The Coordination Chemistry in the Antifungal Effect of Tin(IV)-Bis(Pyrimidin-2-Ylthio)Alkane Derivatives

Fernanda Andrade Mendonça; Geraldo José da Silva Junior; José Roberto da Silveira Maia; Onkar Dev Dhingra; Rosimeire Coura Barcelos

doi:doi:10.11648/j.ajac.20150302.17

The Coordination Chemistry in the Antifungal Effect of Tin(IV)-Bis(Pyrimidin-2-Ylthio)Alkane Derivatives

Fernanda Andrade Mendonça, Geraldo José da Silva Junior, José Roberto da Silveira Maia, Onkar Dev Dhingra, Rosimeire Coura Barcelos

Published in American Journal of Applied Chemistry (Volume 3, Issue 2)

Received: 20 March 2015 Accepted: 31 March 2015 Published: 9 April 2015

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Abstract

High productivity of agriculture goods is closely associated with the use of fungicides to reduce losses caused by the fungal plant diseases. However, appearance of resistant population of pathogens to several commercial fungicides is a common phenomenon that requires control. There is, therefore, need for developing novel fungicide compounds that are environmentally safe with low toxicity to wild life and humans. In this study novel organotin(IV) derivatives of bis(pyrimidin-2-ylthio)methane (ptm), bis(pyrimidin-2-ylthio)ethane (pte) and bis(pyrimidin-2-ylthio)hexane (pth) were tested against phytopathogens to evaluate their activity as potential fungicides. The bis(pyrimidin-2-ylthio)alkanes were not active in contrast with the organotin(IV) derivatives. The 5-coordinate triphenyltin(IV) derivatives were the most active compounds in a wide range of concentration. This study shows that the microorganisms were susceptible to the acid character of the organotin(IV) precursors.

Published in	American Journal of Applied Chemistry (Volume 3, Issue 2)
DOI	10.11648/j.ajac.20150302.17
Page(s)	77-82
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Antifungal, Organotin, Bis(Pyrimidin-2-Ylthio)Alkanes, Storage Fungus, Fungicide, Phytopathogens

References

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APA Style

Fernanda Andrade Mendonça, Geraldo José da Silva Junior, José Roberto da Silveira Maia, Onkar Dev Dhingra, Rosimeire Coura Barcelos. (2015). The Coordination Chemistry in the Antifungal Effect of Tin(IV)-Bis(Pyrimidin-2-Ylthio)Alkane Derivatives. American Journal of Applied Chemistry, 3(2), 77-82. https://doi.org/10.11648/j.ajac.20150302.17

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ACS Style

Fernanda Andrade Mendonça; Geraldo José da Silva Junior; José Roberto da Silveira Maia; Onkar Dev Dhingra; Rosimeire Coura Barcelos. The Coordination Chemistry in the Antifungal Effect of Tin(IV)-Bis(Pyrimidin-2-Ylthio)Alkane Derivatives. Am. J. Appl. Chem. 2015, 3(2), 77-82. doi: 10.11648/j.ajac.20150302.17

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AMA Style

Fernanda Andrade Mendonça, Geraldo José da Silva Junior, José Roberto da Silveira Maia, Onkar Dev Dhingra, Rosimeire Coura Barcelos. The Coordination Chemistry in the Antifungal Effect of Tin(IV)-Bis(Pyrimidin-2-Ylthio)Alkane Derivatives. Am J Appl Chem. 2015;3(2):77-82. doi: 10.11648/j.ajac.20150302.17

