European Journal of Biophysics

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The Acceleration of DNA may Generate cancer

Received: 06 April 2013    Accepted:     Published: 30 May 2013
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Abstract

In this research, the possibility of generating cancer due to acceleration of DNA is investigated. It is observed that the entanglement between p53 sequence and CG pair is decreased with increasing acceleration .Instead, the entanglement between p53 gene and TA pair is increased with increasing acceleration. Thus the acceleration of p53 leads to mutations from C to T and causes various types of cancer. Also the entanglement between the existence of AT and non-existence of AU pairs in non inertial frames is decreased. It’s concluded that some extra AU pairs maybe produce in DNA structures and cause to cancer or DNA destroy .Furthermore the probability for a site being occupied is increased due to acceleration and more information is transcribed of DNA to protein. It maybe disrupts the cellular dynamics and can lead to cancer. Finally the production cross section for hole in DNA is calculated. Unfortunately information transformation from inside to outside of holes isn’t complete. The proteins outside this hole don’t access to inside the DNA hole and information is lost.

DOI 10.11648/j.ejb.20130102.11
Published in European Journal of Biophysics (Volume 1, Issue 2, April 2013)
Page(s) 16-21
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Acceleration, DNA , Cancer

References
[1] Pui-Man Lam, Yi Zhen, Physical Review E83, 041912 (2011). Michel Peyrard, Santiago Cuesta-Lopez, Dimitar Angelov , Journal of Physics: Condensed Matter 3, 21 (2008) 034103-1-13
[2] Pui-Man Lam, Richard M. Neumann, Physical Review E84, 032901 (2011).Branko Dragovich, Alexandra Dragovich, p-Adic Numbers, Ultrametric Analysis and Applications 1 (2009) 34-41
[3] C. J. Sherr, Cell 234, 116 (2004).
[4] A. Petitjean et al., Hum. Mutat. 28, 622 (2007),
[5] Chi-Tin Shih, Stephan Roche, Rudolf A. Römer, Phys. Rev. Lett. 100, 018105 (2008)
[6] I. Fuentes-Schuller and R. B. Mann, Phys. Rev. Lett. 95, 120404 (2005).
[7] P. M. Alsing, I. Fuentes-Schuller, R. B. Mann, and T. E. Tessier, Phys. Rev. A 74, 032326 (2006).
[8] Qiyuan Pan, Jiliang Jing, Phys.Rev.A77:024302,2008
[9] Alireza Sepehri, Somayyeh Shoorvazi. Information Loss in Transcribing Genetic Sequence from DNA into Protein. American Journal of Bioscience and Bioengineering. Vol. 1, No. 2,2013, pp. 43-47. doi: 10.11648/j.bio.20130102.13
[10] Alireza Sepehri , Somayyeh Shoorvazi. The Possibility of Information Loss in Transcribing Genetic Sequence of DNA into Proteins due to Acceleration of Universe. American Journal of Bioscience and Bioengineering. Vol. 1, No. 2, 2013, pp. 38-42.doi: 10.11648/j.bio.20130102.12.
[11] Jose M. G. Vilar and Leonor Saiz,Phys. Rev. Lett. 96, 238103 (2006)
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Author Information
  • Faculty of Physics, Shahid Bahonar University, Kerman, Iran

  • Islamic Azad University, Neyshabur branch, Neyshabur, Iran

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    Alireza Sepehri, Somayyeh Shoorvazi. (2013). The Acceleration of DNA may Generate cancer. European Journal of Biophysics, 1(2), 16-21. https://doi.org/10.11648/j.ejb.20130102.11

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    Alireza Sepehri; Somayyeh Shoorvazi. The Acceleration of DNA may Generate cancer. Eur. J. Biophys. 2013, 1(2), 16-21. doi: 10.11648/j.ejb.20130102.11

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    AMA Style

    Alireza Sepehri, Somayyeh Shoorvazi. The Acceleration of DNA may Generate cancer. Eur J Biophys. 2013;1(2):16-21. doi: 10.11648/j.ejb.20130102.11

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  • @article{10.11648/j.ejb.20130102.11,
      author = {Alireza Sepehri and Somayyeh Shoorvazi},
      title = {The Acceleration of DNA may Generate cancer},
      journal = {European Journal of Biophysics},
      volume = {1},
      number = {2},
      pages = {16-21},
      doi = {10.11648/j.ejb.20130102.11},
      url = {https://doi.org/10.11648/j.ejb.20130102.11},
      eprint = {https://download.sciencepg.com/pdf/10.11648.j.ejb.20130102.11},
      abstract = {In this research, the possibility of generating cancer due to acceleration of DNA is investigated. It is observed that the entanglement between p53 sequence and CG pair is decreased with increasing acceleration .Instead, the entanglement between p53 gene and TA pair is increased with increasing acceleration. Thus the acceleration of p53 leads to mutations from C to T and causes various types of cancer. Also the entanglement between the existence of AT and non-existence of AU pairs in non inertial frames is decreased. It’s concluded that some extra AU pairs maybe produce in DNA structures and cause to cancer or DNA destroy .Furthermore the probability for a site being occupied is increased due to acceleration and more information is transcribed of DNA to protein. It maybe disrupts the cellular dynamics and can lead to cancer. Finally the production cross section for hole in DNA is calculated. Unfortunately information transformation from inside to outside of holes isn’t complete. The proteins outside this hole don’t access to inside the DNA hole and information is lost.},
     year = {2013}
    }
    

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    JF  - European Journal of Biophysics
    JO  - European Journal of Biophysics
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    UR  - https://doi.org/10.11648/j.ejb.20130102.11
    AB  - In this research, the possibility of generating cancer due to acceleration of DNA is investigated. It is observed that the entanglement between p53 sequence and CG pair is decreased with increasing acceleration .Instead, the entanglement between p53 gene and TA pair is increased with increasing acceleration. Thus the acceleration of p53 leads to mutations from C to T and causes various types of cancer. Also the entanglement between the existence of AT and non-existence of AU pairs in non inertial frames is decreased. It’s concluded that some extra AU pairs maybe produce in DNA structures and cause to cancer or DNA destroy .Furthermore the probability for a site being occupied is increased due to acceleration and more information is transcribed of DNA to protein. It maybe disrupts the cellular dynamics and can lead to cancer. Finally the production cross section for hole in DNA is calculated. Unfortunately information transformation from inside to outside of holes isn’t complete. The proteins outside this hole don’t access to inside the DNA hole and information is lost.
    VL  - 1
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