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Review Article: Xanthine Oxidoreductase-An Important Functional Component of Differentiation, Apoptosis and Aggressiveness of Tumors

Received: 29 September 2016    Accepted: 5 November 2016    Published: 17 December 2016
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Abstract

Xanthine oxidoreductase(XOR)plays an important role in many pathologies, such as tumors, chronic hypoxia, renal injury, hypertension and so on. In this article we mainly review the current research about the regulation of activity and gene expression of XOR, and its physiochemical property, organ distribution, changes in tumors and relation with the other diseases. We conclude that XOR is an important functional component of differentiation and apoptosis and diminished expression contributes to aggressiveness of tumors.

Published in Cell Biology (Volume 4, Issue 4)
DOI 10.11648/j.cb.20160404.11
Page(s) 24-30
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Xanthine Oxidoreductase, Differentiation, Apoptosis, Aggressiveness, Tumors

References
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    Yinghong Zhang, Hong Cheng, Jing Xu, Lan Lu. (2016). Review Article: Xanthine Oxidoreductase-An Important Functional Component of Differentiation, Apoptosis and Aggressiveness of Tumors. Cell Biology, 4(4), 24-30. https://doi.org/10.11648/j.cb.20160404.11

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    ACS Style

    Yinghong Zhang; Hong Cheng; Jing Xu; Lan Lu. Review Article: Xanthine Oxidoreductase-An Important Functional Component of Differentiation, Apoptosis and Aggressiveness of Tumors. Cell Biol. 2016, 4(4), 24-30. doi: 10.11648/j.cb.20160404.11

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    AMA Style

    Yinghong Zhang, Hong Cheng, Jing Xu, Lan Lu. Review Article: Xanthine Oxidoreductase-An Important Functional Component of Differentiation, Apoptosis and Aggressiveness of Tumors. Cell Biol. 2016;4(4):24-30. doi: 10.11648/j.cb.20160404.11

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  • @article{10.11648/j.cb.20160404.11,
      author = {Yinghong Zhang and Hong Cheng and Jing Xu and Lan Lu},
      title = {Review Article: Xanthine Oxidoreductase-An Important Functional Component of Differentiation, Apoptosis and Aggressiveness of Tumors},
      journal = {Cell Biology},
      volume = {4},
      number = {4},
      pages = {24-30},
      doi = {10.11648/j.cb.20160404.11},
      url = {https://doi.org/10.11648/j.cb.20160404.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cb.20160404.11},
      abstract = {Xanthine oxidoreductase(XOR)plays an important role in many pathologies, such as tumors, chronic hypoxia, renal injury, hypertension and so on. In this article we mainly review the current research about the regulation of activity and gene expression of XOR, and its physiochemical property, organ distribution, changes in tumors and relation with the other diseases. We conclude that XOR is an important functional component of differentiation and apoptosis and diminished expression contributes to aggressiveness of tumors.},
     year = {2016}
    }
    

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    T1  - Review Article: Xanthine Oxidoreductase-An Important Functional Component of Differentiation, Apoptosis and Aggressiveness of Tumors
    AU  - Yinghong Zhang
    AU  - Hong Cheng
    AU  - Jing Xu
    AU  - Lan Lu
    Y1  - 2016/12/17
    PY  - 2016
    N1  - https://doi.org/10.11648/j.cb.20160404.11
    DO  - 10.11648/j.cb.20160404.11
    T2  - Cell Biology
    JF  - Cell Biology
    JO  - Cell Biology
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    EP  - 30
    PB  - Science Publishing Group
    SN  - 2330-0183
    UR  - https://doi.org/10.11648/j.cb.20160404.11
    AB  - Xanthine oxidoreductase(XOR)plays an important role in many pathologies, such as tumors, chronic hypoxia, renal injury, hypertension and so on. In this article we mainly review the current research about the regulation of activity and gene expression of XOR, and its physiochemical property, organ distribution, changes in tumors and relation with the other diseases. We conclude that XOR is an important functional component of differentiation and apoptosis and diminished expression contributes to aggressiveness of tumors.
    VL  - 4
    IS  - 4
    ER  - 

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Author Information
  • Department of Nursing, Wuhan University of Science and Technology, Wuhan, China

  • Department of Nursing, Wuhan University of Science and Technology, Wuhan, China

  • Department of Nursing, Wuhan University of Science and Technology, Wuhan, China

  • Department of Nursing, Wuhan University of Science and Technology, Wuhan, China

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