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@article{10.11648/j.ajac.20150302.17,
  author = {Fernanda Andrade Mendonça and Geraldo José da Silva Junior and José Roberto da Silveira Maia and Onkar Dev Dhingra and Rosimeire Coura Barcelos},
  title = {The Coordination Chemistry in the Antifungal Effect of Tin(IV)-Bis(Pyrimidin-2-Ylthio)Alkane Derivatives},
  journal = {American Journal of Applied Chemistry},
  volume = {3},
  number = {2},
  pages = {77-82},
  doi = {10.11648/j.ajac.20150302.17},
  url = {https://doi.org/10.11648/j.ajac.20150302.17},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajac.20150302.17},
  abstract = {High productivity of agriculture goods is closely associated with the use of fungicides to reduce losses caused by the fungal plant diseases. However, appearance of resistant population of pathogens to several commercial fungicides is a common phenomenon that requires control. There is, therefore, need for developing novel fungicide compounds that are environmentally safe with low toxicity to wild life and humans. In this study novel organotin(IV) derivatives of bis(pyrimidin-2-ylthio)methane (ptm), bis(pyrimidin-2-ylthio)ethane (pte) and bis(pyrimidin-2-ylthio)hexane (pth) were tested against phytopathogens to evaluate their activity as potential fungicides. The bis(pyrimidin-2-ylthio)alkanes were not active in contrast with the organotin(IV) derivatives. The 5-coordinate triphenyltin(IV) derivatives were the most active compounds in a wide range of concentration. This study shows that the microorganisms were susceptible to the acid character of the organotin(IV) precursors.},
 year = {2015}
}

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TY  - JOUR
T1  - The Coordination Chemistry in the Antifungal Effect of Tin(IV)-Bis(Pyrimidin-2-Ylthio)Alkane Derivatives
AU  - Fernanda Andrade Mendonça
AU  - Geraldo José da Silva Junior
AU  - José Roberto da Silveira Maia
AU  - Onkar Dev Dhingra
AU  - Rosimeire Coura Barcelos
Y1  - 2015/04/09
PY  - 2015
N1  - https://doi.org/10.11648/j.ajac.20150302.17
DO  - 10.11648/j.ajac.20150302.17
T2  - American Journal of Applied Chemistry
JF  - American Journal of Applied Chemistry
JO  - American Journal of Applied Chemistry
SP  - 77
EP  - 82
PB  - Science Publishing Group
SN  - 2330-8745
UR  - https://doi.org/10.11648/j.ajac.20150302.17
AB  - High productivity of agriculture goods is closely associated with the use of fungicides to reduce losses caused by the fungal plant diseases. However, appearance of resistant population of pathogens to several commercial fungicides is a common phenomenon that requires control. There is, therefore, need for developing novel fungicide compounds that are environmentally safe with low toxicity to wild life and humans. In this study novel organotin(IV) derivatives of bis(pyrimidin-2-ylthio)methane (ptm), bis(pyrimidin-2-ylthio)ethane (pte) and bis(pyrimidin-2-ylthio)hexane (pth) were tested against phytopathogens to evaluate their activity as potential fungicides. The bis(pyrimidin-2-ylthio)alkanes were not active in contrast with the organotin(IV) derivatives. The 5-coordinate triphenyltin(IV) derivatives were the most active compounds in a wide range of concentration. This study shows that the microorganisms were susceptible to the acid character of the organotin(IV) precursors.
VL  - 3
IS  - 2
ER  -

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Author Information

Fernanda Andrade Mendonça
Geraldo José da Silva Junior

Departamento de Fitopatologia, CCA / Universidade Federal de Vi?osa, 36570-900, Vi?osa, MG, Brasil
José Roberto da Silveira Maia

Departamento de Química, CCET / Universidade Federal de Vi?osa, 36570-900, Vi?osa, MG, Brasil
Onkar Dev Dhingra

Departamento de Fitopatologia, CCA / Universidade Federal de Vi?osa, 36570-900, Vi?osa, MG, Brasil
Rosimeire Coura Barcelos

Departamento de Química, CCET / Universidade Federal de Vi?osa, 36570-900, Vi?osa, MG, Brasil

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APA Style

Fernanda Andrade Mendonça, Geraldo José da Silva Junior, José Roberto da Silveira Maia, Onkar Dev Dhingra, Rosimeire Coura Barcelos. (2015). The Coordination Chemistry in the Antifungal Effect of Tin(IV)-Bis(Pyrimidin-2-Ylthio)Alkane Derivatives. American Journal of Applied Chemistry, 3(2), 77-82. https://doi.org/10.11648/j.ajac.20150302.17

