American Journal of Health Research

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Determinants of None-Adherence to Antiretroviral Therapy among HIV-Infected Adults in Arba Minch General Hospital, Gamo Gofa Zone, Southern Ethiopia: A Case Control Study

Received: 19 August 2014    Accepted: 03 September 2014    Published: 20 September 2014
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Abstract

Background: Non-adherence to antiretroviral therapy is a major challenge to Acquired Immunodeficiency Syndrome (AIDS) care. For Antiretroviral Therapy (ART) to be effective, high level of adherence is required. In spite of this, there is no information on determinant none-adherence to antiretroviral therapy in the study area; therefore this study was conducted to identify predictors of none-adherence to antiretroviral therapy among People Living with HIV/AIDS (PLWHA) in Arba Minch General Hospital. Methods: Unmatched case-control study design was employed on 115 case and 347 controls. Non-adherence to ART is considered as case and adherence to ART is taken as control. Data was collected by using a structured pre-tested questionnaire and by using data abstraction format from ART registration chart. Binary logistic regression analysis was calculated to assess the presence and degree of association between dependent and independent variables; finally multivariate analysis was conducted to identify independent factors for none adherence. Result: From interviewed respondent majority of respondent 304(65.8%) were females and the rest 158(34.2%) were males. From all respondent 209(45%) were in age group 30-39 years. Factors like rural residence 6.30(3.01-13.15), PLWHA who has no family and community support 1.92(1.05-3.51), mobile phone adjusted odds ratio (AOR) 1.20(1.15-3.44)), alcohol drinker 5.88(2.86-12.09), malnutrition 2.83(1.18-6.77) and who consume low dietary diversity 7.18(3.43-15.04) and CD4 Count <250 cells/mm3 2.18(1.05-4.50) are the major identified significant factors for none adherence to ART treatment in the study area. Conclusion and recommendation: PLWHA, who has no family and community support, rural residence, not utilized mobile phone, alcohol drinker, under nutrition, who consume low dietary diversity and those with low CD4 count are major significant determinant factors for non-adherence to ART treatment. Therefore, the capacity to effectively manage the above critical factor is crucial in the success of antiretroviral therapy.

DOI 10.11648/j.ajhr.20140205.13
Published in American Journal of Health Research (Volume 2, Issue 5, September 2014)
Page(s) 234-240
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Non-Adherence, Antiretroviral Therapy, Case Control, Southern Ethiopia

References
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Author Information
  • Arba Minch University, Department of Public Health, Arba Minch Ethiopia

  • Addis Continental Institute of Public Health, Addis Ababa, Ethiopia

  • Arba Minch University, Department of Public Health, Arba Minch Ethiopia

  • Arba Minch University, Department of Public Health, Arba Minch Ethiopia

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    Belay Dagnaw Bitew, Yemane Berehane, Eskezyiaw Agedew Getahun, Direslgne Misker Abyu. (2014). Determinants of None-Adherence to Antiretroviral Therapy among HIV-Infected Adults in Arba Minch General Hospital, Gamo Gofa Zone, Southern Ethiopia: A Case Control Study. American Journal of Health Research, 2(5), 234-240. https://doi.org/10.11648/j.ajhr.20140205.13

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    Belay Dagnaw Bitew; Yemane Berehane; Eskezyiaw Agedew Getahun; Direslgne Misker Abyu. Determinants of None-Adherence to Antiretroviral Therapy among HIV-Infected Adults in Arba Minch General Hospital, Gamo Gofa Zone, Southern Ethiopia: A Case Control Study. Am. J. Health Res. 2014, 2(5), 234-240. doi: 10.11648/j.ajhr.20140205.13

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    AMA Style

    Belay Dagnaw Bitew, Yemane Berehane, Eskezyiaw Agedew Getahun, Direslgne Misker Abyu. Determinants of None-Adherence to Antiretroviral Therapy among HIV-Infected Adults in Arba Minch General Hospital, Gamo Gofa Zone, Southern Ethiopia: A Case Control Study. Am J Health Res. 2014;2(5):234-240. doi: 10.11648/j.ajhr.20140205.13

