Patient Factors Influencing Adherence to ART Treatment among HIV/AIDS Patients in Embu Teaching and Referral Hospital Comprehensive Care Clinic
Science Journal of Public Health
Volume 4, Issue 5, September 2016, Pages: 375-380
Received: Jul. 18, 2016;
Accepted: Jul. 28, 2016;
Published: Aug. 17, 2016
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Evangeline Kananu Njue Mugoh, Department of Community Health, Kenyatta University, Nairobi, Kenya
Ephantus Kabiru, Department of Community Health, Kenyatta University, Nairobi, Kenya
Joyce Mwaniki, Department of Plant Sciences, Kenyatta University, Nairobi, Kenya
Adherence to antiretroviral therapy is a major predictor of the survival of individuals living with HIV/AIDS. Appropriate use of antiretroviral drugs (ARVs) has improved the health of many HIV positive individuals. The effectiveness of HIV treatment depends on sustenance of high levels of adherence to ARVs, however, ARV regimens are often complicated and can be affected by varying dosing schedules, failing to have proper dietary requirements and patients developing adverse effects. The main objective of this study was to determine patient’s demographic, social and economic factors influencing adherence to Anti-retroviral drugs among HIV/AIDS adult patients. A cross sectional study was carried out at Embu County Teaching and Referral Hospital in Kenya. Stratified random sampling was used to obtain relative proportion of male and female respondents. 332 HIV positive patients were chosen from a total of 1694 patients who were active in ART for more than one year. A semi-structured interview schedules was used to obtain information. The study revealed that almost half (48.2%) of the respondents had optimal adherence to ART treatment. 34.9% cited traveling as an hindrance to optimal adherence to treatment. Adherence to ART treatment was significantly associated with age of the respondents, marital status, main occupation and average monthly income of the respondents. The study recommends that HIV patients should be given more information on the importance of consistency and nearly perfect adherence to ART. The patients should be enlightened on the importance of carrying their ARV drugs even when going for short travels.
Evangeline Kananu Njue Mugoh,
Patient Factors Influencing Adherence to ART Treatment among HIV/AIDS Patients in Embu Teaching and Referral Hospital Comprehensive Care Clinic, Science Journal of Public Health.
Vol. 4, No. 5,
2016, pp. 375-380.
Christian Unge et al., "Long-Term Adherence to Antiretroviral Treatment and Program Drop-Out in a High-Risk Urban Setting in Sub-Saharan Africa: A Prospective Cohort Study," PLOS ONE, vol. 5, no. 10, p. e 13613, 2010, doi: 10.1371/journal.pone.0013613.
Michael L Scanlon and Rachel C Vreeman, "Current strategies for improving access and adherence to antiretroviral therapies in resource-limited settings," HIV AIDS, vol. 5, pp. 1–17, 2013.
World Health Organization [WHO], "From Access to Adherence: The Challenges of Antiretroviral Treatment - Studies from Botswana, Tanzania and Uganda," World Health Organization, Geneva, 2006.
Kaiser Family Foundation. (2015, July) Kaiser Family Foundation. [Online]. http://kff.org/global-health-policy/fact-sheet/the-global-hivaids-epidemic/#footnote-UNAIDSGlobalReport
UNAIDs. (2015) UNAIDs. [Online]. http://www.unaids.org/sites/default/files/media_asset/MDG6Report_en.pdf
NASCOP & NACC, "Kenya HIV County Profiles," Nairobi, 2014.
UNICEF. (2013, December) UNICEF Kenya. [Online]. http://www.unicef.org/infobycountry/kenya_statistics.html
Avert. (2015) Avert. [Online]. http://www.avert.org/professionals/hiv-around-world/sub-saharan-africa/kenya
NACC, "Kenya AIDS Strategic Framework 2014/2015 - 2018/2019," National AIDS Control Council, Ministry of Health, 2014.
NACC, "Kenya AIDS Response Progress Report 2014: Progress towards Zero," Nairobi, 2014.
NASCOP, "Kenya HIV Estimates: June 2014," Nairobi, 2014.
