Trends of Tuberculosis Treatment Outcomes at Mizan-Aman General Hospital, Southwest Ethiopia: A Retrospective Study
International Journal of Immunology
Volume 2, Issue 2, April 2014, Pages: 11-15
Received: Aug. 21, 2014;
Accepted: Aug. 27, 2014;
Published: Sep. 10, 2014
Views 3657 Downloads 328
Wegderese Sintayehu, Mizan-Aman General Hospital, Mizan, Ethiopia
Abebe Abera, Department of Nursing, Jimma University, Jimma, Ethiopia
Teklemichael Gebru, Department of Public Health, Aman Health Science College, Mizan, Ethiopia
Temesgen Fiseha, Mizan-Aman General Hospital, Mizan, Ethiopia
Background: TB continues to be a major public health problem in Ethiopia, which ranks seventh by estimated number of cases among the 22 TB high-burden countries. TB Treatment will only be effective if the patient completes the regimen which includes a combination of drugs recommended by the physicians. Incomplete treatment may result in prolonged excretion of bacteria which may lead to increased morbidity and mortality and spread of the disease. Objectives: to assess the trends of tuberculosis treatment outcomes at Mizan Aman General Hospital, Bench Maji Zone, Southwest Ethiopia, from September 2010 to August 2013. Methods: A retrospective study design was conducted at the TB clinic of Mizan general Hospital by analyzing the data of registered tuberculosis patients. The original case records were carefully reviewed, analyzed and interpreted to determine descriptive statistic such as frequencies and proportion of variables. The results of the study were presented using tables and line diagram. The study was approved ethically by Jimma University, college of public health and medical science, department of Nursing. Result: about 2043 TB patient record was retrieved in this study period from 2010- 2013. Of these, 1207 (58.00%) were males and 874 (42.00%) were females. The magnitude of TB case during the study period were smoothly declined in the first four consecutive six months 382, 312, 212 and 116, respectively, whereas in the fifth six month the TB case dramatically increased to 547 however in the last phase reduces to 472. During the study period 362 (17.72 %) completed the treatment, 79 (3.87 %) cured, 4 (0.20%) defaulted, 1575 (76.99%) transferred out to other health facility, 25 (1.22%) were died but no one could failed the treatment regimen. Conclusion: The trends of overall TB diagnosed cases were reduced in the first two years but it increases in the third year. The treatment outcomes; high in transfer out and low in cure rate was observed. Thus, Behavioral change communication education emphasized on early detection and treatment of TB cases is important strategies to reduce TB burden.
Trends of Tuberculosis Treatment Outcomes at Mizan-Aman General Hospital, Southwest Ethiopia: A Retrospective Study, International Journal of Immunology.
Vol. 2, No. 2,
2014, pp. 11-15.
World Health Organization. Global Tuberculosis Report 2013.WHO/HTM/TB/2013.11. Geneva, Switzerland: WHO, 2013. http://whqlibdoc.who.int/hq/2013/ WHO_HTM_TB_2013.11.pdf Accessed November 2013.
Dennis L. Kasper, Eugene Braunwald, Anthony Fauci, Stephen Hauser, Dan Longo, J. Larry Jameson. Harrison’s Principles of Internal Medicine. 17th ed. 2008.
HIV-Associated TB Facts 2013 [Internet]. World Health Organization; 2013. Available from: http://www.who.int/tb/challenges/hiv/
WHO World Health Organization Website. Global TB Report 2010. [Internet]. Available from: http://www.who.int/tb/country/data/download/en/index.html.
World Health Organization. Addressing poverty in TB control. WHO report 2005. WHO/HTM/TB/2005.352. Geneva, Switzerland: WHO, 2005. http://whqlibdoc.who.int/hq/2005/ WHO_HTM_TB_2005.352.pdf Accessed November 2013.
Thomas C (2002) A literature review of the problems of delayed presentation for treatment and non-completion of treatment for tuberculosis in less developed countries and ways of addressing these problems using particular implementations of the DOTS strategy. J Manag Med 16: 371–400.
Borgdroff, Floyd K and Broekmans JF. Intervention to reduce tuberculosis mortality and transmission in low- and middle-income countries. Bulletin on the World Health Organization 80, 217-227.
Brudney K & Dobkin J (1991) Resurgent tuberculosis in New York City: human immunodeficiency virus, homelessness, and the decline of tuberculosis control programs. The American Review of Respiratory Disease 144, 745–749.
Daniel OJ, Oladapo OT & Alausa OK (2006) Default from tuberculosis treatment programme in Sagamu, Nigeria. Nigerian Journal of Medicine 15, 63–67.
Sevim T, Atac G, Gungor G et al. (2002) Treatment outcome of relapse and defaulter pulmonary tuberculosis patients. The International Journal of Tuberculosis and Lung Disease 6, 320–325.
Liao et al. Assessing trends and predictors of tuberculosis in Taiwan. BMC Public Health. 2012, 12:29.
Demeke. Trend of Tuberculosis and Treatment Outcomes in Gambella Region with Special Emphasize on Gambella Regional Hospital, Western Ethiopia. J Mycobac Dis. 2013; 3(2).
Becerra MC, Freeman J, Bayona J, et al. Using treatment failure under effective directly observed short-course chemotherapy programs to identify patients with multidrug-resistant tuberculosis. Int J Tuberc Lung Dis 2000; 4: 108–14.
World Health Organization (2009) Global Tuberculosis Control. Addis Ababa, Ethiopia: Country Profile.
Bench Maji Zone 2010 Anual Report. 2011.
Yassin MA, Datiko DG, Tulloch O, Markos P, Aschalew M, et al. Innovative Community-Based Approaches Doubled Tuberculosis Case Notification and Improve Treatment Outcome in Southern Ethiopia. PLoS ONE. 2013, 8(5):
Tessema B, Muche A, Bekele A, Reissig D, Emmrich F, et al. (2009) Treatment outcome of tuberculosis patients at Gondar University Teaching Hospital, Northwest Ethiopia. A fve year retrospective study. BMC Public Health 9: 371
Federal Ministry of Health (FMOH) (2000) Planning and Programming Department. Health and Health Related Indicators. E.C, Addis Ababa, Ethiopia.
Getahun B, Ameni G, Biadgilign S, Medhin G () Mortality and associated risk factors in a cohort of tuberculosis patients treated under DOTS programme in Addis Ababa, Ethiopia, 2011. BMC Infect Dis 11: 127.
Fantahun Biadglegne , Berhanu Anagaw4 , Tewodros Debebe1 , Belay Anagaw5 et al
A retrospective study on the outcomes of tuberculosis treatment in Felege Hiwot Referral Hospital, Northwest Ethiopia,2013. International Journal of Medicine and Medical Sciences, 5(2): 85-91