Cancer, the ‘Emperor of All Malady’ has already occupied its position in the list of most fascinating but elusive enigmas in human history like life and consciousness. Existence of phenocopy, C-value paradox and many other electrifying findings has questioned the linear central dogma of molecular biology. This points a paradigm shift towards a stochastic realization of biology. And here, quantum mechanics comes forward with all its experiences in studying the nature’s inherent superposed hierarchy of organizational complexity. Life may be said as information processor that has got the ability to self-organize, driven by the action of consciousness and certainly includes the surrounding environment to form the totality of reality. Any type of noise either subjective or objective causes the fluctuation of this coherent quantum state and can be reduced to a macroscopic disorder that perturbs the biomolecular behavior. These non-local disturbances might be manifested as cancer in a non-deterministic pattern.
| Published in | European Journal of Biophysics (Volume 2, Issue 4) |
| DOI | 10.11648/j.ejb.20140204.12 |
| Page(s) | 38-48 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2024. Published by Science Publishing Group |
Cancer, Consciousness, Quantum Mechanics, C-Value Paradox, Phenocopy
| [1] | Goswani A and Todd D (1997) Is there conscious choice in directed mutation, phenocopies, and related phenomena? An answer based on quantum measurement theory. Integrative Physiological & Behavioral Science 32 (2), 132-143. |
| [2] | Alberts B, Johnson A, Levis J, Raff M, Roberts K, and Walke P (1983) Molecular Biology of the Cell. Garland Science, Taylor and Francis Group. |
| [3] | Goodwin BC (1994) How the Leopard Changed Its Spots, Orion Books, London. |
| [4] | Ho MW (1987) Evolution by process, not by consequence: implications of the new molelcular genetics on development and evolution. Int. J. Comp. Psychol. 1, 3-27. |
| [5] | Abbott D, Davies PCW and Pati AK (2008) The Quantum Aspects of Life. page- 60, 100-103 Imperial College Press. |
| [6] | Lee JJ, Hutner SH, and Bovee, EC (1985) Illustrated Guide to the Protozoa. Allen Press, USA. |
| [7] | Dawkins R (2003) The Information Challenge, pp. 107-122 (quote is from p. 121), Chapter 2.3 of a Devil’s Chaplain; Selected Essays by Richard Dawkins, Ed. Latha Menon, Phoenix. |
| [8] | Birney E et al. (2007) Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature 447,799-816. |
| [9] | de Laat WL, Jaspers NGJ, and Hoeijmakers JHJ (1999) Molecular mechanism of nucleotide excision repair. Genes and Development 13 (7), 768-785. |
| [10] | Mamun MA, Rahman MS, Islam MF, Honi U and Sobhani ME (2011) Molecular biology and riddle of cancer: the ‘Tom & Jerry’ show. Oncol Rev, 5:215–222. DOI 10.1007/s12156-011-0091-2 |
| [11] | Goldthwaite CA (2006) Are stem cells involved in cancer? Regenerative Medicine, 9: 89-96 |
| [12] | Hanahan D and Weinberg RA (2000) The hallmarks of cancer. Cell 100 (1), 57-60. |
| [13] | Reya T, Morrison SJ, Clarke MF and Weissman IL (2001) Stem cells, cancer, and cancer stem cells. Nature 414, 105-111. |
| [14] | Breivik J (2005) The evolutionary origin of genetic instability in cancer development. Cancer Biology 15, 51-60. |
| [15] | Marx J (2002) Debate surges over the origins of genomic defects in cancer. Science 297, 544-546. |
| [16] | Baak JPA, Hermsen MAJA, Meijer G, Schmidt J, Janssen EAM (2003) Genomics and proteomics in cancer, European Journal of Cancer 39, 1199–1215. |
| [17] | Gorgoulis VD et al. (1992) Expression of EGF, TGF-alpha and EGFR in squamous cell lung carcinomas. Anticancer Res 12, 1183-1187. |
| [18] | Davies PCW (2004) Does quantum mechanics play a non-trivial role in life? BioSystems 78, 69–79 |
