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Aggregation Behaviour of Sodium Cholate and Sodium Deoxycholate Under the Influence of Drug (Disprine) in Aqueous Solution at Various Temperatures

Received: 22 September 2016    Accepted: 21 October 2016    Published: 25 November 2016
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Abstract

To get accurate concentration of drug in systemic way for pharmacological response, Solubility is an important parameter to be shown. Most of the newly discovered chemical entities of the drugs are subjected to lipid lover (lipophile) due to this it carries the properties of poor water solubility. That’s why solubility behavior is one of the most important for formational developments [24, 25]. Colloidal drug has to be in desired properties for the development of drug carrier, it is essential to examine physico-chemical properties of the systems. Bile salt mixed micelles are globally known as novel for drug delivery systems in living organism. The main purpose of the present method is to develop and examine the characterize mixed micelles [3] of anionic bile salts (Sodium deoxycholate and sodium cholate) and drug (Disprine or generic name Aspirin) in various temperatures.

DOI 10.11648/j.sr.20160405.12
Published in Science Research (Volume 4, Issue 5, October 2016)
Page(s) 112-119
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Bile Salts- Sodium Cholate, Sodium deoxycholate, Conductometer, Disprine, cmc, Counter Ion Dissociation, Micelle

References
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Author Information
  • Department of Applied Chemistry, Bhilai Institute of Technology, Durg, (C.G.) India

  • Department of Applied Chemistry, Bhilai Institute of Technology, Durg, (C.G.) India

  • Department of Biotechnology, National Institute of Technology, Durgapur, (W.B.) India

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  • APA Style

    Shweta Singh, Santosh K. Sar, Tonmoy Ray. (2016). Aggregation Behaviour of Sodium Cholate and Sodium Deoxycholate Under the Influence of Drug (Disprine) in Aqueous Solution at Various Temperatures. Science Research, 4(5), 112-119. https://doi.org/10.11648/j.sr.20160405.12

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    ACS Style

    Shweta Singh; Santosh K. Sar; Tonmoy Ray. Aggregation Behaviour of Sodium Cholate and Sodium Deoxycholate Under the Influence of Drug (Disprine) in Aqueous Solution at Various Temperatures. Sci. Res. 2016, 4(5), 112-119. doi: 10.11648/j.sr.20160405.12

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    AMA Style

    Shweta Singh, Santosh K. Sar, Tonmoy Ray. Aggregation Behaviour of Sodium Cholate and Sodium Deoxycholate Under the Influence of Drug (Disprine) in Aqueous Solution at Various Temperatures. Sci Res. 2016;4(5):112-119. doi: 10.11648/j.sr.20160405.12

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  • @article{10.11648/j.sr.20160405.12,
      author = {Shweta Singh and Santosh K. Sar and Tonmoy Ray},
      title = {Aggregation Behaviour of Sodium Cholate and Sodium Deoxycholate Under the Influence of Drug (Disprine) in Aqueous Solution at Various Temperatures},
      journal = {Science Research},
      volume = {4},
      number = {5},
      pages = {112-119},
      doi = {10.11648/j.sr.20160405.12},
      url = {https://doi.org/10.11648/j.sr.20160405.12},
      eprint = {https://download.sciencepg.com/pdf/10.11648.j.sr.20160405.12},
      abstract = {To get accurate concentration of drug in systemic way for pharmacological response, Solubility is an important parameter to be shown. Most of the newly discovered chemical entities of the drugs are subjected to lipid lover (lipophile) due to this it carries the properties of poor water solubility. That’s why solubility behavior is one of the most important for formational developments [24, 25]. Colloidal drug has to be in desired properties for the development of drug carrier, it is essential to examine physico-chemical properties of the systems. Bile salt mixed micelles are globally known as novel for drug delivery systems in living organism. The main purpose of the present method is to develop and examine the characterize mixed micelles [3] of anionic bile salts (Sodium deoxycholate and sodium cholate) and drug (Disprine or generic name Aspirin) in various temperatures.},
     year = {2016}
    }
    

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    AU  - Shweta Singh
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    AB  - To get accurate concentration of drug in systemic way for pharmacological response, Solubility is an important parameter to be shown. Most of the newly discovered chemical entities of the drugs are subjected to lipid lover (lipophile) due to this it carries the properties of poor water solubility. That’s why solubility behavior is one of the most important for formational developments [24, 25]. Colloidal drug has to be in desired properties for the development of drug carrier, it is essential to examine physico-chemical properties of the systems. Bile salt mixed micelles are globally known as novel for drug delivery systems in living organism. The main purpose of the present method is to develop and examine the characterize mixed micelles [3] of anionic bile salts (Sodium deoxycholate and sodium cholate) and drug (Disprine or generic name Aspirin) in various temperatures.
    VL  - 4
    IS  - 5
    ER  - 

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