Advances in Biochemistry

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Environmental Factors in Etiology of Gastric Cancer

Received: 30 August 2015    Accepted: 16 September 2015    Published: 26 September 2015
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Abstract

Among all the cancers Gastric cancer has been reported to be a highly prevalent malignancy In Kashmir valley, constitutes about 30%-40% of all malignancies. Cancer is consistently considered as significant environmental issue besides other etiological factors. In our study the incidence ratio among genders remained 3:1(male to female). More incidents were found in 60-64 years of age, 34.5% patients reported weight loss and the weight difference was about 10kg from stage I to Stage IV, 62% of the patients were illiterate, 59.5% of patients were from poor and middle class and 51% patients had faced the Water pollution. Major portion 53 %of patients belongs to farmers& house wives among these 38.6%, 12.2%, 8.4%, 21.6%& 18.8% had exposure to Pesticides/insecticides, Fungicides, Chemicals, Fertilizer, Manure respectively. At the time of diagnosis patients presented with multiple symptoms like dyspepsia 76.5%, loss of appetite 35.5% and vomiting 42.0%. On physical examination, anaemia was the most common sign and was present in 163 81.5%, ascites was 11.1%, epigastric mass in 9.9% Regarding distribution of cancer within the stomach, distal stomach was involved in 45.5%, proximal stomach in 42.0% of patients; Middle stomach and Whole stomach were involved in 6.0% each. Among the common symptom, ulceroproliferative type was seen in 35.5%, ulcerative lesions were 30% and infiltrative were in 7.0 %.Various perceptible effects during our study provides significant evidence to conclude that in gastric cancer etiology, environment plays an important role.

DOI 10.11648/j.ab.20150305.11
Published in Advances in Biochemistry (Volume 3, Issue 5, October 2015)
Page(s) 51-56
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Gastric Cancer, Environmental Pollution, Occupation, Farming, Socio-demographic Profile, Clinical Presentation

References
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Cite This Article
  • APA Style

    Showkat Ahmad Bhat, Manzoor R. Mir, Sabhiya Majid, Muneeb U. Rehman, Sonallah Kuchy, et al. (2015). Environmental Factors in Etiology of Gastric Cancer. Advances in Biochemistry, 3(5), 51-56. https://doi.org/10.11648/j.ab.20150305.11

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    ACS Style

    Showkat Ahmad Bhat; Manzoor R. Mir; Sabhiya Majid; Muneeb U. Rehman; Sonallah Kuchy, et al. Environmental Factors in Etiology of Gastric Cancer. Adv. Biochem. 2015, 3(5), 51-56. doi: 10.11648/j.ab.20150305.11

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    AMA Style

    Showkat Ahmad Bhat, Manzoor R. Mir, Sabhiya Majid, Muneeb U. Rehman, Sonallah Kuchy, et al. Environmental Factors in Etiology of Gastric Cancer. Adv Biochem. 2015;3(5):51-56. doi: 10.11648/j.ab.20150305.11

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  • @article{10.11648/j.ab.20150305.11,
      author = {Showkat Ahmad Bhat and Manzoor R. Mir and Sabhiya Majid and Muneeb U. Rehman and Sonallah Kuchy and Bilal Ahmad Sheikh and Ishraq Husain and Bhudev C. Das},
      title = {Environmental Factors in Etiology of Gastric Cancer},
      journal = {Advances in Biochemistry},
      volume = {3},
      number = {5},
      pages = {51-56},
      doi = {10.11648/j.ab.20150305.11},
      url = {https://doi.org/10.11648/j.ab.20150305.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ab.20150305.11},
      abstract = {Among all the cancers Gastric cancer has been reported to be a highly prevalent malignancy In Kashmir valley, constitutes about 30%-40% of all malignancies. Cancer is consistently considered as significant environmental issue besides other etiological factors. In our study the incidence ratio among genders remained 3:1(male to female). More incidents were found in 60-64 years of age, 34.5% patients reported weight loss and the weight difference was about 10kg from stage I to Stage IV, 62% of the patients were illiterate, 59.5% of patients were from poor and middle class and 51% patients had faced the Water pollution. Major portion 53 %of patients belongs to farmers& house wives among these 38.6%, 12.2%, 8.4%, 21.6%& 18.8% had exposure to Pesticides/insecticides, Fungicides, Chemicals, Fertilizer, Manure respectively. At the time of diagnosis patients presented with multiple symptoms like dyspepsia 76.5%, loss of appetite 35.5% and vomiting 42.0%. On physical examination, anaemia was the most common sign and was present in 163 81.5%, ascites was 11.1%, epigastric mass in 9.9% Regarding distribution of cancer within the stomach, distal stomach was involved in 45.5%, proximal stomach in 42.0% of patients; Middle stomach and Whole stomach were involved in 6.0% each. Among the common symptom, ulceroproliferative type was seen in 35.5%, ulcerative lesions were 30% and infiltrative were in 7.0 %.Various perceptible effects during our study provides significant evidence to conclude that in gastric cancer etiology, environment plays an important role.},
     year = {2015}
    }
    

