Cathepsins B, L and H Splenocytes as the Secondary Antioxidant Systems in the Conditions of Carbonyl Stress

Fomina Maria Alekseevna; Abalenikhina Yulia Vladimirovna

doi:doi:10.11648/j.ab.20150301.12

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Cathepsins B, L and H Splenocytes as the Secondary Antioxidant Systems in the Conditions of Carbonyl Stress

Fomina Maria Alekseevna, Abalenikhina Yulia Vladimirovna

Published in Advances in Biochemistry (Volume 3, Issue 1)

Received: 19 December 2014 Accepted: 6 January 2015 Published: 27 January 2015

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Abstract

In the conditions of synthesis of nitrogen oxide deficit` modelling there is a growth of carbonyl derived proteins due to basic aldehyde- and keton-dinitrophenylhydrazones. After adding L-NAME into the incubation medium there appears aggravation of the carbonyl stress as the result of growth of oxidative stress secondary markers content and exhausting of reserve-adaptative resource. Activation of cathepsins L and H splenocytes takes place in response to oxidative modified proteins elaboration which is proved by our positive correlative conjunction.

Published in	Advances in Biochemistry (Volume 3, Issue 1)
DOI	10.11648/j.ab.20150301.12
Page(s)	5-8
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Carbonyl Derived Proteins, Cathepsins, Oxidative Stress, L-NAME

References

[1]	Barrett A.J., Kirschke H. (1981) Cathepsin B, cathepsin H, cathepsin L. Methods in Enzymol. 80, 535-561.
[2]	Davies K.J. (2001) Degradation of oxidized proteins by the 20S proteasome. Biochimie.- 2001. 83 (3/4), 301-310.
[3]	Levine R.L. et al. (1990) Determination of carbonyl content in oxidatively modified proteins. Methods Enzymol. 186. 464–478.
[4]	Ogino Keiki and Wang Da-Hong (2007) Biomarkers of Oxidative/NitrosativeStress:An Approach to Disease Prevention. Acta Med. Okayama. 61 (4), 181-189.
[5]	Rossner Pavel Jr. et al. (2007) Oxidative and nitrosative stress markers in bus drivers. Mutation Research. 617, 23–32.
[6]	Volkan Ergin et al. (2013) Carbonyl Stress in Aging Process: Role of Vitamins and Phytochemicals as Redox Regulators. Aging and Disease, 4 (5). P. 279-294

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APA Style

Fomina Maria Alekseevna, Abalenikhina Yulia Vladimirovna. (2015). Cathepsins B, L and H Splenocytes as the Secondary Antioxidant Systems in the Conditions of Carbonyl Stress. Advances in Biochemistry, 3(1), 5-8. https://doi.org/10.11648/j.ab.20150301.12

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ACS Style

Fomina Maria Alekseevna; Abalenikhina Yulia Vladimirovna. Cathepsins B, L and H Splenocytes as the Secondary Antioxidant Systems in the Conditions of Carbonyl Stress. Adv. Biochem. 2015, 3(1), 5-8. doi: 10.11648/j.ab.20150301.12

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AMA Style

Fomina Maria Alekseevna, Abalenikhina Yulia Vladimirovna. Cathepsins B, L and H Splenocytes as the Secondary Antioxidant Systems in the Conditions of Carbonyl Stress. Adv Biochem. 2015;3(1):5-8. doi: 10.11648/j.ab.20150301.12

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@article{10.11648/j.ab.20150301.12,
  author = {Fomina Maria Alekseevna and Abalenikhina Yulia Vladimirovna},
  title = {Cathepsins B, L and H Splenocytes as the Secondary Antioxidant Systems in the Conditions of Carbonyl Stress},
  journal = {Advances in Biochemistry},
  volume = {3},
  number = {1},
  pages = {5-8},
  doi = {10.11648/j.ab.20150301.12},
  url = {https://doi.org/10.11648/j.ab.20150301.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ab.20150301.12},
  abstract = {In the conditions of synthesis of nitrogen oxide deficit` modelling there is a growth of carbonyl derived proteins due to basic aldehyde- and keton-dinitrophenylhydrazones. After adding L-NAME into the incubation medium there appears aggravation of the carbonyl stress as the result of growth of oxidative stress secondary markers content and exhausting of reserve-adaptative resource. Activation of cathepsins L and H splenocytes takes place in response to oxidative modified proteins elaboration which is proved by our positive correlative conjunction.},
 year = {2015}
}

