Journal of Surgery
Volume 3, Issue 2-1, March 2015, Pages: 31-35
Received: Feb. 7, 2015;
Accepted: Feb. 13, 2015;
Published: May 9, 2015
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Ashraf Hassan Mohammed, Faculty of Physical Therapy, Cairo University, Cairo, Egypt
Thirty patients (17 female and 13 males) with chronic diabetic foot ulceration, age ranged from 50 to 65 years (53.4+ 4.1years), were selected from outpatient clinic of Benha teaching hospitals, Egypt from April 2013 to March 2014. Aim: Foot ulceration is one of the most common and severe complications of diabetes. The aim of the current was to clarify the effectiveness of topical negative pressure as a non invasive treatment approach for diabetic ulcers. Methods: Patients were divided into two equal groups; the first group was the control group and treated by traditional dressing while the second one was treated by negative pressure. The treatment course was extended up to six weeks; dressing was changed daily for the first group and day after day for the second group. Assessment was carried out before starting the course and after six weeks of treatment for both groups. The ulcer volume assessment was done by using a 10 cm syringe filled by terramycin ointment, and the wound surface area by using a graded plastic sheet. Student t-test was used to analyze the gained data of wound volume and surface area. Results: There was a significant improvement in the wound volume and surface area in the negative pressure group than that of the control group. Conclusion: It could be concluded that topical negative pressure is an effective non-invasive method in treating chronic diabetic foot ulceration.
Ashraf Hassan Mohammed,
Role of Negative Pressure Therapy in Healing of Diabetic Foot Ulcers, Journal of Surgery. Special Issue: Postoperative Pain Syndrome.
Vol. 3, No. 2-1,
2015, pp. 31-35.
Venturi ML, Attinger CE, Mesbahi AN, Hess CL, and Graw KS. Mechanisms and clinical applications of the vacuum-assisted closure (VAC) device: a review. Am J Clin Dermatol2005; 6(3):185–194.
Wongworawat ,Schnall SB, Holtom , Moon C, and Schiller F. Negative Pressure Dressings as an Alternative Technique for the Treatment Of Infected Wounds. Clin Orthop Relat Res 2003; 414:45–48.
Armstrong D.G, Lavery L.A, and Boulton A.J.M. Negative pressure wound therapy via vacuum-assisted closure following partial foot amputation: what is the role of wound chronicity. International Wound Journal 2007; 4(1): 79–86.
Mendonca D.A: Negative-pressure wound therapy: a snapshot of the evidence .International Wound Journal 2006; 3(4): 261–271.
Beitz JM, and Bates-Jensen B. Algorithms, critical pathways, and computer software for wound care: contemporary status and future potential. Ostomy Wound Management 2001; 47:33–40.
Morykwas MJ, Argenta LC, Shelton-Brown EI, McGuirt W. Vacuum-assisted closure: a new method for wound control and treatment: animal studies and basic foundation. Ann Plast Surg. 1997; 38(6):553–562.
Fabian T.S., Kaufman H.J., Lett E.D. The evaluation of subatmospheric pressure and hyperbaric oxygen in ischemic full-thickness wound healing. Am Surg2000; 66:1136–43.
Gustafsson R, Johnsson P, Algotsson L, et al. Vacuum-assisted closure therapy guided by C-reactive protein level in patients with deep sternal wound infection. J Thorac Cardiovasc Surg 2002; 123:895–900.
Gray, M. and Peirce, B. Is negative pressure wound therapy effective for the management of chronic wounds?. Evidence based report card from the center for clinical investigation. JWOCN.2004; 31: 101‐105.
Joseph E, Hamori CA, Bergman S, and et al. A prospective randomised trial of vaccum-assisted closure versus standard therapy of chronic non-healing wounds. Wounds 2000; 3:60–7.
Eginton MT, Brown KR, Seabrook GR, Towne JB, and Cambria RA. A prospective randomized evaluation of negative-pressure wound dressing for diabetic foot wounds. Ann Vasc Surg. 2003; 17(6):645–649.
Borgquist, Ola, Ingemansson, Richard; Malmsjö, and Malin. Wound edge microvascular blood flow during negative-pressure wound therapy: examining the effects of pressures from 10 to 175 mmHg .Plastic & Reconstructive Surgery 2010; 125 (2): 502-509.
Lucas C., Classen J., Harrison D., and DeHaan R): Pressure ulcer surface area measurement using instant full scale photography and transparency tracings.adv skin wound care 2002; 15(1):17-23.
Frykberg, R.G., Zgonis, T., and Armstrong, D.G. Diabeticfootdisorders: A clinicalpracticeguideline. J. FootAnkle Surg.2006; 45: 50.
Lazarus G, CooperD, Knighton D, Margolis D,:Definitions and guidlinesforassessment of wounds and evaluation of healing. Archives of dermatology 1999; 130: 489-493.
Jeschke MG, Rose C, Angele P, Fuchtmeier B, Nerlich M.N, and Bolder U. Development of new reconstructive techniques: use of Integra in combination with fibrin glue and negative-pressure therapy for reconstruction of acute and chronic wounds. Plast Reconstr Surg 2004;113(2):525–530.
Peter D. A., et al: Comparison Of Negative Pressure Wound Therapy With Advanced Moist Wound Therapy In The Treatment of Diabetic Foot Ulcers: Diabetic Care 2008;31:631.
Vuerstaek J.D, Vainas T, Wuite J, Nelemans P, Neumans M.H, and Veraat J.C.:State of the art treatment of chroniclegulcers: A randomisedcontrolled trial comparingvaccum-assistedclosure (V.A.C.) withmodernwounddressing. J VascSurg 2006; 44(5):1029-37.
Armstrong DF, and Levary LA: Negativepressurwoundtherapyafterpartialdiabeticfootamputation: a multicenter, randomisedcontrolled trial. Lancet 2005; 366:1704-1710.