Nucleic Acids in Atypical Conditions
European Journal of Biophysics
Volume 3, Issue 1, February 2015, Pages: 5-9
Received: Mar. 26, 2015; Accepted: Apr. 17, 2015; Published: Apr. 29, 2015
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Author
Yuri Pivovarenko, Research and Training Center ‘Physical and Chemical Materials Science’ under Kyiv Taras Shevchenko University and NAS of Ukraine, Kiev, Ukraine
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Abstract
Here we describe some properties of nucleic acids, which observed in ‘atypical” experiments. So, we show that physical and chemical properties of nucleic acids depend on dissolved gases. We show particularly that thermal hyperchromism of DNA depends on dissolved oxygen and (or) air. It has been showed most importantly the thermal hyperchromism does not observe for DNA degassed solutions. Here we also demonstrate the difference between some chemical properties of nucleic acids in degassed solutions and in solutions saturated with hydrogen or oxygen. We illustrate too the difference between physical and chemical properties of nucleic acids in the homogenous and gradient-containing solutions; the last case we offer as approximation of the conditions, in which the nucleic acids exist in vivo.
Keywords
DNA, RNA, DNA Hyperchromism, DNA Melting, Phenazine
To cite this article
Yuri Pivovarenko, Nucleic Acids in Atypical Conditions, European Journal of Biophysics. Vol. 3, No. 1, 2015, pp. 5-9. doi: 10.11648/j.ejb.20150301.12
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