Zebrafish: An in Vivo Model for the Study of Human Diseases
International Journal of Genetics and Genomics
Volume 1, Issue 1, December 2013, Pages: 6-11
Received: Sep. 20, 2013; Published: Nov. 10, 2013
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Authors
Bibhas Kar, Center for Genetic Studies & Research, the Madras Medical Mission, Chennai – 600037, India
Sivamani Subbiah, Center for Genetic Studies & Research, the Madras Medical Mission, Chennai – 600037, India
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Abstract
The zebrafish (Danio rerio) is a powerful model organism for the study of vertebrate biology, being well suited to both developmental and genetic analysis. More recently, the rapid progress of various zebrafish genomics infrastructure initiatives is facilitating the development of zebrafish models of human disease. Genome organization and the pathways involved into control of signal transduction appear to be highly conserved between zebrafish and humans and therefore zebrafish may be used for modeling of human diseases. This review will highlight and describe the utility of zebrafish in the study of human diseases.
Keywords
Zebrafish, Genetics, Development, Human Diseases
To cite this article
Bibhas Kar, Sivamani Subbiah, Zebrafish: An in Vivo Model for the Study of Human Diseases, International Journal of Genetics and Genomics. Vol. 1, No. 1, 2013, pp. 6-11. doi: 10.11648/j.ijgg.20130101.12
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