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Heat Shock Protein 90 Alpha Genes Are Up-regulated by Acute Exercise

Received: 22 March 2017    Accepted: 15 April 2017    Published: 5 July 2017
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Abstract

This study was designed to further determine the expression pattern and role of heat shock protein 90 alpha genes in pre and post acute exercise amongst young male undergraduates in Nnewi, Nigeria. Twenty five (25) healthy young male undergraduate students with an average age of 24.3± 3 years and body mass index of 22.7± 1.8(Kg/m2) participated fully in the study. The subjects took part in an endurance race using the Bruce treadmill protocol for sub-maximal exercise for a maximum of 21 minutes. Blood samples were collected from the participants before commencement of the study, at 1 hour, 4 hours and 24 hours post exercise. Heat shock protein 90 alpha genes expression patterns were detected using reverse transcriptase polymerase chain reaction method. The expression pattern of heat shock protein 90 alpha genes was up-regulated at 1 hours post exercise and sustained till 24 hours post exercise at 200bp in all the exercised subjects when compared with the pre-exercise stage. Post exercise stress activates the release of heat shock protein 90 alpha genes which are needed to restore cellular homeostasis.

Published in Advances in Biochemistry (Volume 5, Issue 4)
DOI 10.11648/j.ab.20170504.11
Page(s) 57-60
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Acute Exercise, Heat Shock Protein 90 Alpha, Stress, Up-regulation

References
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  • APA Style

    Ehiaghe Friday Alfred, Digban Kester, Ehiaghe Imuetiyan Joy. (2017). Heat Shock Protein 90 Alpha Genes Are Up-regulated by Acute Exercise. Advances in Biochemistry, 5(4), 57-60. https://doi.org/10.11648/j.ab.20170504.11

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    ACS Style

    Ehiaghe Friday Alfred; Digban Kester; Ehiaghe Imuetiyan Joy. Heat Shock Protein 90 Alpha Genes Are Up-regulated by Acute Exercise. Adv. Biochem. 2017, 5(4), 57-60. doi: 10.11648/j.ab.20170504.11

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    AMA Style

    Ehiaghe Friday Alfred, Digban Kester, Ehiaghe Imuetiyan Joy. Heat Shock Protein 90 Alpha Genes Are Up-regulated by Acute Exercise. Adv Biochem. 2017;5(4):57-60. doi: 10.11648/j.ab.20170504.11

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  • @article{10.11648/j.ab.20170504.11,
      author = {Ehiaghe Friday Alfred and Digban Kester and Ehiaghe Imuetiyan Joy},
      title = {Heat Shock Protein 90 Alpha Genes Are Up-regulated by Acute Exercise},
      journal = {Advances in Biochemistry},
      volume = {5},
      number = {4},
      pages = {57-60},
      doi = {10.11648/j.ab.20170504.11},
      url = {https://doi.org/10.11648/j.ab.20170504.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ab.20170504.11},
      abstract = {This study was designed to further determine the expression pattern and role of heat shock protein 90 alpha genes in pre and post acute exercise amongst young male undergraduates in Nnewi, Nigeria. Twenty five (25) healthy young male undergraduate students with an average age of 24.3± 3 years and body mass index of 22.7± 1.8(Kg/m2) participated fully in the study. The subjects took part in an endurance race using the Bruce treadmill protocol for sub-maximal exercise for a maximum of 21 minutes. Blood samples were collected from the participants before commencement of the study, at 1 hour, 4 hours and 24 hours post exercise. Heat shock protein 90 alpha genes expression patterns were detected using reverse transcriptase polymerase chain reaction method. The expression pattern of heat shock protein 90 alpha genes was up-regulated at 1 hours post exercise and sustained till 24 hours post exercise at 200bp in all the exercised subjects when compared with the pre-exercise stage. Post exercise stress activates the release of heat shock protein 90 alpha genes which are needed to restore cellular homeostasis.},
     year = {2017}
    }
    

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  • TY  - JOUR
    T1  - Heat Shock Protein 90 Alpha Genes Are Up-regulated by Acute Exercise
    AU  - Ehiaghe Friday Alfred
    AU  - Digban Kester
    AU  - Ehiaghe Imuetiyan Joy
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    PY  - 2017
    N1  - https://doi.org/10.11648/j.ab.20170504.11
    DO  - 10.11648/j.ab.20170504.11
    T2  - Advances in Biochemistry
    JF  - Advances in Biochemistry
    JO  - Advances in Biochemistry
    SP  - 57
    EP  - 60
    PB  - Science Publishing Group
    SN  - 2329-0862
    UR  - https://doi.org/10.11648/j.ab.20170504.11
    AB  - This study was designed to further determine the expression pattern and role of heat shock protein 90 alpha genes in pre and post acute exercise amongst young male undergraduates in Nnewi, Nigeria. Twenty five (25) healthy young male undergraduate students with an average age of 24.3± 3 years and body mass index of 22.7± 1.8(Kg/m2) participated fully in the study. The subjects took part in an endurance race using the Bruce treadmill protocol for sub-maximal exercise for a maximum of 21 minutes. Blood samples were collected from the participants before commencement of the study, at 1 hour, 4 hours and 24 hours post exercise. Heat shock protein 90 alpha genes expression patterns were detected using reverse transcriptase polymerase chain reaction method. The expression pattern of heat shock protein 90 alpha genes was up-regulated at 1 hours post exercise and sustained till 24 hours post exercise at 200bp in all the exercised subjects when compared with the pre-exercise stage. Post exercise stress activates the release of heat shock protein 90 alpha genes which are needed to restore cellular homeostasis.
    VL  - 5
    IS  - 4
    ER  - 

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Author Information
  • Department of Hematology and Immunohematology, College of Health Sciences, Igbinedion University, Okada, Nigeria; Department of Medical Laboratory Science, College of Health Sciences, Igbinedion University, Okada, Nigeria; Lahor Research and Medical Centre, Benin City, Nigeria; Department of Medical Laboratory Science, Nnamdi Azikiwe University, Awka, Nigeria

  • Department of Medical Laboratory Science, College of Health Sciences, Igbinedion University, Okada, Nigeria

  • Lahor Research and Medical Centre, Benin City, Nigeria

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