worldwide. Since children are more vulnerable to infectious disease than adults, more antibiotics are prescribed for them. Inappropriate use of antibiotics has resulted in a major increase in the development of multi-drug resistant pathogens with great implication in terms of morbidity, mortality and costs. The objective of this study was to determine the irrational use of antibiotics prescribed for children under the age of 15 years in Mekelle general hospital. Methods: A retrospective cross sectional study was conducted. Four hundred three children’s prescriptions and corresponding cards which were recorded by the year 2012 were selected by systematic random sampling proportionally from each month in the year. Results: Of all antibiotic prescriptions reviewed, the numbers of outpatient antibiotic prescriptions were 222 (55.1%) while inpatient prescriptions were 181 (44.9%).The predefined antibiotics indicators like percentage of antibiotics prescribed, frequency of route of administration, antibiotics prescribed from Standard treatment guideline, proportion of antibiotics, cost of antibiotics per antibiotics days, incidence and antibiotics utilization ratio were determined and 141(35.1%) were treated with different antibiotics irrationally. Conclusion: The finding of this study indicated that antibiotics were prescribed irrationally. Prescriptions containing one or more antibiotics constituted 73.68% of all prescriptions and around 5.9% of encounters were treated without any diagnosis. T he study has revealed that third generation cephalosporin (ceftriaxone) has been highly prescribed in the study hospital.

DOI 10.11648/j.sjcm.20140303.14
Published in Science Journal of Clinical Medicine (Volume 3, Issue 3, May 2014)
Page(s) 46-51
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This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Antibiotics, Children, Cross sectional, Irrational, Mekelle, Retrospective

References
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[13] Menassie K: Cross-sectional survey of Drug use in Health facilities of Harari Region. MSc thesis. Addis Ababa University, pharmacology department; 2004.
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Author Information
  • Department of Medicine, Addis Ababa Science and Technology University, Addis Ababa, Ethiopia

  • College of Medicine and Health Science, Arba Minch University, Arba Minch, Ethiopia

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    Girum Sebsibie, Teklemariam Gultie. (2014). Retrospective Assessment of Irrational use of Antibiotics to Children Attending in Mekelle General Hospital. Science Journal of Clinical Medicine, 3(3), 46-51. https://doi.org/10.11648/j.sjcm.20140303.14

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    Girum Sebsibie; Teklemariam Gultie. Retrospective Assessment of Irrational use of Antibiotics to Children Attending in Mekelle General Hospital. Sci. J. Clin. Med. 2014, 3(3), 46-51. doi: 10.11648/j.sjcm.20140303.14

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    AMA Style

    Girum Sebsibie, Teklemariam Gultie. Retrospective Assessment of Irrational use of Antibiotics to Children Attending in Mekelle General Hospital. Sci J Clin Med. 2014;3(3):46-51. doi: 10.11648/j.sjcm.20140303.14

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  • @article{10.11648/j.sjcm.20140303.14,
      author = {Girum Sebsibie and Teklemariam Gultie},
      title = {Retrospective Assessment of Irrational use of Antibiotics to Children Attending in Mekelle General Hospital},
      journal = {Science Journal of Clinical Medicine},
      volume = {3},
      number = {3},
      pages = {46-51},
      doi = {10.11648/j.sjcm.20140303.14},
      url = {https://doi.org/10.11648/j.sjcm.20140303.14},
      eprint = {https://download.sciencepg.com/pdf/10.11648.j.sjcm.20140303.14},
      abstract = {Background: In the last decades, there has been an escalating consumption of antibiotics with the number of antibiotic prescriptions increasing worldwide. Since children are more vulnerable to infectious disease than adults, more antibiotics are prescribed for them. Inappropriate use of antibiotics has resulted in a major increase in the development of multi-drug resistant pathogens with great implication in terms of morbidity, mortality and costs. The objective of this study was to determine the irrational use of antibiotics prescribed for children under the age of 15 years in Mekelle general hospital. Methods: A retrospective cross sectional study was conducted. Four hundred three children’s prescriptions and corresponding cards which were recorded by the year 2012 were selected by systematic random sampling proportionally from each month in the year. Results: Of all antibiotic prescriptions reviewed, the numbers of outpatient antibiotic prescriptions were 222 (55.1%) while inpatient prescriptions were 181 (44.9%).The predefined antibiotics indicators like percentage of antibiotics prescribed, frequency of route of administration, antibiotics prescribed from Standard treatment guideline, proportion of antibiotics, cost of antibiotics per antibiotics days, incidence and antibiotics utilization ratio were determined and 141(35.1%) were treated with different antibiotics irrationally. Conclusion: The finding of this study indicated that antibiotics were prescribed irrationally. Prescriptions containing one or more antibiotics constituted 73.68% of all prescriptions and around 5.9% of encounters were treated without any diagnosis. T he study has revealed that third generation cephalosporin (ceftriaxone) has been highly prescribed in the study hospital.},
     year = {2014}
    }
    

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    T1  - Retrospective Assessment of Irrational use of Antibiotics to Children Attending in Mekelle General Hospital
    AU  - Girum Sebsibie
    AU  - Teklemariam Gultie
    Y1  - 2014/06/20
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    DO  - 10.11648/j.sjcm.20140303.14
    T2  - Science Journal of Clinical Medicine
    JF  - Science Journal of Clinical Medicine
    JO  - Science Journal of Clinical Medicine
    SP  - 46
    EP  - 51
    PB  - Science Publishing Group
    SN  - 2327-2732
    UR  - https://doi.org/10.11648/j.sjcm.20140303.14
    AB  - Background: In the last decades, there has been an escalating consumption of antibiotics with the number of antibiotic prescriptions increasing worldwide. Since children are more vulnerable to infectious disease than adults, more antibiotics are prescribed for them. Inappropriate use of antibiotics has resulted in a major increase in the development of multi-drug resistant pathogens with great implication in terms of morbidity, mortality and costs. The objective of this study was to determine the irrational use of antibiotics prescribed for children under the age of 15 years in Mekelle general hospital. Methods: A retrospective cross sectional study was conducted. Four hundred three children’s prescriptions and corresponding cards which were recorded by the year 2012 were selected by systematic random sampling proportionally from each month in the year. Results: Of all antibiotic prescriptions reviewed, the numbers of outpatient antibiotic prescriptions were 222 (55.1%) while inpatient prescriptions were 181 (44.9%).The predefined antibiotics indicators like percentage of antibiotics prescribed, frequency of route of administration, antibiotics prescribed from Standard treatment guideline, proportion of antibiotics, cost of antibiotics per antibiotics days, incidence and antibiotics utilization ratio were determined and 141(35.1%) were treated with different antibiotics irrationally. Conclusion: The finding of this study indicated that antibiotics were prescribed irrationally. Prescriptions containing one or more antibiotics constituted 73.68% of all prescriptions and around 5.9% of encounters were treated without any diagnosis. T he study has revealed that third generation cephalosporin (ceftriaxone) has been highly prescribed in the study hospital.
    VL  - 3
    IS  - 3
    ER  - 

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