Occupational Toxicological Characteristics of LLM-105 Explosives

Yu Weifei; Liao Longyu; Chen Feilan; He Mingzhong; Tan Dongmei; Fan Guijuan; Hao Shilong; Lu Huanchang

doi:doi:10.11648/j.ijee.20160103.15

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Occupational Toxicological Characteristics of LLM-105 Explosives

Yu Weifei, Liao Longyu, Chen Feilan, He Mingzhong, Tan Dongmei, Fan Guijuan, Hao Shilong, Lu Huanchang

Published in International Journal of Ecotoxicology and Ecobiology (Volume 1, Issue 3)

Received: 7 September 2016 Accepted: 12 October 2016 Published: 28 October 2016

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Abstract

LLM-105, a novel nitro-substituted explosive, was evaluated for its occupational toxicological characteristics. Acute oral toxicity tests showed that the maximum tolerated dose should be 8% concentration (gastric irrigation 20mL/kg) and the minimum lethal dose should be 10% (gastric irrigation 20mL/kg). Acute dermal toxicity tests showed that LD50 should be more than 2000 mg/kg. Acute eye irritation tests showed that only slight irritations were found. Skin sensitization tests showed that slight allergic reactions were found. It was suggested that LLM-105 should be generally slightly toxic under normal process which should be positive as preliminary evaluation for occupational protection.

Published in	International Journal of Ecotoxicology and Ecobiology (Volume 1, Issue 3)
DOI	10.11648/j.ijee.20160103.15
Page(s)	88-93
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

2, 6-diamino-3, 5-dinitropyrazine-l-oxide (LLM-105), Toxicological Evaluations, Occupational Toxicological Characteristics

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APA Style

Yu Weifei, Liao Longyu, Chen Feilan, He Mingzhong, Tan Dongmei, et al. (2016). Occupational Toxicological Characteristics of LLM-105 Explosives. International Journal of Ecotoxicology and Ecobiology, 1(3), 88-93. https://doi.org/10.11648/j.ijee.20160103.15

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ACS Style

Yu Weifei; Liao Longyu; Chen Feilan; He Mingzhong; Tan Dongmei, et al. Occupational Toxicological Characteristics of LLM-105 Explosives. Int. J. Ecotoxicol. Ecobiol. 2016, 1(3), 88-93. doi: 10.11648/j.ijee.20160103.15

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AMA Style

Yu Weifei, Liao Longyu, Chen Feilan, He Mingzhong, Tan Dongmei, et al. Occupational Toxicological Characteristics of LLM-105 Explosives. Int J Ecotoxicol Ecobiol. 2016;1(3):88-93. doi: 10.11648/j.ijee.20160103.15

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@article{10.11648/j.ijee.20160103.15,
  author = {Yu Weifei and Liao Longyu and Chen Feilan and He Mingzhong and Tan Dongmei and Fan Guijuan and Hao Shilong and Lu Huanchang},
  title = {Occupational Toxicological Characteristics of LLM-105 Explosives},
  journal = {International Journal of Ecotoxicology and Ecobiology},
  volume = {1},
  number = {3},
  pages = {88-93},
  doi = {10.11648/j.ijee.20160103.15},
  url = {https://doi.org/10.11648/j.ijee.20160103.15},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijee.20160103.15},
  abstract = {LLM-105, a novel nitro-substituted explosive, was evaluated for its occupational toxicological characteristics. Acute oral toxicity tests showed that the maximum tolerated dose should be 8% concentration (gastric irrigation 20mL/kg) and the minimum lethal dose should be 10% (gastric irrigation 20mL/kg). Acute dermal toxicity tests showed that LD50 should be more than 2000 mg/kg. Acute eye irritation tests showed that only slight irritations were found. Skin sensitization tests showed that slight allergic reactions were found. It was suggested that LLM-105 should be generally slightly toxic under normal process which should be positive as preliminary evaluation for occupational protection.},
 year = {2016}
}

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TY  - JOUR
T1  - Occupational Toxicological Characteristics of LLM-105 Explosives
AU  - Yu Weifei
AU  - Liao Longyu
AU  - Chen Feilan
AU  - He Mingzhong
AU  - Tan Dongmei
AU  - Fan Guijuan
AU  - Hao Shilong
AU  - Lu Huanchang
Y1  - 2016/10/28
PY  - 2016
N1  - https://doi.org/10.11648/j.ijee.20160103.15
DO  - 10.11648/j.ijee.20160103.15
T2  - International Journal of Ecotoxicology and Ecobiology
JF  - International Journal of Ecotoxicology and Ecobiology
JO  - International Journal of Ecotoxicology and Ecobiology
SP  - 88
EP  - 93
PB  - Science Publishing Group
SN  - 2575-1735
UR  - https://doi.org/10.11648/j.ijee.20160103.15
AB  - LLM-105, a novel nitro-substituted explosive, was evaluated for its occupational toxicological characteristics. Acute oral toxicity tests showed that the maximum tolerated dose should be 8% concentration (gastric irrigation 20mL/kg) and the minimum lethal dose should be 10% (gastric irrigation 20mL/kg). Acute dermal toxicity tests showed that LD50 should be more than 2000 mg/kg. Acute eye irritation tests showed that only slight irritations were found. Skin sensitization tests showed that slight allergic reactions were found. It was suggested that LLM-105 should be generally slightly toxic under normal process which should be positive as preliminary evaluation for occupational protection.
VL  - 1
IS  - 3
ER  -

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Author Information

Yu Weifei

Laboratory of Energetic Materials, Institute of Chemical Materials, China Academy of Engineering Physics, Mianyang, China
Liao Longyu

Laboratory of Energetic Materials, Institute of Chemical Materials, China Academy of Engineering Physics, Mianyang, China
Chen Feilan

Center of Experimental Animals, Chongqing Medical University, Chongqing, China
He Mingzhong

Center of Experimental Animals, Chongqing Medical University, Chongqing, China
Tan Dongmei

Center of Experimental Animals, Chongqing Medical University, Chongqing, China
Fan Guijuan

Laboratory of Energetic Materials, Institute of Chemical Materials, China Academy of Engineering Physics, Mianyang, China
Hao Shilong

Laboratory of Energetic Materials, Institute of Chemical Materials, China Academy of Engineering Physics, Mianyang, China
Lu Huanchang

Laboratory of Energetic Materials, Institute of Chemical Materials, China Academy of Engineering Physics, Mianyang, China

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Plain Text BibTeX RIS

APA Style

Yu Weifei, Liao Longyu, Chen Feilan, He Mingzhong, Tan Dongmei, et al. (2016). Occupational Toxicological Characteristics of LLM-105 Explosives. International Journal of Ecotoxicology and Ecobiology, 1(3), 88-93. https://doi.org/10.11648/j.ijee.20160103.15

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ACS Style

Yu Weifei; Liao Longyu; Chen Feilan; He Mingzhong; Tan Dongmei, et al. Occupational Toxicological Characteristics of LLM-105 Explosives. Int. J. Ecotoxicol. Ecobiol. 2016, 1(3), 88-93. doi: 10.11648/j.ijee.20160103.15

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AMA Style

Yu Weifei, Liao Longyu, Chen Feilan, He Mingzhong, Tan Dongmei, et al. Occupational Toxicological Characteristics of LLM-105 Explosives. Int J Ecotoxicol Ecobiol. 2016;1(3):88-93. doi: 10.11648/j.ijee.20160103.15

Copy | Download

@article{10.11648/j.ijee.20160103.15,
  author = {Yu Weifei and Liao Longyu and Chen Feilan and He Mingzhong and Tan Dongmei and Fan Guijuan and Hao Shilong and Lu Huanchang},
  title = {Occupational Toxicological Characteristics of LLM-105 Explosives},
  journal = {International Journal of Ecotoxicology and Ecobiology},
  volume = {1},
  number = {3},
  pages = {88-93},
  doi = {10.11648/j.ijee.20160103.15},
  url = {https://doi.org/10.11648/j.ijee.20160103.15},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijee.20160103.15},
  abstract = {LLM-105, a novel nitro-substituted explosive, was evaluated for its occupational toxicological characteristics. Acute oral toxicity tests showed that the maximum tolerated dose should be 8% concentration (gastric irrigation 20mL/kg) and the minimum lethal dose should be 10% (gastric irrigation 20mL/kg). Acute dermal toxicity tests showed that LD50 should be more than 2000 mg/kg. Acute eye irritation tests showed that only slight irritations were found. Skin sensitization tests showed that slight allergic reactions were found. It was suggested that LLM-105 should be generally slightly toxic under normal process which should be positive as preliminary evaluation for occupational protection.},
 year = {2016}
}

Copy | Download

TY  - JOUR
T1  - Occupational Toxicological Characteristics of LLM-105 Explosives
AU  - Yu Weifei
AU  - Liao Longyu
AU  - Chen Feilan
AU  - He Mingzhong
AU  - Tan Dongmei
AU  - Fan Guijuan
AU  - Hao Shilong
AU  - Lu Huanchang
Y1  - 2016/10/28
PY  - 2016
N1  - https://doi.org/10.11648/j.ijee.20160103.15
DO  - 10.11648/j.ijee.20160103.15
T2  - International Journal of Ecotoxicology and Ecobiology
JF  - International Journal of Ecotoxicology and Ecobiology
JO  - International Journal of Ecotoxicology and Ecobiology
SP  - 88
EP  - 93
PB  - Science Publishing Group
SN  - 2575-1735
UR  - https://doi.org/10.11648/j.ijee.20160103.15
AB  - LLM-105, a novel nitro-substituted explosive, was evaluated for its occupational toxicological characteristics. Acute oral toxicity tests showed that the maximum tolerated dose should be 8% concentration (gastric irrigation 20mL/kg) and the minimum lethal dose should be 10% (gastric irrigation 20mL/kg). Acute dermal toxicity tests showed that LD50 should be more than 2000 mg/kg. Acute eye irritation tests showed that only slight irritations were found. Skin sensitization tests showed that slight allergic reactions were found. It was suggested that LLM-105 should be generally slightly toxic under normal process which should be positive as preliminary evaluation for occupational protection.
VL  - 1
IS  - 3
ER  -

Copy | Download