European Journal of Biophysics

| Peer-Reviewed |

Prevalence of MRSA and Its Antibiotic Susceptibility Pattern in Ujjain, MP.

Received: 15 December 2013    Accepted:     Published: 30 January 2014
Views:       Downloads:

Share This Article

Abstract

Background and objectives: MRSA is known to cause community and hospital acquired infections due to its multiple drug resistance. The objectives of this study were to elucidate the prevalence of MRSA among clinical cases of both community and hospital acquired infections and to evaluate the invitro susceptibility pattern of different antibiotics against isolated MRSA strains. Methods: Clinical samples were collected from both inpatients and outpatients including swabs from operation theatres and ICUs and were subjected to MRSA screening by the conventional methods. Thus isolated MRSA were subjected to antibiotic susceptibility. Results & interpretation: A total of 145 strains of Staphylococcus aureus were isolated. Among these 115 were from indoor patients, 21 from outdoor and 9 were of environmental sources. MRSA was 46% out of the total isolations and MSSA was 54%. The maximum isolation of MRSA was from inpatients (49.5%). The highest isolation rate of 92% of MRSA was reported from blood samples. Vancomycin was the most effective of all drugs used against MRSA strains in invitro susceptibility pattern. On the other hand moxifloxacin and gatifloxacin were the most effective against MSSA strains. Conclusions: MRSA is very much prevalent in this part of the country. A dip in the susceptibility of MRSA to vancomycin, prompts an immediate evolving of an alternate drug.

DOI 10.11648/j.ejb.20130105.11
Published in European Journal of Biophysics (Volume 1, Issue 5, October 2013)
Page(s) 37-40
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

MRSA, MSSA, SA, Methicillin, Environmental Sources

References
[1] Couto I, Melo-cristino J, Fernandes T, Garica N, Serrano MJ, Salgado A et al. Unusually large number of methicillin resistant Staphylococcus aureus clones in a Portuguese hospital. J Clin Microbiol 1995; 33: 2032-2035.
[2] Cox RA, Conquest C, Mallaghan C and Marples RR. A major outbreak of methicillin resistant S. aureus caused by new phage type (EMRSA-16). J Hosp Infect 1995; 29: 87-106.
[3] Vidhani S et al. Study of methicillin resistant S. aureus isolates from high risk patients. Indian J Med Microbiol 2001;19(2):87-90.
[4] Bajaj JK, Karyakarte RP, Kulkarni JD, Deshmukh A.B. Prevalence of resistant Staphylococcus aureus at Aurangabad. J Commun Dis1999; 31(3): 173-176.
[5] Sheagren JN. Staphylococcus aureus, the persistent pathogen. New Eng J Med1984; 310: 1368-1373.
[6] Jevons M Patricia. "Celbenin" - resistant Staphylococci. Br Med J. 1961 14;1(5219):124–125.
[7] Chaudary U, Anupama. Prevalence of methicillin resistant Staphylococcus aureus. Indian J Med Microbiol 1999;17(3):154-155.
[8] Michel M, Gutmann L. Methicillin resistant Staphylococcus and vancomycin resistant enterococci Enterococci, therapeutic realities and possibilities. Lancet 1997; 349: 1901-1906.
[9] Colle JG, Fraser AG, Marmion BP, Simmon A. Mackie and Mc Cartney’s Practical Medical Microbiology. 14 th edition.Churchill Livingstone 1996; 254-256, 796-800.
[10] National Committee for Clinical Laboratory Standards (NCCLS). Performance standards for antimicrobial disk susceptibility tests. Approved standard M2-A7. Wayne (PA): NCCLS 2000.
[11] Majumder D, Sarma Bordoloi JN, Phukan AC, Mahanta J. Antimicrobial susceptibility pattern among methicillin resistant Staphylococcus isolates in Assam. Indian J Med Microbiol 2001;19(3):138-140.
[12] Hanumanthappa AR, Chandrappa NR, Rajasekharappa MG. Prevalence of methicillin resistant Staphylococcus aureus in Karnataka. Indian J Pathol Microbiol 2003;46(1):129-132.
[13] Mathur SK, Singhal S, Prasad KN, Kishore J, Ayyagari A. Prevalence of methicillin resistant Staphylococcus aureus (MRSA) in tertiary care hospital. Indian J Med Microbiol 1994;12(2):96-101.
[14] Kakru DK, Sheikh A, Thaker MA, Wani T. Methicillin resistant Staphylococcus aureus: need for constant surveillance, stringent control and vigorous treatment measues. Indian J Pathol Microbiol 2003;46(1):121-123.
[15] Rajaduraipandi K, Mani KR, Panneerselvam K, Mani M, Bhaskar M, Manikandan P. Prevalence and antimicrobial susceptibility pattern of methicillin resistant Staphylococcus aureus: A multicentre study. Indian J Med Microbiol 2006;24(1):34-38.
Author Information
  • Dept. of Microbiology, RD Gardi Medical College, Surasa, Ujjain, MP, India