C. Shumba, L. Atuhaire, R. Imakit, R. Atukunda, and P. Memiah, "Missed Doses and Missed Appointments: Adherence to ART among Adult Patients in Uganda," International Scholarly Research Notices, vol. 2013, no. 2013, 2013.
Joyce Kgatlwane et al., "Factors that facilitate or constrain adherence to antiretroviral therapy among adults at four public health facilities in Botswana: a pre-intervention study," 2006.
Mathieu Rougemont, Beat E Stoll, Nadia Elia, and Peter Ngang, "Antiretroviral treatment adherence and its determinants in Sub-Saharan Africa: a prospective study at Yaounde Central Hospital, Cameroon," AIDS Research and Therapy, vol. 6, no. 21, October 2009.
Daniel P. Kidder et al., "HIV Prevention in Care and Treatment Settings: Baseline Risk Behaviors among HIV Patients in Kenya, Namibia, and Tanzania," PLoS ONE, vol. 8, no. 2, p. e 57215, February 2013.
Sarah Wangui Karanja, "Factors Influencing Adherence to Antiretroviral Medications Among Patients Living With HIV in Kenya," Department of Sociology and Social Work, University of Nairobi, Thesis 2013.
N. C Talam, P. Gatongi, J. Rotich, and S. Kimaiyo, "Factors Affecting Antiretroviral Drug Adherence Among HIV/AIDS Adult Patients Attending HIV/AIDS Clinic at Moi Teaching and Referral Hospital, Eldoret, Kenya.," East African Journal of Public Health, vol. 5, no. 2, pp. 74-78, August 2008.
Alemayehu Amberbir, Kifle Woldemichael, Sofonias Getachew, Belaineh Girma, and Kebede Deribe, "Predictors of adherence to antiretroviral therapy among HIV-infected persons: a prospective study in Southwest Ethiopia," BMC Public Health, vol. 8, no. 265, July 2008.
Heiko Karcher, Austin Omondi, John Odera, Andrea Kunz, and Gundel Harms, "Risk factors for treatment denial and loss to follow-up in an antiretroviral treatment cohort in Kenya," Tropical Medicine & International Health, vol. 12, no. 5, pp. 687–694, May 2007.
Habtamu Mitiku, Tekabe Abdosh, and Zelalem Teklemariam, "Factors Affecting Adherence to Antiretroviral Treatment in Harari National Regional State, Eastern Ethiopia," ISRN AIDS, vol. 960954, 2013, doi: 10.1155/2013/960954.
Bentsi Sam Ophelia, "Factors That Constrain Adherence to Antiretroviral Therapy among HIV Positive Patients in the Sekondi-Takoradi Metropolis," School of Public Health, Kwame Nkrumah University of Science and Technology, Master's Thesis 2015.
Ogbochi McKinney, Naomi N. Modeste, Jerry W. Lee, Peter C. Gleason, and Gisele Maynard-Tucker, "Determinants of Antiretroviral Therapy Adherence among Women in Southern Malawi: Healthcare Providers’ Perspectives," AIDS Research and Treatment, vol. 2014, no. 2014, December 2014.
Bayew Tsega, Bhagavathula Akshaya Srikanth, and Zewdneh Shewamene, "Determinants of non-adherence to antiretroviral therapy in adult hospitalized patients, Northwest Ethiopia," Patient Prefer Adherence, vol. 9, pp. 373–380, 2015, doi: 10.2147/PPA.S 75876.
Patou Masika Musumari et al., "Food Insecurity is Associated with Increased Risk of Non-Adherence to Antiretroviral Therapy among HIV-Infected Adults in the Democratic Republic of Congo: A Cross-Sectional Study," PLoS ONE, vol. 9, no. 1, p. e 85327, 2014, doi: 10.1371/journal.pone.0085327.
Jean B Nachega et al., "Association between antiretroviral therapy adherence and employment status: systematic review and meta-analysis," Bulletin of the World Health Organization, vol. 93, no. 1, pp. 29–41, 2014, doi: 10.2471/BLT.14.138149.