Effects of Shea Butter Based Diet on Hepatic and Renal Enzymes and Plasma Lipid Profile in Albino Rats
Advances in Biochemistry
Volume 2, Issue 5, October 2014, Pages: 80-84
Received: Oct. 24, 2014; Accepted: Nov. 11, 2014; Published: Nov. 20, 2014
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Malachi Oluwaseyi Israel, Department of Biochemistry, Faculty of Science, Ekiti State University, Ado-Ekiti, Nigeria
Ajayi Olubunmi Bolanle, Department of Biochemistry, Faculty of Science, Ekiti State University, Ado-Ekiti, Nigeria
Akomolafe Seun Funmiola, Department of Biochemistry, Faculty of Science, Ekiti State University, Ado-Ekiti, Nigeria
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The effect of feeding Shea butter based diet on plasma, liver and kidney enzymes as well as the plasma lipid profile was studied. Twenty one weaned male rats weighing 35g to 45g were divided into three groups: control, test one and test two, each containing seven rats. Control group was given feed containing soya bean oil as lipid source ad libitum. In test groups one and two, Shea butter in 5% and 15% (w/w) respectively, replaced soya bean oil. The feeding lasted for 28 days after which the rats were sacrificed and the plasma as well as tissue samples from liver and kidney were collected. From the plasma, lipid profile; aspartate and alanine aminotransferases, alkaline phosphatase and total protein were assayed. From the tissue samples, aspartate and alanine aminotransferases, alkaline phosphatase and total protein were assayed. Significant decrease (P < 0.05) was observed in the total cholesterol (TC), high density lipoprotein (HDL), low density lipoprotein (LDL) and Triglyceride (TG) upon feeding with Shea butter based diet. Feeding with Shea butter did not pose any threat to hepatic and renal tissues.
Shea Butter, Renal, Hepatic, Lipid Profile
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Malachi Oluwaseyi Israel, Ajayi Olubunmi Bolanle, Akomolafe Seun Funmiola, Effects of Shea Butter Based Diet on Hepatic and Renal Enzymes and Plasma Lipid Profile in Albino Rats, Advances in Biochemistry. Vol. 2, No. 5, 2014, pp. 80-84. doi: 10.11648/j.ab.20140205.15
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