The Systematic Use of Fibrin-Based Biological Adhesive to Prevent Leakage Due to Healing Defects in Rectal Anastomosis Significantly Reduces Costs
Journal of Surgery
Volume 3, Issue 2, April 2015, Pages: 12-17
Received: Mar. 30, 2015;
Accepted: Apr. 14, 2015;
Published: Apr. 30, 2015
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Jesús Lago Oliver, Surgery Department, University Hospital Gregorio Marañón, Madrid, Spain
Salvador Argudo Garijo, Surgery Department, Southeast University Hospital.Arganda del Rey, Madrid, Spain
Mauricio Burneo Estéves, Surgery Department, University Hospital Gregorio Marañón, Madrid, Spain
Marta Cuadrado Ayuso, Surgery Department, University Hospital Gregorio Marañón, Madrid, Spain
Fernando Turégano Fuentes, Surgery Department, University Hospital Gregorio Marañón, Madrid, Spain
Araceli Casado Gómez, Pharmacoeconomics & Outcomes Research Iberia, Madrid, Spain
Objective: To analyse hospital costs in the pre-, and intra- and post-operative periods associated with patients undergoing rectal resection with anastomosis, comparing the costs per patient with and without the use of fibrin-based biological adhesive(Tissucol Duo®). Methods: The cost analysis was designed with a subsample of 37 patients who underwent rectal anastomosis in a randomised, single-blind, controlled, parallel comparison between two groups, to evaluate the effectiveness of fibrin-based biological adhesive used to prevent anastomotic leakage. The total costs included diagnostic tests, laboratory tests, hospital stay, adhesive cost, surgery, reintervention and drug treatment. Results: The patients had a mean age of 64.33 years, with a higher proportion of men (62.2%). The study groups were homogeneous and comparable. The average total cost in the group with biological adhesive was€ 10,304.84 compared to € 17,845.12 in the group without biological adhesive. Significant differences were found in the average cost of reintervention between groups: € 119.76 with adhesive vs. € 639.20 for the control group. Conclusions: The total cost decreased by 42% in the group in which a biological adhesive was applied compared to the group in which the adhesive was not applied. This percentage represented a difference of € 7,540.28 in the total average cost per patient.
Jesús Lago Oliver,
Salvador Argudo Garijo,
Mauricio Burneo Estéves,
Marta Cuadrado Ayuso,
Fernando Turégano Fuentes,
Araceli Casado Gómez,
The Systematic Use of Fibrin-Based Biological Adhesive to Prevent Leakage Due to Healing Defects in Rectal Anastomosis Significantly Reduces Costs, Journal of Surgery.
Vol. 3, No. 2,
2015, pp. 12-17.
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