| [19] | McFadden J and Al-Khalili J (1999) A quantum mechanical model of adaptive mutation. BioSystems 50, 203-211. |
| [20] | Hameroff SR (2004) A new theory of the origin of cancer: quantum coherent entanglement, centrioles, mitosis, and differentiation. BioSystems 77, 119–136. |
| [21] | Klein-Seetharaman J, Oikawa M, Grimshaw SB, Wirmer J et al. (2002) Long-range interactions within a nonnative protein. Science 295, 1719–1722. |
| [22] | Sheldrake R (1981) A new science of life. page-52, 67, 74. |
| [23] | Bohm D (1980) Wholeness and implicate order, page- 191, 247. |
| [24] | Ventegodt S, Hermansen TD, Flensborg-Madsen T, Nielsen ML and Merrick J (2006) Human development VIII: a theory of “Deep” quantum chemistry and cell consciousness: quantum chemistry controls genes and biochemistry to give cells and higher organism’s consciousness and complex behavior. The Scientific World Journal 6, 1441-1453. |
| [25] | Sahtouris E (1999) Earth Dance: Living Systems in Evolution, chapter-3, 13. |
| [26] | Hiley BJ (2008) Quantum Reality Unveiled Through Process and the Implicate Order. Oxford Conference. UK |
| [27] | Koshland J and Daniel E (2002) The Seven Pillars of Life. Science 295 (5563), 2215–2216. |
| [28] | Igamberdiev AU (1993) Quantum mechanical properties of biosystems: A framework for complexity, structural stability, and transformations. BioSystems 31, 65‐73. |
| [29] | Scott AC (1995) Stairway to the mind. New York: Springer-Verlag (Copernicus). |
| [30] | Koestler A (1967) The Ghost in the Machine, page-48. |
| [31] | Penrose R (1994) Shadows of the Mind. Oxford Press, Oxford,UK. |
| [32] | Penrose R (1989) The Emperor’s New Mind. Oxford Press, Oxford, UK. |
| [33] | Sutherland S (1996) International dictionary of psychology. 2nd ed. New York, NY: Crossroad. |
| [34] | Dunne BJ and Jahn RG (2005) Consciousness, information, and living systems. Cellular and Molecular Biology 51, 545-561. |
| [35] | Schr ̈odinger, E (1944) What is life? The physical aspect of the living cell. Cambridge Univ. Press |
| [36] | Engel GS, Calhoun TR, Read EL, Ahn TY, Manal T, Cheng YC, Blankenship RE and Fleming GR (2007). Evidence for wavelike energy transfer through quantum coherence in photosynthetic systems. Nature 446, 782–786 |
| [37] | Chalmers D (1995) Facing up to the problem of consciousness. J Conscious Stud 2:200–219. |
| [38] | Miller GL (1987) Resonance, Information and the Primacy of Process: Ancient Light on Modern Information and Communication Theory and Technology, Doctorial Thesis, Rutgers. |
| [39] | Bateson G (1972) Steps to an ecology of mind. New York: Chandler. |
| [40] | Finklestein D (1969) Space-time Code, Phys. Rev.184, 1261-71. |
| [41] | McIntosh AC (2006) “Functional Information and Entropy in living systems”, pp. 115-126, Design and Nature III: Comparing Design in Nature with Science and Engineering, Vol. 87 of WIT Transactions on Ecology and the Environment, Editor Brebbia, C.A., WIT Press |
| [42] | Fleissner P and Hofkirchner W (1996) Emergent information, Towards a unified information theory, In: BioSystems 2-3 (38), 243-248. |
| [43] | Sober E (1993) The Philosophy of Biology. Boulder CO: Westview Press |
| [44] | Goswami A (2006) A quantum explanation of Shaldrake’s morphic resonance. (http://www.stealthskarter.com/Documents/Consciousness_32.doc) |
| [45] | Hiley BJ (2007) Phase space description of quantum mechanics and non-commutative geometry: Wigner–Moyal and Bohm in a wider context, In: Theo M. Nieuwenhuizen et al (eds.): Beyond the quantum, World Scientific Publishing, ISBN 978-981-277-117-9. |
| [46] | Gould SJ (2002) The Structure of Evolutionary Theory, The Belknap Press of Harvard University Press: Cambridge, MA. |
| [47] | Brink RA (1960) Paramutation and chromosome organization. Q. Rev. Biol. 35, 120–137 |
