The Prevalence of Klebsiella Species Causing Urinary Tract Infections in Murtala Muhammad Specialist Hospital, Kano, Nigeria
American Journal of Biomedical and Life Sciences
Volume 4, Issue 2, April 2016, Pages: 11-15
Received: Feb. 13, 2016;
Accepted: Feb. 23, 2016;
Published: Mar. 16, 2016
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Hamza Sule, Department of Medical Laboratory Science, Faculty of Allied Health Sciences, Bayero University, Kano, Nigeria
Abdulhadi Sale Kumurya, Department of Medical Laboratory Science, Faculty of Allied Health Sciences, Bayero University, Kano, Nigeria
Urinary tract infections (UTIs) are among the most commonly encountered infections, both in the community and in hospitals. The study investigated the Prevalence of Klebsiella species among patients suspected of UTI in Murtala Muhammad Specialist Hospital, Kano, Nigeria. Two hundred urine specimens of patients comparing of 135(67.5%) outpatients and 65(32.5%) inpatients and classified into 125(62.5%) females and 75(37.5%) males were bacteriologically evaluated. A total of 61(30.5%) yielded significant growth on culture of which 50(25%) were from females and 11(5.5%) from males. The age distribution of the patients with significant bacterial growth showed that patients within the age group of 21-30 years had the highest (UTI) cases of 33(16.5%) but those within the age group of less or equal to 10 years and those within the 51 to 60 years age bracket had 3(1.5%) UTI cases each. Of the uropathogens isolated, Escherichia coli was the most frequent organism responsible for UTI with 29((14.5%), followed by Klebsiella species with 16(8.0%). Other organisms isolated were Staphylococcus species 9(4.5%), proteus species 5(2.5%) and Pseudomonas species 2(1.0%) respectively. The speciation of Klebsiella species isolated `showed that 14(7.0%) were Klebsiella pneumoniae and 2(1.0%) were Klebsiella oxytoca. The antibiotic susceptibility testing for Klebsiella species isolates showed Ofloxacin as the best drug of choice with all the 16 isolates susceptible to Ofloxacin but at the same time all were resistant to ampicillin.
Abdulhadi Sale Kumurya,
The Prevalence of Klebsiella Species Causing Urinary Tract Infections in Murtala Muhammad Specialist Hospital, Kano, Nigeria, American Journal of Biomedical and Life Sciences.
Vol. 4, No. 2,
2016, pp. 11-15.
Sheiner, E. Mazor-Drey, E. and Levy, A. (2009). "Asymptomatic bacteriaria during pregnancy," J. Matem Fetal Neonatal Med. 22: 423–427.
John Delzell, J. and Michael, L.(2000). "Urinary tract infection during pregnancy," Am Fam, Physician. 61:713–720.
Weinstein, M. P. Towns, M. L. Quartey, S. M. (1997). The clinical significance of blood cultures in the 1990s: A prospective comprehensive evaluation of the microbiology, epidemiology and outcome of bacteraemia and fungemia in adults. Clin. Infect. Dis. 24:584-602.
Stamm, W. E. (2002). Scientific and Clinical Challenges in the Management of Urinary Tract Infections. Ame. J. Med. 113: 1s-4s.
Kolawole, A. S. Kolawole, O. M. Kandaki–Olukemi, Y. T. Babatunde, S. K. Durowade, K. A. Kolawole, C. F. (2009). Prevalence of urinary tract infections (UTI) among patients attending Dalhatu Araf Specialist Hospital, Lafia, Nasarawa State, Nigeria. Int. J. Medicinal Med. Sci. 1(5):163-167.
Patton, J. P. Nash, D. B. Abrutyn, E. (1991). Urinary tract infection: economic considerations. Med. Clin. North Am. 75:495-513.
Kunin, C. M. (1994). Urinary tract infections in females. Clinc. J. Infec. Dis. 18:1-12.
Aiyegoro, O. A. Igbinosa, O. O. Ogunmwonyi, I. N. Odjadjare, E. E. Igbinosa, O. E. Okoh, A. I (2007). Incidence of urinary tract infections (UTI) among children and adolescents in Ile-Ife, Nigeria. Afr. J. Microbiol. Res. 013-019.
Olowu, W.A. (1996). The office of Urinary Tract Infection and Vesicoureteral reflux in children, USA. Urol. Clin. North Am. 25 (4): 25-34.
Foxman B, Brown P. (2003). Epidemiology of urinary tract infections: transmission and risk factors, incidence, and costs. Infect Dis Clin North Am. 17(2): 227-24.
