Oxidative Stress Attenuation in Hiv/Aids Patients on Antiretroviral Drugs by Calyx Juice of Hibiscus sabdariffa Linn (Malvaceae)

Franklin Nyenty Tabe; Nicolas Njintang Yanou; Armel Herve Nwabo Kamdje; Aurélie –Solange Agume Ntso

doi:doi:10.11648/j.jdmp.20150101.11

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Oxidative Stress Attenuation in Hiv/Aids Patients on Antiretroviral Drugs by Calyx Juice of Hibiscus sabdariffa Linn (Malvaceae)

Franklin Nyenty Tabe, Nicolas Njintang Yanou, Armel Herve Nwabo Kamdje, Aurélie –Solange Agume Ntso

Published in Journal of Diseases and Medicinal Plants (Volume 1, Issue 1)

Received: 19 April 2015 Accepted: 24 April 2015 Published: 30 April 2015

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Abstract

The present study was aimed at evaluating the in vivo antioxidant potential of Hibiscus sabdariffa Linnaeus calyx juice (foléré) in HIV/AIDS patients on antiretroviral therapy. In the study, 5g of dried calyces were decocted with 250 mL of fresh tap water at 95°C for 15 minutes. The experimental design was a case-control randomized blinded trial in which, 58 patients on antiretroviral drugs were divided into 2 groups age-and-sex-matched. The experimental group was served a glass of 250 mL calyx juice per day alongside their antiretroviral treatment while the control group was exclusively on antiretroviral drugs with no available placebo. The trial was run for three (3) months after which blood samples were analyzed for the biochemical aspartate aminotransferase (ASAT) and alanine aminotransferase ALAT) and the hematological CD4, white blood cells (WBCs), red blood cells (RBCs), and hemoglobin (HGB)] parameters. The results show an increase in RBCs and WBCs in the experimental group which on the other hand experienced a decrease in CD4 and HGB. The control group experienced a decrease in RBCs, less decrease in HGB, and a higher decrease in CD4, but with increased WBCs. There was a parallel increase in ALAT and ASAT in both groups, more elevated in the control group.

Published in	Journal of Diseases and Medicinal Plants (Volume 1, Issue 1)
DOI	10.11648/j.jdmp.20150101.11
Page(s)	1-7
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Oxidative stress, HIV/AIDS, Antiretroviral, Antioxidant, Hibiscus sabdariffa Lin

References

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APA Style

Franklin Nyenty Tabe, Nicolas Njintang Yanou, Armel Herve Nwabo Kamdje, Aurélie –Solange Agume Ntso. (2015). Oxidative Stress Attenuation in Hiv/Aids Patients on Antiretroviral Drugs by Calyx Juice of Hibiscus sabdariffa Linn (Malvaceae). Journal of Diseases and Medicinal Plants, 1(1), 1-7. https://doi.org/10.11648/j.jdmp.20150101.11

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ACS Style

Franklin Nyenty Tabe; Nicolas Njintang Yanou; Armel Herve Nwabo Kamdje; Aurélie –Solange Agume Ntso. Oxidative Stress Attenuation in Hiv/Aids Patients on Antiretroviral Drugs by Calyx Juice of Hibiscus sabdariffa Linn (Malvaceae). J. Dis. Med. Plants 2015, 1(1), 1-7. doi: 10.11648/j.jdmp.20150101.11

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AMA Style

Franklin Nyenty Tabe, Nicolas Njintang Yanou, Armel Herve Nwabo Kamdje, Aurélie –Solange Agume Ntso. Oxidative Stress Attenuation in Hiv/Aids Patients on Antiretroviral Drugs by Calyx Juice of Hibiscus sabdariffa Linn (Malvaceae). J Dis Med Plants. 2015;1(1):1-7. doi: 10.11648/j.jdmp.20150101.11

