American Journal of Biomedical and Life Sciences

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Effect of Pectin on the Activity of Pancreatic α-Amylase in Growing Rats with Lead Intoxication

Received: 13 August 2016    Accepted: 23 August 2016    Published: 09 September 2016
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Abstract

This study was conducted to know the effect of pectin on the α-amylase activity in the pancreas, intestine content and blood in growing rats with lead intoxication. After a single oral administration of lead acetate (80 mg/kg) to growing rats pectin was administered (400 mg/kg/12h) for 4 days. It is revealed that the administration of lead acetate causes an increase in pancreas weight, protein content in the pancreas and α-amylase activity in the pancreas and blood and reduced activity of the enzyme in the intestinal cavity in rats. Regular oral administration of pectin has a normalizing effect on pancreatic weight, protein content and on the level of the activity α-amylase in the pancreas, intestinal contents and blood in the 48-72 hours of observation in rats. These results support our suggestion about the possibility of the use of pectin for correcting of pancreatitis similar shifts at lead intoxication.

DOI 10.11648/j.ajbls.20160405.11
Published in American Journal of Biomedical and Life Sciences (Volume 4, Issue 5, October 2016)
Page(s) 69-74
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Rat, Lead Acetate, Pectin, α-Amylase, Pancreas

References
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Author Information
  • Department of Physiology and Neurobiology, National University of Uzbekistan, Tashkent, Uzbekistan

  • Department of Physiology and Neurobiology, National University of Uzbekistan, Tashkent, Uzbekistan

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    Lubov Salijanovna Kuchkarova, Gulchehkra Tengelbaevna Kudeshova. (2016). Effect of Pectin on the Activity of Pancreatic α-Amylase in Growing Rats with Lead Intoxication. American Journal of Biomedical and Life Sciences, 4(5), 69-74. https://doi.org/10.11648/j.ajbls.20160405.11

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    ACS Style

    Lubov Salijanovna Kuchkarova; Gulchehkra Tengelbaevna Kudeshova. Effect of Pectin on the Activity of Pancreatic α-Amylase in Growing Rats with Lead Intoxication. Am. J. Biomed. Life Sci. 2016, 4(5), 69-74. doi: 10.11648/j.ajbls.20160405.11

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    AMA Style

    Lubov Salijanovna Kuchkarova, Gulchehkra Tengelbaevna Kudeshova. Effect of Pectin on the Activity of Pancreatic α-Amylase in Growing Rats with Lead Intoxication. Am J Biomed Life Sci. 2016;4(5):69-74. doi: 10.11648/j.ajbls.20160405.11

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  • @article{10.11648/j.ajbls.20160405.11,
      author = {Lubov Salijanovna Kuchkarova and Gulchehkra Tengelbaevna Kudeshova},
      title = {Effect of Pectin on the Activity of Pancreatic α-Amylase in Growing Rats with Lead Intoxication},
      journal = {American Journal of Biomedical and Life Sciences},
      volume = {4},
      number = {5},
      pages = {69-74},
      doi = {10.11648/j.ajbls.20160405.11},
      url = {https://doi.org/10.11648/j.ajbls.20160405.11},
      eprint = {https://download.sciencepg.com/pdf/10.11648.j.ajbls.20160405.11},
      abstract = {This study was conducted to know the effect of pectin on the α-amylase activity in the pancreas, intestine content and blood in growing rats with lead intoxication. After a single oral administration of lead acetate (80 mg/kg) to growing rats pectin was administered (400 mg/kg/12h) for 4 days. It is revealed that the administration of lead acetate causes an increase in pancreas weight, protein content in the pancreas and α-amylase activity in the pancreas and blood and reduced activity of the enzyme in the intestinal cavity in rats. Regular oral administration of pectin has a normalizing effect on pancreatic weight, protein content and on the level of the activity α-amylase in the pancreas, intestinal contents and blood in the 48-72 hours of observation in rats. These results support our suggestion about the possibility of the use of pectin for correcting of pancreatitis similar shifts at lead intoxication.},
     year = {2016}
    }
    

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  • TY  - JOUR
    T1  - Effect of Pectin on the Activity of Pancreatic α-Amylase in Growing Rats with Lead Intoxication
    AU  - Lubov Salijanovna Kuchkarova
    AU  - Gulchehkra Tengelbaevna Kudeshova
    Y1  - 2016/09/09
    PY  - 2016
    N1  - https://doi.org/10.11648/j.ajbls.20160405.11
    DO  - 10.11648/j.ajbls.20160405.11
    T2  - American Journal of Biomedical and Life Sciences
    JF  - American Journal of Biomedical and Life Sciences
    JO  - American Journal of Biomedical and Life Sciences
    SP  - 69
    EP  - 74
    PB  - Science Publishing Group
    SN  - 2330-880X
    UR  - https://doi.org/10.11648/j.ajbls.20160405.11
    AB  - This study was conducted to know the effect of pectin on the α-amylase activity in the pancreas, intestine content and blood in growing rats with lead intoxication. After a single oral administration of lead acetate (80 mg/kg) to growing rats pectin was administered (400 mg/kg/12h) for 4 days. It is revealed that the administration of lead acetate causes an increase in pancreas weight, protein content in the pancreas and α-amylase activity in the pancreas and blood and reduced activity of the enzyme in the intestinal cavity in rats. Regular oral administration of pectin has a normalizing effect on pancreatic weight, protein content and on the level of the activity α-amylase in the pancreas, intestinal contents and blood in the 48-72 hours of observation in rats. These results support our suggestion about the possibility of the use of pectin for correcting of pancreatitis similar shifts at lead intoxication.
    VL  - 4
    IS  - 5
    ER  - 

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