Ebie, M. Y. Kandakai-Olukemi, Y. T. Ayanbadejo, J. and Tanyigna, K. B. (2001). Urinary Tract Infections in a Nigerian Military Hospital, Nigerian. J. Microbiol; 15(1):31-37.
Mackey and McCartney, (1996). Tropical Medical Micrbiology 14th ed. Churchill Livingstone. London. Pp. 978.
Cheesebrough, M. (2000). Distric Laboratory Practice in Tropical Countries Low Price ed. Chambridge University Press. Pp. 434.
Kirby, W. Bauer, A. Sherris, J. and Truck, M. (1966). "Antibiotic susceptibility testing by a standardized single disc method," Am. J. Clin. Path. 45:493–496.
Hooton, T. M. (2000). Pathogenesis of urinary tract infection: an update. J Antimicrob Chemother. 46:S1–S.
Kais, K. Ghanima, (2006). Development of resistance of some Klebsiella species isolated locally from UTI to some Beta Lactam antibiotics. UM-Salama Science J. 3(4):694-701.
Raphael, M. M. Moghene, E. B. Emmanuel, E. O. Stephen, A. E. Onyinye, J. U. (2015). Prevalence of Urinary Tract Infections (UTI) Among Pregnant Women in University of Benin Teaching Hospital (UBTH) Benin City, Nigeria. Journal of Asian Scientific Research. 5(4):198-204.
Ojo, D. A. Akpan, I. and Mafiana, C. F. (2007). Asymptomatic and symptomatic urinary tract infection in a Nigerian community. asset Series B 6(1):32-39.
Ojo, D. A, Osuolale, K. O. and Mafiana, C. P. (2004). Prevalence of urinary tract infection among students in a Nigerian University. Proceedings of int’l conference on science and national dev.25th-28 Oct. (2004).
Obiogbolu, C. H. Okonko, I. O. Anyamere, C. O. Adedeji, A. O. Akanbi, A. O. Ogun, A. A. Ejembi, J. And faleye, T. O. C. (2009). Incidence of Urinary Tract Infections (UTIs) Among Pregnant Women in Akwa Metropolis, Southeastern Nigeria. Scientific Research and Essay 4(8):820-824.
Alex, B. Peter, M. S. Johnson, N. B. George, A. K. Richard-Kwabena, D. E. Patrick, A. Gyasi, O. Dennis, P. (2012). Asymptomatic urinary tract infections in pregnant women attending antenatal clinic in Cape Coast, Ghana. E3 Journal of Medical Research. 1(6):074-083. Available online at http://www.e3journals.org.
Namratha, W. N. (2015). Profile of Urinary Tract Infection and Quinolone Resistance among Escherichia coli and Klebsiella species isolates. Int. J. Curr. Microbiol. App. Sci 4(7):749-756.
Osazuwa, F. Mordi, R. M. Osazuwa, E. Taiwo. S. S. Alli, O. A. T. Ogbolu, D. O. Akanni, E. O. Anukam, K. C. (2010). Klebsiella has taken lead among uropathogens in University of Benin Teaching Hospital, Benin City, Nigeria-An observation. New York Science Journal. 3(11):61-64.
Agbagwa, O. E. Ifeanacho, Emeka, J. U. (2015). The Prevalence of UTI Pathogens in Urine Specimen Obtained from a Hospital in Rivers State Nigeria. Journal of Microbiology Research 5(5):143-148.
Ekrem, K. Dyar musadaq, S. Daham yousif, A. Dlzar bayz, R. and Faisal sharaf, Y. (2015). Identification of the bacterial types that cause urinary tract infection and antimicrobial susceptibility in Erbil, Iraq. Sky Journal of Microbiology Research. 3(1):011–014.
Acheampong, D. O. Boamponsem, L. K. and Feglo, P. K. (2011). Occurrence and species distribution of Klebsiella Isolates: A case study at Komfo Anokye teaching hospital (Kath) in Ghana. Advances in Applied Science Research. (4):187-193 www.pelagiaresearchlibrary.com.
Manikandan, C. and Amsath, A. (2013). Antibiotic susceptibility pattern of Klebsiella pneumoniae isolated from urine samples Int. J. Curr. Microbiol. App.Sci 2(8):330-337.
Avci, I. Y. Kilic, S. Acikel, C. H. (2006). Outpatient prescription of oral antibiotics in a training hospital in Turkey: Trends in the last decade. J Infect. 52(1):9–14.