Cite This Article
  • APA Style

    L. Suresh Babu. (2014). Prevalence of MRSA and Its Antibiotic Susceptibility Pattern in Ujjain, MP.. European Journal of Biophysics, 1(5), 37-40. https://doi.org/10.11648/j.ejb.20130105.11

    Copy | Download

    ACS Style

    L. Suresh Babu. Prevalence of MRSA and Its Antibiotic Susceptibility Pattern in Ujjain, MP.. Eur. J. Biophys. 2014, 1(5), 37-40. doi: 10.11648/j.ejb.20130105.11

    Copy | Download

    AMA Style

    L. Suresh Babu. Prevalence of MRSA and Its Antibiotic Susceptibility Pattern in Ujjain, MP.. Eur J Biophys. 2014;1(5):37-40. doi: 10.11648/j.ejb.20130105.11

    Copy | Download

  • @article{10.11648/j.ejb.20130105.11,
      author = {L. Suresh Babu},
      title = {Prevalence of MRSA and Its Antibiotic Susceptibility Pattern in Ujjain, MP.},
      journal = {European Journal of Biophysics},
      volume = {1},
      number = {5},
      pages = {37-40},
      doi = {10.11648/j.ejb.20130105.11},
      url = {https://doi.org/10.11648/j.ejb.20130105.11},
      eprint = {https://download.sciencepg.com/pdf/10.11648.j.ejb.20130105.11},
      abstract = {Background and objectives: MRSA is known to cause community and hospital acquired infections due to its multiple drug resistance. The objectives of this study were to elucidate the prevalence of MRSA among clinical cases of both community and hospital acquired infections and to evaluate the invitro susceptibility pattern of different antibiotics against isolated MRSA strains. Methods: Clinical samples were collected from both inpatients and outpatients including swabs from operation theatres and ICUs and were subjected to MRSA screening by the conventional methods. Thus isolated MRSA were subjected to antibiotic susceptibility. Results & interpretation: A total of 145 strains of Staphylococcus aureus were isolated. Among these 115 were from indoor patients, 21 from outdoor and 9 were of environmental sources. MRSA was 46% out of the total isolations and MSSA was 54%. The maximum isolation of MRSA was from inpatients (49.5%). The highest isolation rate of 92% of MRSA was reported from blood samples. Vancomycin was the most effective of all drugs used against MRSA strains in invitro susceptibility pattern. On the other hand moxifloxacin and gatifloxacin were the most effective against MSSA strains. Conclusions: MRSA is very much prevalent in this part of the country. A dip in the susceptibility of MRSA to vancomycin, prompts an immediate evolving of an alternate drug.},
     year = {2014}
    }
    

    Copy | Download

  • TY  - JOUR
    T1  - Prevalence of MRSA and Its Antibiotic Susceptibility Pattern in Ujjain, MP.
    AU  - L. Suresh Babu
    Y1  - 2014/01/30
    PY  - 2014
    N1  - https://doi.org/10.11648/j.ejb.20130105.11
    DO  - 10.11648/j.ejb.20130105.11
    T2  - European Journal of Biophysics
    JF  - European Journal of Biophysics
    JO  - European Journal of Biophysics
    SP  - 37
    EP  - 40
    PB  - Science Publishing Group
    SN  - 2329-1737
    UR  - https://doi.org/10.11648/j.ejb.20130105.11
    AB  - Background and objectives: MRSA is known to cause community and hospital acquired infections due to its multiple drug resistance. The objectives of this study were to elucidate the prevalence of MRSA among clinical cases of both community and hospital acquired infections and to evaluate the invitro susceptibility pattern of different antibiotics against isolated MRSA strains. Methods: Clinical samples were collected from both inpatients and outpatients including swabs from operation theatres and ICUs and were subjected to MRSA screening by the conventional methods. Thus isolated MRSA were subjected to antibiotic susceptibility. Results & interpretation: A total of 145 strains of Staphylococcus aureus were isolated. Among these 115 were from indoor patients, 21 from outdoor and 9 were of environmental sources. MRSA was 46% out of the total isolations and MSSA was 54%. The maximum isolation of MRSA was from inpatients (49.5%). The highest isolation rate of 92% of MRSA was reported from blood samples. Vancomycin was the most effective of all drugs used against MRSA strains in invitro susceptibility pattern. On the other hand moxifloxacin and gatifloxacin were the most effective against MSSA strains. Conclusions: MRSA is very much prevalent in this part of the country. A dip in the susceptibility of MRSA to vancomycin, prompts an immediate evolving of an alternate drug.
    VL  - 1
    IS  - 5
    ER  - 

    Copy | Download

  • Sections