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  • TY  - JOUR
    T1  - Environmental Factors in Etiology of Gastric Cancer
    AU  - Showkat Ahmad Bhat
    AU  - Manzoor R. Mir
    AU  - Sabhiya Majid
    AU  - Muneeb U. Rehman
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    AU  - Bilal Ahmad Sheikh
    AU  - Ishraq Husain
    AU  - Bhudev C. Das
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    PB  - Science Publishing Group
    SN  - 2329-0862
    UR  - https://doi.org/10.11648/j.ab.20150305.11
    AB  - Among all the cancers Gastric cancer has been reported to be a highly prevalent malignancy In Kashmir valley, constitutes about 30%-40% of all malignancies. Cancer is consistently considered as significant environmental issue besides other etiological factors. In our study the incidence ratio among genders remained 3:1(male to female). More incidents were found in 60-64 years of age, 34.5% patients reported weight loss and the weight difference was about 10kg from stage I to Stage IV, 62% of the patients were illiterate, 59.5% of patients were from poor and middle class and 51% patients had faced the Water pollution. Major portion 53 %of patients belongs to farmers& house wives among these 38.6%, 12.2%, 8.4%, 21.6%& 18.8% had exposure to Pesticides/insecticides, Fungicides, Chemicals, Fertilizer, Manure respectively. At the time of diagnosis patients presented with multiple symptoms like dyspepsia 76.5%, loss of appetite 35.5% and vomiting 42.0%. On physical examination, anaemia was the most common sign and was present in 163 81.5%, ascites was 11.1%, epigastric mass in 9.9% Regarding distribution of cancer within the stomach, distal stomach was involved in 45.5%, proximal stomach in 42.0% of patients; Middle stomach and Whole stomach were involved in 6.0% each. Among the common symptom, ulceroproliferative type was seen in 35.5%, ulcerative lesions were 30% and infiltrative were in 7.0 %.Various perceptible effects during our study provides significant evidence to conclude that in gastric cancer etiology, environment plays an important role.
    VL  - 3
    IS  - 5
    ER  - 

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Author Information
  • Division of Veterinary Biochemistry, Faculty of Veterinary Sciences & Animal Husbandry (F. V. Sc & AH), Sher-e-Kashmir University of Agricultural Sciences & Technology Kashmir (SKUAST-K), Shuhama, Alustang, Srinagar, Jammu & Kashmir, India

  • Division of Veterinary Biochemistry, Faculty of Veterinary Sciences & Animal Husbandry (F. V. Sc & AH), Sher-e-Kashmir University of Agricultural Sciences & Technology Kashmir (SKUAST-K), Shuhama, Alustang, Srinagar, Jammu & Kashmir, India

  • Department of Biochemistry Govt. Medical College Srinagar, Srinagar, Jammu & Kashmir, India

  • Division of Veterinary Biochemistry, Faculty of Veterinary Sciences & Animal Husbandry (F. V. Sc & AH), Sher-e-Kashmir University of Agricultural Sciences & Technology Kashmir (SKUAST-K), Shuhama, Alustang, Srinagar, Jammu & Kashmir, India

  • Department of Oncology, Govt. Medical College Srinagar, Srinagar, Jammu & Kashmir, India

  • Division of Veterinary Biochemistry, Faculty of Veterinary Sciences & Animal Husbandry (F. V. Sc & AH), Sher-e-Kashmir University of Agricultural Sciences & Technology Kashmir (SKUAST-K), Shuhama, Alustang, Srinagar, Jammu & Kashmir, India

  • Division of Veterinary Biochemistry, Faculty of Veterinary Sciences & Animal Husbandry (F. V. Sc & AH), Sher-e-Kashmir University of Agricultural Sciences & Technology Kashmir (SKUAST-K), Shuhama, Alustang, Srinagar, Jammu & Kashmir, India

  • Amity Institute of Molecular Medicine & Stem Cell Research (AIMMSCR), Amity University Uttar Pradesh Campus, Delhi, India

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