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TY  - JOUR
T1  - Cathepsins B, L and H Splenocytes as the Secondary Antioxidant Systems in the Conditions of Carbonyl Stress
AU  - Fomina Maria Alekseevna
AU  - Abalenikhina Yulia Vladimirovna
Y1  - 2015/01/27
PY  - 2015
N1  - https://doi.org/10.11648/j.ab.20150301.12
DO  - 10.11648/j.ab.20150301.12
T2  - Advances in Biochemistry
JF  - Advances in Biochemistry
JO  - Advances in Biochemistry
SP  - 5
EP  - 8
PB  - Science Publishing Group
SN  - 2329-0862
UR  - https://doi.org/10.11648/j.ab.20150301.12
AB  - In the conditions of synthesis of nitrogen oxide deficit` modelling there is a growth of carbonyl derived proteins due to basic aldehyde- and keton-dinitrophenylhydrazones. After adding L-NAME into the incubation medium there appears aggravation of the carbonyl stress as the result of growth of oxidative stress secondary markers content and exhausting of reserve-adaptative resource. Activation of cathepsins L and H splenocytes takes place in response to oxidative modified proteins elaboration which is proved by our positive correlative conjunction.
VL  - 3
IS  - 1
ER  -

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Author Information

Fomina Maria Alekseevna

Ryazan State Medical University named after academician I.P. Pavlov, Ryazan, Russia
Abalenikhina Yulia Vladimirovna

Ryazan State Medical University named after academician I.P. Pavlov, Ryazan, Russia

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APA Style

Fomina Maria Alekseevna, Abalenikhina Yulia Vladimirovna. (2015). Cathepsins B, L and H Splenocytes as the Secondary Antioxidant Systems in the Conditions of Carbonyl Stress. Advances in Biochemistry, 3(1), 5-8. https://doi.org/10.11648/j.ab.20150301.12

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ACS Style

Fomina Maria Alekseevna; Abalenikhina Yulia Vladimirovna. Cathepsins B, L and H Splenocytes as the Secondary Antioxidant Systems in the Conditions of Carbonyl Stress. Adv. Biochem. 2015, 3(1), 5-8. doi: 10.11648/j.ab.20150301.12

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AMA Style

Fomina Maria Alekseevna, Abalenikhina Yulia Vladimirovna. Cathepsins B, L and H Splenocytes as the Secondary Antioxidant Systems in the Conditions of Carbonyl Stress. Adv Biochem. 2015;3(1):5-8. doi: 10.11648/j.ab.20150301.12

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@article{10.11648/j.ab.20150301.12,
  author = {Fomina Maria Alekseevna and Abalenikhina Yulia Vladimirovna},
  title = {Cathepsins B, L and H Splenocytes as the Secondary Antioxidant Systems in the Conditions of Carbonyl Stress},
  journal = {Advances in Biochemistry},
  volume = {3},
  number = {1},
  pages = {5-8},
  doi = {10.11648/j.ab.20150301.12},
  url = {https://doi.org/10.11648/j.ab.20150301.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ab.20150301.12},
  abstract = {In the conditions of synthesis of nitrogen oxide deficit` modelling there is a growth of carbonyl derived proteins due to basic aldehyde- and keton-dinitrophenylhydrazones. After adding L-NAME into the incubation medium there appears aggravation of the carbonyl stress as the result of growth of oxidative stress secondary markers content and exhausting of reserve-adaptative resource. Activation of cathepsins L and H splenocytes takes place in response to oxidative modified proteins elaboration which is proved by our positive correlative conjunction.},
 year = {2015}
}

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TY  - JOUR
T1  - Cathepsins B, L and H Splenocytes as the Secondary Antioxidant Systems in the Conditions of Carbonyl Stress
AU  - Fomina Maria Alekseevna
AU  - Abalenikhina Yulia Vladimirovna
Y1  - 2015/01/27
PY  - 2015
N1  - https://doi.org/10.11648/j.ab.20150301.12
DO  - 10.11648/j.ab.20150301.12
T2  - Advances in Biochemistry
JF  - Advances in Biochemistry
JO  - Advances in Biochemistry
SP  - 5
EP  - 8
PB  - Science Publishing Group
SN  - 2329-0862
UR  - https://doi.org/10.11648/j.ab.20150301.12
AB  - In the conditions of synthesis of nitrogen oxide deficit` modelling there is a growth of carbonyl derived proteins due to basic aldehyde- and keton-dinitrophenylhydrazones. After adding L-NAME into the incubation medium there appears aggravation of the carbonyl stress as the result of growth of oxidative stress secondary markers content and exhausting of reserve-adaptative resource. Activation of cathepsins L and H splenocytes takes place in response to oxidative modified proteins elaboration which is proved by our positive correlative conjunction.
VL  - 3
IS  - 1
ER  -

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