International Journal of Immunology

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Relationship Between Parasitic Infections in Diabetic Patients and the Importance of Raman Spectroscopy in Determining Parasites at Molecular Level

Received: 03 December 2019    Accepted: 16 December 2019    Published: 25 December 2019
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Abstract

Diabetes mellitus (DM) is a metabolic disorder of protein, carbohydrate and fat. Insulin secretion, insulin action, or both cause to diabetes mellitus. According to the World Health Organization, the number of diabetic patients in the world is around 200 million and it is stated that this number will reach 300 million in 2025. Parasitic diseases are widespread all over the world and are a major public health problem, especially in underdeveloped or developing countries. It ranks first among the diseases that should be controlled by the World Health Organization. Among the factors causing parasitic diseases include protozoa, helminths and arthropods. In certain geographical areas where parasitic infections are common, many autoimmune diseases such as asthma, rheumatoid arthritis (RA), type1diabetes (T1DM), multiple sclerosis (MS), and inflammatory bowel diseases (IBD) are reported to have a lower incidence. The relationship between helminth infections on the onset and development of T1DM, one of the multigenetic diseases affected by environmental factors, is remarkable. It is not clear how helminth infections prevent T1DM development. In diabetic patients, it is known that there is a decrease in immune system functions, especially cellular immunity, and in these patients CD8 and CD16 values for suppressor T cells and NK cells are decreased compared to normal individuals. Therefore, it does not prevent the development of diabetes and can be seen more in patients with diabetes. Raman Spectroscopy (RS) is a vibrational technique due to inelastic scattering that occurs during the interaction of monochromatic laser beams with molecules. It is preferred in biomedical examinations because RS does not damage the sample and can be obtained quickly by non-invasive method. DM and different parasitic diseases can be determined by analyzing the spectra obtained in RS examinations. The obtained Raman spectra of different molecular systems are different and each system has its own fingerprint.

DOI 10.11648/j.iji.20190704.12
Published in International Journal of Immunology (Volume 7, Issue 4, December 2019)

This article belongs to the Special Issue Parasitology

Page(s) 41-46
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Parasitic Infections, Diabetes Mellitus, Raman Spectroscopy

References
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Author Information
  • Hatay Vocational School of Health Services, Hatay Mustafa Kemal University, Hatay, Turkey

  • Hatay Vocational School of Health Services, Hatay Mustafa Kemal University, Hatay, Turkey

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    Berna Hamamci, Gunes Acikgoz. (2019). Relationship Between Parasitic Infections in Diabetic Patients and the Importance of Raman Spectroscopy in Determining Parasites at Molecular Level. International Journal of Immunology, 7(4), 41-46. https://doi.org/10.11648/j.iji.20190704.12

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    Berna Hamamci; Gunes Acikgoz. Relationship Between Parasitic Infections in Diabetic Patients and the Importance of Raman Spectroscopy in Determining Parasites at Molecular Level. Int. J. Immunol. 2019, 7(4), 41-46. doi: 10.11648/j.iji.20190704.12

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    AMA Style

    Berna Hamamci, Gunes Acikgoz. Relationship Between Parasitic Infections in Diabetic Patients and the Importance of Raman Spectroscopy in Determining Parasites at Molecular Level. Int J Immunol. 2019;7(4):41-46. doi: 10.11648/j.iji.20190704.12

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  • @article{10.11648/j.iji.20190704.12,
      author = {Berna Hamamci and Gunes Acikgoz},
      title = {Relationship Between Parasitic Infections in Diabetic Patients and the Importance of Raman Spectroscopy in Determining Parasites at Molecular Level},
      journal = {International Journal of Immunology},
      volume = {7},
      number = {4},
      pages = {41-46},
      doi = {10.11648/j.iji.20190704.12},
      url = {https://doi.org/10.11648/j.iji.20190704.12},
      eprint = {https://download.sciencepg.com/pdf/10.11648.j.iji.20190704.12},
      abstract = {Diabetes mellitus (DM) is a metabolic disorder of protein, carbohydrate and fat. Insulin secretion, insulin action, or both cause to diabetes mellitus. According to the World Health Organization, the number of diabetic patients in the world is around 200 million and it is stated that this number will reach 300 million in 2025. Parasitic diseases are widespread all over the world and are a major public health problem, especially in underdeveloped or developing countries. It ranks first among the diseases that should be controlled by the World Health Organization. Among the factors causing parasitic diseases include protozoa, helminths and arthropods. In certain geographical areas where parasitic infections are common, many autoimmune diseases such as asthma, rheumatoid arthritis (RA), type1diabetes (T1DM), multiple sclerosis (MS), and inflammatory bowel diseases (IBD) are reported to have a lower incidence. The relationship between helminth infections on the onset and development of T1DM, one of the multigenetic diseases affected by environmental factors, is remarkable. It is not clear how helminth infections prevent T1DM development. In diabetic patients, it is known that there is a decrease in immune system functions, especially cellular immunity, and in these patients CD8 and CD16 values for suppressor T cells and NK cells are decreased compared to normal individuals. Therefore, it does not prevent the development of diabetes and can be seen more in patients with diabetes. Raman Spectroscopy (RS) is a vibrational technique due to inelastic scattering that occurs during the interaction of monochromatic laser beams with molecules. It is preferred in biomedical examinations because RS does not damage the sample and can be obtained quickly by non-invasive method. DM and different parasitic diseases can be determined by analyzing the spectra obtained in RS examinations. The obtained Raman spectra of different molecular systems are different and each system has its own fingerprint.},
     year = {2019}
    }
    

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    AU  - Berna Hamamci
    AU  - Gunes Acikgoz
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    AB  - Diabetes mellitus (DM) is a metabolic disorder of protein, carbohydrate and fat. Insulin secretion, insulin action, or both cause to diabetes mellitus. According to the World Health Organization, the number of diabetic patients in the world is around 200 million and it is stated that this number will reach 300 million in 2025. Parasitic diseases are widespread all over the world and are a major public health problem, especially in underdeveloped or developing countries. It ranks first among the diseases that should be controlled by the World Health Organization. Among the factors causing parasitic diseases include protozoa, helminths and arthropods. In certain geographical areas where parasitic infections are common, many autoimmune diseases such as asthma, rheumatoid arthritis (RA), type1diabetes (T1DM), multiple sclerosis (MS), and inflammatory bowel diseases (IBD) are reported to have a lower incidence. The relationship between helminth infections on the onset and development of T1DM, one of the multigenetic diseases affected by environmental factors, is remarkable. It is not clear how helminth infections prevent T1DM development. In diabetic patients, it is known that there is a decrease in immune system functions, especially cellular immunity, and in these patients CD8 and CD16 values for suppressor T cells and NK cells are decreased compared to normal individuals. Therefore, it does not prevent the development of diabetes and can be seen more in patients with diabetes. Raman Spectroscopy (RS) is a vibrational technique due to inelastic scattering that occurs during the interaction of monochromatic laser beams with molecules. It is preferred in biomedical examinations because RS does not damage the sample and can be obtained quickly by non-invasive method. DM and different parasitic diseases can be determined by analyzing the spectra obtained in RS examinations. The obtained Raman spectra of different molecular systems are different and each system has its own fingerprint.
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