| [48] | Jorgensen RA (2011) Epigenetics: biology’s quantum mechanics. Front Plant Sci 2, 10. |
| [49] | Rieper E, Anders J and Vedral V (2010) Entanglement at the quantum phase transition in a harmonic lattice. New J. Phys. 12, 025017. |
| [50] | Karsenti E and Vernos I (2001) Science.;294:543–547. |
| [51] | Buhse HEJ and William NE (1982) A comparison of cortical proteins in Tetrahymena vorax microstomes and macrostomes. J Protozool 29(2), 222–226. |
| [52] | Matsuno K and Paton RC (2000) Is there a biology of quantum information? BioSystems 55, 39–46. |
| [53] | Patel A (2001) Why genetic information processing could have a quantum basis. J. Biosci. 26, 145–151. |
| [54] | Davies PCW (2003) The Origin of Life. Penguin, London (Previous title: The Fifth Miracle. Penguin, London and Simon & Schuster, New York, 1998) |
| [55] | Vedral V (2003) Entanglement hits the big time. Nature 425, 28–29. |
| [56] | Schempp W (2003) Replication and transcription processes in the molecular biology of gene expressions: control paradigms of the DNA quantum holographic information channel in nanobiotechnology. BioSystems 68, 119–145. |
| [57] | Home D and Chattopadhyaya R (1996) DNA molecular cousin of Schrodinger’s cat: a curious example of quantum measurement. Phys. Rev. Letts. 76, 2836–2839. |
| [58] | Pati AK and Braunstein S L (2000) Nature. 404, 164 |
| [59] | Olson WK, Gorin AA, Lu XJ, Hock LM, Zhurkin VB (1998) Proc Natl Acad Sci USA 95, 11163-11168. |
| [60] | Zhang Y, Xi Z, Hedge RS, Shakked Z, Crothers DM (2004) Proc Natl Acad Sci USA 101, 8337-8341 |
| [61] | Kalodimos CG, Biris N, Bonvin AMJJ, Levandoski, MM, Guennuegues M, Boelens R and Kaptein R (2004) Science 305, 386-389. |
| [62] | Shoemaker BA, Portman JJ and Wolynes PG (2000) Proc Natl Acad Sci USAs 97, 8868-8873. |
| [63] | Spolar R and Record M (1994) Science 263, 777-784. |
| [64] | Kohler JJ, Metallo SJ, SchneiderT L and Schepartz A (1999) Proc Natl Acad Sci USA 96, 11735-11739. |
| [65] | Slutsky M and Mirny LA (2004) Biophys J 87, 4021-4035. |
| [66] | Goel A, Astumian RD, Herschbach D (2003) Tuning and switching a DNA polymerase motor with mechanical tension. Proc. Natl. Acad. Sci. USA 98, 8485–8491. |
| [67] | Garcia-Viloca M, Gao J, Karplus M, Truhlar DG (2004) How enzymes work: analysis by modern rate theory and computer simulations. Science 303, 186–195. |
| [68] | Genet C, Intravaia F, Lambrecht A and Reynaud S (2004) Electromagnetic vacuum fluctuations,Casimir and Van der Waals forces. Annales de la Fondation Louis de Broglie, Volume 29 no 1-2, 331. |
| [69] | Cairns J, Overbaugh J, Millar S (1988) The origin of mutants. Nature 335, 142–145. |
| [70] | Altenmuller TP, Schenzle A (1993) Dynamics by measurement: Aharonov’s inverse quantum Zeno effect. Phys. Rev. A 48, 70–79. |
| [71] | Altenmuller TP, Schenzle A (1994) Quantum Zeno effect in a double-well potential-a model of a physical measurement. Phys. Rev. A 49, 2016–2027. |
| [72] | Aharonov Y, Vardi M (1980) Meaning of an individual ‘Feynman path’. Phys. Rev. D 21, 2235–2240. |
| [73] | Zink D, Fischer AH and Nickerson JA (2004) Nuclear structure in cancer cells. Nature Reviews, Cancer 4, 677. |
| [74] | Zurek WH (1991) Decoherence and the transition from quantum to classical. Phys. Today, 36–44. |
| [75] | Aloisio R, Blasi P, Galante A, Grillo AF (2004) Phenomenology of Space Time Fluctuations. arXiv:astro-ph/0410413v1 |
| [76] | Zohar D (1990) The Quantum Self: Human Nature and Consciousness Defined by the New Physics, ISBN 0-688-08780-9. |
| [77] | Sobhani ME, Molla AWM, Rahman MS (2010) A review on biomolecular basis of role of psychological stress in the development and progression of cancer. Mag Euro Med Onco 3, 136-142. |
APA Style