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@article{10.11648/j.jdmp.20150101.11,
  author = {Franklin Nyenty Tabe and Nicolas Njintang Yanou and Armel Herve Nwabo Kamdje and Aurélie –Solange Agume Ntso},
  title = {Oxidative Stress Attenuation in Hiv/Aids Patients on Antiretroviral Drugs by Calyx Juice of Hibiscus sabdariffa Linn (Malvaceae)},
  journal = {Journal of Diseases and Medicinal Plants},
  volume = {1},
  number = {1},
  pages = {1-7},
  doi = {10.11648/j.jdmp.20150101.11},
  url = {https://doi.org/10.11648/j.jdmp.20150101.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jdmp.20150101.11},
  abstract = {The present study was aimed at evaluating the in vivo antioxidant potential of Hibiscus sabdariffa Linnaeus calyx juice (foléré) in HIV/AIDS patients on antiretroviral therapy. In the study, 5g of dried calyces were decocted with 250 mL of fresh tap water at 95°C for 15 minutes. The experimental design was a case-control randomized blinded trial in which, 58 patients on antiretroviral drugs were divided into 2 groups age-and-sex-matched. The experimental group was served a glass of 250 mL calyx juice per day alongside their antiretroviral treatment while the control group was exclusively on antiretroviral drugs with no available placebo. The trial was run for three (3) months after which blood samples were analyzed for the biochemical aspartate aminotransferase (ASAT) and alanine aminotransferase ALAT) and the hematological CD4, white blood cells (WBCs), red blood cells (RBCs), and hemoglobin (HGB)] parameters. The results show an increase in RBCs and WBCs in the experimental group which on the other hand experienced a decrease in CD4 and HGB. The control group experienced a decrease in RBCs, less decrease in HGB, and a higher decrease in CD4, but with increased WBCs. There was a parallel increase in ALAT and ASAT in both groups, more elevated in the control group.},
 year = {2015}
}

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TY  - JOUR
T1  - Oxidative Stress Attenuation in Hiv/Aids Patients on Antiretroviral Drugs by Calyx Juice of Hibiscus sabdariffa Linn (Malvaceae)
AU  - Franklin Nyenty Tabe
AU  - Nicolas Njintang Yanou
AU  - Armel Herve Nwabo Kamdje
AU  - Aurélie –Solange Agume Ntso
Y1  - 2015/04/30
PY  - 2015
N1  - https://doi.org/10.11648/j.jdmp.20150101.11
DO  - 10.11648/j.jdmp.20150101.11
T2  - Journal of Diseases and Medicinal Plants
JF  - Journal of Diseases and Medicinal Plants
JO  - Journal of Diseases and Medicinal Plants
SP  - 1
EP  - 7
PB  - Science Publishing Group
SN  - 2469-8210
UR  - https://doi.org/10.11648/j.jdmp.20150101.11
AB  - The present study was aimed at evaluating the in vivo antioxidant potential of Hibiscus sabdariffa Linnaeus calyx juice (foléré) in HIV/AIDS patients on antiretroviral therapy. In the study, 5g of dried calyces were decocted with 250 mL of fresh tap water at 95°C for 15 minutes. The experimental design was a case-control randomized blinded trial in which, 58 patients on antiretroviral drugs were divided into 2 groups age-and-sex-matched. The experimental group was served a glass of 250 mL calyx juice per day alongside their antiretroviral treatment while the control group was exclusively on antiretroviral drugs with no available placebo. The trial was run for three (3) months after which blood samples were analyzed for the biochemical aspartate aminotransferase (ASAT) and alanine aminotransferase ALAT) and the hematological CD4, white blood cells (WBCs), red blood cells (RBCs), and hemoglobin (HGB)] parameters. The results show an increase in RBCs and WBCs in the experimental group which on the other hand experienced a decrease in CD4 and HGB. The control group experienced a decrease in RBCs, less decrease in HGB, and a higher decrease in CD4, but with increased WBCs. There was a parallel increase in ALAT and ASAT in both groups, more elevated in the control group.
VL  - 1
IS  - 1
ER  -

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Author Information

Franklin Nyenty Tabe

Department of Biomedical Science, Faculty of Science, University of Ngaoundere, Adamawa Region, Cameroon
Nicolas Njintang Yanou

Department of Biomedical Science, Faculty of Science, University of Ngaoundere, Adamawa Region, Cameroon; National School of Agro-Industrial Sciences (Ensai), University of Ngaoundere, Adamawa Region, Cameroon
Armel Herve Nwabo Kamdje

Department of Biomedical Science, Faculty of Science, University of Ngaoundere, Adamawa Region, Cameroon
Aurélie –Solange Agume Ntso

University Institut of Technology, Adamawa Region, Cameroon; The Ngaoundere Regional Hospital, Adamawa Region Cameroon

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APA Style

Franklin Nyenty Tabe, Nicolas Njintang Yanou, Armel Herve Nwabo Kamdje, Aurélie –Solange Agume Ntso. (2015). Oxidative Stress Attenuation in Hiv/Aids Patients on Antiretroviral Drugs by Calyx Juice of Hibiscus sabdariffa Linn (Malvaceae). Journal of Diseases and Medicinal Plants, 1(1), 1-7. https://doi.org/10.11648/j.jdmp.20150101.11

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ACS Style

Franklin Nyenty Tabe; Nicolas Njintang Yanou; Armel Herve Nwabo Kamdje; Aurélie –Solange Agume Ntso. Oxidative Stress Attenuation in Hiv/Aids Patients on Antiretroviral Drugs by Calyx Juice of Hibiscus sabdariffa Linn (Malvaceae). J. Dis. Med. Plants 2015, 1(1), 1-7. doi: 10.11648/j.jdmp.20150101.11

