Electrolyte Levels Analysis on Diabetes Mellitus Patients in Noongan Regional General Hospital, North Sulawesi, Indonesia
Advances in Biochemistry
Volume 5, Issue 4, December 2020, Pages: 54-60
Received: Oct. 16, 2020;
Accepted: Nov. 16, 2020;
Published: Nov. 19, 2020
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Diana Shintawati Purwanto, Department of Biochemistry, Faculty of Medicine, Sam Ratulangi University, Manado, Indonesia; Department of Clinical Laboratory, R. D Kandou Central General Hospital, Manado, Indonesia
Yanti Meilen Mewo, Department of Biochemistry, Faculty of Medicine, Sam Ratulangi University, Manado, Indonesia
Edmond Leonard Jim, Department of Cardiovascular Medicine, Faculty of Medicine, Sam Ratulangi University, Manado, Indonesia
Richardo Jordan Laloan, Clinical Clerkship Program, Faculty of Medicine, Sam Ratulangi University, Manado, Indonesia
Hessyani Patrisia Theodora Raranta, Department of Clinical Laboratory, R. D Kandou Central General Hospital, Manado, Indonesia
Billy Johnson Kepel, Department of Chemistry, Faculty of Medicine, Sam Ratulangi University, Manado, Indonesia
Diabetes mellitus is a metabolic disease characterized by hyperglycemia caused by defects in insulin secretion, insulin action, or both, that affect the action of insulin on the target tissue. North Sulawesi is in the top 5 of 34 provinces in Indonesia with the highest prevalence of diabetes mellitus, based on the results of the 2018 Basic Health Research. The relationship between blood glucose and electrolytes is very complex, so there are still few studies looking for the relationship between the two in diabetes mellitus patients. This study aimed to find out the association between electrolytes levels (serum sodium, potassium, chloride, and magnesium) and fasting blood glucose in type 2 diabetes mellitus patients. This cross-sectional study was conducted in April-September 2020 at Noongan Regional Hospital, North Sulawesi, Indonesia. Demographic data including age, sex, symptoms, and oral anti-diabetic medication/insulin administration were collected, and then physical examination including body mass index was carried out. The Kolmogorov-Smirnov and Spearman Rank tests were used for statistical analysis. There is an inverse correlation between fasting blood glucose and serum sodium, chloride, and magnesium, but not significant. As for potassium, there is a direct correlation, but also not significant. In conclusion, only potassium has a positive correlation with fasting blood glucose, while other electrolytes have a negative correlation, however all of correlations are not significant.
Diana Shintawati Purwanto,
Yanti Meilen Mewo,
Edmond Leonard Jim,
Richardo Jordan Laloan,
Hessyani Patrisia Theodora Raranta,
Billy Johnson Kepel,
Electrolyte Levels Analysis on Diabetes Mellitus Patients in Noongan Regional General Hospital, North Sulawesi, Indonesia, Advances in Biochemistry.
Vol. 5, No. 4,
2020, pp. 54-60.
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