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ACS Style

Fernanda Andrade Mendonça; Geraldo José da Silva Junior; José Roberto da Silveira Maia; Onkar Dev Dhingra; Rosimeire Coura Barcelos. The Coordination Chemistry in the Antifungal Effect of Tin(IV)-Bis(Pyrimidin-2-Ylthio)Alkane Derivatives. Am. J. Appl. Chem. 2015, 3(2), 77-82. doi: 10.11648/j.ajac.20150302.17

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AMA Style

Fernanda Andrade Mendonça, Geraldo José da Silva Junior, José Roberto da Silveira Maia, Onkar Dev Dhingra, Rosimeire Coura Barcelos. The Coordination Chemistry in the Antifungal Effect of Tin(IV)-Bis(Pyrimidin-2-Ylthio)Alkane Derivatives. Am J Appl Chem. 2015;3(2):77-82. doi: 10.11648/j.ajac.20150302.17

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@article{10.11648/j.ajac.20150302.17,
  author = {Fernanda Andrade Mendonça and Geraldo José da Silva Junior and José Roberto da Silveira Maia and Onkar Dev Dhingra and Rosimeire Coura Barcelos},
  title = {The Coordination Chemistry in the Antifungal Effect of Tin(IV)-Bis(Pyrimidin-2-Ylthio)Alkane Derivatives},
  journal = {American Journal of Applied Chemistry},
  volume = {3},
  number = {2},
  pages = {77-82},
  doi = {10.11648/j.ajac.20150302.17},
  url = {https://doi.org/10.11648/j.ajac.20150302.17},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajac.20150302.17},
  abstract = {High productivity of agriculture goods is closely associated with the use of fungicides to reduce losses caused by the fungal plant diseases. However, appearance of resistant population of pathogens to several commercial fungicides is a common phenomenon that requires control. There is, therefore, need for developing novel fungicide compounds that are environmentally safe with low toxicity to wild life and humans. In this study novel organotin(IV) derivatives of bis(pyrimidin-2-ylthio)methane (ptm), bis(pyrimidin-2-ylthio)ethane (pte) and bis(pyrimidin-2-ylthio)hexane (pth) were tested against phytopathogens to evaluate their activity as potential fungicides. The bis(pyrimidin-2-ylthio)alkanes were not active in contrast with the organotin(IV) derivatives. The 5-coordinate triphenyltin(IV) derivatives were the most active compounds in a wide range of concentration. This study shows that the microorganisms were susceptible to the acid character of the organotin(IV) precursors.},
 year = {2015}
}

Copy | Download

TY  - JOUR
T1  - The Coordination Chemistry in the Antifungal Effect of Tin(IV)-Bis(Pyrimidin-2-Ylthio)Alkane Derivatives
AU  - Fernanda Andrade Mendonça
AU  - Geraldo José da Silva Junior
AU  - José Roberto da Silveira Maia
AU  - Onkar Dev Dhingra
AU  - Rosimeire Coura Barcelos
Y1  - 2015/04/09
PY  - 2015
N1  - https://doi.org/10.11648/j.ajac.20150302.17
DO  - 10.11648/j.ajac.20150302.17
T2  - American Journal of Applied Chemistry
JF  - American Journal of Applied Chemistry
JO  - American Journal of Applied Chemistry
SP  - 77
EP  - 82
PB  - Science Publishing Group
SN  - 2330-8745
UR  - https://doi.org/10.11648/j.ajac.20150302.17
AB  - High productivity of agriculture goods is closely associated with the use of fungicides to reduce losses caused by the fungal plant diseases. However, appearance of resistant population of pathogens to several commercial fungicides is a common phenomenon that requires control. There is, therefore, need for developing novel fungicide compounds that are environmentally safe with low toxicity to wild life and humans. In this study novel organotin(IV) derivatives of bis(pyrimidin-2-ylthio)methane (ptm), bis(pyrimidin-2-ylthio)ethane (pte) and bis(pyrimidin-2-ylthio)hexane (pth) were tested against phytopathogens to evaluate their activity as potential fungicides. The bis(pyrimidin-2-ylthio)alkanes were not active in contrast with the organotin(IV) derivatives. The 5-coordinate triphenyltin(IV) derivatives were the most active compounds in a wide range of concentration. This study shows that the microorganisms were susceptible to the acid character of the organotin(IV) precursors.
VL  - 3
IS  - 2
ER  -

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