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  • @article{10.11648/j.ajhr.20140205.13,
      author = {Belay Dagnaw Bitew and Yemane Berehane and Eskezyiaw Agedew Getahun and Direslgne Misker Abyu},
      title = {Determinants of None-Adherence to Antiretroviral Therapy among HIV-Infected Adults in Arba Minch General Hospital, Gamo Gofa Zone, Southern Ethiopia: A Case Control Study},
      journal = {American Journal of Health Research},
      volume = {2},
      number = {5},
      pages = {234-240},
      doi = {10.11648/j.ajhr.20140205.13},
      url = {https://doi.org/10.11648/j.ajhr.20140205.13},
      eprint = {https://download.sciencepg.com/pdf/10.11648.j.ajhr.20140205.13},
      abstract = {Background: Non-adherence to antiretroviral therapy is a major challenge to Acquired Immunodeficiency Syndrome (AIDS) care. For Antiretroviral Therapy (ART) to be effective, high level of adherence is required. In spite of this, there is no information on determinant none-adherence to antiretroviral therapy in the study area; therefore this study was conducted to identify predictors of none-adherence to antiretroviral therapy among People Living with HIV/AIDS (PLWHA) in Arba Minch General Hospital. Methods: Unmatched case-control study design was employed on 115 case and 347 controls. Non-adherence to ART is considered as case and adherence to ART is taken as control. Data was collected by using a structured pre-tested questionnaire and by using data abstraction format from ART registration chart. Binary logistic regression analysis was calculated to assess the presence and degree of association between dependent and independent variables; finally multivariate analysis was conducted to identify independent factors for none adherence. Result: From interviewed respondent majority of respondent 304(65.8%) were females and the rest 158(34.2%) were males. From all respondent 209(45%) were in age group 30-39 years. Factors like rural residence 6.30(3.01-13.15), PLWHA who has no family and community support 1.92(1.05-3.51), mobile phone adjusted odds ratio (AOR) 1.20(1.15-3.44)), alcohol drinker 5.88(2.86-12.09), malnutrition 2.83(1.18-6.77) and who consume low dietary diversity 7.18(3.43-15.04) and CD4 Count <250 cells/mm3 2.18(1.05-4.50) are the major identified significant factors for none adherence to ART treatment in the study area. Conclusion and recommendation: PLWHA, who has no family and community support, rural residence, not utilized mobile phone, alcohol drinker, under nutrition, who consume low dietary diversity and those with low CD4 count are major significant determinant factors for non-adherence to ART treatment. Therefore, the capacity to effectively manage the above critical factor is crucial in the success of antiretroviral therapy.},
     year = {2014}
    }
    

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  • TY  - JOUR
    T1  - Determinants of None-Adherence to Antiretroviral Therapy among HIV-Infected Adults in Arba Minch General Hospital, Gamo Gofa Zone, Southern Ethiopia: A Case Control Study
    AU  - Belay Dagnaw Bitew
    AU  - Yemane Berehane
    AU  - Eskezyiaw Agedew Getahun
    AU  - Direslgne Misker Abyu
    Y1  - 2014/09/20
    PY  - 2014
    N1  - https://doi.org/10.11648/j.ajhr.20140205.13
    DO  - 10.11648/j.ajhr.20140205.13
    T2  - American Journal of Health Research
    JF  - American Journal of Health Research
    JO  - American Journal of Health Research
    SP  - 234
    EP  - 240
    PB  - Science Publishing Group
    SN  - 2330-8796
    UR  - https://doi.org/10.11648/j.ajhr.20140205.13
    AB  - Background: Non-adherence to antiretroviral therapy is a major challenge to Acquired Immunodeficiency Syndrome (AIDS) care. For Antiretroviral Therapy (ART) to be effective, high level of adherence is required. In spite of this, there is no information on determinant none-adherence to antiretroviral therapy in the study area; therefore this study was conducted to identify predictors of none-adherence to antiretroviral therapy among People Living with HIV/AIDS (PLWHA) in Arba Minch General Hospital. Methods: Unmatched case-control study design was employed on 115 case and 347 controls. Non-adherence to ART is considered as case and adherence to ART is taken as control. Data was collected by using a structured pre-tested questionnaire and by using data abstraction format from ART registration chart. Binary logistic regression analysis was calculated to assess the presence and degree of association between dependent and independent variables; finally multivariate analysis was conducted to identify independent factors for none adherence. Result: From interviewed respondent majority of respondent 304(65.8%) were females and the rest 158(34.2%) were males. From all respondent 209(45%) were in age group 30-39 years. Factors like rural residence 6.30(3.01-13.15), PLWHA who has no family and community support 1.92(1.05-3.51), mobile phone adjusted odds ratio (AOR) 1.20(1.15-3.44)), alcohol drinker 5.88(2.86-12.09), malnutrition 2.83(1.18-6.77) and who consume low dietary diversity 7.18(3.43-15.04) and CD4 Count <250 cells/mm3 2.18(1.05-4.50) are the major identified significant factors for none adherence to ART treatment in the study area. Conclusion and recommendation: PLWHA, who has no family and community support, rural residence, not utilized mobile phone, alcohol drinker, under nutrition, who consume low dietary diversity and those with low CD4 count are major significant determinant factors for non-adherence to ART treatment. Therefore, the capacity to effectively manage the above critical factor is crucial in the success of antiretroviral therapy.
    VL  - 2
    IS  - 5
    ER  - 

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