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AMA Style

Franklin Nyenty Tabe, Nicolas Njintang Yanou, Armel Herve Nwabo Kamdje, Aurélie –Solange Agume Ntso. Oxidative Stress Attenuation in Hiv/Aids Patients on Antiretroviral Drugs by Calyx Juice of Hibiscus sabdariffa Linn (Malvaceae). J Dis Med Plants. 2015;1(1):1-7. doi: 10.11648/j.jdmp.20150101.11

Copy | Download

@article{10.11648/j.jdmp.20150101.11,
  author = {Franklin Nyenty Tabe and Nicolas Njintang Yanou and Armel Herve Nwabo Kamdje and Aurélie –Solange Agume Ntso},
  title = {Oxidative Stress Attenuation in Hiv/Aids Patients on Antiretroviral Drugs by Calyx Juice of Hibiscus sabdariffa Linn (Malvaceae)},
  journal = {Journal of Diseases and Medicinal Plants},
  volume = {1},
  number = {1},
  pages = {1-7},
  doi = {10.11648/j.jdmp.20150101.11},
  url = {https://doi.org/10.11648/j.jdmp.20150101.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jdmp.20150101.11},
  abstract = {The present study was aimed at evaluating the in vivo antioxidant potential of Hibiscus sabdariffa Linnaeus calyx juice (foléré) in HIV/AIDS patients on antiretroviral therapy. In the study, 5g of dried calyces were decocted with 250 mL of fresh tap water at 95°C for 15 minutes. The experimental design was a case-control randomized blinded trial in which, 58 patients on antiretroviral drugs were divided into 2 groups age-and-sex-matched. The experimental group was served a glass of 250 mL calyx juice per day alongside their antiretroviral treatment while the control group was exclusively on antiretroviral drugs with no available placebo. The trial was run for three (3) months after which blood samples were analyzed for the biochemical aspartate aminotransferase (ASAT) and alanine aminotransferase ALAT) and the hematological CD4, white blood cells (WBCs), red blood cells (RBCs), and hemoglobin (HGB)] parameters. The results show an increase in RBCs and WBCs in the experimental group which on the other hand experienced a decrease in CD4 and HGB. The control group experienced a decrease in RBCs, less decrease in HGB, and a higher decrease in CD4, but with increased WBCs. There was a parallel increase in ALAT and ASAT in both groups, more elevated in the control group.},
 year = {2015}
}

Copy | Download

TY  - JOUR
T1  - Oxidative Stress Attenuation in Hiv/Aids Patients on Antiretroviral Drugs by Calyx Juice of Hibiscus sabdariffa Linn (Malvaceae)
AU  - Franklin Nyenty Tabe
AU  - Nicolas Njintang Yanou
AU  - Armel Herve Nwabo Kamdje
AU  - Aurélie –Solange Agume Ntso
Y1  - 2015/04/30
PY  - 2015
N1  - https://doi.org/10.11648/j.jdmp.20150101.11
DO  - 10.11648/j.jdmp.20150101.11
T2  - Journal of Diseases and Medicinal Plants
JF  - Journal of Diseases and Medicinal Plants
JO  - Journal of Diseases and Medicinal Plants
SP  - 1
EP  - 7
PB  - Science Publishing Group
SN  - 2469-8210
UR  - https://doi.org/10.11648/j.jdmp.20150101.11
AB  - The present study was aimed at evaluating the in vivo antioxidant potential of Hibiscus sabdariffa Linnaeus calyx juice (foléré) in HIV/AIDS patients on antiretroviral therapy. In the study, 5g of dried calyces were decocted with 250 mL of fresh tap water at 95°C for 15 minutes. The experimental design was a case-control randomized blinded trial in which, 58 patients on antiretroviral drugs were divided into 2 groups age-and-sex-matched. The experimental group was served a glass of 250 mL calyx juice per day alongside their antiretroviral treatment while the control group was exclusively on antiretroviral drugs with no available placebo. The trial was run for three (3) months after which blood samples were analyzed for the biochemical aspartate aminotransferase (ASAT) and alanine aminotransferase ALAT) and the hematological CD4, white blood cells (WBCs), red blood cells (RBCs), and hemoglobin (HGB)] parameters. The results show an increase in RBCs and WBCs in the experimental group which on the other hand experienced a decrease in CD4 and HGB. The control group experienced a decrease in RBCs, less decrease in HGB, and a higher decrease in CD4, but with increased WBCs. There was a parallel increase in ALAT and ASAT in both groups, more elevated in the control group.
VL  - 1
IS  - 1
ER  -

Copy | Download