Md. Shaifur Rahman, Md. Fahmid Islam, Md. Al Mamun, S. M. Abdul-Awal, Mahbub E. Sobhani. (2014). Evolution of Cancer: A Quantum Mechanical Approach. European Journal of Biophysics, 2(4), 38-48. https://doi.org/10.11648/j.ejb.20140204.12
ACS Style
Md. Shaifur Rahman; Md. Fahmid Islam; Md. Al Mamun; S. M. Abdul-Awal; Mahbub E. Sobhani. Evolution of Cancer: A Quantum Mechanical Approach. Eur. J. Biophys. 2014, 2(4), 38-48. doi: 10.11648/j.ejb.20140204.12
AMA Style
Md. Shaifur Rahman, Md. Fahmid Islam, Md. Al Mamun, S. M. Abdul-Awal, Mahbub E. Sobhani. Evolution of Cancer: A Quantum Mechanical Approach. Eur J Biophys. 2014;2(4):38-48. doi: 10.11648/j.ejb.20140204.12
Share This Article
Twitter
Linked In
Facebook
Copy
Download@article{10.11648/j.ejb.20140204.12,
author = {Md. Shaifur Rahman and Md. Fahmid Islam and Md. Al Mamun and S. M. Abdul-Awal and Mahbub E. Sobhani},
title = {Evolution of Cancer: A Quantum Mechanical Approach},
journal = {European Journal of Biophysics},
volume = {2},
number = {4},
pages = {38-48},
doi = {10.11648/j.ejb.20140204.12},
url = {https://doi.org/10.11648/j.ejb.20140204.12},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ejb.20140204.12},
abstract = {Cancer, the ‘Emperor of All Malady’ has already occupied its position in the list of most fascinating but elusive enigmas in human history like life and consciousness. Existence of phenocopy, C-value paradox and many other electrifying findings has questioned the linear central dogma of molecular biology. This points a paradigm shift towards a stochastic realization of biology. And here, quantum mechanics comes forward with all its experiences in studying the nature’s inherent superposed hierarchy of organizational complexity. Life may be said as information processor that has got the ability to self-organize, driven by the action of consciousness and certainly includes the surrounding environment to form the totality of reality. Any type of noise either subjective or objective causes the fluctuation of this coherent quantum state and can be reduced to a macroscopic disorder that perturbs the biomolecular behavior. These non-local disturbances might be manifested as cancer in a non-deterministic pattern.},
year = {2014}
}
TY - JOUR T1 - Evolution of Cancer: A Quantum Mechanical Approach AU - Md. Shaifur Rahman AU - Md. Fahmid Islam AU - Md. Al Mamun AU - S. M. Abdul-Awal AU - Mahbub E. Sobhani Y1 - 2014/09/20 PY - 2014 N1 - https://doi.org/10.11648/j.ejb.20140204.12 DO - 10.11648/j.ejb.20140204.12 T2 - European Journal of Biophysics JF - European Journal of Biophysics JO - European Journal of Biophysics SP - 38 EP - 48 PB - Science Publishing Group SN - 2329-1737 UR - https://doi.org/10.11648/j.ejb.20140204.12 AB - Cancer, the ‘Emperor of All Malady’ has already occupied its position in the list of most fascinating but elusive enigmas in human history like life and consciousness. Existence of phenocopy, C-value paradox and many other electrifying findings has questioned the linear central dogma of molecular biology. This points a paradigm shift towards a stochastic realization of biology. And here, quantum mechanics comes forward with all its experiences in studying the nature’s inherent superposed hierarchy of organizational complexity. Life may be said as information processor that has got the ability to self-organize, driven by the action of consciousness and certainly includes the surrounding environment to form the totality of reality. Any type of noise either subjective or objective causes the fluctuation of this coherent quantum state and can be reduced to a macroscopic disorder that perturbs the biomolecular behavior. These non-local disturbances might be manifested as cancer in a non-deterministic pattern. VL - 2 IS - 4 ER -
Information
Email: