American Journal of Biomedical and Life Sciences

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Hepatitis B and C Single and Co-Infection Patterns Among Emergency Patients in a Resource-Limited Setting

Received: 09 April 2015    Accepted: 18 April 2015    Published: 09 May 2015
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Abstract

Background: Hepatitis B and C viral infections continue to constitute major global health problems and are responsible for most liver related deaths. This study is carried out to reveal the hepatitis B and C single and co-infection patterns among emergency patients and their possible liver outcomes. Methods: Two hundred and eighty-eight (288) patients on initial visit from casualty unit were routinely screened for hepatitis B and C viruses over a period of two years in the haematology department. Diaspot one step enzyme immunoassay rapid kits for hepatitis B surface antigen (HBsAg) and anti-HCV respectively were used. HBsAg and anti-HCV seroprevalence and possible co-infections were evaluated using descriptive statistics of SPSS version 17 and expressed in mean and standard deviation, and male: female ratios. Results: Of the 288 research volunteers, 8.68% and 1.74% were positive for HBsAg and anti-HCV respectively. 1.04% was HBV and HCV co-infected. The overall mean age and male: female ratio were 44.4±17.3 years and 1.4:1 respectively. Lower mean age and higher male: female ratios were observed in HBV and HCV population. HCC remain the major liver outcome in HBV-infected and HBV/HCV co-infected research subjects. Conclusion: Hepatitis B and C viral infections still remain a major public health problem globally. There is need for continued aggressive advocacy on ‘Know your HBV and HCV status’ to reduce the scourge of these infections especially in rural and resource-limited settings where problem of poverty and ignorance have contributed to development of liver complications in these patients.

DOI 10.11648/j.ajbls.20150303.15
Published in American Journal of Biomedical and Life Sciences (Volume 3, Issue 3, June 2015)
Page(s) 55-60
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

HBsAg, Anti-HCV, HCC, Seroprevalence, Male: Female Ratios, Gender Differences

References
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Author Information
  • Department of Haematology, Federal Teaching Hospital, Ido Ekiti, Nigeria

  • Department of Pharmacology and Therapeutics, Afe Babalola University, Ado Ekiti, Nigeria

  • Department of Haematology, Federal Teaching Hospital, Ido Ekiti, Nigeria

  • Department of Haematology, Federal Teaching Hospital, Ido Ekiti, Nigeria

  • Department of Family Medicine, Federal Teaching Hospital, Ido Ekiti, Nigeria

  • Department of Medical Laboratory Science, Afe Babalola University, Ado Ekiti, Nigeria

  • Department of Haematology and Immunology, College of Health Sciences, Obafemi Awolowo University, Ile Ife, Nigeria

Cite This Article
  • APA Style

    Fasakin Kolawole Asimiyu, Ajayi Oluwafemi David, Esan Ayodele Jacob, Omisakin Christopher Tope, Adams Olusegun Timothy, et al. (2015). Hepatitis B and C Single and Co-Infection Patterns Among Emergency Patients in a Resource-Limited Setting. American Journal of Biomedical and Life Sciences, 3(3), 55-60. https://doi.org/10.11648/j.ajbls.20150303.15

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    ACS Style

    Fasakin Kolawole Asimiyu; Ajayi Oluwafemi David; Esan Ayodele Jacob; Omisakin Christopher Tope; Adams Olusegun Timothy, et al. Hepatitis B and C Single and Co-Infection Patterns Among Emergency Patients in a Resource-Limited Setting. Am. J. Biomed. Life Sci. 2015, 3(3), 55-60. doi: 10.11648/j.ajbls.20150303.15

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    AMA Style

    Fasakin Kolawole Asimiyu, Ajayi Oluwafemi David, Esan Ayodele Jacob, Omisakin Christopher Tope, Adams Olusegun Timothy, et al. Hepatitis B and C Single and Co-Infection Patterns Among Emergency Patients in a Resource-Limited Setting. Am J Biomed Life Sci. 2015;3(3):55-60. doi: 10.11648/j.ajbls.20150303.15

