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Helicobacter pylori Infection: Seroprevalence and Detection of H. Pylori IgG by Using ELISA

Received: 12 April 2015    Accepted: 16 April 2015    Published: 24 April 2015
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Abstract

Background: Helicobacter pylori (H. pylori), one of the most common bacterial pathogens of humans, colonizes the gastric mucosa. H. pylori is a major factor in inflammatory and malignant diseases of the gastrointestinal tract, where it appears to persist throughout the host's life unless the patient is treated. Materials and methods: A study population was carried out through 100 patients who had gastrointestinal symptoms in Hail region. Seroprevalence of Helicobacter pylori was carried out by detection of H. pylori IgG in patient serum by using Enzyme Linked Immunosorbant Assay (ELISA). Results: Among the patients, H. pylori positivity percentage was found to be (57%) (57/100) in our study. It was found that, the average age of the patient was (one to 70 years old), 68% of them were male and 32% female, the majority came from Hail city. Conclusion: high H.pylori positivity ration (57%), that obtained from these study indicates that H.pylori infection is still a common problem among people in Hail region-Saudi Arabia. The titer of IgG antibody to H.pylori in patient serum can be used as non-invasive tests for the presence of gastric H.pylori infection and gastritis.

Published in International Journal of Immunology (Volume 3, Issue 2)
DOI 10.11648/j.iji.20150302.12
Page(s) 21-26
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This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Helicobacter pylori, IgG, Seroprevalence, ELISA

References
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[20] Jones DM, Eldridge J, Fox AJ, Sethi P, Whorwell PJ. : Antibody to the gastric campylobacter-like organism ("Campylobacter pyloridis")-clinical correlations and distribution in the normal population. Y Med Microbiol 1986;22:57-62.
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  • APA Style

    Sarah Yousef Ahmed, Hesa Nazel Al Shammari. (2015). Helicobacter pylori Infection: Seroprevalence and Detection of H. Pylori IgG by Using ELISA. International Journal of Immunology, 3(2), 21-26. https://doi.org/10.11648/j.iji.20150302.12

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    ACS Style

    Sarah Yousef Ahmed; Hesa Nazel Al Shammari. Helicobacter pylori Infection: Seroprevalence and Detection of H. Pylori IgG by Using ELISA. Int. J. Immunol. 2015, 3(2), 21-26. doi: 10.11648/j.iji.20150302.12

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    AMA Style

    Sarah Yousef Ahmed, Hesa Nazel Al Shammari. Helicobacter pylori Infection: Seroprevalence and Detection of H. Pylori IgG by Using ELISA. Int J Immunol. 2015;3(2):21-26. doi: 10.11648/j.iji.20150302.12

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  • @article{10.11648/j.iji.20150302.12,
      author = {Sarah Yousef Ahmed and Hesa Nazel Al Shammari},
      title = {Helicobacter pylori Infection: Seroprevalence and Detection of H. Pylori IgG by Using ELISA},
      journal = {International Journal of Immunology},
      volume = {3},
      number = {2},
      pages = {21-26},
      doi = {10.11648/j.iji.20150302.12},
      url = {https://doi.org/10.11648/j.iji.20150302.12},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.iji.20150302.12},
      abstract = {Background: Helicobacter pylori (H. pylori), one of the most common bacterial pathogens of humans, colonizes the gastric mucosa. H. pylori is a major factor in inflammatory and malignant diseases of the gastrointestinal tract, where it appears to persist throughout the host's life unless the patient is treated. Materials and methods: A study population was carried out through 100 patients who had gastrointestinal symptoms in Hail region. Seroprevalence of Helicobacter pylori was carried out by detection of H. pylori IgG in patient serum by using Enzyme Linked Immunosorbant Assay (ELISA). Results: Among the patients, H. pylori positivity percentage was found to be (57%) (57/100) in our study. It was found that, the average age of the patient was (one to 70 years old), 68% of them were male and 32% female, the majority came from Hail city. Conclusion: high H.pylori positivity ration (57%), that obtained from these study indicates that H.pylori infection is still a common problem among people in Hail region-Saudi Arabia. The titer of IgG antibody to H.pylori in patient serum can be used as non-invasive tests for the presence of gastric H.pylori infection and gastritis.},
     year = {2015}
    }
    

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  • TY  - JOUR
    T1  - Helicobacter pylori Infection: Seroprevalence and Detection of H. Pylori IgG by Using ELISA
    AU  - Sarah Yousef Ahmed
    AU  - Hesa Nazel Al Shammari
    Y1  - 2015/04/24
    PY  - 2015
    N1  - https://doi.org/10.11648/j.iji.20150302.12
    DO  - 10.11648/j.iji.20150302.12
    T2  - International Journal of Immunology
    JF  - International Journal of Immunology
    JO  - International Journal of Immunology
    SP  - 21
    EP  - 26
    PB  - Science Publishing Group
    SN  - 2329-1753
    UR  - https://doi.org/10.11648/j.iji.20150302.12
    AB  - Background: Helicobacter pylori (H. pylori), one of the most common bacterial pathogens of humans, colonizes the gastric mucosa. H. pylori is a major factor in inflammatory and malignant diseases of the gastrointestinal tract, where it appears to persist throughout the host's life unless the patient is treated. Materials and methods: A study population was carried out through 100 patients who had gastrointestinal symptoms in Hail region. Seroprevalence of Helicobacter pylori was carried out by detection of H. pylori IgG in patient serum by using Enzyme Linked Immunosorbant Assay (ELISA). Results: Among the patients, H. pylori positivity percentage was found to be (57%) (57/100) in our study. It was found that, the average age of the patient was (one to 70 years old), 68% of them were male and 32% female, the majority came from Hail city. Conclusion: high H.pylori positivity ration (57%), that obtained from these study indicates that H.pylori infection is still a common problem among people in Hail region-Saudi Arabia. The titer of IgG antibody to H.pylori in patient serum can be used as non-invasive tests for the presence of gastric H.pylori infection and gastritis.
    VL  - 3
    IS  - 2
    ER  - 

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Author Information
  • Bacteriology, Mycology and Immunology Department, Faculty of Veterinary Medicine, Zagazig University, Zagazig, Egypt; Department of Clinical Laboratory Sciences, College of Applied Medical Science, University of Hail, Hail, Saudi Arabia

  • Department of Clinical Laboratory Sciences, College of Applied Medical Science, University of Hail, Hail, Saudi Arabia

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