Gold Nanoparticle Conjugated Organic Dye Nanocomposite Based Photostimulated Luminescent Enhancement and Its Application in Nanomedicine
American Journal of Nano Research and Applications
Volume 5, Issue 3-1, May 2017, Pages: 42-47
Received: Feb. 3, 2017; Accepted: Feb. 4, 2017; Published: Feb. 28, 2017
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Authors
Ketevan Chubinidze, Department of Biology, I. Javakhishvili Tbilisi State University, Georgia
Besarion Partsvania, Department of Biocybernetics, Institute of Cybernetics, Tbilisi, Georgia
Lali Devadze, Department of Optical-Chemical Research, Institute of Cybernetics, Tbilisi, Georgia
Tsisana Zurabishvili, Department of Optical-Chemical Research, Institute of Cybernetics, Tbilisi, Georgia
Nino Sepashvili, Department of Optical-Chemical Research, Institute of Cybernetics, Tbilisi, Georgia
Gia Petriashvili, Department of Optically Anisotropic Systems, Institute of Cybernetics, Tbilisi, Georgia
Mariam Chubinidze, Faculty of Medicine, Tbilisi State Medical University, Tbilisi, Georgia
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Abstract
We have experimentally demonstrated that the emission of visible light from the polymer matrix doped with luminescent dye and gold nanoparticles (GNPs) can be enhanced with the use of surface plasmon coupling. GNPs can enhance the luminescence intensity of nearby luminescent dye because of the interactions between the dipole moments of the dye and the surface plasmon field of the GNPs. The electric charge on the GNPs and the distance between GNPs and luminescent dye molecules have a significant effect on the luminescence intensity, and this enhancement depends strongly upon the excitation wavelength of the pumping laser source. This ability of controlling luminescence can be beneficially used in developing contrast agents for highly sensitive and specific optical sensing and imaging. It opens new possibilities for plasmonic applications in nanobiology and nanomedicine. In particular, for example, luminescent dye-conjugated GNPs and gold nanorods (GNRs), can be used to target specific cancer cells, which is very important for the diagnosis and therapy of cancer.
Keywords
Luminescent Organic Dyes, Nanocomposite, Polymers, Gold Nanoparticles, Gold Nanorods, Near Infrared Spectrum, Nanomedicine
To cite this article
Ketevan Chubinidze, Besarion Partsvania, Lali Devadze, Tsisana Zurabishvili, Nino Sepashvili, Gia Petriashvili, Mariam Chubinidze, Gold Nanoparticle Conjugated Organic Dye Nanocomposite Based Photostimulated Luminescent Enhancement and Its Application in Nanomedicine, American Journal of Nano Research and Applications. Special Issue: Nanotechnologies. Vol. 5, No. 3-1, 2017, pp. 42-47. doi: 10.11648/j.nano.s.2017050301.20
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