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  • @article{10.11648/j.ajbls.20150303.15,
      author = {Fasakin Kolawole Asimiyu and Ajayi Oluwafemi David and Esan Ayodele Jacob and Omisakin Christopher Tope and Adams Olusegun Timothy and Ojiezeh Tony Ifeanyi and Aboderin Florence Ifechukwude},
      title = {Hepatitis B and C Single and Co-Infection Patterns Among Emergency Patients in a Resource-Limited Setting},
      journal = {American Journal of Biomedical and Life Sciences},
      volume = {3},
      number = {3},
      pages = {55-60},
      doi = {10.11648/j.ajbls.20150303.15},
      url = {https://doi.org/10.11648/j.ajbls.20150303.15},
      eprint = {https://download.sciencepg.com/pdf/10.11648.j.ajbls.20150303.15},
      abstract = {Background: Hepatitis B and C viral infections continue to constitute major global health problems and are responsible for most liver related deaths. This study is carried out to reveal the hepatitis B and C single and co-infection patterns among emergency patients and their possible liver outcomes. Methods: Two hundred and eighty-eight (288) patients on initial visit from casualty unit were routinely screened for hepatitis B and C viruses over a period of two years in the haematology department. Diaspot one step enzyme immunoassay rapid kits for hepatitis B surface antigen (HBsAg) and anti-HCV respectively were used. HBsAg and anti-HCV seroprevalence and possible co-infections were evaluated using descriptive statistics of SPSS version 17 and expressed in mean and standard deviation, and male: female ratios. Results: Of the 288 research volunteers, 8.68% and 1.74% were positive for HBsAg and anti-HCV respectively. 1.04% was HBV and HCV co-infected. The overall mean age and male: female ratio were 44.4±17.3 years and 1.4:1 respectively. Lower mean age and higher male: female ratios were observed in HBV and HCV population. HCC remain the major liver outcome in HBV-infected and HBV/HCV co-infected research subjects. Conclusion: Hepatitis B and C viral infections still remain a major public health problem globally. There is need for continued aggressive advocacy on ‘Know your HBV and HCV status’ to reduce the scourge of these infections especially in rural and resource-limited settings where problem of poverty and ignorance have contributed to development of liver complications in these patients.},
     year = {2015}
    }
    

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  • TY  - JOUR
    T1  - Hepatitis B and C Single and Co-Infection Patterns Among Emergency Patients in a Resource-Limited Setting
    AU  - Fasakin Kolawole Asimiyu
    AU  - Ajayi Oluwafemi David
    AU  - Esan Ayodele Jacob
    AU  - Omisakin Christopher Tope
    AU  - Adams Olusegun Timothy
    AU  - Ojiezeh Tony Ifeanyi
    AU  - Aboderin Florence Ifechukwude
    Y1  - 2015/05/09
    PY  - 2015
    N1  - https://doi.org/10.11648/j.ajbls.20150303.15
    DO  - 10.11648/j.ajbls.20150303.15
    T2  - American Journal of Biomedical and Life Sciences
    JF  - American Journal of Biomedical and Life Sciences
    JO  - American Journal of Biomedical and Life Sciences
    SP  - 55
    EP  - 60
    PB  - Science Publishing Group
    SN  - 2330-880X
    UR  - https://doi.org/10.11648/j.ajbls.20150303.15
    AB  - Background: Hepatitis B and C viral infections continue to constitute major global health problems and are responsible for most liver related deaths. This study is carried out to reveal the hepatitis B and C single and co-infection patterns among emergency patients and their possible liver outcomes. Methods: Two hundred and eighty-eight (288) patients on initial visit from casualty unit were routinely screened for hepatitis B and C viruses over a period of two years in the haematology department. Diaspot one step enzyme immunoassay rapid kits for hepatitis B surface antigen (HBsAg) and anti-HCV respectively were used. HBsAg and anti-HCV seroprevalence and possible co-infections were evaluated using descriptive statistics of SPSS version 17 and expressed in mean and standard deviation, and male: female ratios. Results: Of the 288 research volunteers, 8.68% and 1.74% were positive for HBsAg and anti-HCV respectively. 1.04% was HBV and HCV co-infected. The overall mean age and male: female ratio were 44.4±17.3 years and 1.4:1 respectively. Lower mean age and higher male: female ratios were observed in HBV and HCV population. HCC remain the major liver outcome in HBV-infected and HBV/HCV co-infected research subjects. Conclusion: Hepatitis B and C viral infections still remain a major public health problem globally. There is need for continued aggressive advocacy on ‘Know your HBV and HCV status’ to reduce the scourge of these infections especially in rural and resource-limited settings where problem of poverty and ignorance have contributed to development of liver complications in these patients.
    VL  - 3
    IS  - 3
    ER  - 

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